| A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME) (NCT07425522) | Genentech, Inc. | 2026-04-21 |
| A Trial to Compare the Pharmacokinetics of Two Presentations of Navenibart in Healthy Participants (NCT07635095) | Astria Therapeutics, Inc. | 2026-04-21 |
| Accelerated Temporal Interference Stimulation on Bilateral Subthalamic Nucleus for Parkinson's Disease and Secondary Parkinson's Syndrome (NCT07568067) | Ke Dong, MD | 2026-04-21 |
| A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD) (NCT07227207) | Tessera Therapeutics, Inc. | 2026-04-21 |
| Hertel Exophthalmometry Values in Mexican Adults (NCT07705061) | Instituto de Oftalmología Fundación Conde de Valenciana | 2026-04-21 |
| Ferroptosis Role in the Pathophysiology of Systemic Lupus Erythematosus (NCT07260942) | University Hospital, Bordeaux | 2026-04-21 |
| Study of Tarlatamab + ZL-1310 +/- Anti-programmed Death Ligand 1 (Anti-PD-L1) in Small Cell Lung Cancer (SCLC) (NCT07531095) | Amgen | 2026-04-21 |
| A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation (NCT07458347) | Kestrel Therapeutics, Inc. | 2026-04-21 |
| Continuous Antibiotic Infusion In Children (NCT07575009) | Tampere University Hospital | 2026-04-21 |
| Assessing Ambulatory and Non-ambulatory Community Mobility in People With Lower Limb Amputation (NCT07387744) | Virginia Commonwealth University | 2026-04-21 |
| Efficacy of Early Continuous Infusion of HSS on the Neurological Outcome at 6 Months in TBI Patients. (NCT07319208) | Nantes University Hospital | 2026-04-21 |
| A Study of BL-M07D1 Combined With Pertuzumab Versus Docetaxel Plus Trastuzumab and Pertuzumab in Patients With First-line HER2-positive Recurrent or Metastatic Breast Cancer (NCT07518173) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-04-21 |
| Engagement Study for Participants With Factor V Leiden and Prothrombin G20210A Mutations (NCT07584265) | Richmond Research Institute | 2026-04-21 |
| Contingency Management Plus Deep Transcranial Magnetic Stimulation for the Treatment of Cocaine Use Disorder (NCT07490600) | The University of Texas Health Science Center, Houston | 2026-04-21 |
| GUCY2C Prime-Boost Vaccination for Advanced Colorectal and Small Bowel Adenocarcinomas (NCT07417488) | Thomas Jefferson University | 2026-04-21 |
| A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease (NCT07499232) | Janssen Research & Development, LLC | 2026-04-21 |
| Protein Biomarkers and Host RNA Expression Profiles in Congenital Cytomegalovirus Infection (NCT07635368) | Rigshospitalet, Denmark | 2026-04-21 |
| Changes in Movement, Fitness, and Quality of Life in People With Parkinson's Disease After Different Exercise Programs (NCT07221266) | University of Texas, El Paso | 2026-04-21 |
| Satisfaction of Specific Modes Related to Physical Activity in People Living With Type 1 Diabetes and Using an Hybrid Closed-loop System (NCT07567170) | University Hospital, Grenoble | 2026-04-21 |
| Pediatric Evaluation and Registry for Liver Cholestasis in Canada (NCT07411716) | Children's Hospital of Eastern Ontario | 2026-04-21 |
| Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial (NCT07161726) | University of Alabama at Birmingham | 2026-04-21 |
| A Study of Ozanimod in Pregnant Women With Ulcerative Colitis and Their Offspring (NCT05953402) | Bristol-Myers Squibb | 2026-04-21 |
| Impact of Behavioural Modification Working Toolkit Among Women With Gestational Diabetes Mellitus and Hypertension (NCT07551011) | University of the Punjab | 2026-04-21 |
| The Combined Effect of Mulligan Mobilization, Pain Neuroscience-Based Training, and Core Stabilization Exercises in Frozen Shoulder Patients (NCT07667556) | Yeditepe University | 2026-04-21 |
| AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss (NCT07503210) | Novo Nordisk A/S | 2026-04-21 |
