| Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS) (NCT05354141) | Direct Biologics, LLC | 2022-07-01 |
| A Reverification of the Berlin Definition Plateau Criteria in Golmud (NCT05493839) | Southeast University, China | 2022-06-20 |
| Mesenchymal Stem Cells (MSCs) in Inflammation-Resolution Programs of Coronavirus Disease 2019 (COVID-19) Induced Acute Respiratory Distress Syndrome (ARDS) (NCT04377334) | University Hospital Tuebingen | 2022-05-01 |
| Effect of Airway Pressure Release Ventilation on Right Ventricular Function Assessed by Transthoracic Echocardiography (NCT05414110) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2022-04-03 |
| Monitorings the Physiological Mechanism of Airway Pressure Release Ventilation in ARDS Patients by EIT (NCT05406427) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2022-03-01 |
| Long-term Impact of COVID-19 Among COVID-19 Patients With Acute Respiratory Distress Syndrome in Brazil (NCT05225194) | Hospital Moinhos de Vento | 2022-02-15 |
| Soluble VE-cadherin in Prediction and Diagnosis of Early Postoperative Hypoxemia After Cardiopulmonary Bypass (NCT05647382) | Zhuan Zhang | 2022-02-01 |
| Effect of Nava on Weaning Outcome in Patients With Mechanical Ventilation (NCT05219643) | Southeast University, China | 2022-01-26 |
| Assessment of Analgesics and Sedatives in Mechanically Ventilated Patients With COVID-19 (NCT05336656) | Wilkes University | 2022-01-01 |
| REcruitment MAneuvers and Mechanical Ventilation Guided by EIT in pARDS (NCT06067152) | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 2022-01-01 |
| Prone Positioning in COVID-19 Patients (NCT05150847) | Tepecik Training and Research Hospital | 2021-12-25 |
| Inhaled ZYESAMI (Aviptadil Acetate) for Treatment of Severe COVID-19 (NCT05137795) | APR Applied Pharma Research s.a. | 2021-12-15 |
| Feasibility and Efficacy of Automated Lateral Decubitus Therapy in Hypoxemic Respiratory Failure (NCT06698913) | University of Sao Paulo General Hospital | 2021-12-13 |
| Mineralocorticoid Use in COVID-19 Patients (NCT05453214) | Ain Shams University | 2021-12-04 |
| Artificial Intelligence in Categorizing the Severity of Oxygenation by Incorporating the PEEP Into the Definition of ARDS in Ventilated Patients (NCT05371314) | National University Health System, Singapore | 2021-12-01 |
| Paradoxical Response to Chest Wall Loading in Mechanically Ventilated Patients (NCT06093958) | HealthPartners Institute | 2021-12-01 |
| Speckle Tracking and Inhaled Nitric Oxide in Acute Respiratory Distress Syndrome (NCT05104606) | Centre Hospitalier Universitaire, Amiens | 2021-11-02 |
| A Randomized Study to Investigate the Effect of Intravenous Imatinib on the Amount of Oxygen in the Lungs and Blood of Adults With COVID-19 Needing Mechanical Ventilation and Supportive Care. (NCT04953052) | Exvastat Ltd. | 2021-10-14 |
| Protective Effect of Sivelestat Sodium on ARDS in Patients With Sepsis (NCT04973670) | Southeast University, China | 2021-10-11 |
| Effectiveness of Recruitment Maneuvers and Lung Protective Ventilation Strategy in ARDS (NCT05023226) | Asia University | 2021-10-05 |
| Effect of Early Treatment With Sivelestat Sodium in ARDS Patients (NCT05020210) | Nanfang Hospital, Southern Medical University | 2021-09-30 |
| The Effect of Tocilizumab on Procalcitonin and Other Biochemical and Clinical Markers in the Setting of COVID-19 Pneumonia (NCT05035589) | Sciberras, Stephen M.D. | 2021-09-20 |
| Effect of Prone Positioning on Mortality in Patients With Mild to Moderate Acute Respiratory Distress Syndrome. (NCT05056090) | University Hospital, Grenoble | 2021-09-01 |
