| A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement (NCT04543188) | Pfizer | 2021-01-08 |
| Study of Ulixertinib for Patients With Advanced Malignancies Harboring MEK or Atypical BRAF Alterations (NCT04488003) | BioMed Valley Discoveries, Inc | 2021-01-07 |
| Neurofeedback-EEG-VR System for Non-opioid Pain Therapy (NCT04551092) | Quantum Applied Science & Research, Inc. | 2021-01-07 |
| Futibatinib and Pembrolizumab Combination in the Treatment of Advanced or Metastatic Urothelial Carcinoma (NCT04601857) | Taiho Oncology, Inc. | 2021-01-07 |
| Infliximab and Intravenous Immunoglobulin Therapy in Treating Patients With Steroid-Refractory Pneumonitis (NCT04438382) | ECOG-ACRIN Cancer Research Group | 2021-01-07 |
| TXA in Revision Total Shoulder Arthroplasty (NCT04650698) | NYU Langone Health | 2021-01-07 |
| Self-Sampling for Human Papillomavirus (HPV) at Well Women Appointments (NCT04591977) | Milton S. Hershey Medical Center | 2021-01-07 |
| A Trial Evaluating the Safety and Effects of an RNA Vaccine ARCT-021 in Healthy Adults (NCT04668339) | Arcturus Therapeutics, Inc. | 2021-01-07 |
| Trilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving FOLFOXIRI/Bevacizumab for Metastatic Colorectal Cancer (mCRC): (NCT04607668) | G1 Therapeutics, Inc. | 2021-01-06 |
| Accuracy of Rhythm Detection by a Wearable Smart Watch for Cardiac Arrhythmias (The WATCH-RHYTHM Study) (NCT04499807) | Kansas City Heart Rhythm Research Foundation | 2021-01-06 |
| A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease (NCT04619420) | Janssen Research & Development, LLC | 2021-01-06 |
| Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS) (NCT04502433) | Chiesi Farmaceutici S.p.A. | 2021-01-06 |
| Futibatinib Versus Gemcitabine-Cisplatin Chemotherapy as First-Line Treatment of Patients With Advanced Cholangiocarcinoma Harboring FGFR2 Gene Rearrangements (NCT04093362) | Taiho Oncology, Inc. | 2021-01-06 |
| Synthetic Metabolic and Genetic Networks for Medical Diagnosics (NCT04518072) | University Hospital, Montpellier | 2021-01-06 |
| Safety of SNK01 in Subjects With Alzheimer's Disease (ASK-AD) (NCT04678453) | NKGen Biotech, Inc. | 2021-01-06 |
| A Study to Investigate the Long-term Safety, Tolerability, and Efficacy of Rozanolixizumab in Study Participants With Persistent or Chronic Primary Immune Thrombocytopenia (ITP) (NCT04596995) | UCB Biopharma SRL | 2021-01-06 |
| Reliability and Reproducibility of the Eye Check Tonometer (NCT04639947) | Duke University | 2021-01-06 |
| Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases (NCT04610684) | Jeffrey Clarke | 2021-01-05 |
| Radiation Post-CAR T in Refractory Lymphoma (NCT04473937) | Massachusetts General Hospital | 2021-01-05 |
| Efprezimod Alfa (CD24Fc, MK-7110) for the Prevention of Acute Graft Versus Host Disease (GVHD) Following Myeloablative Hematopoietic Stem Cell Transplantation (HSCT) (MK-7110-005) (NCT04095858) | Oncoimmune, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2021-01-05 |
| Naltrexone Treatment for Prolonged Grief Disorder (PGD) (NCT04547985) | Weill Medical College of Cornell University | 2021-01-05 |
| Optimizing Recovery in Abdominoplasty (NCT04254692) | University of Wisconsin, Madison | 2021-01-05 |
| At-Home Infusion Using Bamlanivimab in Participants With Mild to Moderate COVID-19 (NCT04656691) | Daniel Griffin | 2021-01-04 |
| In-hospital Diabetes Management With Flash Glucose Monitoring (isCGM) - the INDIGO Study, Part A (NCT04650945) | University of Aarhus | 2021-01-04 |
| A Study to Evaluate the Safety and Tolerability of RO7296682 in Combination With Atezolizumab in Participants With Advanced Solid Tumors. (NCT04642365) | Hoffmann-La Roche | 2021-01-04 |
