| A Study of Nivolumab-relatlimab Fixed-dose Combination Versus Regorafenib or TAS-102 in Participants With Later-lines of Metastatic Colorectal Cancer (NCT05328908) | Bristol-Myers Squibb | 2022-04-28 |
| Long-term Extension Study of Setrusumab in Adults With Type I, III, or IV Osteogenesis Imperfecta (NCT05312697) | Ultragenyx Pharmaceutical Inc | 2022-04-28 |
| Efficacy and Safety of Two Doses of HIL-214 in Children (NCT05281094) | HilleVax | 2022-04-28 |
| A Clinical Study to Evaluate the Safety and Tolerability of JS012 in Advanced or Metastatic Solid Tumors (NCT05388279) | Shanghai Junshi Bioscience Co., Ltd. | 2022-04-28 |
| Multi-Center, Prospective, Randomized Controlled Trial Evaluating SkinTE® in the Treatment of Wagner 2 DFUs (NCT05372809) | PolarityTE | 2022-04-28 |
| A Study to Investigate the Efficacy and Safety of MS-553 in CLL/SLL (NCT05272813) | Shenzhen MingSight Relin Pharmaceuticals Co., Ltd. | 2022-04-28 |
| Informed Choice - Compass (NCT05246839) | Exact Sciences Corporation | 2022-04-28 |
| ST266 Eyedrops for the Treatment of Persistent Corneal Epithelial Defects (NCT05066698) | Noveome Biotherapeutics, formerly Stemnion | 2022-04-27 |
| Study of ALXN2050 in Adult Participants With Generalized Myasthenia Gravis (NCT05218096) | Alexion Pharmaceuticals, Inc. | 2022-04-27 |
| A Randomized Trial of Low-Dose Bevacizumab vs Laser for Type 1 ROP (NCT04634604) | Jaeb Center for Health Research | 2022-04-27 |
| Evaluation of the Efficacy of the Injection of Botulinum Toxin A vs Scopolamine Patches in the Treatment of Drooling in Children With Cerebral Palsy (NCT03616067) | Hospices Civils de Lyon | 2022-04-27 |
| A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) (NCT05161481) | Boehringer Ingelheim | 2022-04-27 |
| Reparixin add-on Therapy to Standard Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia (NCT05254990) | Dompé Farmaceutici S.p.A | 2022-04-27 |
| A Study to Evaluate Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Multiple Doses of Natalizumab (BG00002) Administered Subcutaneously to Japanese Participants With Relapsing-Remitting Multiple Sclerosis (NCT05265728) | Biogen | 2022-04-26 |
| A Phase 2a Study, Effect of Vancomycin With vs Without Delpazolid (LCB01-0371) in Patients With MRSA Bacteremia (NCT05225558) | LigaChem Biosciences, Inc. | 2022-04-26 |
| Intraperitoneal Paclitaxel-loaded TPM for Treatment of Peritoneal Carcinomatosis (NCT05159050) | Carlos Chan | 2022-04-26 |
| Efficacy and Safety of Canakinumab for the Treatment of Anemia in LR-MDS Patients (NCT05237713) | University of Leipzig | 2022-04-26 |
| Implementation of STTR Strategies Among People Who Inject Drugs in Malaysia (NCT03987282) | Yale University | 2022-04-26 |
| Study of Attentional Disorders in Patients Suffering From Idiopathic Generalized Epilepsy. (NCT05530109) | University Hospital, Lille | 2022-04-26 |
| Flecainide Acetate Inhalation Solution for Cardioversion of Recent-Onset, Symptomatic Atrial Fibrillation (NCT05039359) | InCarda Therapeutics, Inc. | 2022-04-26 |
| Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty (NCT05017701) | Masimo Corporation | 2022-04-26 |
| Posoleucel (ALVR105) for the Treatment of Adenovirus Infection in Pediatric and Adult Participants Receiving Standard of Care Following Allogeneic Hematopoietic Cell Transplantation (NCT05179057) | AlloVir | 2022-04-26 |
| A Clinical Study to Evaluate the Efficacy and Safety of LIV-GAMMA SN Inj. in ABO-Incompatible Liver Transplantation (NCT05666453) | SK Plasma Co., Ltd. | 2022-04-25 |
| Senseye's OBCI Diagnostic Tool for PTSD (NCT05372523) | Senseye, Inc. | 2022-04-25 |
| Observation of the Immune Response After COVID-19 Additional Vaccine Doses in Chronic Patients in Hemodialysis Therapy (NCT05142501) | Fresenius Medical Care Deutschland GmbH | 2022-04-25 |
