| mFOLFOXIRI Plus PD-1 Inhibitor vs mFOLFOX6 as Neoadjuvant Therapy for Locally Advanced Colon Cancer (NCT06890624) | Sun Yat-sen University | 2026-10-01 |
| Cannabis and Opioid Use Disorder, Study 2 (NCT07661446) | University of Kentucky | 2026-10-01 |
| Cognitive Processing Therapy for Posttraumatic Stress Disorder and Co-occurring Lived Experience Stress (NCT07714083) | Boston University | 2026-10-01 |
| Pre-emptive RTO for An Early Detected Gastric Varices in CT/MR Angiogram Trial (NCT07168395) | University of California, Los Angeles | 2026-10-01 |
| Vascular Effects of SGLT2i in Non-diabetic CKD (NCT07060417) | VA Office of Research and Development | 2026-10-01 |
| Multispectral Optoacoustic Tomography in Head and Neck Squamous Cell Cancer (NCT06477003) | University of Oklahoma | 2026-10-01 |
| Metformin-Dapagliflozin Effects on IGF-1 in Male T2DM With MASLD (NCT07778719) | The 95th Hospital of Putian，Putian, Fujian, China | 2026-10-01 |
| Development and Evaluation of the Effectiveness of the SMART-HAND Protocol for Hand Rehabilitation in Patients With Rheumatoid Arthritis (NCT07754552) | Istanbul University - Cerrahpasa | 2026-10-01 |
| Task-Shifting Adapted IPT-A for Youth Suicide Prevention (NCT07383831) | Boston College | 2026-10-01 |
| GLP-1 Plus Lifestyle for Overall Wellness: Find Your Way Forward (NCT06977438) | University of Minnesota | 2026-10-01 |
| A Phase 2 Multicenter Single-Arm Clinical Trial of Zanzalintinib and Pembrolizumab in Subjects With Resectable Clear Cell Renal Cell Carcinoma (NCT07691476) | Yonsei University | 2026-10-01 |
| The Role of Gut and Skin Microbiota in Alopecia Areata (NCT07705217) | Polyclinic GrandMed | 2026-10-01 |
| Implications of Circadian Variation of Human Endocannabinoid Levels on Obesity Risk (NCT03000803) | University of Chicago | 2026-10-01 |
| Ivonescimab Prior to Surgery for the Treatment of High-Risk Localized Clear Cell Renal Cell Cancer (NCT07226544) | City of Hope Medical Center | 2026-10-01 |
| Comparison of Orthodontic Molar Protraction With and Without Adjunctive Surgery (NCT03794726) | University of Alabama at Birmingham | 2026-10-01 |
| Comparing Lower Versus Standard Doses of Belantamab Mafodotin With Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma. (NCT07748689) | Polish Myeloma Consortium | 2026-10-01 |
| AI-Assisted Workflow for Occult Atrial Fibrillation Detection After Ischemic Stroke: A Prospective Randomized Trial (NCT07540065) | National Taiwan University Hospital | 2026-10-01 |
| Concurrent Immunotherapy and Systemic Therapy With Stereotactic Body Radiation Therapy (SBRT) for Stage IV Cancers (COINSSS IV) (NCT07770100) | Mark Bernard | 2026-10-01 |
| The Adaptive Platform Trial for Kidney Disease (NCT07595952) | Nicholas Carlson | 2026-10-01 |
| Development of a Pain Rehabilitation Program for Chronic Pain After SCI (NCT07634796) | Umeå University | 2026-10-01 |
| Evaluating the Effects of a Mindfulness Intervention on Health Outcomes in Individuals With Hypertension (NCT07679984) | Ohio State University | 2026-10-01 |
| A First-in-human Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Anti-tumour Activity of TAX2 in Patients With Relapsed/Refractory Advanced/Metastatic Solid Tumours (NCT07688148) | Apmonia Therapeutics | 2026-10-01 |
| Bispecific CD19/CD20-Targeted Chimeric Antigen Receptor (CAR) Modified T Cells With 4-1BB and Mutated CD28 Costimulatory Domains in Patients With Relapsed or Refractory CD19+ Hematologic Malignancies (NCT07701889) | Roswell Park Cancer Institute | 2026-10-01 |
| Semaglutide Dose Effects on Metabolic and Stress Hormone, Craving and Alcohol Use Outcomes (NCT07772960) | Yale University | 2026-10-01 |
