| Safety and Tolerability Study of Lu AG06466 in Healthy Young Japanese and Caucasian Participants (NCT05177029) | H. Lundbeck A/S | 2021-11-26 |
| Effect of Ranibizumab Versus Bevacizumab on the Macular Perfusion in Diabetic Macular Edema (NCT04991350) | Cairo University | 2021-11-26 |
| Clinical Trial to Assess the Safety and Efficacy of Investigational Product in Patients Due to Hypospadias Treatment Failure (NCT05093166) | Holostem s.r.l. | 2021-11-26 |
| Study to Assess the Efficacy and Safety of Favipiravir-HU (NCT04940871) | University of Pecs | 2021-11-25 |
| Two Seawater-based Formulations for Relief of Nasal Congestion in Paediatric Subjects (NCT05244148) | Church & Dwight Company, Inc. | 2021-11-25 |
| An Experimental Medicine Clinical Study to Compare Peripheral Immune System From Subjects Without Cancer Diagnosis and Patients With Solid Tumours. (NCT05133128) | Servier | 2021-11-25 |
| The Effect of D-serine as add-on Therapy in Recent-onset Psychosis (NCT04140773) | Dragos Inta | 2021-11-25 |
| Descartes-25 in Relapsed/Refractory Multiple Myeloma (NCT05113342) | Cartesian Therapeutics | 2021-11-25 |
| Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis (NCT05177107) | Adaptive Phage Therapeutics, Inc. | 2021-11-24 |
| Epidemiology of Injuries During Crossfit Practice (NCT05199220) | Centre Hospitalier Universitaire de la Réunion | 2021-11-24 |
| The Efficacy and Safety of Cobitolimod in Participants With Moderate to Severe Active Left-Sided Ulcerative Colitis (NCT04985968) | InDex Pharmaceuticals | 2021-11-24 |
| Curvafix® Intramedullary System for Fixation of Pelvic and Acetabular Fractures, A Post Market Evaluation (NCT05606042) | CurvaFix, Inc. | 2021-11-24 |
| Entospletinib Plus Intensive Induction/Consolidation Chemotherapy in Newly Diagnosed NPM1-mutated AML (NCT05020665) | Kronos Bio | 2021-11-24 |
| Recognizing Pain Intensity in Alzheimer's Disease (NCT04614532) | Centre Hospitalier Universitaire de Saint Etienne | 2021-11-24 |
| A Randomized, Double-blinded, Clinical, Placebo-controlled Trial on the Effects of Therapy With Letrozole and hUman Choriongonadotropin in Male Hypogonadism Induced by Illicit Use of Anabolic Androgenic Steroids- The LUCAS Trial (NCT05205837) | Rigshospitalet, Denmark | 2021-11-24 |
| Effect of Guselkumab on Cardiovascular Risk Surrogate Markers in Participants With Moderate to Severe Plaque Psoriasis (NCT05125679) | Janssen-Cilag Ltd. | 2021-11-23 |
| Exploratory Study to Evaluate the Efficacy of the Cosmetic Product RV3895A on Re-epidermised Scars Following Burns and Surgical Stitches in Adults, Adolescents and Children Over a 6-month Follow-up Period (NCT07020507) | Pierre Fabre Dermo Cosmetique | 2021-11-23 |
| Simplified IMmunosuppressive Protocol Utilizing Low Dose EnvarsusXR (NCT04773392) | University of Southern California | 2021-11-23 |
| Neurolens Convergence Insufficiency Study (NCT05087563) | Neurolens Inc. | 2021-11-22 |
| Steady Feet: Proof of Value (NCT04801316) | Changi General Hospital | 2021-11-22 |
| AZithromycin Therapy in Preschoolers With a Severe Wheezing Episode Diagnosed at the Emergency Department (NCT04669288) | University of Arizona | 2021-11-22 |
| Biomarker Research Study for Patients With FGFR-Mutant Bladder Cancer Receiving Erdafitinib (NCT05052372) | xCures | 2021-11-21 |
| A Lithium-Based Medication to Improve Neurological Outcomes After Surgical Carotid Reconstruction (NCT05126238) | Negovsky Reanimatology Research Institute | 2021-11-20 |
| Nitric Oxide Nasal Spray (NONS) as Prevention for Treatment of Individuals at Risk of Exposure to COVID-19 Infection (NCT05109611) | Sanotize Research and Development corp. | 2021-11-20 |