| In-hospital Diabetes Management With Flash Glucose Monitoring (isCGM) - the INDIGO Study, Part B (NCT04630925) | University of Aarhus | 2021-01-04 |
| Open Label Extension Study to Assess the Safety and Long-Term Immunogenicity of ARCT-021 (NCT04728347) | Arcturus Therapeutics, Inc. | 2021-01-04 |
| A Placebo-controlled Study of Volixibat in Subjects With Elevated Serum Bile Acids Associated With Intrahepatic Cholestasis of Pregnancy (OHANA) (NCT04718961) | Mirum Pharmaceuticals, Inc. | 2021-01-04 |
| Mechanisms of EPO-induced Hypertension (NCT03810911) | VA Office of Research and Development | 2021-01-04 |
| Efficacy and Mechanism of Action of Methenamine Hippurate (Hiprex™) in Women With Recurring Urinary Tract Infections. (NCT04709601) | University of Texas Southwestern Medical Center | 2021-01-04 |
| First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal Blindness (NCT04485858) | CorNeat Vision Ltd. | 2021-01-03 |
| A Phase I Study to Evaluate Safety and Pharmacokinetics of Escalating Single Doses and Multiple Doses of SP-8356 (NCT05574166) | Shin Poong Pharmaceutical Co. Ltd. | 2021-01-03 |
| The Effect of IV NSAID's and Corticosteroids on Dysphasia and Dysphonia Following ASDF (NCT04650893) | University of Nebraska | 2021-01-02 |
| Cranberry and Quillaja on Symptoms of Uncomplicated UTI (NCT04496726) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2021-01-01 |
| Anti-Epilepsy Medication Valproate Administered Via ICV Route and Catheters and Pumps for CSF Infusion (NCT04529954) | Cerebral Therapeutics LLC | 2021-01-01 |
| Mechanisms and Treatment of Post-amputation Neuropathic Pain (NCT04819503) | Oslo University Hospital | 2021-01-01 |
| Hyperbaric Oxygen and Outcome After Below Knee Amputations (NCT04717557) | Duke University | 2021-01-01 |
| Longitudinal One Year vs Single Day NRP Training. (NCT04572048) | Ahmed Moussa | 2021-01-01 |
| Computer-Assisted Fixation of Trochanteric Femur Fractures (NCT04528459) | Columbia University | 2021-01-01 |
| Blinatumomab Bridging Therapy for BALL (NCT04556084) | Michael Burke | 2021-01-01 |
| FLT3 Ligand, CD40 Agonist Antibody, and Stereotactic Radiotherapy (NCT04491084) | Albert Einstein College of Medicine | 2021-01-01 |
| Function and Composition of Regulatory B Cells in Participants With Glioblastoma (NCT04128774) | Amsterdam UMC, location VUmc | 2021-01-01 |
| CCM Blood Biomarker Validation Study (NCT05148663) | Texas Tech University Health Sciences Center, El Paso | 2021-01-01 |
| Efficacy of Bilateral Modified Catheter Antegrade Cerebral Perfusion in Acute Type A Aortic Dissection Surgery (NCT06943716) | China Medical University Hospital | 2021-01-01 |
| Near-Infrared Light Photobiomodulation Treatment for Retinal Vein Occlusion Macular Oedema (NCT04847869) | University of Sydney | 2021-01-01 |
| Use and Misuse of Domperidone in Parkinson's Disease in France - Observational (NCT04653584) | Assistance Publique - Hôpitaux de Paris | 2021-01-01 |
| Laser Dosage in MicroPulse TransScleral CycloPhotocoagulation (NCT04709679) | State University of New York at Buffalo | 2021-01-01 |
| Closure After Total Shoulder Arthroplasty: Prineo vs Dermabond (NCT03899753) | Montefiore Medical Center | 2020-12-31 |
| RAPA-501-Allo Therapy of COVID-19-ARDS (NCT04482699) | Rapa Therapeutics LLC | 2020-12-30 |
| Global Prevalence of ATTR-CM in Participants With HFpEF (NCT04424914) | Pfizer | 2020-12-30 |
| A Study of FT-7051 in Men With MCRPC (NCT04575766) | Novo Nordisk A/S | 2020-12-30 |
| CORVax12: SARS-CoV-2 Spike (S) Protein Plasmid DNA Vaccine Trial for COVID-19 (SARS-CoV-2) (NCT04627675) | Providence Health & Services | 2020-12-30 |