| Study of Allogeneic Adipose-Derived Mesenchymal Stem Cells for Non-COVID-19 Acute Respiratory Distress Syndrome (NCT04909879) | Sorrento Therapeutics, Inc. | 2021-09-01 |
| Physiological Response to Prone Position in COVID-19 Associated Acute Respiratory Distress Syndrome (ARDS) (NCT05092737) | University of Lausanne Hospitals | 2021-08-01 |
| Non-invasive Nervus Vagus Stimulation in Patients With COVID-19 and ARDS (NCT05058742) | Vienna Hospital Association | 2021-07-15 |
| Driving Pressure Guided VT in ARDS Patients (NCT05207267) | Southeast University, China | 2021-06-30 |
| The Effectiveness of Respiratory Tele-rehabilitation After COVID-19 Pneumonia Related: a Randomized Controlled Trial (NCT05007457) | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 2021-06-12 |
| Continuous Flow Ventilation With the Ventijet System in Acute Respiratory Distress Syndrome: a First-in-Human Feasibility and Non-Inferiority Trial (NCT07121257) | Hospital del Mar | 2021-06-08 |
| Ultra-Low Tidal Volume Mechanical Ventilation in ARDS Through ECMO (NCT04832789) | University of Toronto | 2021-06-01 |
| Comparison of ARDS COVID-19 (WHO) vs ARDS Influenza in the ICU (NCT04941092) | Central Hospital, Nancy, France | 2021-06-01 |
| Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS (NCT04536350) | Prof. Dr. Jörg Leuppi | 2021-05-18 |
| Long-Term Functional, Quality-of-Life, Neuropsychological and Cognitive Outcomes in COVID-19 Critical Illness Survivors (NCT04881266) | University of Zurich | 2021-05-07 |
| PLAIAR-Trial: Platelets in Inflammation and Resolution (NCT05098106) | University Hospital Muenster | 2021-05-01 |
| Closed Loop Ventilation in Patients With COVID-19 (NCT04873336) | Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital | 2021-04-01 |
| Breethe Abiomed Recovery RegisTry (BART) (NCT05473130) | Abiomed Inc. | 2021-03-31 |
| FilmArray® and Management of Ventilator Associated Pneumonia in COVID-19 ARDS (NCT05076240) | Centre Hospitalier Universitaire de Nīmes | 2021-03-27 |
| Duration of Prone Position in the Severe Acute Respiratory Syndrome Coronavirus 2 (COVID-19). (NCT05012267) | Ignacio Saez de la Fuente | 2021-03-25 |
| Intravenous Imatinib in Mechanically Ventilated COVID-19 Patients (NCT04794088) | Dr. Jurjan Aman | 2021-03-14 |
| PRONing to Facilitate Weaning From ECMO in Patients With Refractory Acute Respiratory Distress Syndrome (NCT04607551) | Assistance Publique - Hôpitaux de Paris | 2021-03-03 |
| Driving Pressure as a Predictor of Mortality in Acute Respiratory Distress Syndrome Patients (NCT04778228) | Assiut University | 2021-03-01 |
| Study of Intravenous Administration of Allogeneic Adipose-Derived Mesenchymal Stem Cells for COVID-19-Induced Acute Respiratory Distress (NCT04728698) | Sorrento Therapeutics, Inc. | 2021-03-01 |
| Assessment of Lung Mechanics in COVID-19 Acute Respiratory Distress Syndrome (NCT04597853) | University of Zurich | 2021-03-01 |
| Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study (NCT04663802) | University of Pennsylvania | 2021-02-22 |
| Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19 (NCT04360096) | APR Applied Pharma Research s.a. | 2021-02-15 |
| Effect of Two Different Doses of Dexamethasone in Patients With ARDS and COVID-19 (NCT04663555) | Brno University Hospital | 2021-02-02 |
| A Prospective Clinical Study to Explore Response to Prone Positioning in ARDS Patients (NCT04692779) | Rush University Medical Center | 2021-01-31 |
| Almitrine in COVID-19 Patients With ARDS Treated by HFNO (NCT05216575) | Centre Hospitalier Universitaire de Nice | 2021-01-01 |
