| Safety, Immunogenicity and ex Vivo Efficacy of Pfs25-IMX313/Matrix-M in Healthy Volunteers in Bagamoyo, Tanzania. (NCT04271306) | University of Oxford | 2021-05-25 |
| To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313) (NCT04551066) | Incyte Corporation | 2021-05-24 |
| A Disease-based Treatment Study for Diagnosed Osteoarthritis Utilizing Adipose-derived Regenerative Cells (NCT04405297) | Sanford Health | 2021-05-24 |
| A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors (NCT04644315) | Hoffmann-La Roche | 2021-05-24 |
| A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG) (NCT04771897) | Bexion Pharmaceuticals, Inc. | 2021-05-24 |
| Recombinant Hyperimmune Polyclonal Antibody (GIGA-2050) in COVID-19 Patients (NCT04883138) | GigaGen, Inc. | 2021-05-24 |
| A Study of Ociperlimab With Tislelizumab Compared to Pembrolizumab in Participants With Untreated Lung Cancer (NCT04746924) | BeiGene | 2021-05-24 |
| A Study to Evaluate ASP0367 in Participants With Primary Mitochondrial Myopathy (NCT04641962) | Astellas Pharma Inc | 2021-05-24 |
| Continuous Erector Spinae Plane Blocks for Rib Fractures (NCT04558281) | University of California, San Diego | 2021-05-23 |
| Study to Assess Adverse Events, Change in Disease Activity and How Oral ABBV-4083 Capsules When Given Alone or In Combination With Albendazole Capsules Moves in The Body of Adult Participants With Onchocerca Volvulus Infection (NCT04913610) | AbbVie | 2021-05-22 |
| The IRMI-FMT Trial (NCT04577729) | Medical University of Graz | 2021-05-21 |
| HM242-Gel vs Comparator (NCT04902651) | B. Braun Ltd. Centre of Excellence Infection Control | 2021-05-21 |
| Study of Disulfiram and Copper Gluconate in Patients With Treatment-Refractory Multiple Myeloma (NCT04521335) | University of Utah | 2021-05-21 |
| EpiRetinal Membrane Peeling and Internal Limiting Membrane (NCT04802265) | University Hospital, Clermont-Ferrand | 2021-05-21 |
| Alexa, What is Eliquis and Xarelto? (NCT04790773) | Cedars-Sinai Medical Center | 2021-05-21 |
| Efficacy of Fluticasone Propionate Associated With Salmeterol Using Inhalation Chamber Versus Placebo to Improve the Respiratory Function in Children Over Six Years of Age Who Underwent Allogeneic Hematopoietic Stem Cell Transplantation With a Decline of FEV1 ≥10% From Pre Transplantation (NCT04655508) | Assistance Publique - Hôpitaux de Paris | 2021-05-21 |
| Characterization of Innate Immune System in Patients With Luminal Advanced Breast Cancer (NCT04370522) | Spanish Breast Cancer Research Group | 2021-05-21 |
| Impact of Catch-up HPV Vaccination (NCT05462249) | University Hospital, Brest | 2021-05-21 |
| Clinical Study of Moisture Sensor Dressing Used for Exuding Wounds (NCT04890769) | Fredrik Iredahl | 2021-05-21 |
| Diagnostic Performance of PSMA PET/CT for Pre-operative Lymph Node Assessment in Intermediate and High-risk Non-metastasic Prostate Cancer (PREOP-PSMA ). (NCT04745871) | University Hospital, Brest | 2021-05-20 |
| Nebulized Heparin for COVID19-associated Acute Respiratory Failure (NCT04842292) | Brittany Bissell | 2021-05-20 |
| Efficacy and Safety of MK-1942 When Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression (TRD) (MK-1942-006) (NCT04663321) | Merck Sharp & Dohme LLC | 2021-05-20 |
| Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Maintenance Treatment (Trastuzumab and Pertuzumab) After Initial Chemotherapy in a Phase Ib/II Trial for Advanced HER2 Positive Breast Cancer (NCT04108858) | National Cancer Institute (NCI) | 2021-05-20 |
| A Clinical Study Preliminary Efficacy of LM-061 Tablet in Subjects With Advanced Tumours (NCT04882176) | LaNova Medicines Limited | 2021-05-20 |
| Pharmacokinetics and Pharmacogenomics of Ribociclib in Race-based Cohorts (NCT04657679) | Georgetown University | 2021-05-20 |