| Impact of GLP-1 Receptor Agonist Therapy on Alcohol Pharmacokinetics (NCT07758231) | University of Wisconsin, Madison | 2026-10-01 |
| A Physical Activity Program Compared to Health Education for Improving Memory and Attention in Hispanic Women With Newly-Diagnosed Stage I-IIIa Breast Cancer, MAMA Trial (NCT07331077) | Mayo Clinic | 2026-10-01 |
| Anti-inflammatory Effect of MgSO₄ in Patients With Moderate Traumatic Brain Injury by Measurming Nucleotide-binding Oligomerization Domain-Like Receptor Pyrin Domain-containing 3 (NLRP3) Inflammasome-a Multiprotein Complex (NCT07763665) | Assiut University | 2026-10-01 |
| Use of Allied-health Professionals to Improve Treatment of Disease (NCT06337799) | University of Iowa | 2026-10-01 |
| PICSTAT Pilot Study for CD8 PET/CT-Guided Lifileucel Treatment in Advanced Melanoma (NCT07700121) | Abramson Cancer Center at Penn Medicine | 2026-10-01 |
| Early Detection of Amyloidosis in Monoclonal Gammopathy Using Nuclear Medicine Imaging (NCT07624760) | University of Zurich | 2026-10-01 |
| Arousal-related Memory Following Theta Burst Stimulation. (NCT07565194) | University of Pennsylvania | 2026-10-01 |
| Smallest Worthwhile Effect of Rotator Cuff Repair and Supervised Exercise (NCT07779876) | Kırklareli University | 2026-10-01 |
| Continuous or Intermittent Cetuximab Plus FOLFIRI as First-line Treatment in RAS/BRAF Wild-type mCRC Patients (NCT07004413) | Charite University, Berlin, Germany | 2026-10-01 |
| 3D MRI Assessment of Femoroacetabular Impingement in Patients With ACL Rupture - Exploratory Study (NCT07271277) | GCS Ramsay Santé pour l'Enseignement et la Recherche | 2026-10-01 |
| Postoperative Pain and Tenesmus After Doppler-Guided Hemorrhoidal Artery Ligation With or Without Mucopexy (NCT07710053) | Ali Genc | 2026-10-01 |
| Effect of Post Operative Low Dose Oral Azithromycin in Chronic Rhinosinusitis Patients With Nasal Polyps (NCT07780292) | Assiut University | 2026-10-01 |
| Cholinergic Enhancement of Theta (NCT07228338) | University of Texas Southwestern Medical Center | 2026-10-01 |
| Steroid Avoidance, Dexamethasone, and RAGE Inhibition for Perioperative Cerebral Edema Management in High-Grade Gliomas (NCT07694089) | Akshitkumar MIstry | 2026-10-01 |
| Analysis of Breath Volatile Organic Compounds Using Mass Spectrometry (NCT07732686) | University of Oklahoma | 2026-10-01 |
| Achilles Tendon Rupture Patient Outcomes at 12 Months (NCT07391553) | Liverpool University Hospitals NHS Foundation Trust | 2026-10-01 |
| ICARE-LCS QUERI Partnered Evaluation Initiative: Integrating Comprehensive Tobacco Treatment to Enhance Lung Cancer Screening (NCT06745258) | VA Office of Research and Development | 2026-10-01 |
| Methylphenidate and Response to Alcohol Cues (NCT07306078) | University of Florida | 2026-10-01 |
| Effect of Missed Dialysis Sessions on Short Term Cardiovascular Events (NCT07455799) | Assiut University | 2026-10-01 |
| Pain After Strabismus Surgery (NCT06689943) | Ann & Robert H Lurie Children's Hospital of Chicago | 2026-10-01 |
| Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have Spread to Bones (NCT06982222) | National Cancer Institute (NCI) | 2026-10-01 |
| Tolerability of Enteral NAC in Infants (NCT06260566) | Sanjiv Harpavat | 2026-10-01 |
| Deep Cervical Lymphovenous Anastomosis for Severe Alzheimer's Disease (NCT07669272) | Southwest Hospital, China | 2026-10-01 |
| Effect of Abdominal Ice Pack After vNOTES Hysterectomy (NCT07626684) | Erzincan Military Hospital | 2026-10-01 |
| MPTA on Full Standing and Rosenberg Views in Patients Undergoing High Tibial Osteotomy (NCT07493733) | Assiut University | 2026-10-01 |
