| Erlotinib in Combination With Select Tyrosine Kinase Inhibitors in Adult Patients With Advanced Solid Tumors (NCT06161558) | National Cancer Institute (NCI) | 2025-07-15 |
| Non-Invasive Measurement of Cardiac Output and Stroke Volume in PE (NCT04855370) | University of California, Los Angeles | 2025-07-15 |
| A Trial of Anti-CD4 Antibody UB-421 in Combination With Optimized Background Antiretroviral Therapy in Patients With Multi-Drug Resistant HIV-1 Infection (NCT05582694) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-07-10 |
| Study of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERAS (NCT05879484) | National Cancer Institute (NCI) | 2025-07-09 |
| A Clinical Trial to Evaluate the Efficacy and Safety of TQA3605 Tablets in Treatment-naive Chronic HBV-infected Subjects (NCT06990776) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2025-07-09 |
| Home-based Exercise for SMI (NCT06078293) | VA Office of Research and Development | 2025-07-02 |
| Esophageal Manometry During Recovery From Endotracheal Intubation (NCT05574465) | University of California, San Francisco | 2025-07-01 |
| Rituximab in Chronic Inflammatory Demyelinating Polyneuropathy (NCT04480450) | University of Kansas Medical Center | 2025-07-01 |
| Prophylactic Analgesia for Bladder Botox Injections (NCT06514430) | Montefiore Medical Center | 2025-07-01 |
| MDMA-Assisted Psychotherapy for Treatment Resistant PTSD in Adolescents (NCT06353282) | University of California, Los Angeles | 2025-07-01 |
| Effect of a Dietary Intervention on Intracellular Lipid Levels, Insulin Sensitivity, and Glycemic Control in Type 2 Diabetes (NCT04088981) | Physicians Committee for Responsible Medicine | 2025-07-01 |
| Empiric Pulsed Field Pulmonary Vein Isolation During Atrial Tachycardia Ablation in Adults With Congenital Heart Disease (NCT06969378) | Boston Children's Hospital | 2025-07-01 |
| A Window of Opportunity Study of Patritumab Deruxtecan in Patients With Brain Metastases (NCT05620914) | Mustafa Khasraw, MBChB, MD, FRCP, FRACP | 2025-07-01 |
| Safety, Tolerability, and Pharmacokinetics of an Oral Withania Somnifera Product in Older Adults (NCT07008300) | Oregon Health and Science University | 2025-07-01 |
| Tislelizumab Combined With Fruquintinib for Metastatic pMMR/MSS Colorectal Cancer (NCT05690035) | Sun Yat-sen University | 2025-07-01 |
| Virtual Parental Presence on Induction of Anesthesia vs Premedication With Midazolam (NCT05834049) | Stanford University | 2025-07-01 |
| Trial of Efficacy of the RetroPerc Device (NCT05022537) | The University of Texas Health Science Center, Houston | 2025-07-01 |
| Robotic Versus Open Comparison in the Surgical Treatment of Wide Abdominal Wall heRnias (ROCSTAR) (NCT05575141) | Algemeen Ziekenhuis Maria Middelares | 2025-07-01 |
| Implementation of a Standardized Tracheostomy Education Discharge Protocol (NCT04741256) | Case Comprehensive Cancer Center | 2025-07-01 |
| Modulation of Sensory Acuity With Transcranial Magnetic Stimulation (TMS) (NCT06234059) | University of Wisconsin, Madison | 2025-07-01 |
| Via, a Hyaluronic Acid (HLA) Based Vaginal Moisturizer Study (NCT07038070) | NYU Langone Health | 2025-07-01 |
| Gait Retraining for Runners With Knee Osteoarthritis (NCT03314428) | University of British Columbia | 2025-07-01 |
| Machine Learning and 3D Image-Based Modeling for Real-Time Body Weight and Body Composition Estimation During Emergency Medical Care. Study 1 (NCT06646120) | Florida Atlantic University | 2025-07-01 |
| Music Therapy and Mindfulness Meditation (NCT06631846) | Universiti Tunku Abdul Rahman | 2025-07-01 |
| The Role of Expectancy for Cognitive Enhancement in College Students Using Prescription Stimulants Nonmedically (NCT04635826) | University of Alabama at Birmingham | 2025-07-01 |
