| A Study to Assess the Safety and Pharmacokinetics of HBI-002, an Oral Carbon Monoxide Therapeutic, in Healthy Volunteers (NCT03926819) | Hillhurst Biopharmaceuticals, Inc. | 2022-07-25 |
| European Rare Blood Disorders Platform (ENROL) (NCT06250595) | Hospital Universitari Vall d'Hebron Research Institute | 2022-07-01 |
| Metabolic and Hemodynamic Reserve in Pediatric SCA (NCT04406818) | Washington University School of Medicine | 2021-06-30 |
| Folic Acid Supplementation in Children With Sickle Cell Disease (NCT04011345) | University of British Columbia | 2020-11-23 |
| Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease (NCT04584528) | Duke University | 2020-10-27 |
| Daily Vitamin D for Sickle-cell Respiratory Complications (NCT04170348) | Columbia University | 2020-09-15 |
| A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease (NCT04536792) | Agios Pharmaceuticals, Inc. | 2020-07-10 |
| Desmopressin for Bedwetting in Children With SCD (NCT04420585) | Montefiore Medical Center | 2020-07-07 |
| To Assess Safety, Tolerability and Physiological Effects on Structure and Function of AXA4010 in Subjects With Sickle Cell Disease (NCT04134299) | Axcella Health, Inc | 2019-09-25 |
| Specifying Interventions From the Sickle Cell Disease Implementation Consortium (SCDIC) (NCT03380351) | Washington University School of Medicine | 2019-08-26 |
| A Blood Stem Cell Transplant for Sickle Cell Disease (NCT03249831) | City of Hope Medical Center | 2019-01-04 |
| Epidemiology of Silent and Overt Strokes in Sickle Cell Disease (NCT03376893) | Vanderbilt University Medical Center | 2017-06-02 |
| STRIDE Biorepository (NCT02843347) | Emory University | 2017-03-13 |
| Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study (NCT03733249) | Bellicum Pharmaceuticals | 2017-01-01 |
| Hydroxyurea in the Emergency Room to Lessen Pain in Sickle Cell Crisis (NCT03062501) | Instituto Estadual de Hematologia Arthur de Siqueira Cavalcanti | 2016-11-01 |
| SCD-PROMIS: A Software Platform to Enhance Self-efficacy and Patient-provider Engagement for Patients With Sickle Cell Pain (NCT03006718) | Julia Finkel | 2016-11-01 |
| Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis (NCT02411708) | Prolong Pharmaceuticals | 2016-11-01 |
| A Self-Management Intervention for Youth With Sickle Cell Disease and Their Families: Phase I (NCT03069430) | Medical University of South Carolina | 2016-08-01 |
| A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease Patients (NCT02672540) | Prolong Pharmaceuticals | 2016-07-01 |
| Transfusion Treatment in Patients With SCD (NCT03397017) | Società Italiana Talassemie ed Emoglobinopatie | 2016-07-01 |
| tDCS Associated With Peripheral Electrical Stimulation for Pain Control in Individuals With Sickle Cell Disease (NCT02813629) | Faculdade Adventista da Bahia | 2016-03-01 |
| Desmopressin as a Therapy for Bedwetting in Children With Sickle Cell Disease (NCT02636387) | Montefiore Medical Center | 2015-08-26 |
| Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease (NCT02187003) | Biossil Inc. | 2015-06-17 |
| A Study of the Absorption, Metabolism, and Excretion of GBT440 in Healthy Male Subjects (NCT02497924) | Global Blood Therapeutics | 2015-06-01 |
| Preventing Sickle Cell Kidney Disease (NCT02373241) | University of Alabama at Birmingham | 2015-04-01 |
| MBSR for Pain Catastrophizing in SCD (NCT02394587) | Duke University | 2015-04-01 |
| Therapeutic Response Evaluation and Adherence Trial (TREAT) (NCT02286154) | Children's Hospital Medical Center, Cincinnati | 2014-10-01 |
