| Bispecific T-Cell Engager Tarlatamab and TROP2 Targeted Antibody Drug Conjugate Sacituzumab Govitecan in Previously Treated Extensive-Stage Small Cell Lung Cancer and Extrapulmonary Neuroendocrine Cancer (NCT07328490) | National Cancer Institute (NCI) | 2026-04-25 |
| Transcranial Magnetic Stimulation for Youth With Treatment-Resistant Major Depressive Disorder (NCT05652465) | National Institute of Mental Health (NIMH) | 2026-04-25 |
| Study to Evaluate the Therapeutic Equivalence and Safety of Fluticasone Furoate and Vilanterol Inhalation Powder 100 mcg/25 mcg and BREO ELLIPTA 100 mcg/25 mcg in Participants With Asthma (NCT07223294) | Sandoz | 2026-04-21 |
| RAFT-TAVR PACE: LBBAP vs. RVP Post-TAVR in Patients Requiring PPI (NCT06857201) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2026-04-16 |
| Study of Nogapendekin Alfa Inbakicept and iNKT Cells in Critically Ill Adults With Severe Community-Acquired Pneumonia (NCT07492875) | ImmunityBio, Inc. | 2026-04-15 |
| Nogapendekin Alfa-Inbakicept and iNKT Cells for Critically Ill Adults With Severe Community-Acquired Pneumonia (With or Without Sepsis/ARDS) (NCT07492888) | ImmunityBio, Inc. | 2026-04-15 |
| Molecular Surveillance In Early Breast Cancer Using The Tumor-Informed ctDNA Assay Myriad Genetics Precise MRD Test; A Prospective Observational Multicenter Study (The MRD Molecular Surveillance Study) (NCT07475923) | M.D. Anderson Cancer Center | 2026-04-09 |
| A Study to Learn More About How Safe Nurandociguat is and How it Affects the Way the Body Processes Rosuvastatin and Dabigatran in Healthy Adults (NCT07515339) | Bayer | 2026-04-08 |
| Quality of Care for Adolescent and Young Adult (AYA) Patients Living With Serious or Advanced Cancer (NCT07484282) | National Cancer Institute (NCI) | 2026-04-07 |
| The Mepilex Cesarean Delivery Trial (NCT07066254) | Montefiore Medical Center | 2026-04-01 |
| Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction (NCT07115056) | Campbell Clinic | 2026-04-01 |
| Phase II Trial Evaluating the Safety and Efficacy of the Combination of Zimberelimab, Domvanalimab and Sacituzumab Govitecan as 1L Therapy for PD-L1 Positive Advanced TNBC (NCT07134556) | MedSIR | 2026-04-01 |
| A Phase 3, Double-blind/Double-dummy, Safety/Efficacy/Superiority of Sibutramine/Topiramate XR in Adults With Overweight (NCT05209984) | Eurofarma Laboratorios S.A. | 2026-04-01 |
| Efficacy and Safety of the N0750 Compared to Monotherapies in the Treatment of Painful Diabetic Peripheral Neuropathy (NCT06715462) | Eurofarma Laboratorios S.A. | 2026-04-01 |
| Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea (ARCTIC_AUS) (NCT07021833) | Cryosa, Inc. | 2026-04-01 |
| Light Therapy to Treat Depression in Pediatric Stem Cell Therapy Recipients (NCT06496477) | St. Jude Children's Research Hospital | 2026-04-01 |
| Selvigaltin With Standard of Care Treatment for the Treatment of Relapsed/Refractory Multiple Myeloma (NCT07082270) | Roswell Park Cancer Institute | 2026-04-01 |
| Dronabinol As an Adjunct for Reducing Pain (DARP)-Texas Children's Hospital (NCT06834997) | Baylor College of Medicine | 2026-04-01 |
| Between Urgency and Efficiency: Assessing the Feasibility of Implementing a Protocol for the Care of Extremely Premature and Very Low Birth Weight Infants During the First Hour of Life: GOLD Study (NCT07461623) | Centre Hospitalier Universitaire de Nice | 2026-04-01 |
| An Intervention to Reduce Discrepancy in Everyday Preferences (NCT03577418) | Mclean Hospital | 2026-04-01 |
| A Phase 1 Study of Cizutamig in IgE Mediated Diseases (NCT07408869) | Candid Therapeutics | 2026-04-01 |
| Electronic Health Record-Integrated Patient-Generated Data (NCT06668870) | Wake Forest University Health Sciences | 2026-04-01 |