| A Study Evaluating the Safety, Tolerability, and Effect on Microvascular Obstruction of Intravenous Temanogrel in Adult Participants Undergoing Percutaneous Coronary Intervention (NCT04848220) | Pfizer | 2021-05-20 |
| Prospective Comparison of Revolve™ and AuraGen 123 With AuraClens™ in Autologous Fat Grafting to the Breast (NCT04906811) | AuraGen Aesthetics LLC | 2021-05-20 |
| A Ph1/2 Study of EMB-06 in Participants With Relapsed or Refractory Myeloma (NCT04735575) | Shanghai EpimAb Biotherapeutics Co., Ltd. | 2021-05-20 |
| Flotetuzumab for Relapsed Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Following Allogeneic Hematopoietic Cell Transplantation (Allo-HCT) (NCT04582864) | Washington University School of Medicine | 2021-05-20 |
| New Horizons for the Treatment of Cardiomyopathy in Children (NCT04893629) | Damascus University | 2021-05-20 |
| The Effect of Cetirizine HCl on Exercise-induced Arterial Hypoxemia in Highly-trained Swimmers (NCT05095311) | Indiana University | 2021-05-19 |
| Assessment of Adjunctive Cannabidiol Oral Solution (GWP42003-P) in Children With Tuberous Sclerosis Complex (TSC), Dravet Syndrome (DS), or Lennox-Gastaut Syndrome (LGS) Who Experience Inadequately-controlled Seizures (NCT04485104) | Jazz Pharmaceuticals | 2021-05-19 |
| An Explorative Study of Treatment of Contact Dermatitis Due to DiabetesDevices (NCT04909983) | Copenhagen University Hospital at Herlev | 2021-05-19 |
| ALY688-SR in Generally Healthy Overweight or Obese Adults (NCT04855565) | Allysta Pharmaceutical | 2021-05-19 |
| Safety, Tolerability and the Pharmacokinetics of Ridinilazole in Adolescent Subjects (NCT04802837) | Summit Therapeutics | 2021-05-19 |
| Observational Study of Fostamatinib as Second Line Therapy in Adult Patients With Immune Thrombocytopenia (ITP) and Insufficient Response to a Prior Therapy (NCT04904276) | Rigel Pharmaceuticals | 2021-05-18 |
| Airway Clearance for Pediatric and Adult Cystic Fibrosis Patients Using a Portable Intra-Pulmonary Percussion Device (NCT04743206) | University of Florida | 2021-05-18 |
| A Study in Preterm Neonates With Respiratory Distress Syndrome (RDS) Comparing CUROSURF® Administration Through Less Invasive Surfactant Administration (LISA) and Conventional Administration (NCT02772081) | Chiesi Farmaceutici S.p.A. | 2021-05-18 |
| Inhaled Aviptadil for the Treatment of COVID-19 in Patients at High Risk for ARDS (NCT04536350) | Prof. Dr. Jörg Leuppi | 2021-05-18 |
| Nitrous Oxide for Pain Management During In-Office Gynecology Procedures (NCT06661005) | University of Arizona | 2021-05-17 |
| Setting up a Website in Paediatric Surgery at the Rouen University Hospital for Parents and Children to Better Understand the Postoperative Prescription of Painkillers. (NCT04564248) | University Hospital, Rouen | 2021-05-17 |
| Gastrointestinal STRING Test With Oral Immunotherapy (NCT04943744) | Stanford University | 2021-05-17 |
| PROUD Study - Preventing Opioid Use Disorders (NCT04766996) | Emory University | 2021-05-17 |
| A Multi-Center Study of a SCD for Immunomodulatory Dysregulation in Pediatric AKI (NCT04869787) | Children's Hospital Medical Center, Cincinnati | 2021-05-17 |
| Study To Assess The Safety And Efficacy Of The Tempsure Flexsure Applicators For Abdominal Wrinkles (NCT04930705) | Cynosure, Inc. | 2021-05-17 |
| Study of Coagulation Factor VIIa Marzeptacog Alfa (Activated) in Subjects With Inherited Bleeding Disorders (NCT04548791) | Catalyst Biosciences | 2021-05-17 |
| Registrational Trial to Compare Effectiveness of Two Digital Software Medical Devices as Adjunctive Oncology Treatment (NCT04862195) | Blue Note Therapeutics | 2021-05-15 |
| Effect of Dronedarone on Atrial Fibrosis Progression and Atrial Fibrillation Recurrence (NCT04704050) | Tulane University School of Medicine | 2021-05-15 |