| The Study of EIT-guided Ventilation Strategy on ARDS Patients (NCT04734340) | Peking Union Medical College Hospital | 2021-01-01 |
| Umbilical Cord Lining Stem Cells (ULSC) in Patients With COVID-19 ARDS (NCT04494386) | Restem, LLC. | 2020-12-23 |
| A First-in-Human Study of AV-001 in Healthy Subjects (NCT04737486) | Vasomune Therapeutics, Inc. | 2020-12-16 |
| Glenzocimab in SARS-Cov-2 Acute Respiratory DistrEss syNdrome Related to COVID-19 (NCT04659109) | Acticor Biotech | 2020-12-16 |
| High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study (NCT04525820) | Prof. Dr. Jörg Leuppi | 2020-12-15 |
| Clinical Decision Support Tool in PARDS Pilot Study (NCT04068012) | Children's Hospital Los Angeles | 2020-12-01 |
| Determine the Effect of Prone Positioning in Adults With ARDS by Electrical Impedance Tomography (NCT04725227) | Shanghai Zhongshan Hospital | 2020-12-01 |
| Careful Ventilation in Acute Respiratory Distress Syndrome (COVID-19 and Non-COVID-19) (NCT03963622) | Unity Health Toronto | 2020-11-23 |
| Stellate Ganglion Blockade in Corona Virus 2019 (COVID-19) Positive Patients (NCT04445337) | University of Nebraska | 2020-11-15 |
| FX06 to Rescue Acute Respiratory Distress Syndrome During Covid-19 Pneumonia (NCT04618042) | Assistance Publique - Hôpitaux de Paris | 2020-11-13 |
| CORONA (COvid pRONe hypoxemiA): Prone Positioning for Hypoxemic COVID-19 Patients With Do-not-intubate Goals (NCT04402879) | University of Calgary | 2020-11-10 |
| Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS) (NCT04581811) | University of Alabama at Birmingham | 2020-11-10 |
| Point-of-care Lung Ultrasound (POCUS)-Integrated Study of Admitted Patients With COVID-19 (NCT05228717) | Olive View-UCLA Education & Research Institute | 2020-11-10 |
| Treatment With Pirfenidone for COVID-19 Related Severe ARDS (NCT04653831) | Soroka University Medical Center | 2020-11-08 |
| Effects of Sevoflurane on Extravascular Lung Water and Pulmonary Vascular Permeability in Patients With ARDS (NCT04530188) | Bicetre Hospital | 2020-11-01 |
| Open-label Multicenter Study to Evaluate the Efficacy of PLX-PAD for the Treatment of COVID-19 (NCT04614025) | Pluristem Ltd. | 2020-10-19 |
| Critical Care Results of SARS-CoV-2 ARDS by Dapsone and Standard COVID-19 Treatment (NCT04918914) | Hunt Regional Medical Center | 2020-10-18 |
| Double-Blind, Multicenter, Study to Evaluate the Efficacy of PLX PAD for the Treatment of COVID-19 (NCT04389450) | Pluristem Ltd. | 2020-10-01 |
| Noninvasive Ventilation in Moderate-to-severe COVID-19-associated Acute Respiratory Distress-syndrome (NCT04667923) | I.M. Sechenov First Moscow State Medical University | 2020-10-01 |
| REgulatory T Cell infuSion fOr Lung Injury Due to COVID-19 PnEumonia (NCT04468971) | Cellenkos, Inc. | 2020-09-29 |
| Extracellular Vesicle Infusion Treatment for COVID-19 Associated ARDS (NCT04493242) | Direct Biologics, LLC | 2020-09-24 |
| Functional Recovery From Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19: Influence of Socio-Economic Status (NCT04556513) | Centre Hospitalier Universitaire Dijon | 2020-09-18 |
| Losartan and Spironolactone Treatment for ICU Patients With COVID-19 Suffering From ARDS (NCT04643691) | Assistance Publique Hopitaux De Marseille | 2020-09-11 |
| Safety and Efficacy of SCD in AKI or ARDS Patients Associated With COVID-19 Infections (NCT04395911) | SeaStar Medical | 2020-09-10 |
| Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19 (NCT04365101) | Celularity Incorporated | 2020-09-02 |
| Right Ventricular Dysfunction in Ventilated Patients With COVID-19 (NCT04764032) | University of Glasgow | 2020-09-02 |