| A Clinical Study Investigating the Therapeutic Effects and Safety of an Investigational Cell Therapy Given With and Without an Additional Investigational Product in Males With Testicular Cancer or a Form of Cancer That Developed From Sperm (NCT06940804) | BioNTech SE | 2025-07-01 |
| Influence of Standardized Perioperative Anesthetic, Analgesic Care on Outcome of Patients Undergoing Hip Fracture Surgeries (NCT06925789) | Milton S. Hershey Medical Center | 2025-07-01 |
| Unrefined Salmon Oil as Dietary Supplement in Patient With Chronic Obstructive Pulmonary Disease (NCT05130294) | Hofseth Biocare ASA | 2025-07-01 |
| Efficacy, Safety, and Pharmacokinetics of FP-014, 11.25 mg in Patients With Advanced Prostate Cancer (NCT06795178) | Foresee Pharmaceuticals Co., Ltd. | 2025-07-01 |
| Allogeneic Cord Blood for Neurological Diseases in Adults (NCT05515419) | The Medical Pavilion Bahamas | 2025-07-01 |
| Clinical Utility of Early vs. Late Blood Biomarker Testing for Alzheimer's Disease (NCT06856681) | C2N Diagnostics | 2025-07-01 |
| Diabetic Cardiomyopathy and Heart Failure (NCT05571865) | University of Louisville | 2025-07-01 |
| Baroreflex Activation Therapy in Left Ventricular Assist Device Patients Study (NCT06195046) | Medical University of South Carolina | 2025-07-01 |
| Nudging Students Towards Healthy Diet and Physical Activity to Prevent Obesity (NCT03128775) | Rio de Janeiro State University | 2025-07-01 |
| Enhancing Recovery Through a Combined Mechanobiologic Intervention Following Meniscus Repair (NCT05505747) | Austin V Stone | 2025-07-01 |
| Beneficial Side Effects of Topiramate in Obese Patients Undergoing Total Joint Arthroplasty (NCT04613024) | Stanford University | 2025-07-01 |
| A Phase 2 Study of IkT-001Pro in Pulmonary Arterial Hypertension (PAH) (NCT06643143) | Inhibikase Therapeutics | 2025-06-30 |
| A Natural History Study in Pediatric Participants With Hearing Loss Due to OTOF, GJB2, or GJB2/GJB6 Mutations (NCT06019481) | Regeneron Pharmaceuticals | 2025-06-30 |
| Golcadomide and Nivolumab in Patients With Non-Hodgkin Lymphoma With Refractory Disease After Chimeric Antigen T-cell Therapy (NCT06767956) | University of Pittsburgh | 2025-06-30 |
| A Study of HY004 Treatment in Adult Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r B-ALL) (NCT06009107) | Juventas Cell Therapy Ltd. | 2025-06-30 |
| A Study to Investigate the Sequencing Strategy of Pirtobrutinib After Disease Progression on First-line Acalabrutinib Treatment for Adult Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT06839872) | AstraZeneca | 2025-06-30 |
| A Study of SRP-9005 in Limb Girdle Muscular Dystrophy Type 2C/R5 Pediatric and Adult Participants (NCT06952686) | Sarepta Therapeutics, Inc. | 2025-06-30 |
| Soft Tissue Stability in the Esthetic Zone: A Randomized Clinical Trial Comparing Vestibular Socket Therapy With Contour Augmentation for Compromised Adjacent Sockets (NCT06673446) | British University In Egypt | 2025-06-25 |
| Neoadjuvant Chemoradiotherapy Plus Sintilimab for MSS, Locally Advanced Rectal Cancer- (NCT06895577) | Sun Yat-sen University | 2025-06-20 |
| Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck (NCT05845307) | M.D. Anderson Cancer Center | 2025-06-20 |
| Vaginal Probiotics During Pregnancy After Premature Rupture of Membranes (NCT06878443) | Centre hospitalier de l'Université de Montréal (CHUM) | 2025-06-17 |
| A Study of LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases (NCT06869278) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-06-17 |
| Comparison of Outcomes for Single vs Double Pyloromyotomy for Gastroparesis Randomized Controlled Trial (NCT06173336) | University of Arkansas | 2025-06-17 |
| A Study of LCAR-AIO in Subjects With Relapsed/Refractory Autoimmune Diseases (NCT06866080) | Nanjing Legend Biotech Co. | 2025-06-17 |
