| Phase II/III Randomized, Placebo-controlled Trial of Arimoclomol in SOD1 Positive Familial Amyotrophic Lateral Sclerosis (NCT00706147) | University of Miami | 2009-01-01 |
| Human Spinal Cord Derived Neural Stem Cell Transplantation for the Treatment of Amyotrophic Lateral Sclerosis (NCT01348451) | Neuralstem Inc. | 2009-01-01 |
| A Safety and Tolerability Study of Intracerebroventricular Administration of sNN0029 to Patients With Amyotrophic Lateral Sclerosis (NCT00800501) | Newron Sweden AB | 2008-12-01 |
| Stem Cell Therapy for Amyotrophic Lateral Sclerosis (NCT01984814) | Neurogen Brain and Spine Institute | 2008-12-01 |
| Cell Therapy for Motor Neuron Disease/Amyotrophic Lateral Sclerosis (NCT02242071) | Neurogen Brain and Spine Institute | 2008-12-01 |
| Derivation of Induced Pluripotent Stem Cells From an Existing Collection of Human Somatic Cells (NCT00801333) | Hadassah Medical Organization | 2008-11-01 |
| Clinical Trial of SB-509 in Subjects With Amyotrophic Lateral Sclerosis (ALS) (NCT00748501) | Sangamo Therapeutics | 2008-09-01 |
| Supported Treadmill Ambulation Training (STAT) for Patients Diagnosed With Amyotrophic Lateral Aclerosis (NCT00956488) | Wake Forest University Health Sciences | 2008-09-01 |
| P300 Brain Computer Interface Keyboard to Operate Assistive Technology (NCT00860951) | University of Michigan | 2008-09-01 |
| Identification of Diagnostic And Prognostic Biomarkers From Amyotrophic Lateral Sclerosis (ALS) Skin and Adipose Samples (NCT01948102) | Wake Forest University Health Sciences | 2008-08-20 |
| Involvement of Lymphocyte Type B in Amyotrophic Lateral Sclerosis (ALS) (NCT00846560) | Rambam Health Care Campus | 2008-08-01 |
| Combination Therapy in Amyotrophic Lateral Sclerosis (ALS) (NCT00919555) | Phoenix Neurological Associates, LTD | 2008-06-01 |
| Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral Sclerosis (NCT00877604) | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 2008-06-01 |
| A Multi-Center Controlled Screening Trial of Safety and Efficacy of Lithium Carbonate in Subjects With Amyotrophic Lateral Sclerosis (ALS) (NCT00790582) | Forbes Norris MDA/ALS Research Center | 2008-05-01 |
| Far Infrared Irradiation for Control, Management and Treatment of Amyotrophic Lateral Sclerosis (ALS) (NCT00673140) | GAAD Medical Research Institute Inc. | 2008-05-01 |
| Study of Pioglitazone in Patients With Amyotrophic Lateral Sclerosis (NCT00690118) | University of Ulm | 2008-05-01 |
| Cortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS) (NCT00809224) | University of Michigan | 2008-05-01 |
| Safety and Tolerability Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (NCT00647296) | Knopp Biosciences | 2008-04-09 |
| Hyperlipidemia and Statin Therapy in Amyotrophic Lateral Sclerosis (NCT01592084) | The Methodist Hospital Research Institute | 2008-04-01 |
| Pennsylvania Consortium: Clinical Database (NCT00718445) | Drexel University College of Medicine | 2008-03-01 |
| Cistanche Total Glycosides for Amyotrophic Lateral Sclerosis: A Randomized Control Trial (RCT) Study Assessing Clinical Response (NCT00753571) | Peking University | 2008-01-01 |
| Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis (NCT00560287) | Fondazione Salvatore Maugeri | 2008-01-01 |
| Studies in Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Motor Neuron Disorders (NCT05474235) | Mayo Clinic | 2007-12-01 |
| Feasibility of Telesurveillance and Home Cough Assistance for Amyotrophic Lateral Patients (ALS) (NCT00613899) | Fondazione Salvatore Maugeri | 2007-10-01 |
| Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral Sclerosis (NCT00537446) | Columbia University | 2007-09-01 |
| EEG-Based Brain-Computer Interface Project for Individuals With Amyotrophic Lateral Sclerosis (ALS) (NCT00718458) | Drexel University College of Medicine | 2007-08-01 |
| Comparing The Cyberlink Control System to the Manual Letter Board for Communication Purposes in the ALS Patient Population (NCT00718497) | Drexel University College of Medicine | 2007-08-01 |
| Compassionate Use of Ceftriaxone in Patients With Amyotrophic Lateral Sclerosis (ALS) (NCT00718393) | Drexel University College of Medicine | 2007-06-01 |
| Relationship Between Respiratory Functional Tests and Image Thoracic Techniques in Patients With Neuromuscular Diseases (NCT01090674) | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 2007-06-01 |
| Efficacy of Noninvasive Ventilation in Amyotrophic Lateral Sclerosis (ALS) (NCT00537641) | Columbia University | 2007-05-01 |
| Repetitive Transcranial Magnetic Stimulation (rTMS) in Amyotrophic Lateral Sclerosis (NCT00833820) | Catholic University of the Sacred Heart | 2007-05-01 |
| Electrical Impedance Myography as an Outcome Measure in Amyotrophic Lateral Sclerosis Clinical Trials (NCT00620698) | Beth Israel Deaconess Medical Center | 2007-05-01 |
| Trial of Early Noninvasive Ventilation for Amyotrophic Lateral Sclerosis (ALS) (NCT00580593) | University of Michigan | 2007-04-01 |
| Amyotrophic Lateral Sclerosis (ALS) Tissue Donation Program (NCT00716131) | Drexel University College of Medicine | 2007-04-01 |
| The Effect of Memantine on Functional Outcomes and Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis (ALS) (NCT00409721) | University of Alberta | 2007-03-01 |
| Growth Hormone in Amyotrophic Lateral Sclerosis (NCT00635960) | Federico II University | 2007-03-01 |
| Clinical Trial on the Use of Autologous Bone Marrow Stem Cells in Amyotrophic Lateral Sclerosis (NCT00855400) | Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia | 2007-02-01 |
| Molecular Imaging Modality by Positron Emission Tomography Using 18F-X : Study of Microglial Activation in Amyotrophic Lateral Sclerosis (NCT00563537) | University Hospital, Tours | 2007-01-01 |
| Non-Invasive Measurement of Gastrointestinal (GI) Motility in Patients With Amyotrophic Lateral Sclerosis (ALS) (NCT00714805) | Christine Barr | 2007-01-01 |
| Clinical Trial of Vitamin E to Treat Muscular Cramps in Patients With ALS (NCT00372879) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2006-12-01 |
| G-CSF Treatment for Amyotrophic Lateral Sclerosis: A RCT Study Assessing Clinical Response (NCT00397423) | Peking University | 2006-12-01 |
| Quantitative Measurement of Nutritional Substrate Utilization in Patients With Amyotrophic Lateral Sclerosis (ALS) (NCT00714220) | Drexel University College of Medicine | 2006-11-01 |
| Cerebrospinal Fluid Repository (NCT00714636) | Drexel University College of Medicine | 2006-10-01 |
| Confirmation of Self-Reported Incident ALS Cases in the AARP-Diet and Health (AARP-DH) Cohort (NCT00377351) | National Institute of Environmental Health Sciences (NIEHS) | 2006-09-11 |
| Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS) (NCT00326625) | Teva Pharmaceutical Industries, Ltd. | 2006-07-27 |
| Clinical Trial Ceftriaxone in Subjects With ALS (NCT00349622) | Massachusetts General Hospital | 2006-07-01 |
| Combination Therapy Selection Trial in Amyotrophic Lateral Sclerosis (NCT00355576) | Columbia University | 2006-07-01 |
| Levetiracetam for Cramps, Spasticity and Neuroprotection in Motor Neuron Disease (NCT00324454) | Duke University | 2006-05-01 |