| Ventilatory Efficiency in Critically Ill COVID-19 Patients (NCT04694742) | ASST Fatebenefratelli Sacco | 2020-09-01 |
| Targeted Steroids for ARDS Due to COVID-19 Pneumonia: A Pilot Randomized Clinical Trial (NCT04360876) | University of Colorado, Denver | 2020-09-01 |
| Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19 (NCT04570254) | Unidad Temporal COVID-19 en Centro Citibanamex | 2020-08-19 |
| Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events (NCT04519398) | Grigore T. Popa University of Medicine and Pharmacy | 2020-08-18 |
| Intensive Care Therapy of Covid-19 Disease in Germany (NCT04455451) | University Hospital Tuebingen | 2020-08-06 |
| Dexamethasone Vs Methylprednisolone for the Treatment of Patients With ARDS Caused by COVID-19 (NCT04499313) | Chattogram General Hospital | 2020-08-02 |
| Postural Recruitment Maneuver in Patients With Acute Respiratory Distress Syndrome Due to COVID-19 Infection (NCT04475068) | Hospital Nacional Edgardo Rebagliati Martins | 2020-07-17 |
| Clinical Trial to Evaluate CERC-002 in Adults With COVID-19 Pneumonia and Acute Lung Injury (NCT04412057) | Aevi Genomic Medicine, LLC, a Cerecor company | 2020-07-17 |
| Prone Position for Nonintubated Patients With COVID-19 and Hypoxemic Respiratory Failure (NCT04641182) | Pontificia Universidad Catolica de Chile | 2020-07-06 |
| Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation (NCT06072222) | King Abdul Aziz Specialist Hospital | 2020-07-02 |
| Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation (NCT04553367) | King Abdul Aziz Specialist Hospital | 2020-07-02 |
| Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation (NCT06072248) | King Abdul Aziz Specialist Hospital | 2020-07-02 |
| Comparison of Volume Assist Control, Dual Mode and Airway Pressure Release Ventilation. (NCT04196738) | University Hospital, Angers | 2020-06-30 |
| PROne Positioning in coVID-19 Oxygeno-dependent Patients in Spontaneous Ventilation (PROVID Study) (NCT04366856) | Assistance Publique - Hôpitaux de Paris | 2020-06-26 |
| Follow-up of Critical COVID-19 Patients (NCT04474249) | Uppsala University | 2020-06-25 |
| Prediction of Acute Kidney Injury in Patients With COVID-19 (NCT04406688) | University Hospital Muenster | 2020-06-22 |
| Dornase Alfa for ARDS in Patients With Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) (NCT04402970) | University of Missouri-Columbia | 2020-06-19 |
| One-year Outcomes in Survivors of the Severe COVID-19 Pneumonia (CO-Qo-ICU) (NCT04401111) | Centre Hospitalier Universitaire de Nice | 2020-06-16 |
| Timing of Tracheotomy in Covid-19 Patients (NCT04412356) | Sahlgrenska University Hospital | 2020-06-06 |
| Lung Ultrasound in COVID-19 Patients (NCT04487769) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2020-06-01 |
| A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to COVID-19 (NCT04415073) | Syndax Pharmaceuticals | 2020-05-30 |
| A Study of APL-9 in Adults With Mild to Moderate ARDS Due to COVID-19 (NCT04402060) | Apellis Pharmaceuticals, Inc. | 2020-05-28 |
| Use of Combined Prone Positioning and High-Flow Nasal Cannula, and Non-invasive Positive Pressure Ventilation to Prevent Intubation in COVID-19 Infection (NCT04694638) | Mayo Clinic | 2020-05-21 |
| Plasma Adsorption in Patients With Confirmed COVID-19 (NCT04358003) | Marker Therapeutics AG | 2020-05-20 |
| Clinical Scores for Outcome Prediction in Patients With Severe COVID-19 Pneumonia Requiring ECMO (NCT04405973) | Dr. Alexander Supady | 2020-05-19 |
| Prone Positioning for Patients on General Medical Wards With COVID19 (NCT04383613) | Unity Health Toronto | 2020-05-15 |