| Multi-component Remote Assessment in Adult Survivors Using a Connected Technology Platform for Healthcare Delivery (NCT07222358) | St. Jude Children's Research Hospital | 2026-04-01 |
| Cognitive Effects of Bioavailable Curcumin (NCT07251985) | University of California, Los Angeles | 2026-04-01 |
| Lung Cancer Screening CT for Firefighters (NCT06836414) | University of California, San Francisco | 2026-03-31 |
| Spesolimab Post-marketing Surveillance in Korean Patients With Flares With Generalized Pustular Psoriasis (NCT06886009) | Boehringer Ingelheim | 2026-03-31 |
| Study to Investigate Petosemtamab in Adults With Metastatic Non-Small Cell Lung Cancer (NCT07353957) | Merus B.V. | 2026-03-27 |
| Milieu Teaching-AV (MT-AV Pilot) (NCT06794476) | Father Flanagan's Boys' Home | 2026-03-18 |
| Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult Smokers (NCT02974582) | National Institute on Minority Health and Health Disparities (NIMHD) | 2026-03-17 |
| Alrizomadlin (APG-115) in Subjects With BAP1 Cancer Syndrome and Early-Stage Mesothelioma (NCT06654050) | National Cancer Institute (NCI) | 2026-03-16 |
| A Study to Evaluate Crovalimab in People With Antiphospholipid Syndrome (APS) (NCT07172022) | Hoffmann-La Roche | 2026-03-16 |
| Feasibility of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Knee Surgery (NCT07336355) | University of California, San Diego | 2026-03-14 |
| Operation Calm: VR Nature-Based Mindfulness to Reduce Pediatric Surgical Anxiety (NCT07694934) | McGill University | 2026-03-10 |
| Essential Amino Acids and Parkinsons Disease (NCT06604065) | University of Arkansas | 2026-03-09 |
| Effect of Intrarectal Ice Application on Pain, Anxiety, Cortisol Levels, Development of Complications, and Hospital Readmission in Transrectal Ultrasound-Guided Prostate Biopsy (NCT07462390) | Tarsus University | 2026-03-03 |
| KSD-201 Treatment for Advanced Clear Cell Renal Cell Carcinoma: an Early Exploratory Clinical Study (NCT06708936) | Kousai Bio Co., Ltd. | 2026-03-01 |
| FCI Effectiveness in NAFLD Stratification (NCT05827432) | NHS Grampian | 2026-03-01 |
| The Role of Perturbed Auditory Information for Self-motion in Gait (NCT05713383) | University of Nebraska | 2026-03-01 |
| A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Maintenance of Healing in Participants With Healed Erosive Esophagitis (EE) Due to Gastroesophageal Reflux Disease (GERD) (NCT07313774) | Cinclus Pharma Holding AB | 2026-03-01 |
| Parallel, Double-dummy, Superiority Study Levocetirizine/Pseudoephedrine x Zina for Allergic Rhinitis in Brazil (NCT05637710) | Eurofarma Laboratorios S.A. | 2026-03-01 |
| UCAR T-cell Therapy Targeting CD19/ BCMA(QT-019C) in Patients With Relapse/ Refractory Autoimmune Diseases (NCT07410377) | The Affiliated Hospital of Xuzhou Medical University | 2026-03-01 |
| Monitoring Early Response to Targeted Therapy in Stage IV HER2+ Breast Cancer Patients With Advanced PET/MR Imaging (NCT04273555) | University of Alabama at Birmingham | 2026-03-01 |
| Flange Fitting for NICU Pumping Parents to Explore Improved Milk Production and Satisfaction (NCT07268105) | University of Maryland, Baltimore | 2026-03-01 |
| A Study of Mitapivat in Participants With Sickle Cell Disease and Nephropathy (NCT06286046) | Agios Pharmaceuticals, Inc. | 2026-03-01 |
| A Study to Assess CLBR001+SWI019 in Subjects With Autoimmune Diseases (NCT06913608) | Calibr, a division of Scripps Research | 2026-03-01 |
| NOTIFY (New Observations Taking Information From Yesterday) (NCT05977413) | Stanford University | 2026-03-01 |
| Cerebral Hemodynamics and Oxygenation in Critically Ill Patients (NCT04690530) | Centre Hospitalier Universitaire de Nice | 2026-03-01 |
| A Novel Haemostatic Agent for Robotic Partial Nephrectomy (NCT07284953) | The Royal Wolverhampton Hospitals NHS Trust | 2026-03-01 |