| Comparing CHG I.V. Securement Dressing With Transparent Dressing for Evaluation of Antimicrobial Efficacy (NCT04906512) | Solventum US LLC | 2021-05-14 |
| Lifestyle and Non-motor Symptom Management in Parkinson's Disease (NCT04837976) | Oxford Brookes University | 2021-05-14 |
| Evaluate the Effect of Tirazamine on Primary Liver Cancer. (NCT06848556) | Zhejiang Raygene Pharmaceuticals Co., Ltd | 2021-05-14 |
| Evaluation of the Effect of Laser Acupuncture on Taxane Acute Pain Syndrome Patients (NCT04872556) | Chang Gung Memorial Hospital | 2021-05-13 |
| Study of Safety, Tolerability, and Pharmacokinetics of INE963 in Healthy Participants (NCT04896632) | Novartis Pharmaceuticals | 2021-05-13 |
| A Multiple Ascending Dose Study of ACN00177 (Pegtarviliase) in Subjects With CBS Deficiency (NCT05154890) | Aeglea Biotherapeutics | 2021-05-13 |
| RC18 in Patients With Relapsing Remitting Multiple Sclerosis：a Phase II Trial (NCT04625153) | RemeGen Co., Ltd. | 2021-05-13 |
| Effect of Chitosan-N-acetylcysteine on Subjective Pain Sensation in Corneal Abrasion (NCT05049642) | Vienna Institute for Research in Ocular Surgery | 2021-05-12 |
| Evaluation of Daily Hemodialysis With Low Dialysate Flux in Unscheduled Patients With Kidney Injury Admitted to Hemodialysis (NCT03963960) | Centre Hospitalier Departemental Vendee | 2021-05-12 |
| Efficacy of Different Treatment Regimens With Chitosan-N- Acetylcysteine in Moderate-to-severe Dry Eye Disease (NCT05053789) | Vienna Institute for Research in Ocular Surgery | 2021-05-12 |
| Impact of an Information Assistance Application in Addition to a Traditional Anesthesia Consultation on Preoperative Anxiety in Pediatrics: Prospective Randomized Trial (NCT05401617) | University Hospital, Rouen | 2021-05-12 |
| Moisture Management Liner At-Home Evaluation (NCT05124873) | Liberating Technologies, Inc. | 2021-05-12 |
| Effect of Chitosan-N-Acetylcysteine on IOL-power Prior to Cataract Surgery (NCT05049629) | Vienna Institute for Research in Ocular Surgery | 2021-05-12 |
| Immunological Response to COVID-19 Vaccine in Patients With Autoimmune and Inflammatory Diseases Treated With Immunosuppressants and/or Biologics (NCT04870411) | Assistance Publique - Hôpitaux de Paris | 2021-05-12 |
| A Study to Evaluate the Safety and Efficacy of Paltusotine for the Treatment of Acromegaly (NCT04837040) | Crinetics Pharmaceuticals Inc. | 2021-05-12 |
| TisaGenlecleucel in Elderly Patients With First-Relapsed or Primary Refractory Aggressive B-cell Non-Hodgkin Lymphoma (NCT04161118) | University of Cologne | 2021-05-12 |
| Safety and Efficacy of Selinexor in Combination With Pembrolizumab in Recurrent Advanced Melanoma (NCT04768881) | Karyopharm Therapeutics Inc | 2021-05-12 |
| Docetaxel Chemotherapy and Pembrolizumab Plus Interleukin-12 Gene Therapy in Triple Negative Breast Cancer (NCT04095689) | The Methodist Hospital Research Institute | 2021-05-12 |
| A Safety and Efficacy Study of LYS-GM101 Gene Therapy in Patients With GM1 Gangliosidosis (NCT04273269) | LYSOGENE | 2021-05-11 |
| FHD-286 in Subjects With Metastatic Uveal Melanoma (NCT04879017) | Foghorn Therapeutics Inc. | 2021-05-11 |
| Azole-echinocandin Combination Therapy for Invasive Aspergillosis (NCT04876716) | Erasmus Medical Center | 2021-05-11 |
| Non-interventional Study Describing Healthcare Resource Utilisation and Clinical Outcomes Associated With VNS Therapy in UK. (NCT04779814) | LivaNova | 2021-05-11 |
| Severe Head Trauma: Coagulation and CT-Scan Aggravation. (NCT06246500) | Centre Hospitalier Annecy Genevois | 2021-05-11 |
| A Dose Finding, Efficacy and Safety Study of Ensovibep (MP0420) in Ambulatory Adult Patients With Symptomatic COVID-19 (NCT04828161) | Novartis Pharmaceuticals | 2021-05-10 |
| Safety and Efficacy of XmAb18087 ± Pembrolizumab in Advanced Merkel Cell Carcinoma or Extensive-stage Small Cell Lung Cancer (NCT04590781) | Xencor, Inc. | 2021-05-10 |