| IMCY-0098 Proof of ACtion in Type 1 Diabetes (IMPACT Study) (NCT04524949) | Imcyse SA | 2020-12-29 |
| A 12-Month Observational Prospective Cohort Study to Analyze Cardiometabolic Profile Changes to Switch to Lurasidone in Patients With Schizophrenia. RESPECT Study. (NCT04742413) | Angelini Farmacéutica | 2020-12-29 |
| A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degeneration (NCT04684394) | Gemini Therapeutics, Inc. | 2020-12-29 |
| Patient Reported Outcomes Following Targeted Muscle Reinnervation (NCT04658368) | University of Wisconsin, Madison | 2020-12-29 |
| A Study of TP-0184 to Treat Anemia in Adults With IPSS-R Low or Intermediate Risk MDS (NCT04623996) | Sumitomo Pharma America, Inc. | 2020-12-28 |
| Use of the DJO Brace With the Motion Intelligence Platform in the Postoperative Total Knee Arthroplasty Patient (NCT04655703) | Northwell Health | 2020-12-28 |
| Nutritional Intervention and Outcomes in Elderly After Hip Fracture Surgery (NCT04451538) | Peking University First Hospital | 2020-12-28 |
| Operative vs Non-Operative Management of Acute Appendicitis and Acute Cholecystitis in COVID-19 Positive Patients (NCT04748120) | The Cleveland Clinic | 2020-12-28 |
| Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting in Gynecologic Oncology Patients (NCT04503668) | University of Michigan Rogel Cancer Center | 2020-12-28 |
| A Study Evaluating the Effects of GLPG3970 Given as Oral Treatment for 12 Weeks in Adults With Systemic Lupus Erythematosus (NCT04700267) | Lakefront Biotherapeutics NV | 2020-12-28 |
| Perioperative Therapy for Hepatocellular Carcinoma (NCT04653389) | Zhejiang University | 2020-12-26 |
| HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB) (NCT04684914) | Altimmune, Inc. | 2020-12-26 |
| Efficacy, Safety, and Tolerability of ATM-AVI in the Treatment of Serious Infection Due to MBL-producing Gram-negative Bacteria (NCT03580044) | Pfizer | 2020-12-25 |
| Liposomal Mitoxantrone Hydrochloride Injection,Cyclophosphamide, Vincristine and Prednisone in the Treatment of PTCL (NCT04548700) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2020-12-24 |
| A Study on the Safety and Effectiveness of IBI318 Combined With Conventional TACE (cTACE) as a Perioperative Treatment for Potentially Resected Hepatocellular Carcinoma (NCT04635527) | Innovent Biologics (Suzhou) Co. Ltd. | 2020-12-24 |
| Work And Vocational advicE Study - Effectiveness of Adding a Brief Vocational Support Intervention to Usual Primary Care (NCT04543097) | Keele University | 2020-12-23 |
| Colchicine for the Treatment of Cardiac Injury in Hospitalized Patients With COVID-19 (COLHEART-19) (NCT04762771) | Baptist Health South Florida | 2020-12-23 |
| The WavelinQ™ Arterio-Venous Endovascular Fistula: A Global, Post-Market Investigation (NCT04626427) | C. R. Bard | 2020-12-23 |
| Treatment of Angiotensin Converting Enzyme Inhibitor-induced Angioedema (NCT04679311) | Washington University School of Medicine | 2020-12-22 |
| A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB) (NCT04441788) | Ionis Pharmaceuticals, Inc. | 2020-12-22 |
| Reduce Intensity Conditioning Donor Stem Cell Transplant for the Treatment of Relapsed Multiple Myeloma (NCT04205240) | Srinivas Devarakonda | 2020-12-22 |
| Application of Convalescent Plasma in the Treatment of SARS CoV-2 Disease (COVID-19) With Evaluation of Therapy Effectiveness (NCT04642014) | Wroclaw Medical University | 2020-12-22 |
| A Study of Darvadstrocel in Adults With Crohn's Disease and Complex Perianal Fistula (NCT04118088) | Takeda | 2020-12-22 |
| A Study of TAS1553 in Subjects With Relapsed or Refractory Acute Myeloid Leukemia (AML) and Other Myeloid Neoplasms (NCT04637009) | Astex Pharmaceuticals, Inc. | 2020-12-21 |