| ASCs in Recently Diagnosed Non-ischemic Heart Failure (NCT06840275) | Cell to Cure ApS | 2026-03-01 |
| Value of Advanced MRI Techniques in the Assessment of Endometriosis (NCT06481982) | University of Zurich | 2026-03-01 |
| Cost-effectiveness Analyses for the Prevention of Acute Kidney Injury in Patients Undergoing Cardiac Surgery in the UK (NCT07108634) | The Royal Wolverhampton Hospitals NHS Trust | 2026-03-01 |
| A Study to Evaluate Efficacy and Safety of Anakinra in Chinese Patients With Colchicine-resistent FMF (NCT06666335) | Swedish Orphan Biovitrum | 2026-03-01 |
| Compare Airway Pressure Release Ventilation (APRV) to Conventional Mechanical Ventila (NCT07111039) | H. Lee Moffitt Cancer Center and Research Institute | 2026-03-01 |
| Intracervical Balloon Placement With Nitrous Oxide Administration (NCT06498908) | Olivia Sher | 2026-03-01 |
| Exercise Training for Brachial Plexus Injury Following Nerve Transfer (NCT05859178) | University of Alberta | 2026-03-01 |
| L9LS-R21 Interaction (NCT07208760) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-03-01 |
| Persistence of Oral DNA Adducts in Smokers and Vapers (NCT06983392) | University of Minnesota | 2026-03-01 |
| Abbreviated Biparametric MRI (RSI + T2WI) for Prostate Cancer Detection: Correlation With Histopathology (NCT05046782) | M.D. Anderson Cancer Center | 2026-02-28 |
| Comparison Of Cytology And Molecular Screening For Detecting Cervical Reactive Cellular Changes In General Population (NCT07211204) | Timser SAPI de CV | 2026-02-27 |
| N2O for Acute Suicidality and Depression in the ED (NCT05710887) | University of Chicago | 2026-02-27 |
| CBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer (NCT06730100) | National Cancer Institute (NCI) | 2026-02-17 |
| N-803 in Combination With Pembrolizumab and Enfortumab Vedotin for Treatment of Urothelial Cancer (NCT07217496) | Vadim S Koshkin | 2026-02-15 |
| Efficacy of Superoxide Dismutase Spray in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer . (NCT07400016) | West China Hospital | 2026-02-10 |
| A Trial to Evaluate the Safety and Immunogenicity of VLA1553 in Healthy Children (NCT07133178) | Valneva Austria GmbH | 2026-02-06 |
| Efficacy of Superoxide Dismutase in Preventing Radiation Dermatitis in Patients With Head and Neck Cancer . (NCT07399990) | West China Hospital | 2026-02-04 |
| PREcision meDICine in Treatment in CardioVascular Disease (NCT07369141) | Maastricht University Medical Center | 2026-02-01 |
| Study of NP-101 in Patients With Unresectable Hepatocellular Carcinoma (HCC) Undergoing Y-90 Treatment (NCT06217094) | University of Florida | 2026-02-01 |
| Phase I Study of Safety and Feasibility of Transarterial Embolization of Incurable Hypervascular Pediatric Soft Tissue Sarcomas (NCT07136571) | University of Alabama at Birmingham | 2026-02-01 |
| Minimally Invasive Open Excisional Hemorrhoidectomy Compared to Conventional Open Excisional Hemorrhoidectomy: a Clinical Trial (NCT06764849) | Hospital Son Llatzer | 2026-02-01 |
| Ketamine in Central Sensitization (NCT07182032) | University Hospitals Cleveland Medical Center | 2026-02-01 |
| Autoimmune Protocol Diet Intervention on Proteinuria in IgA Nephropathy Patients (NCT07022574) | University of California, Los Angeles | 2026-02-01 |
| Study to Evaluate Safety and Dosimetry of [18F]GEH121224 in Patients With Locally Advanced or Metastatic Breast Cancer (NCT05634954) | GE Healthcare | 2026-02-01 |
| Middle Meningeal Artery Embolization for Chronic Migraine (NCT07044648) | Wake Forest University Health Sciences | 2026-02-01 |
| Semaglutide and Polycystic Ovarian Syndrome: an Emerging Treatment Strategy (NCT06222437) | Methodist Health System | 2026-02-01 |
| Stromal Vascular Fraction (SVF) for Knee Post-Trauma Osteoarthritis (PTOA) (NCT05515523) | Wake Forest University Health Sciences | 2026-02-01 |