| Brolucizumab Treatment Experience Study of Patients With nAMD in UK Routine Clinical Practice (NCT05112835) | Novartis Pharmaceuticals | 2021-11-19 |
| Ravulizumab Versus Placebo in Adult Participants With Dermatomyositis (NCT04999020) | Alexion Pharmaceuticals, Inc. | 2021-11-19 |
| Patient Perception of MultiPulse Therapy™ (MPT™) (NCT04939584) | Cardialen, Inc. | 2021-11-19 |
| Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing Cancers (NCT05109442) | Affimed GmbH | 2021-11-19 |
| Swiss Study of the Impact of Mayzent on SPMS Patients in a Long-term Non-interventional Study (NCT04895202) | Novartis Pharmaceuticals | 2021-11-19 |
| An Observational Study of Aducanumab-avwa in Participants With Alzheimer's Disease in the US (NCT05097131) | Biogen | 2021-11-18 |
| Dexmedetomidine Supplemented Analgesia and Delirium After Hip Fracture Surgery (NCT04955249) | Peking University First Hospital | 2021-11-18 |
| A Trial to Evaluate the Efficacy and Safety of Different Doses of KVD824 for Prophylactic Treatment of HAE Type I or II (NCT05055258) | KalVista Pharmaceuticals, Ltd. | 2021-11-18 |
| Simufilam 50 mg or 100 mg for Mild-to-Moderate Alzheimer's Disease (NCT05026177) | Cassava Sciences, Inc. | 2021-11-18 |
| A Study of Rilematovir (JNJ-53718678) in Adult Outpatients With Respiratory Syncytial Virus (RSV) Infection (NCT04978337) | Janssen Research & Development, LLC | 2021-11-17 |
| Study to Evaluate the Efficacy of Uproleselan in Combination With Chemotherapy in Chinese Patients With R/R AML (NCT05054543) | Apollomics Inc. | 2021-11-17 |
| Prevention of Maternal-fetal Cytomegalovirus Transmission After Primary Maternal Infection, GW ≤ 14 (PreCyssion) (NCT05170269) | Biotest | 2021-11-17 |
| A Study With TEPEZZA in Patients With Diffuse Cutaneous Systemic Sclerosis (dcSSc) (NCT04478994) | Amgen | 2021-11-17 |
| Primary Hyperparathyroidism and Gut Microbiota (NCT04948671) | Centre Hospitalier Universitaire Vaudois | 2021-11-17 |
| Low Carbohydrate Small Intestine Study (NCT04976686) | Insel Gruppe AG, University Hospital Bern | 2021-11-17 |
| Hypotension Prediction Index (HPI) SMART-BP Trial (NCT05105477) | Edwards Lifesciences | 2021-11-17 |
| Radiofrequency Ablation Versus I-131 for Solitary Autonomous Thyroid Nodules (NCT05142904) | Rijnstate Hospital | 2021-11-17 |
| A Pilot Study to Determine the Feasibility, Acceptance, and Effectiveness of In-vitro Maturation in Patients Without IVF Coverage (NCT05793931) | Northwestern University | 2021-11-16 |
| Study of Efficacy and Safety of Ligelizumab in Adolescents and Adults With Chronic Inducible Urticaria Who Remain Symptomatic Despite Treatment With H1- Antihistamines (NCT05024058) | Novartis Pharmaceuticals | 2021-11-16 |
| A Study to Assess Adverse Events and Disease Activity With Cedirogant (ABBV-157) in Adult Participants With Moderate to Severe Psoriasis (NCT05044234) | AbbVie | 2021-11-16 |
| A Study Of ¹²⁹XE MRI To Assess Disease Progression In Patients With COPD Treated With Or Without Azithromycin And Standard-of-Care Medications (NCT04353661) | Genentech, Inc. | 2021-11-16 |
| Process-Based Therapy in an Outpatient Setting (NCT05105568) | Boston University Charles River Campus | 2021-11-16 |
| Study of Intravenous COVI-MSC for Treatment of COVID-19-Induced Acute Respiratory Distress (NCT04903327) | Sorrento Therapeutics, Inc. | 2021-11-16 |
| Subcuticular Absorbable Staples Versus Conventional Skin Closure in Women Undergoing Cesarean Delivery (NCT05112640) | The University of Texas Medical Branch, Galveston | 2021-11-16 |
| Function, Pain, and Alignment Following Knee Replacement for the Treatment of Osteoarthritis (NCT05490186) | North York General Hospital | 2021-11-16 |
| Tusamitamab Ravtansine (SAR408701) in Combination With Ramucirumab in Pretreated Participants With Gastric Cancer (NCT05071053) | Sanofi | 2021-11-16 |