| Ublituximab in Autoantibody Positive Immune Mediated Necrotizing Myopathy (NCT07103746) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-04-21 |
| Neoadjuvant Tislelizumab + LM-302 + S-1 or Tislelizumab + SOX for CLDN18.2-Positive Gastric/GEJ Adenocarcinoma (NCT07569068) | Ruijin Hospital | 2026-04-21 |
| Functional and Aesthetic Outcomes Following Lower Lip Reconstruction (NCT07298070) | Hôpital NOVO | 2026-04-21 |
| Test-Retest Reliability of a Submaximal Exercise Test in Patients With Hip and Knee Osteoarthritis (NCT07383740) | Vastra Gotaland Region | 2026-04-21 |
| Bugitinib Combined With Venetoclax and Cytarabine in Relapsed/Refractory Acute Myeloid Leukemia (NCT07563179) | Shenzhen University General Hospital | 2026-04-21 |
| Characterization of Visual Perception Impairments in Patients With Idiopathic Scoliosis (NCT07356999) | Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française | 2026-04-21 |
| A Phase 1 Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors (NCT07612176) | NEOK Bio, Inc. | 2026-04-21 |
| A Study of the Safety and Efficacy of the Intravenous and Intratumoral Injection of OVV-01 in Patients With Advanced Solid Tumours. (NCT07648472) | Joint Biosciences Ltd. | 2026-04-21 |
| Donidalorsen Treatment in Children With Hereditary Angioedema (NCT07298447) | Ionis Pharmaceuticals, Inc. | 2026-04-21 |
| Physical Profile of Cervicogenic Headache: Comparison With Neck Pain and Healthy Controls (NCT07776275) | Istanbul Medipol University Hospital | 2026-04-21 |
| Study of ZG006 in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors as First-Line Standard Therapy in Participants With Extensive Stage Small-Cell Lung Cancer (NCT07231445) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2026-04-21 |
| JS212 Plus JS111 in EGFR-Mutant Advanced NSCLC: A Phase II Study (NCT07518160) | Shanghai Junshi Bioscience Co., Ltd. | 2026-04-21 |
| Dose Finding Study to Evaluate the Safety of BSB-2002 in Relapsed or Refractory Acute Myeloid Leukemia (AML) Patients With NPM1 Mutation (NCT07566585) | BlueSphere Bio, Inc | 2026-04-21 |
| Clindamycin as an Alternative to Vancomycin in Patients Undergoing Aortic Cardiac Surgery With Extracorporeal Circulation (ECC) (NCT07267013) | Nantes University Hospital | 2026-04-21 |
| Pilot-Testing Strategies to Improve Outcomes for Youth With Type 2 Diabetes by Addressing Health-Related Social Needs (NCT07216118) | University of Pittsburgh | 2026-04-21 |
| Establishing a Reference Framework for Outcomes After Machine-Preserved Liver Transplantation in Europe (NCT07585890) | University Medical Center Groningen | 2026-04-21 |
| VSV-IFNβ-NIS With Ipilimumab and Nivolumab for the Treatment of Advanced or Metastatic Clear Cell Renal Cell Carcinoma (NCT07510334) | Mayo Clinic | 2026-04-21 |
| Study of an AAV Mediated Dual-Payload Gene Therapy in Patients With High Grade Glioma (NCT07346144) | Trogenix ltd | 2026-04-21 |
| Orthorexia Nervosa in Fibromyalgia (NCT06947200) | Beylikduzu State Hospital | 2026-04-20 |
| Sauna for Offline Connections and Interactive, Authentic Living (NCT07223099) | University of California, San Francisco | 2026-04-20 |
| BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia (NCT07360392) | Amasya University | 2026-04-20 |
| Dual Administration Of Intraperitoneal And Intravenous TROP2-Directed CAR-NK With TGF-Beta Receptor 2 (TGFBR2) Knock Out (KO) Therapy For Colorectal Cancer-Related Peritoneal Carcinomatosis: A Phase 1/2 Trial ("Chip-CRC Trial") (NCT07411599) | M.D. Anderson Cancer Center | 2026-04-20 |
| The PreEclampsia Postpartum Prevention Trial (NCT07199283) | Karolinska Institutet | 2026-04-20 |
| Optimizing Parameters of Low-Intensity Focused Ultrasound for Pallidal Modulation in Huntington's Disease (NCT07513844) | First Affiliated Hospital of Fujian Medical University | 2026-04-20 |