| REverse LuNg Airway and Vascular RemOdeling in Asthma ReMission (ReNORM) (NCT07174713) | Western University, Canada | 2026-10-01 |
| Stress Modulation and Dynamic Balance (NCT07571369) | Kafrelsheikh University | 2026-10-01 |
| Serum sRAGE, CC16, and Syndecan-1 as Predictors of ARDS and Mortality After Severe Chest Trauma (NCT07774338) | Assiut University | 2026-10-01 |
| PATHS-T2D: A Recall-by-Genotype Study of Physiologic and Pharmacologic Responses (NCT07739537) | Massachusetts General Hospital | 2026-10-01 |
| Diaphragmatic Myofascial Release Added to Neck Exercises for Chronic Neck Pain (NCT07761793) | Abdelrahman Alghoul | 2026-10-01 |
| SECURE Post-Market Study (NCT07756489) | Tissium | 2026-10-01 |
| A Trial of Upadacitinib for Non-responsive Eosinophilic Esophagitis (NCT07588568) | University of North Carolina, Chapel Hill | 2026-10-01 |
| Phase II Study of Switching From Dulaglutide to PG-102(MG12) in Type 2 Diabetes Mellitus (NCT07677891) | ProGen. Co., Ltd. | 2026-10-01 |
| Low-Dose Naltrexone For ME/CFS: Dose-Finding (NCT07285473) | University of Alabama at Birmingham | 2026-10-01 |
| Evaluation of the Efficacy of QUITOXIL® in Smoking Cessation (NCT07722832) | KLAVA Innovation | 2026-10-01 |
| Pilot RCT of Computer-based Eye Movement Training (NCT07752563) | Glasgow Caledonian University | 2026-10-01 |
| Pembrolizumab in Combination With Chemotherapy for the Treatment of Frail Hodgkin Lymphoma Patients Ineligible for Standard Treatment (NCT07275216) | City of Hope Medical Center | 2026-10-01 |
| COMUNICAR: Community-Led Family-Centered Communication for Cancer Survivorship Care (NCT07606443) | Stanford University | 2026-10-01 |
| Deposition of Inhaled Liposomal Amphotericin B in Chronic Pulmonary Aspergillosis (CPA) (NCT07530263) | Radboud University Medical Center | 2026-10-01 |
| Multimodality Adaptive Intervention for Post-Inpatient Hospitalization Suicide Risk Reduction (NCT06764108) | Massachusetts General Hospital | 2026-10-01 |
| A Comparative Study of Preoperative Carbohydrate Loading Dose and Fasting on Postoperative Recovery Time in Elective Abdominal Surgery Patients (NCT07562776) | Gulab Devi Hospital | 2026-10-01 |
| Examining the Effectiveness of an Intervention Protocol Based on CO-OP for Children and Adolescents With IDD: A Pilot Study (NCT07737405) | Miri Tal-Saban | 2026-10-01 |
| Feasibility of Cough Skill Training in Individuals With Head and Neck Cancer (NCT07756684) | Boston University Charles River Campus | 2026-10-01 |
| Golcadomide With Pemetrexed, Rituximab, and Dexamethasone for Relapsed and Refractory CNS Lymphomas (NCT07608731) | Allison Winter | 2026-10-01 |
| CHIP in Health and Disease (NCT07780552) | VASCage GmbH | 2026-10-01 |
| Acoustic Stimulation to Study and Modulate Sleepwalking and Related Arousal Disorders (NCT07754838) | Anna Castelnovo | 2026-10-01 |
| Ultrasound-Guided Core Needle Biopsy to Assess Sensitivity and Specificity of Axillary Lymph Node Metastasis in Breast Cancer (NCT07573657) | The First Hospital of Jilin University | 2026-10-01 |
| Enhancing Rehabilitation in Aging Study (ERAS) (NCT07704385) | University of Florida | 2026-10-01 |
| Effects of a 50+ Toothpaste on Halitosis and Oral Comfort in Healthy Adults (NCT07780474) | University of Pavia | 2026-10-01 |
| Using a Personalized Decision Support Tool to Help People With Type 1 Diabetes Manage Exercise (NCT07226583) | Stanford University | 2026-10-01 |
| Treatment of Depression Post-SCI (NCT04263285) | Medical University of South Carolina | 2026-10-01 |