| Asthma and Osteopathic Manipulative Technique (NCT07071194) | University Hospitals Cleveland Medical Center | 2026-02-01 |
| N-803 Maintenance Therapy Post CAR T-cell Therapy in Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphomas (NCT07049432) | University of Utah | 2026-02-01 |
| A Cataract Surgery Clinical Trial (NCT07044674) | Alcon Research | 2026-02-01 |
| A Multi-Site Study of MDMA-Assisted Psychotherapy for Eating Disorders (NCT04454684) | Resilient Pharmaceuticals | 2026-02-01 |
| A Clinical Cohort Registry Study on Primary PCI for Acute Myocardial Infarction at Zhongshan Hospital (NCT07400601) | Shanghai Zhongshan Hospital | 2026-02-01 |
| A Study to Evaluate the Efficacy and Safety of Inavolisib When Administered in Combination With Bevacizumab and FOLFOX or FOLFIRI as First Line Therapy in Participants With Colorectal Cancer (NCT07323576) | Hoffmann-La Roche | 2026-02-01 |
| Intrathecal Hydromorphone vs Intrathecal Morphine to Treat Post Cesarean Pain in Patients With Opioid Use Disorder Taking Buprenorphine (NCT06784180) | University of North Carolina, Chapel Hill | 2026-02-01 |
| Zimberelimab + Domvanalimab in Gastroesophageal Adenocarcinoma (NCT07283848) | Massachusetts General Hospital | 2026-02-01 |
| A Non-randomised, Non-inferiority Comparative Study of Oral Actiskenan (Morphine Sulfate) Versus Intranasal Sufentanil in the Early Management of Severe Acute Pain in Emergency Departments. (NCT07344350) | Groupe Hospitalier de la Region de Mulhouse et Sud Alsace | 2026-01-31 |
| Fibrinogen in Liver Transplant Subjects (NCT06764927) | Ezeldeen Abuelkasem | 2026-01-31 |
| Diversion Device With Breath Control (NCT04208984) | University of Utah | 2026-01-31 |
| The Use of Isocapnic Hyperventilation (iHV) for Treatment of Methanol Poisoned Patients (NCT06173817) | Oslo University Hospital | 2026-01-29 |
| This is an Open-Label Study to Assess the Safety and Efficacy of GC012F in Patients With Multiple Sclerosis (NCT07364487) | Huashan Hospital | 2026-01-26 |
| The Sequestration of Holistic Stress Management Techniques for Adults (NCT06098755) | Goddess Zena I. Jones | 2026-01-26 |
| Holistic Medicine Treatment of Uterine Fibroids-Adults (NCT07219381) | Virtual Tribunal Monastery | 2026-01-26 |
| VAPorized Administration of Bumetanide for Outpatient Relief in Heart Failure (NCT07375212) | Prisma Health-Upstate | 2026-01-21 |
| Testing Regional Anesthesia Techniques for Up and Early Discharge Following Knee Arthroplasty - A Feasibility Study (NCT06054750) | McMaster University | 2026-01-15 |
| A Study of Nipocalimab in Adult Participants With Active Lupus Nephritis (NCT04883619) | Janssen Research & Development, LLC | 2026-01-15 |
| Evaluation of the Ketogenic Diet to Improve Post Operative Cognitive Decline in Cardiac Surgery (NCT06480708) | University of Missouri-Columbia | 2026-01-15 |
| Direct Topical Lung T3 Treatment to Improve Outcome & Sequelae of COVID-19 Acute Respiratory Distress Syndrome (NCT04725110) | University of Minnesota | 2026-01-15 |
| Dopamine D3 Receptor Occupancy in Bipolar Depression (NCT05060549) | New York State Psychiatric Institute | 2026-01-06 |
| A Ph2 Study to Evaluate the Safety, Efficacy and Tolerability of HT-6184 and Semaglutide in Obese Participants With T2DM (NCT07172867) | Halia Therapeutics, Inc. | 2026-01-06 |
| Transverse Tibial Transport for Chronic Limb-Threatening Ischemia (CLTI) (NCT07175129) | University Hospitals Cleveland Medical Center | 2026-01-05 |
| Knee Prosthetic Joint Infection Antibiotic Elution (NCT06023238) | University of Pittsburgh | 2026-01-05 |
| AllogeneiC Expanded Human MSC Therapy in Patients Recovering From COVID-19 Acute Respiratory Distress Trial (NCT05491681) | BioCardia, Inc. | 2026-01-04 |