| The Nori Health App (NCT05474742) | UMC Utrecht | 2022-04-25 |
| Safety, Tolerability, and Efficacy of RLS103 in a Clinical Model of Photosensitive Epilepsy (NCT05678881) | Receptor Life Sciences | 2022-04-25 |
| Bioequivalence Study of PMR Compared to Cilostazol IR Tablets in Healthy Volunteers (NCT05191862) | Genovate Biotechnology Co., Ltd., | 2022-04-23 |
| Baloxavir in Combination With Oseltamivir in Allogenic Bone Marrow Transplant Recipients With Influenza (NCT05170009) | Weill Medical College of Cornell University | 2022-04-22 |
| Study of AT-752 in Healthy Subjects in a Dengue Human Challenge Model (NCT05366439) | Atea Pharmaceuticals, Inc. | 2022-04-22 |
| Lefamulin for M. Genitalium Treatment Failures (NCT05111002) | University of Washington | 2022-04-22 |
| Effectiveness of the EmoLED Medical Device in the Healing of Digital Ulcers in Patients With Scleroderma. (NCT05181644) | Emoled | 2022-04-22 |
| A Study of SHR-1802 in Patients With Advanced Solid Tumor (NCT05208177) | Jiangsu HengRui Medicine Co., Ltd. | 2022-04-22 |
| Safety and Efficacy of Enteral Feeding Tube Stoma Site Accessory (NCT05288556) | Eric Yudelevich | 2022-04-22 |
| Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH) (NCT05217667) | Arrowhead Pharmaceuticals | 2022-04-22 |
| Combination of Serabelisib and Insulin Suppressing Diet With or Without Nab-paclitaxel in Subjects With Advanced Solid Tumors With PIK3CA Mutations (NCT05300048) | Faeth Therapeutics | 2022-04-22 |
| Oral Naltrexone In Pediatric Eating Disorders (NCT05073679) | Rosemary Claire Roden | 2022-04-22 |
| SKY Breath Intervention (NCT05388110) | University of California, San Francisco | 2022-04-22 |
| Role of Proton Pump Inhibitors on the Postoperative Course Following Pancreaticoduodenectomy (NCT05251233) | Washington University School of Medicine | 2022-04-21 |
| A Study of SGN-ALPV in Advanced Solid Tumors (NCT05229900) | Seagen Inc. | 2022-04-21 |
| Feasibility of Adherence to Light Therapy (NCT04944758) | University of British Columbia | 2022-04-21 |
| Study to Evaluate the Long-Term Safety and Efficacy of Imsidolimab (ANB019) in the Treatment of Subjects With GPP (NCT05366855) | Vanda Pharmaceuticals | 2022-04-21 |
| Phase 3 Study of Futuximab/Modotuximab in Combination With Trifluridine/Tipiracil Versus Trifluridine/Tipiracil Single Agent in Participants With Previously Treated Metastatic Colorectal Cancer (NCT05223673) | Institut de Recherches Internationales Servier | 2022-04-21 |
| Phase Ib/II Trial of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/Her2- Breast Cancer (NCT04791384) | Criterium, Inc. | 2022-04-21 |
| Open-Label Prospective Study Comparing Long-Term Outcome With or Without HFNC in Patients With Stable Hypercapnic COPD (NCT04840706) | Turku University Hospital | 2022-04-21 |
| First-in-Human Study of TAK-280 in Participants With Solid Tumors (NCT05220098) | Takeda | 2022-04-21 |
| Evaluate the Effects of a Theanine Formulation on Stress, Burnout, Mood, and Sleep in Individuals Who Report Occasional Moderate or High Levels of Stress (NCT05450952) | Supplement Formulators, Inc. | 2022-04-21 |
| Assessment of Heart Failure (HF) At-Home Management Solution ADI Cardio Pulmonary Monitoring System (CPM) (NCT05980585) | Analog Device, Inc. | 2022-04-20 |
| Serial Testing To Assess Cognitive Function In Cancer (NCT06160700) | Indiana University | 2022-04-20 |
| A Study of [225Ac]-FPI-1966 in Participants With Advanced Solid Tumours (NCT05363605) | Fusion Pharmaceuticals Inc. | 2022-04-20 |
| Surgical Outcomes Following Neurectomy Based Upon Response to Local Anesthetic Injection in Chronic Groin Pain (NCT05386693) | The Cleveland Clinic | 2022-04-20 |
| A Study of HFB301001 in Adult Patients With Advanced Solid Tumors (NCT05229601) | HiFiBiO Therapeutics | 2022-04-20 |