| Safety and Efficacy of Oral Belumosudil in Black or African American, American Indian or Alaska Native, and Native Hawaiian or Other Pacific Islander Male and Female Participants Aged 12 Years and Above With Chronic Graft Versus Host Disease (cGVHD) After At Least 2 Prior Lines of Systemic Therapy (NCT05567406) | Kadmon, a Sanofi Company | 2025-06-16 |
| Clinical Performance Evaluation of the Hativ P30 (NCT06713226) | VUNO Inc. | 2025-06-16 |
| A Study to Evaluate Eciskafusp Alfa in Combination With Bacillus Calmette-guerin (BCG) in Participants With BCG-unresponsive High-risk Non-muscle Invasive Bladder Cancer (NMIBC) (NCT06816017) | Hoffmann-La Roche | 2025-06-15 |
| Phase 1 Dexlansoprazole Delayed-Release Capsules for Acid-Related Disorders in Infants Aged 1 to 11 Months (NCT02442752) | Takeda | 2025-06-15 |
| A Study of TAK-007 in Adults With Refractory Lupus Nephritis (LN) or Refractory Systemic Sclerosis (SSc) (NCT06377228) | Takeda | 2025-06-13 |
| A Phase 2 Trial of Glofitamab for Minimal Residual Disease in Patients With Large B-cell Lymphoma (NCT06670105) | M.D. Anderson Cancer Center | 2025-06-06 |
| Study of Lenvatinib Plus Pembrolizumab in IO Refractory mRCC Patients With Brain Metastases (NCT07011849) | M.D. Anderson Cancer Center | 2025-06-04 |
| Copanlisib and Avelumab as a Maintenance Therapy for Advanced Bladder Cancer (NCT05687721) | VA Office of Research and Development | 2025-06-02 |
| Healthy Living Partnerships for Veterans With Migraine (NCT04373330) | Wake Forest University Health Sciences | 2025-06-01 |
| Dyadic Text-Messaging Micro-Intervention (NCT05917990) | Duke University | 2025-06-01 |
| Trimodality Approach of Low Dose iOnizing Radiation With or Without Neoadjuvant Pembrolizumab and Prostatectomy for Men With Intermediate/High Risk Prostate Cancer (TALON) (NCT04569461) | Duke University | 2025-06-01 |
| A Pharmacokinetic, Safety, and Tolerability Study of LUCEMYRA in the Treatment of Opioid Withdrawal Management in Adolescent Subjects (NCT06711640) | USWM, LLC (dba US WorldMeds) | 2025-06-01 |
| Japanese Bridging Study of Autologous Muscle Derived Cells Compared to Placebo for Female Urinary Sphincter Repair(JPN1) (NCT03997318) | Cook MyoSite | 2025-06-01 |
| Adherence to Otezla (NCT05601492) | Wake Forest University Health Sciences | 2025-06-01 |
| Investigating the Protective Impact of LY-2940094 on Stress-induced Depression- and Anxiety-related Phenotypes in Humans (NCT06786637) | Mclean Hospital | 2025-06-01 |
| Improving Sleep Quality After Total Joint Arthroplasty ( TJA) (NCT03879707) | Stanford University | 2025-06-01 |
| Developing an Intervention to Improve the Non-Technical Skills of the Cardiac Surgical Teams (NCT06257511) | Northwestern University | 2025-06-01 |
| Metformin Versus Standard of Care Treatment in Pregnant Women With Prediabetes (NCT04523363) | Gianna Wilkie | 2025-06-01 |
| Voice, Dyspnea and Acute Respiratory Failure (NCT05340933) | Assistance Publique - Hôpitaux de Paris | 2025-06-01 |
| T2 Biomarkers Predictive Value in Occupational Asthma After Cessation of Exposure. (NCT07006285) | University Hospital, Strasbourg, France | 2025-06-01 |
| Cefepime-taniborbactam vs Meropenem in Adults With VABP or Ventilated HABP (NCT06168734) | Venatorx Pharmaceuticals, Inc. | 2025-06-01 |
| Neuroinflammation and Age-associated Brain Pathology: Two Potential Mechanisms of Cognitive Impairment in Ovarian Cancer (NCT04542603) | University of Alabama at Birmingham | 2025-06-01 |
| Effect of Oral Isosorbide Mononitrate Plus Amlodipine Antispasm Therapy on Outcomes of Radial Artery Grafts After CABG (NCT06730945) | Ruijin Hospital | 2025-06-01 |
| Vorinostat in Combination With Chemoradiation in Locally Advanced HPV Negative HNSCC (NCT05608369) | Case Comprehensive Cancer Center | 2025-06-01 |
| A Study of Amantadine for Cognitive Dysfunction in Patients With Long-Covid (NCT06234462) | University of Texas Southwestern Medical Center | 2025-06-01 |