| A Multi-center, International Prospective Follow up Study (NCT04579913) | Medi-Tate Ltd. | 2020-12-21 |
| Master Protocol to Assess Safety and Dose of First Time in Human Next Generation Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Advanced Solid Tumors (NCT04526509) | Adaptimmune | 2020-12-21 |
| Pharmacokinetics, Safety, Tolerability and Efficacy of a New Artemether-lumefantrine Dispersible Tablet in Infants and Neonates <5 kg Body Weight With Acute Uncomplicated Plasmodium Falciparum Malaria (NCT04300309) | Novartis Pharmaceuticals | 2020-12-21 |
| Study of Melflufen (Melphalan Flufenamide) in Combination With Daratumumab in Relapsed-Refractory Multiple Myeloma (NCT04649060) | Oncopeptides AB | 2020-12-21 |
| Characterization of Corneal Epithelial Changes in Participants Treated With Belantamab Mafodotin (NCT04549363) | GlaxoSmithKline | 2020-12-21 |
| Ivosidenib and Combination Chemotherapy for the Treatment of IDH1 Mutant Relapsed or Refractory Acute Myeloid Leukemia (NCT04250051) | Northwestern University | 2020-12-21 |
| Efficacy of the Sit to Stand Test in the Decision to Hospitalize a Patient Consulting the Emergency Dept for COVID 19 (NCT04730661) | University Hospital, Rouen | 2020-12-21 |
| Study of GSK3845097 in Previously Treated Participants With Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma (NCT05943990) | Adaptimmune | 2020-12-21 |
| InterLeukin-7 to Improve Clinical Outcomes in Lymphopenic Patients With COVID-19 Infection ( ILIAD-7-US-O ) (NCT04426201) | Revimmune | 2020-12-20 |
| Russian Registry of Patients With nAMD (NCT04935411) | Novartis Pharmaceuticals | 2020-12-20 |
| Tamoxifen Therapy for Myotubular Myopathy (NCT04915846) | James Dowling | 2020-12-18 |
| A Long-Term Safety Study of BCX9930 in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) (NCT04702568) | BioCryst Pharmaceuticals | 2020-12-18 |
| Mouth Rinses for Inactivation of COVID-19 (NCT04584684) | University of North Carolina, Chapel Hill | 2020-12-18 |
| CHF6563 in Babies With Neonatal Opioid Withdrawal Syndrome (NCT04104646) | Chiesi Farmaceutici S.p.A. | 2020-12-18 |
| Health Literacy in Understanding Radiation Therapy Information in Patients Undergoing Definitive Radiation Therapy (NCT04927559) | University of Southern California | 2020-12-18 |
| Rehabilitation with Personalized Strategies According to Muscle Volume Before Knee Arthroplasty (NCT04318197) | University Hospital, Brest | 2020-12-18 |
| First-in-Human Study of INT-1B3 in Patients With Advanced Solid Tumors (NCT04675996) | InteRNA | 2020-12-18 |
| Endoscopic Strip Craniectomy for Treatment of Sagittal Craniosynostosis (NCT04721769) | Baylor College of Medicine | 2020-12-18 |
| A Study of Brexanolone for Acute Respiratory Distress Syndrome (ARDS) Due to Coronavirus Disease 2019 (COVID-19) (NCT04537806) | Sage Therapeutics | 2020-12-18 |
| Varenicline For Nicotine Vaping Cessation In Non Smoker Vaper Adolescents (NCT04602494) | Massachusetts General Hospital | 2020-12-18 |
| Long-term Follow-up Durability (Efficacy) Study of EN3835 for the Treatment of AC of the Shoulder (Frozen Shoulder) (NCT04680156) | Endo USA Inc., a Keenova Therapeutics Company | 2020-12-17 |
| To Evaluate the Safety and Efficacy of Microwave Ablation Therapy in Patients With Primary Liver Cancer (NCT04520906) | Suzhou Hengruihongyuan Medical Technology Co. LTD | 2020-12-17 |
| User Satisfaction When Catheterizing With Hydrophilic Urinary Catheters From a More Sustainable Manufacturing Process. (NCT04703413) | Wellspect HealthCare | 2020-12-17 |
| Vactosertib in Combination with Pembrolizumab for PD-L1 Positive Non-small Cell Lung Cancer (NSCLC) Subjects (NCT04515979) | MedPacto, Inc. | 2020-12-17 |