| A Prospective International Multicenter Clinical Trial for Eyes With Relapsed Retinoblastoma (NCT04455139) | Prof. Beck Popovic Maja | 2021-11-15 |
| Efficacy of a Cognitive - Affective - Addictive Based Intervention to Decrease Food Craving in Obese Patients. (NCT04338178) | University Hospital, Bordeaux | 2021-11-15 |
| Immune Response After SARS-CoV-2 (COVID-19) Vaccination in a Context of Non-Hodgkin Lymphoma (NCT05050461) | Versailles Hospital | 2021-11-15 |
| Echinaforce COVID-19 Shedding Study (NCT04999098) | A. Vogel AG | 2021-11-15 |
| Cromolyn Sodium for Treatment of COVID-19 Pneumonia (NCT05077917) | Texas Tech University Health Sciences Center, El Paso | 2021-11-15 |
| EffiCacy, Safety and ToLErability of a Novel Ocular ANtiseptic for Ocular Use (CLEAN) (NCT05127525) | iRenix Medical, Inc. | 2021-11-15 |
| Human ECM Implanted Within Microfracture Interstices & the Cartilage Defect in the Knee to Regenerate Hyaline Cartilage (NCT05082831) | Histogen | 2021-11-15 |
| A Trial to Evaluate the Efficacy and Safety of PQ912 in Patients With Early AD (NCT03919162) | Vivoryon Therapeutics N.V. | 2021-11-15 |
| NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLC (NCT04984811) | NeoImmuneTech | 2021-11-15 |
| Study of NIS793 and Other Novel Investigational Combinations With SOC Anti-cancer Therapy for the 2L Treatment of mCRC (NCT04952753) | Novartis Pharmaceuticals | 2021-11-15 |
| Tinzaparin Lead-In to Prevent the Post-Thrombotic Syndrome (NCT04794569) | Sunnybrook Health Sciences Centre | 2021-11-15 |
| Automated Stereognosis to Treat Loss of Tactile Function After Brain Injury (NCT05740553) | The University of Texas at Dallas | 2021-11-15 |
| A Trial of CP101 for the Prevention of Recurrent CDI (PRISM4) (NCT05153499) | Finch Research and Development LLC. | 2021-11-15 |
| Pharmacokinetics of Amcenestrant in Female Hepatic Impaired Participants as Compared to Participants With Normal Hepatic Function (NCT05126329) | Sanofi | 2021-11-15 |
| Catheter Ablation of Ventricular Arrhythmia Reduces Skin Sympathetic Activity (NCT04837183) | Mayo Clinic | 2021-11-15 |
| Enabling Family Physicians to Reduce Vaccine Hesitancy and Increase Covid-19 Vaccine Uptake (NCT04963790) | Hopital Montfort | 2021-11-14 |
| Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis (NCT04925557) | State University of New York at Buffalo | 2021-11-13 |
| Point-of-Care Immunoassay for Detection of Bacterial Sinusitis (NCT03584737) | ENTvantage Dx | 2021-11-12 |
| A Study of AC682 for the Treatment of Locally Advanced or Metastatic ER+ Breast Cancer (NCT05080842) | Accutar Biotechnology Inc | 2021-11-12 |
| Safety and Immunogenicity of Adjuvanted SARS-CoV-2 (SCB-2019) Vaccine in Adults With Chronic Immune-Mediated Diseases (NCT05012787) | Clover Biopharmaceuticals AUS Pty | 2021-11-12 |
| Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant (NCT04908735) | Children's Hospital Medical Center, Cincinnati | 2021-11-12 |
| Safety, Tolerability and Efficacy of Uproleselan (GMI-1271) in Patients With COVID-19 Pneumonia (NCT05057221) | Lena Napolitano, MD | 2021-11-12 |
| VAXZEVRIA Japan Post-Marketing Surveillance (PMS) for the Subjects With Underlying Disease at High-risk for Worsening COVID-19 (NCT05084755) | AstraZeneca | 2021-11-11 |
| Particle-based Partial Tumor Irradiation of Unresectable Bulky Tumors (NCT04875871) | EBG MedAustron GmbH | 2021-11-11 |
| Refined Fecal Microbiota Transplantation (FMT) for Ulcerative Colitis (UC) (NCT04968951) | Ari M Grinspan | 2021-11-10 |
| Evaluation of the Effect of Two Online Interventions -Watch Your Weight During the Holidays Program and the Relative 5:2 Fasting- for the Prevention of Body Weight Gain at 8 Weeks in Mexican Adults in the Covid-19 Pandemic (NCT05060978) | Universidad de Sonora | 2021-11-10 |