| Observational Study to Evaluate Fluid Resolution and Effectiveness of Brolucizumab for nAMD in Portugal (NCT04764656) | Novartis Pharmaceuticals | 2021-05-10 |
| Bone Loss in Melanoma Survivors Receiving Immunotherapy (NCT04516122) | M.D. Anderson Cancer Center | 2021-05-10 |
| TRAIN Your Sleep; Treating Adolescent Insomnia With Cognitive Behavioral Therapy for Insomnia (CBT-I) (NCT04920630) | Indiana University | 2021-05-10 |
| RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors and Melanoma (NCT04762225) | Repertoire Immune Medicines | 2021-05-10 |
| A Study of Abemaciclib (LY2835219) Plus Hormone Therapy in Participants With Early Breast Cancer (NCT04752332) | Eli Lilly and Company | 2021-05-10 |
| Compression Headphone Study (NCT04882709) | Sonova AG | 2021-05-10 |
| Specialized Pacing for Patients With Congenital Heart Disease (NCT03361189) | University of California, Los Angeles | 2021-05-09 |
| A Trial of Tigilanol Tiglate in Combination With Pembrolizumab in Stage IIIB to IV M1c-melanoma (NCT04834973) | QBiotics Group Limited | 2021-05-07 |
| Optimisation of Potential Dental Implant Sites Protection for Rehabilitation in Patients With Head and Neck Cancer: Impact of Virtual Implants Visualisation on Dosimetry (OPPIDOM) (NCT04801472) | Institut de cancérologie Strasbourg Europe | 2021-05-07 |
| Review of Post-Study Clinical Endoscopy Reports in Follow Up to MAY2016-07-01 (NCT04674228) | National Cancer Institute (NCI) | 2021-05-07 |
| A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infection (NCT04820686) | Assembly Biosciences | 2021-05-07 |
| Validation of Quantitative Myocardial Tissue Characterization Through Non-gated CT (NCT04880317) | IRCCS Policlinico S. Donato | 2021-05-07 |
| Phase 2b Study of GC4711 in Combination With SBRT for Nonmetastatic Pancreatic Cancer (NCT04698915) | Galera Therapeutics, Inc. | 2021-05-07 |
| Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Diabetic Peripheral Neuropathic Pain (NCT04707157) | Eli Lilly and Company | 2021-05-06 |
| Efficacy and Safety of Efavaleukin Alfa in Subjects With Active Systemic Lupus Erythematosus (NCT04680637) | Amgen | 2021-05-06 |
| CB-103 Plus NSAI In Luminal Advanced Breast Cancer (NCT04714619) | MedSIR | 2021-05-06 |
| Evaluation of All'InCath in Peripheral Vasculature Percutaneous Transluminal Angioplasty. (NCT05153421) | NexStep Medical | 2021-05-06 |
| Cardiovascular Safety Study of Tipifarnib in Patients With Advanced Solid Malignancies (NCT04865159) | Kura Oncology, Inc. | 2021-05-06 |
| Study of LM-061 in Subjects in Advanced Tumors (NCT04737122) | LaNova Medicines Limited | 2021-05-06 |
| Mothers' Own Milk Optimization for Preterm Infants Project (MoMO PIP) Pilot Study (NCT04629534) | Medical University of South Carolina | 2021-05-06 |
| Mindfulness Practice in Pregnancy As an Intervention to Decrease Prenatal Stress During the COVID-19 Pandemic (NCT05087329) | University of Pennsylvania | 2021-05-05 |
| Comparison of Levothyroxine Formulation in Hypothyroid Patients With Enteral Feeding (NCT04878614) | University of California, Los Angeles | 2021-05-05 |
| Efficacy and Safety of Oral BT-11 in Moderate to Severe Crohn's Disease (NCT03870334) | NImmune Biopharma | 2021-05-05 |
| Efficacy and Safety of VB119 in Subjects With Membranous Nephropathy (NCT04652570) | Tenet Medicines | 2021-05-05 |
| Radiation Therapy on Pelvic Floor Disorders in Women (NCT04623515) | Wake Forest University Health Sciences | 2021-05-05 |
| Efficacy and Safety of Alflorex Bei Reizdarm in Patients With Irritable Bowel Syndrome (NCT04859075) | Medice Arzneimittel Pütter GmbH & Co KG | 2021-05-05 |
| This SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols. (NCT05061940) | Repertoire Immune Medicines | 2021-05-05 |