| Speed of Processing (SoP) Training Plus α-tACS (NCT05198726) | Portucalense University | 2022-04-19 |
| MVA-BN-RSV Vaccine Trial (NCT05238025) | Bavarian Nordic | 2022-04-19 |
| A Randomized, Double-Blind, Placebo Controlled, Multicenter, Efficacy and Safety Trial of Single Cycle Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain (NCT05359133) | Wex Pharmaceuticals Inc. | 2022-04-19 |
| The Effect of Violet Device Dosed Ultra Violet-C Light (UV-C) Exposure on Healthy Hand Skin (NCT05313555) | University of Michigan | 2022-04-19 |
| Single and Multiple Intravenous Administrations of Estetrol (E4) in Healthy Adult Volunteers (NCT05460065) | NEURALIS s.a. | 2022-04-19 |
| A Study to Evaluate the Efficacy and Safety of Gantenerumab in Participants at Risk for or at the Earliest Stages of Alzheimer's Disease (AD) (NCT05256134) | Hoffmann-La Roche | 2022-04-19 |
| The CONFUCIUS Oral Protein Supplementation Trial (NCT05405764) | ARH van Zanten | 2022-04-19 |
| Clinical Study of BR105 Injection (NCT05351697) | BioRay Pharmaceutical Co., Ltd. | 2022-04-19 |
| Lenvatinib for the Treatment of Recurrent Hepatocellular Carcinoma After Liver Transplant (NCT05103904) | Emory University | 2022-04-19 |
| Dose-ranging Study of Oral PHA-022121 for Prophylaxis Against Angioedema Attacks in Patients With Hereditary Angioedema Type I or Type II (NCT05047185) | Pharvaris Netherlands B.V. | 2022-04-19 |
| A Study to Evaluate the Anti-inflammatory Effects of Letermovir (Prevymis) in Adults With Human Immunodeficiency Virus (HIV)-1 and Asymptomatic Cytomegalovirus (CMV) Who Are on Suppressive Antiretroviral Therapy, Plus Its Effect on Chronic Inflammation, HIV Persistence and Other Clinical Outcomes. (NCT04840199) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-04-19 |
| A Study of WJ05129 in Advanced Malignant Solid Tumors (NCT05326035) | Suzhou Junjing BioSciences Co., Ltd. | 2022-04-19 |
| ASP-1929 Photoimmunotherapy Combined With Pembrolizumab in Patients With Recurrent Head and Neck Cancer, With or Without Metastases (NCT05265013) | Rakuten Medical, Inc. | 2022-04-19 |
| Novel BET Inhibitor PLX51107 for Steroid-Refractory Acute GVHD (NCT04910152) | Hannah Choe, MD | 2022-04-19 |
| Blood Flow Restriction Training in ACL Surgery (NCT05245864) | University of Arkansas | 2022-04-18 |
| Evaluate the Effects of Renal Impairment on the Pharmacokinetics and Pharmacodynamics (NCT05323136) | Shaanxi Micot Pharmaceutical Technology Co., Ltd. | 2022-04-15 |
| International Study of High-Risk Patients for Hepatocellular Carcinoma Using Liquid Biopsy (NCT05342350) | Johns Hopkins University | 2022-04-15 |
| A Long-term Follow-up Study of Patients Who Received VOR33 (NCT05309733) | Vor Biopharma | 2022-04-15 |
| Using Technology to Optimize Collaborative Care Management of Depression in Urban and Rural Cancer Centers, SCOPE (NCT05012124) | University of Washington | 2022-04-15 |
| Development and Validation of a Novel Functional Eye-Tracking Software Application for Neurological Disorders (NCT05212727) | Innodem Neurosciences | 2022-04-15 |
| Hypertension in Young Adults Trial (NCT05370599) | University of California, San Francisco | 2022-04-15 |
| Phase 2 Study of Plamotamab Combined With Tafasitamab Plus Lenalidomide Versus Tafasitamab Plus Lenalidomide in Relapsed or Refractory (R/R) Diffuse Large-cell B-cell Lymphoma (DLBCL) (NCT05328102) | Xencor, Inc. | 2022-04-15 |
| Strategies for Assessment of Fluid Overload in Acute Decompensated Heart Failure (NCT04901039) | Region Skane | 2022-04-14 |
| Study of Intravenously Administered Anti-LIGHT Monoclonal Antibody CBS001 in Healthy Volunteers (NCT05323110) | Capella Bioscience Ltd | 2022-04-14 |