| Noise-Induced Hearing Loss-Acute Exposure Treatment (UA) (NCT04774250) | Washington University School of Medicine | 2021-11-10 |
| A Study to Test Whether Spesolimab Helps People With Crohn's Disease Who Have Symptoms of Bowel Obstruction (NCT05013385) | Boehringer Ingelheim | 2021-11-09 |
| Proenkephalin A and Kidney Replacement Therapy (NCT04879706) | University of Giessen | 2021-11-09 |
| Study of REGN5093-M114 (METxMET Antibody-Drug Conjugate) in Adult Patients With Mesenchymal Epithelial Transition Factor (MET) Overexpressing Advanced Cancer (NCT04982224) | Regeneron Pharmaceuticals | 2021-11-09 |
| Evaluating the Use of ProKera Plus® in the Management of Bacterial Corneal Ulcers (NCT04850313) | University of Arkansas | 2021-11-09 |
| Effect of GLP-1 Receptor Agonists on Trabecular Bone Score (NCT04964388) | University of Mississippi Medical Center | 2021-11-09 |
| Study of Magrolimab Combinations in Patients With Relapsed/Refractory Multiple Myeloma (NCT04892446) | Gilead Sciences | 2021-11-09 |
| Effect of Ketamine on Neurological Activity as Measured by Electroencephalogram (EEG) (NCT05095792) | Entheon Biomedical Corp. | 2021-11-09 |
| Microvascular Reactivity in Peripheral Artery Disease (NCT05063474) | Columbia University | 2021-11-09 |
| A Research Study Looking Into Levels of the Medicine NNC0385-0434 in the Body and How Well it is Tolerated in Participants With Impaired Kidney Function Compared to Participants With Normal Kidney Function (NCT05094934) | Novo Nordisk A/S | 2021-11-09 |
| Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD (NCT04784143) | Resilient Pharmaceuticals | 2021-11-08 |
| A Study of JNJ-75220795 in Japanese Participants (NCT05039710) | Janssen Pharmaceutical K.K. | 2021-11-08 |
| Circulating Tumour DNA guidEd Therapy for Stage IIB/C mElanoma After surgiCal resecTION (NCT04901988) | The Christie NHS Foundation Trust | 2021-11-08 |
| Impact of Telehealth on Engagement in Psychotherapy and/or Medication Treatment (NCT04931927) | New York State Psychiatric Institute | 2021-11-08 |
| COVID-19 Study to Evaluate Safety, Tolerability, and Efficacy of REGN14256+Imdevimab for the Treatment of COVID-19 Adult and Adolescent Patients Without Risk Factors for Progression to Severe Disease (NCT05081388) | Regeneron Pharmaceuticals | 2021-11-08 |
| Eating Behaviour and Quality of Life of Night Workers in Food and Nutrition Units (NCT05080751) | Pontificia Universidade Católica do Rio Grande do Sul | 2021-11-08 |
| Naxitamab and GM-CSF in Combination With IT in Patients With High-Risk Neuroblastoma (NCT04560166) | Y-mAbs Therapeutics | 2021-11-08 |
| Cervical Interbody Fusion Device Patient Registry (NCT05114356) | Restor3D | 2021-11-08 |
| Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Diabetes (NCT05003908) | The Foundation for Orthopaedics and Regenerative Medicine | 2021-11-06 |
| A Study to Evaluate Safety and Preliminary Anti-tumor Activity of Debio 0123 as Monotherapy in Adult Participants With Advanced Solid Tumors (NCT05109975) | Debiopharm International SA | 2021-11-05 |
| Immunotherapy Combined With Radiation and Influenza Vaccine for Pancreatic Cancer. (NCT05116917) | Herlev Hospital | 2021-11-05 |
| Clofazimine- and Rifapentine-Containing Treatment Shortening Regimens in Drug-Susceptible Tuberculosis: The CLO-FAST Study (NCT04311502) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-11-05 |
| A Phase II Study of Chiauranib in Combine With Capecitabine in TNBC (NCT05336721) | Chipscreen Biosciences, Ltd. | 2021-11-05 |
| COVID-19 Patient Cohort: Retinal Damage in Non-invasive Retinal Imaging (OCTA) (NCT04881253) | Centre Hospitalier Intercommunal Creteil | 2021-11-05 |