| Feasibility and Efficacy of a Home-based, Computerized Cognitive Training Program in Pediatric Sickle Cell Disease (NCT02857023) | Steven J. Hardy | 2014-10-01 |
| Gene Transfer for Patients With Sickle Cell Disease (NCT02186418) | Children's Hospital Medical Center, Cincinnati | 2014-07-01 |
| Phase 2 Study of MP4CO to Treat Vaso-occlusive Sickle Crisis (NCT01925001) | Sangart | 2013-10-01 |
| Systematic Psychological and Medical Care for Children With SCD (NCT02022891) | Fondation Ophtalmologique Adolphe de Rothschild | 2013-01-01 |
| Carbon Monoxide Levels and Sickle Cell Disease Severity (NCT01547793) | National Heart, Lung, and Blood Institute (NHLBI) | 2012-01-26 |
| Safety Study of MP4CO in Adult Sickle Cell Patients (NCT01356485) | Sangart | 2012-01-01 |
| An Assessment of Prasugrel on Healthy Adults and Sickle Cell Adults (NCT01178099) | Eli Lilly and Company | 2010-07-01 |
| Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease (NCT01054768) | UCSF Benioff Children's Hospital Oakland | 2009-08-01 |
| Skin and Blood Research Samples From Healthy Volunteers and Patients With Hematologic Diseases (NCT00840567) | Washington University School of Medicine | 2009-02-01 |
| Long-Term Effects of Hydroxyurea in Children With Sickle Cell Anemia (The BABY HUG Follow-up Study) (NCT00890396) | National Heart, Lung, and Blood Institute (NHLBI) | 2008-09-01 |
| Parent Educational Program for Children With Sickle Cell Disease (NCT00860782) | University of Miami | 2008-08-01 |
| Far Infrared Radiation for Sickle Cell Pain Management (NCT00599482) | GAAD Medical Research Institute Inc. | 2008-01-01 |
| Study to Determine the Maximum Tolerated Dose, Safety and Effectiveness of Pomalidomide for Patients With Sickle Cell Disease (NCT01522547) | Celgene | 2007-08-01 |
| Establishing a Repository of Blood and DNA Samples From People With Sickle Cell Disease (Comprehensive Sickle Cell Centers Collaborative Genotype-Phenotype Database and Sample Repository) (NCT00528203) | National Heart, Lung, and Blood Institute (NHLBI) | 2007-08-01 |
| Role of Placenta Growth Factor in Sickle Acute Chest Syndrome (NCT00448370) | Children's Hospital Medical Center, Cincinnati | 2007-03-01 |
| Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell Disease (NCT00600665) | University of Illinois at Chicago | 2007-02-01 |
| Dexamethasone to Treat Acute Chest Syndrome in People With Sickle Cell Disease (NCT00530270) | Children's Hospital Medical Center, Cincinnati | 2006-12-01 |
| Stroke With Transfusions Changing to Hydroxyurea (NCT00122980) | St. Jude Children's Research Hospital | 2006-10-01 |
| MAST - Magnesium for Sickle Cell Acute Crisis in Children (NCT00313963) | The Hospital for Sick Children | 2006-04-01 |
| Quality of Life of Children With Sickle Cell Disease Who Are Getting Chronic Transfusions With a Lifeport (NCT00246077) | Children's Mercy Hospital Kansas City | 2005-10-01 |
| Priapism in Boys and Men With Sickle Cell Disease - Demographics, Characteristics and Prevalence (NCT00300235) | University of Texas Southwestern Medical Center | 2005-08-01 |
| Dipyridamole/Magnesium To Improve Sickle Cell Hydration (NCT00276146) | Children's Hospital Medical Center, Cincinnati | 2005-05-01 |
| Establishing a Database of People With Sickle Cell Disease (Comprehensive Sickle Cell Centers Collaborative Data Project [C-Data]) (NCT00529061) | National Heart, Lung, and Blood Institute (NHLBI) | 2005-03-01 |
| Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell Disease (NCT00115336) | Children's Hospital Medical Center, Cincinnati | 2005-01-01 |
| Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease (NCT00528801) | UCSF Benioff Children's Hospital Oakland | 2004-12-01 |
| Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease - Pilot Intervention Study (NCT00850018) | UCSF Benioff Children's Hospital Oakland | 2004-12-01 |
| Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease (NCT00143572) | St. Jude Children's Research Hospital | 2004-11-01 |
| Nitric Oxide Inhalation to Treat Sickle Cell Pain Crises (NCT00094887) | Mallinckrodt | 2004-10-01 |
| Pediatrics:Chlamydia, Sickle Cell Anemia and Stroke Risk - Ancillary to STOP II (NCT00037388) | National Heart, Lung, and Blood Institute (NHLBI) | 2004-07-01 |
| Effectiveness of Arginine as a Treatment for Sickle Cell Anemia (NCT00513617) | UCSF Benioff Children's Hospital Oakland | 2004-06-01 |
| Trial of Oral Glutamine in Patients With Sickle Cell Anemia (NCT00131508) | St. Jude Children's Research Hospital | 2004-05-01 |
| Transcranial Doppler (TCD) Ultrasound of Subjects Enrolled in BABY HUG - Ancillary to BABY HUG (NCT00059293) | National Heart, Lung, and Blood Institute (NHLBI) | 2002-09-01 |
| Pain in Sickle Cell Epidemiologic Study (NCT00035763) | Virginia Commonwealth University | 2001-10-01 |
| Stem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia (NCT00034528) | National Institute of Allergy and Infectious Diseases (NIAID) | 2001-09-01 |
| Induction of Stable Chimerism for Sickle Cell Anemia (NCT00029393) | National Heart, Lung, and Blood Institute (NHLBI) | 2001-08-01 |
| Arginine Treatment of Acute Chest Syndrome (Pneumonia) in Sickle Cell Disease Patients (NCT00029731) | UCSF Benioff Children's Hospital Oakland | 2001-08-01 |
| Stroke Prevention in Sickle Cell Anemia (STOP 2) (NCT00006182) | National Heart, Lung, and Blood Institute (NHLBI) | 2000-07-01 |
| Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia (NCT00029380) | National Heart, Lung, and Blood Institute (NHLBI) | 1999-01-01 |
| Stroke Prevention in Sickle Cell Anemia (STOP 1) (NCT00000592) | Augusta University | 1994-07-01 |
| Pediatric Hydroxyurea in Sickle Cell Anemia (PED HUG) (NCT00000602) | National Heart, Lung, and Blood Institute (NHLBI) | 1994-04-01 |
| Prevention of Cerebral Infarction in Sickle Cell Anemia - Comprehensive Sickle Cell Center (NCT00005327) | University of Southern California | 1993-04-01 |
| Neuropsychological Studies of Children With Sickle Cell (NCT00005438) | National Heart, Lung, and Blood Institute (NHLBI) | 1993-02-01 |
| Multicenter Study of Hydroxyurea in Patients With Sickle Cell Anemia (MSH) (NCT00000586) | National Heart, Lung, and Blood Institute (NHLBI) | 1992-01-01 |
| Indices of Severity and Prognosis for Sickle Cell Disease (NCT00005467) | National Heart, Lung, and Blood Institute (NHLBI) | 1990-01-01 |
| Investigation of Selected Patient Groups From The Cooperative Study of Sickle Cell Disease (NCT00005300) | National Heart, Lung, and Blood Institute (NHLBI) | 1988-10-01 |
| Cerebrovascular Involvement in Sickle Cell Disease - Comprehensive Sickle Cell Center (NCT00005326) | National Heart, Lung, and Blood Institute (NHLBI) | 1988-01-01 |
| Penicillin Prophylaxis in Sickle Cell Disease (PROPS) (NCT00000585) | National Heart, Lung, and Blood Institute (NHLBI) | 1983-08-01 |
| Cooperative Study of The Clinical Course of Sickle Cell Disease (NCT00005277) | National Heart, Lung, and Blood Institute (NHLBI) | 1977-09-01 |