| Study of GSK3965193 in Healthy Participants and Participants Living With Chronic Hepatitis B Infection (NCT05330455) | GlaxoSmithKline | 2022-04-14 |
| CYNK-101 in Combination with Trastuzumab and Pembrolizumab in Patients with Locally Advanced Unresectable or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma (NCT05207722) | Celularity Incorporated | 2022-04-14 |
| A Study Comparing Niraparib Versus Platinum-Taxane Doublet Chemotherapy as Neoadjuvant Treatment in Participants With Homologous Recombination-Deficient Stage III/IV Ovarian Cancer (COHORT-C) (NCT06964165) | Tesaro, Inc. | 2022-04-14 |
| A Sham-Controlled Study to Evaluate the Safety and Efficacy of a Smart, Self-Adjusting, Surgery-Free, Wearable Bladder Neuromodulation System for Overactive Bladder (NCT05381116) | Avation Medical, Inc. | 2022-04-14 |
| A Study of TAK-500 With or Without Pembrolizumab in Adults With Select Locally Advanced or Metastatic Solid Tumors (NCT05070247) | Takeda | 2022-04-14 |
| Prospective Group-Matched Study With Belzupacap Sarotalocan (Bel-sar; AU-011) or Plaque Radiotherapy for Primary Indeterminate Lesions or Choroidal Melanoma (IL/ CM) (NCT05266430) | Aura Biosciences | 2022-04-14 |
| A Study to Assess RAD011 (Cannabidiol Oral Solution) for the Treatment of Participants With Prader-Willi Syndrome (NCT05098509) | Radius Pharmaceuticals, Inc. | 2022-04-13 |
| Phase 2 Study for SAR443820 in Participants With Amyotrophic Lateral Sclerosis (ALS) (NCT05237284) | Sanofi | 2022-04-13 |
| A Study of Various Respiratory Syncytial Virus (RSV) Pre-Fusion (preF)-Based Vaccine Formulations in Adults Aged 60 Years and Older (NCT05327816) | Janssen Vaccines & Prevention B.V. | 2022-04-13 |
| Effectiveness of Brolucizumab in Pre-treated Patients With nAMD in the Real-world Setting (NCT05266495) | Novartis Pharmaceuticals | 2022-04-13 |
| Study to Compare the Pharmacokinetics, Safety and Tolerability of the Pediatric and Adult Branaplam Formulation in Healthy Adults and the Effect of Food on the Latter. (NCT05330286) | Novartis Pharmaceuticals | 2022-04-13 |
| Effects of Riociguat on RIght VEntricular Size and Function in PAH and CTEPH (NCT04954742) | Heidelberg University | 2022-04-13 |
| Does Steroid Plus CO2 Laser Improve Lichen Sclerosus Symptoms Compared to Steroids Alone? (NCT05243563) | University of South Alabama | 2022-04-13 |
| The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study (NCT05229653) | NYU Langone Health | 2022-04-12 |
| Selection of Farnesoid X Receptor (FXR) Ligands on the Reactivation of Latent HIV Proviruses (NCT05219916) | Hospices Civils de Lyon | 2022-04-12 |
| Study of XL114 in Subjects With Non-Hodgkin's Lymphoma (NCT05144347) | Exelixis | 2022-04-12 |
| Quantra® System With the QStat® Cartridge in Trauma (NCT05376462) | HemoSonics LLC | 2022-04-12 |
| Janssen Ad26.CoV2.S Vaccine Booster in Kidney Transplant Recipients (NCT05220397) | Mark Stegall | 2022-04-11 |
| A 3 Arm Randomized Study on Health-related QoL of Elderly Patients With Advanced Soft Tissue Sarcoma (NCT04780464) | European Organisation for Research and Treatment of Cancer - EORTC | 2022-04-11 |
| Efficacy & Safety Evaluation of Enobosarm in Combo With Abemaciclib in Treatment of ER+HER2- Metastatic Breast Cancer (NCT05065411) | Veru Inc. | 2022-04-11 |
| Single Step Lesion Annotation and Localization of Suspicious Breast Lesions (NCT05118295) | M.D. Anderson Cancer Center | 2022-04-11 |
| Natural Progesterone for the Treatment of Recurrent Glioblastoma (NCT05091866) | Emory University | 2022-04-11 |
| Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity (NCT05530434) | University of Mississippi Medical Center | 2022-04-11 |
| A Study of Safety and Efficacy of ATI-2173 and Vebicorvir in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection (NCT05238844) | Antios Therapeutics, Inc | 2022-04-11 |