| Dementia Prevention Internet-Based Intervention: Randomized Controlled Trial and Knowledge Translation (NCT06911047) | McMaster University | 2025-06-01 |
| Quality of Life Assessment of Radiotherapy in Recurrent Head and Neck Cancer (NCT05850663) | University of Oklahoma | 2025-06-01 |
| Developing and Pilot Testing a Remote Smoking Cessation Digital Therapeutic for Individuals With Serious Mental Illness (NCT05031416) | Johns Hopkins University | 2025-06-01 |
| Foundations for Prescribing Song-Based Therapies: A Quantitative Comparison of Laryngeal Exercises (NCT07595315) | University of Kansas Medical Center | 2025-06-01 |
| The Role of Glutathione Deficiency and MSIDS Variables in Long COVID-19 (NCT05371288) | University of California, Irvine | 2025-06-01 |
| Molecular Neuroimaging to Assess the Link Between Neuroinflammation and Cognitive Impairment in Breast Cancer (NCT04364672) | University of Alabama at Birmingham | 2025-06-01 |
| Accuracy of the Set Tidal Volume During Intraoperative Mechanical Ventilation (NCT06232915) | Joseph D. Tobias | 2025-06-01 |
| Trachoma Elimination Study by Focused Antibiotic (TESFA) (NCT03523156) | Emory University | 2025-06-01 |
| Conventional Instrumentation, Computer Navigation, and Robotic Assistance Techniques in TKA (NCT05629715) | University of California, Los Angeles | 2025-06-01 |
| A Study Evaluating the Safety, Tolerability, and Efficacy of Aramchol Meglumine in Primary Sclerosing Cholangitis (NCT06095986) | Galmed Pharmaceuticals Ltd | 2025-06-01 |
| The Interplay Between Oxalate, Immunity and Infection (NCT04605055) | University of Alabama at Birmingham | 2025-06-01 |
| Augmented Reality-based Telerehabilitation Platform for Patients With Stroke (NCT06963645) | Stanford University | 2025-06-01 |
| Efficacy, Safety, and Pharmacokinetics of FP-014, 22.5 mg in Patients With Advanced Prostate Cancer (NCT06795191) | Foresee Pharmaceuticals Co., Ltd. | 2025-06-01 |
| Abscopal Effect From Low-dose Radiotherapy in Metastatic Cancer Combined With Stereotactic Body Radiotherapy (NCT05578274) | Soonchunhyang University Hospital | 2025-06-01 |
| Effect of Sevoflurane and Desflurane on Heme Oxygenase-1 Expression in Elective Cholecystectomy (NCT06457958) | Kocaeli City Hospital | 2025-06-01 |
| Evaluation of AcrySof IQ Vivity Extended Vision Intraocular Lenses (NCT06541795) | Alcon Research | 2025-06-01 |
| TCR1020-CD8 T Cells in KRAS-mutated Cancers (NCT06707896) | University of Pennsylvania | 2025-06-01 |
| A Window of Opportunity Study of Black Raspberry for Patients With HNSCC (NCT06086925) | Mitchell Machtay | 2025-06-01 |
| Datopotamab Deruxtecan (Dato-DXd) for Non-Small Cell Lung Cancer (NSCLC) Patients With Active Brain Metastases (NCT06676917) | MedSIR | 2025-06-01 |
| Health-Economic Evaluation of Early Diagnosis of Epithalial Ovarian Cancer Recurrence Using the ROMA Score: a Prospective Multicenter Randomized Trial (NCT05991752) | University Hospital, Tours | 2025-05-31 |
| Study of Safety and Effects of Garetosmab in Healthy Obese Men and Post-Menopausal Women (NCT06970405) | Regeneron Pharmaceuticals | 2025-05-29 |
| Identification of Genomic Biomarkers for Rheumatoid Arthritis With Late Onset (NCT05808309) | Centre Hospitalier Sud Francilien | 2025-05-28 |
| TCRαβ/CD19 Depletion of Stem Cell Grafts for Transplant (NCT05968170) | Neena Kapoor, M.D. | 2025-05-27 |
| A Study of Bimagrumab (LY3985863) and Tirzepatide (LY3298176), Alone or in Combination, in Participants With Obesity or Overweight With Type 2 Diabetes (NCT06901349) | Eli Lilly and Company | 2025-05-23 |
| A Post-marketing Surveillance to Assess the Safety and Effectiveness of Zirabev in Domestic Patients With Various Cancer (NCT04889495) | Pfizer | 2025-05-16 |
| Assessing AI for Detecting Lung Nodules and Cancer: Pre- and Post-Deployment Study (NCT06746324) | University of Florida | 2025-05-15 |