| The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study (NCT00317616) | University of Miami | 2006-04-01 |
| Influence of G-CSF and EPO on Associative Learning and Motor Skills (NCT00298597) | University Hospital Muenster | 2006-03-01 |
| The Effect of Intensive Controlled Exercise in the Early Stages of Amyotrophic Lateral Sclerosis (NCT00160004) | Radboud University Medical Center | 2006-03-01 |
| Mitochondrial Functions and Oxidative Stress in ALS Patients (NCT00331812) | University Hospital, Clermont-Ferrand | 2006-02-01 |
| Amyotrophic Lateral Sclerosis Web Based Patient Care Database: ALSConnection.Org (NCT00302198) | Forbes Norris MDA/ALS Research Center | 2006-01-01 |
| R(+) Pramipexole in Early Amyotrophic Lateral Sclerosis (NCT00140218) | Bennett, James P., Jr., M.D., Ph.D. | 2005-08-01 |
| Memantine for Disability in Amyotrophic Lateral Sclerosis (MEDALS) (NCT00353665) | University of Lisbon | 2005-07-01 |
| Memantine Therapy in Amyotrophic Lateral Sclerosis (NCT01020331) | Phoenix Neurological Associates, LTD | 2005-06-01 |
| Satisfaction Survey for Amyotrophic Lateral Sclerosis (ALS) Patients Comparing Rooms With and Without Assistive Technology (NCT00718107) | Drexel University College of Medicine | 2005-06-01 |
| Noninvasive Examination of the Work of Breathing in Patients With Amyotrophic Lateral Sclerosis (ALS). (NCT00718003) | Drexel University College of Medicine | 2005-05-01 |
| Trial of Sodium Valproate in Amyotrophic Lateral Sclerosis (NCT00136110) | UMC Utrecht | 2005-04-01 |
| Safety Study of Oral Sodium Phenylbutyrate in Subjects With ALS (Amyotrophic Lateral Sclerosis) (NCT00107770) | US Department of Veterans Affairs | 2005-04-01 |
| Clinical Trial of High Dose CoQ10 in ALS (NCT00243932) | Columbia University | 2005-04-01 |
| Clinical Research in ALS Study (NCT00136500) | University of Miami | 2005-02-01 |
| Phase II Study Using Thalidomide for the Treatment of ALS (NCT00140452) | Dartmouth-Hitchcock Medical Center | 2005-02-01 |
| Assessment of the Cyberlink Control System for Use by the Amyotrophic Lateral Sclerosis (ALS) Patient (NCT00718016) | Drexel University College of Medicine | 2004-12-01 |
| A Long-term Extension Study of TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis(ALS) (NCT00230074) | Novartis | 2004-11-01 |
| Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation (NCT00116558) | Edward Kasaraskis | 2004-08-01 |
| Establishment of a Tissue Bank (Blood, CSF) for the Understanding of Motor Neuron Disease (MND) (NCT01950910) | Wake Forest University Health Sciences | 2004-03-29 |
| A Study of the Expression of Nogo and Reticulon Genes in Skeletal Muscle of Patients With Amyotrophic Lateral Sclerosis (NCT00213824) | University Hospital, Strasbourg, France | 2004-02-01 |
| Study Evaluating TCH346 and Placebo Administered Once Daily in Patients With Amyotrophic Lateral Sclerosis (ALS) (NCT00072709) | Novartis Pharmaceuticals | 2003-09-01 |
| Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS) (NCT00125203) | The University of Texas Health Science Center at San Antonio | 2003-07-01 |
| Insulin-like Growth Factor-1 in Amyotrophic Lateral Sclerosis (ALS) Trial (NCT00035815) | Mayo Clinic | 2003-06-01 |
| Minocycline to Treat Amyotrophic Lateral Sclerosis (NCT00047723) | National Institute of Neurological Disorders and Stroke (NINDS) | 2003-01-01 |
| Creatine for the Treatment of Amyotrophic Lateral Sclerosis (NCT00070993) | National Center for Complementary and Integrative Health (NCCIH) | 2002-12-01 |
| Amyotrophic Lateral Sclerosis and Frontotemporal Dementia (NCT00159198) | Assistance Publique - Hôpitaux de Paris | 2002-09-01 |