| Outcomes of Left Subclavian Artery Revascularization Strategies During Zone 2 Thoracic Endovascular Aortic Repair (NCT07697820) | Assiut University | 2026-10-01 |
| Duvelisib Maintenance for the Treatment of Peripheral T-Cell Lymphomas (NCT07293403) | City of Hope Medical Center | 2026-10-01 |
| Atherosclerosis in Early Rheumatoid Arthritis Patients Using Atherogenic Index of the Plasma and Carotid Intima Media Thickness (NCT07772466) | Assiut University | 2026-10-01 |
| Testing a Peer-led Trauma-focused Intervention for Significant Others of Those With BPD (NCT06135090) | York University | 2026-10-01 |
| A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus) (NCT06792500) | George Washington University | 2026-10-01 |
| Breast-milk Enema Administration to Stimulate Passage of Meconium (NCT07661992) | Wake Forest University Health Sciences | 2026-10-01 |
| Phase III Study of Topical Fibrinogen-Depleted Human Platelet Lysate Compared to Placebo for Moderate to Severe Dry Eye (NCT06903611) | Cambium Bio Limited | 2026-10-01 |
| Trcheal High-flow for Weaning From Mechanical Ventilation (NCT07714564) | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2026-10-01 |
| A Study to Learn About How Safe Nitroglycerin is and How it Affects the Body When Taken Along With Nurandociguat in People With Coronary Artery Disease (NCT07431294) | Bayer | 2026-10-01 |
| Mapping B-cell Biology Across the Cardiovascular Territories of Giant Cell Arteritis: Towards a New Therapeutic Approach (RituxiMAP GCA) (NCT07269938) | University of Edinburgh | 2026-10-01 |
| Genitourinary Tumors With Sacituzumab Tirumotecan (NCT07716917) | Alianza multidisciplinar para la investigación de los tumores genitourinarios -GUARD | 2026-10-01 |
| Personalised Behavioural Intervention in Cancer Screening Programmes (NCT07722442) | Fundació d'investigació Sanitària de les Illes Balears | 2026-10-01 |
| Inter-Device Concordance of Plantar Thermal Asymmetry Measurement (HIK-DM-2026) (NCT07463456) | Eduardo Luis Martín Javier | 2026-10-01 |
| Exercise and Physical Activity in Adults With Acquired Brain Injury (NCT06895226) | Universidade da Coruña | 2026-10-01 |
| How Healthy Adults Respond to the Nasal Flu Vaccine (NCT07726862) | University of Alabama at Birmingham | 2026-10-01 |
| Integrated Early-CARE for Head & Neck Cancer. (NCT07671573) | Portuguese Oncology Institute, Coimbra | 2026-10-01 |
| Peer-led Community-based PrEP Delivery Among Youth in Brazil (NCT06661356) | University of Alabama at Birmingham | 2026-10-01 |
| Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers (NCT07764809) | IAS Skin Care | 2026-10-01 |
| Wearable Patch Ultrasound Probe for Diagnosis of Liver Stiffness (NCT07716384) | Second Affiliated Hospital of Xi'an Jiaotong University | 2026-10-01 |
| Expediting Pregnancy of Unknown Location Risk Stratification Using the ROM-Plus Point of Care Test (NCT07519954) | University of California, Davis | 2026-10-01 |
| Targeting the Hip Abductors to Reduce Falls in Older Veterans Through A Virtual Multimodal Balance Intervention (NCT07109466) | VA Office of Research and Development | 2026-10-01 |
| Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05) (NCT07711002) | AstraZeneca | 2026-10-01 |
| Comparative Effectiveness of Available Treatments for Sinus and Ear Infections in Children (Acute Otitis Media) (NCT07730814) | Nader Shaikh | 2026-10-01 |
| THERMotherapy Against Persistent Bacterial LUNG Infections (NCT05351242) | Chronic Obstructive Pulmonary Disease Trial Network, Denmark | 2026-10-01 |
| Qing-Xin-Jiao-Tai Decoction for Insomnia Comorbid With Obesity Presenting With Heart-Kidney Non-interaction Syndrome (NCT07754383) | Fohow Pharmaceutical Group | 2026-10-01 |