| Study of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty. (NCT07582835) | Cardiocentro Ticino | 2026-04-20 |
| RE104 Safety and Efficacy Study in Generalized Anxiety Disorder (NCT07489651) | Reunion Neuroscience Inc | 2026-04-20 |
| Outpatient Midline Catheter in Patients Receiveing Lidocaine Infusion Series. (NCT07555314) | Medical University of Warsaw | 2026-04-20 |
| Plantar Intrinsic Muscles Exercises and Three-dimensional Ankle Foot Exercises Comparative Effect in DPN (NCT07576179) | Riphah International University | 2026-04-20 |
| Screening for Biomarkers of Osteonecrosis of the Femoral Head (NCT07545616) | The First Affiliated Hospital of Xinxiang Medical College | 2026-04-20 |
| CAR-T Combined With ASCT in the Treatment of Relapsed/Refractory Large B-cell Lymphoma With High-risk Factors. (NCT07538635) | Zhejiang Cancer Hospital | 2026-04-20 |
| Acute Power Training Effects in Older Adults (NCT07522398) | Hasselt University | 2026-04-20 |
| Vitamin D Treat-to-Target Strategy for Children With Overactive Bladder-Wet (NCT06201013) | Children's Hospital of Chongqing Medical University | 2026-04-20 |
| Velocity-Based Resistance Training Effects on Inflammation in Older Adults (NCT07566832) | National Taipei University | 2026-04-20 |
| Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015) (NCT07486960) | Merck Sharp & Dohme LLC | 2026-04-20 |
| Targeting Sedentary Behavior Reduction and Physical Fitness Enhancement in Women Before and Beyond Bariatric Surgery- BARIMOV Study Protocol (NCT07663942) | Hospital de Sao Sebastiao | 2026-04-20 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics of GenSci161 in Healthy Adult Participants (NCT07476586) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2026-04-20 |
| Open-label Single-arm Study to Assess the Efficacy of Mirikizumab in Patients With Inflammatory Strictures Due to CD (NCT06997965) | Alimentiv Inc. | 2026-04-20 |
| The HVIP+ Community Model (NCT07539142) | University of Arkansas | 2026-04-20 |
| IBI343 in Combination Therapy for Advanced Malignant Solid Tumors (NCT07483554) | Innovent Biologics (Suzhou) Co. Ltd. | 2026-04-20 |
| The Impact of Surgical Procedures on Postoperative Outcomes in Cataract Phacoemulsification and Analysis of Related Factors (NCT07550907) | Zhongshan Ophthalmic Center, Sun Yat-sen University | 2026-04-20 |
| Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer (NCT07528209) | Sun Yat-sen University | 2026-04-20 |
| An Artificial Intelligence System for Multimodal, Multi-class Diagnosis of Pancreatic Cystic Lesions Based on Endoscopic Ultrasonography (NCT07543263) | Qilu Hospital of Shandong University | 2026-04-20 |
| Caregiver Burden in Caregivers of Patients With Multiple Sclerosis (NCT07549048) | Istanbul Physical Medicine Rehabilitation Training and Research Hospital | 2026-04-20 |
| The Effect of Gentle Human Touch and Stimulus Reduction on Pain and Comfort During Heel Blood Collection in Premature Newborns (NCT07715682) | Kubra Nur Kabakcı Sarıdağ | 2026-04-20 |
| Adaptive Dengue Antiviral Platform Trial (NCT06551844) | Oxford University Clinical Research Unit, Vietnam | 2026-04-20 |
| A Pragmatic Clinical Trial of the WE BEAT Well-Being Education Program in Adolescent Congenital Heart Disease: WE BEAT CHD Study (NCT07525843) | Carelon Research | 2026-04-20 |
| Composite Index for Outcome Burden in Acute Cholangitis (NCT07667166) | Asian Institute of Gastroenterology, India | 2026-04-20 |
| Motivating Core-muscle Exercises With Wearable Sensors, Haptics and Interactive Gaming (NCT07555795) | Imperial College London | 2026-04-20 |
| Access My Breast Cancer Care App (NCT07696637) | University of British Columbia | 2026-04-20 |
| A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE) (NCT07409181) | Boehringer Ingelheim | 2026-04-20 |