| Noninvasive Ventilation in ALS Patients With Mild Respiratory Involvement (NCT00386464) | Johns Hopkins University | 2002-04-01 |
| A 12-week, Multicenter, Safety and Dose-ranging Study of 3 Oral Doses of TCH346 in Patients With Amyotrophic Lateral Sclerosis (NCT00036413) | Novartis Pharmaceuticals | 2002-01-01 |
| Effects of Gastrostomy on Amyotrophic Lateral Sclerosis (NCT00337402) | University Hospital, Clermont-Ferrand | 2002-01-01 |
| Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis (NCT00023075) | National Institute of Neurological Disorders and Stroke (NINDS) | 2001-08-01 |
| CARE Canadian ALS Riluzole Evaluation (NCT00542412) | Sanofi | 2001-01-01 |
| Safety/Efficacy of AVP-923 in the Treatment of Emotional Lability (Uncontrolled Crying & Laughing) in Patients With ALS (NCT00021697) | Avanir Pharmaceuticals | 2001-01-01 |
| Amyotrophic Lateral Sclerosis (ALS) Gulf War Study (NCT00007722) | US Department of Veterans Affairs | 2000-07-01 |
| Determinants of Disease Severity in Amyotrophic Lateral Sclerosis (NCT00004457) | National Institute of Neurological Disorders and Stroke (NINDS) | 1998-03-01 |
| Resting Energy Expenditure Equations in Amyotrophic Lateral Sclerosis, Creation of a ALS-specific Equation (NCT03378375) | University Hospital, Limoges | 1996-11-01 |
| Hypermetabolism in ALS Using Six REE Formulas (NCT03382392) | University Hospital, Limoges | 1996-11-01 |
| Exogenous Toxicants and Genetic Susceptibility in ALS (NCT00011154) | National Institute of Environmental Health Sciences (NIEHS) | 1996-09-01 |
| Phase II Study of Leuprolide and Testosterone for Men With Kennedy's Disease or Other Motor Neuron Disease (NCT00004771) | National Center for Research Resources (NCRR) | 1992-10-01 |
| Study of the Effects Strengthening Exercises in Individuals With ALS (NCT00204464) | University of Saskatchewan | |
| Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis (NCT00005766) | National Center for Research Resources (NCRR) | |
| Expanded Access Protocol: Repeated Administration of Nurown® (Autologous MSC-NTF Cells) for the Treatment of ALS (NCT04681118) | Brainstorm-Cell Therapeutics | |
| Treating Amyotrophic Lateral Sclerosis (ALS) With R(+) Pramipexole Dihydrochloride Monohydrate at 60 mg/Day (NCT00596115) | Bennett, James P., Jr., M.D., Ph.D. | |
| RAPA-501 Therapy of ALS Expanded Access Protocol (NCT06169176) | Rapa Therapeutics LLC | |
| A Multicenter, Double-Blind Study to Investigate the Safety and Efficacy of Arimoclomol in Volunteers With ALS (NCT00561366) | CytRx | |
| Intermediate Expanded Access Protocol CNMAu8.EAP04 (NCT06408727) | Clene Nanomedicine | |
| Intermediate-Sized Expanded Access Study (NCT05597436) | Seelos Therapeutics, Inc. | |
| Expanded Access Protocol of BHV-0223 for Patients With Amyotrophic Lateral Sclerosis (ALS) (NCT03537807) | Biohaven Pharmaceuticals, Inc. | |
| IC14 for ALS Patients Expanded Access (NCT04309604) | Implicit Bioscience | |
| Individual Patient Expanded Access IND of Autologous HBadMSCs for the Treatment of Amyotrophic Lateral Sclerosis (NCT04514952) | Hope Biosciences Research Foundation | |
| A Second Intermediate-Size Expanded Access Protocol (EAP) for Pridopidine in People With Amyotrophic Lateral Sclerosis (Pridopidine EAP 2) (NCT06069934) | Prilenia | |
| Two Intermediate Expanded Access Protocols (EAP) CNMAu8.EAP01 and CNMAu8.EAP02 for ALS (NCT05281484) | Clene Nanomedicine | |
| Clinical Trial of Creatine in Amyotrophic Lateral Sclerosis [ALS] (NCT00005674) | National Center for Research Resources (NCRR) | |