| CDK4/6 Inhibitors Combined With Endocrine Therapy for Neoadjuvant Treatment (NCT07366112) | Peking University People's Hospital | 2026-04-20 |
| New York Better Breathing Study (NCT06869447) | Roswell Park Cancer Institute | 2026-04-20 |
| NLRP3 Inflammasome and Physical Therapy in ICU-Acquired Weakness (NCT07017517) | University of Chile | 2026-04-20 |
| Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With High Plaque/Low Gingivitis and High Plaque/High Gingivitis (NCT07614490) | Colgate Palmolive | 2026-04-20 |
| Sacral Erector Spinae Plane Block in Pilonidal Sinus Surgery (NCT07534488) | Medipol University | 2026-04-20 |
| Biofield Therapy for the Support of Immunotherapy-related Symptoms Among Adult Cancer Patients - A Pilot Study (NCT07581080) | University of California, Irvine | 2026-04-20 |
| Clinical Transformation of Bone Reconstruction With Autologous Bone Marrow Mesenchymal Stem Cells in Vitro to Repair Avascular Necrosis of Femur Head (NCT07101562) | The First Affiliated Hospital of Xinxiang Medical College | 2026-04-20 |
| Ivabradine in the Acute Management of Cardiogenic Shock (NCT07714746) | National Institute of Cardiovascular Diseases, Pakistan | 2026-04-20 |
| Swiss ProspectivE Cohort of TRAnsgender and Gender Diverse Individuals - The SPECTRA Study (NCT06774053) | University Hospital, Basel, Switzerland | 2026-04-20 |
| Observational Study to Investigate the Short-term Effects of Transcorneal Electrical Stimulation on Visual Performance (NCT07548944) | Okuvision GmbH | 2026-04-20 |
| Upadacitinib Versus Infliximab as Second-Line Treatment for Acute Severe Ulcerative Colitis(UPRISE) (NCT07550673) | Xijing Hospital of Digestive Diseases | 2026-04-20 |
| Smart Symptom Tracking ALEX Application for Tracking and Monitoring Gastrointestinal Health, Smart Horizons Pilot Trial (NCT07618273) | Mayo Clinic | 2026-04-20 |
| Effect of Montelukast on Inflammatory Markers and Cardiac Injury in Patients With Acute Myocardial Infarction (NCT07537868) | October 6 University | 2026-04-20 |
| Postoperative High-flow Nasal Oxygenation After High-risk Surgery in the Frail Adult (NCT07464730) | Region Stockholm | 2026-04-20 |
| Regenerative Endoscopy in Refractory Perianal Crohn's Disease (NCT07652632) | Asian Institute of Gastroenterology, India | 2026-04-20 |
| Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty (NCT06902714) | University of Alabama at Birmingham | 2026-04-20 |
| Low-Field MRI in Stroke Code Patients (NCT07702968) | Leiden University Medical Center | 2026-04-20 |
| Virtual Reality Mirror Therapy With Focused Object-Directed Attention System (NCT07525713) | National Cheng-Kung University Hospital | 2026-04-20 |
| Screening for Biomarkers of Osteoarthritis (NCT07544823) | The First Affiliated Hospital of Xinxiang Medical College | 2026-04-20 |
| Tissue Engineered Cartilage to Repairing Articular Cartilage Defects (NCT07094100) | The First Affiliated Hospital of Xinxiang Medical College | 2026-04-20 |
| Multicenter Cardiac Decision Impact Study in People With Breast Cancer (NCT07703033) | UMC Utrecht | 2026-04-20 |
| Comparison Between Liquid Fibrin and Soft Laser Effects on Healing and Relapse After Lip Repositioning Surgery (NCT07532161) | Damascus University | 2026-04-20 |
| Comparing the Postoperative Analgesic Efficacy of Anterior Iliac Block and Ilioinguinal-iliohypogastric Block in Inguinal Hernia Surgery (NCT07290881) | Harran University | 2026-04-20 |
| Controlled Cold Exposure Combined With PD-1/PD-L1 Immunotherapy in Solid Tumors (NIVALIS) (NCT07538479) | West China Hospital | 2026-04-20 |
| Prehospital Pulse-dose Glucocorticoid in Patients With ST-segment Elevation Myocardial Infarction 2 - The PULSE-MI 2 Trial (NCT07478003) | Thomas Engstrom | 2026-04-20 |