| Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy (NCT06780670) | Novartis Pharmaceuticals | 2025-02-27 |
| ORIC-114 in Combination With Subcutaneous Amivantamab in Patients With EGFR Exon20 Insertion Mutant NSCLC (NCT06816992) | ORIC Pharmaceuticals | 2025-02-27 |
| The Safety, Tolerability, and Pharmacokinetics of of SYH9017 in Chinese Participants With Overweight and Obesity (NCT06830343) | CSPC Baike (Shandong) Biopharmaceutical Co., Ltd. | 2025-02-27 |
| Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1 (NCT06767514) | Summit Therapeutics | 2025-02-27 |
| Comparison of the Resection Site Order in Simultaneous Approach of Colorectal Liver Metastasis (NCT07272928) | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria | 2025-02-27 |
| Systemic Therapies in the Treatment of Cutaneous T-cell Lymphoma (NCT06588868) | Fondazione Italiana Linfomi - ETS | 2025-02-27 |
| Intervention INC: An Interactive Family-centered mHealth Tool to Reduce Obesity Risk in Urban Minority Preadolescents (NCT05935592) | Tufts University | 2025-02-27 |
| Study to Assess Change in Disease Activity of Risankizumab Treatment in Adult Participants With Moderate to Severe Ulcerative Colitis (NCT06764706) | AbbVie | 2025-02-27 |
| CBIT+TMS R33 Phase (NCT06678737) | University of Minnesota | 2025-02-27 |
| Incorporating Healthy Living Strategies to Aid in Recovery After Acute Pulmonary Embolism (NCT06784492) | University of Rochester | 2025-02-27 |
| Transcutaneous Auricular Vagus Nerve Stimulation as Adjuvant Treatment for Sepsis Patients (NCT07051694) | Third Military Medical University | 2025-02-27 |
| Acceptance and Commitment Therapy Integrated Vestibular Rehabilitation (ACTIVE) RCT (NCT06819904) | University of Pittsburgh | 2025-02-27 |
| Unclassified GENotypes of Autoinflammatory Diseases and AA Amyloidosis (NCT06354322) | Assistance Publique - Hôpitaux de Paris | 2025-02-26 |
| Physical Activity in Bed Rest Hospitalized High-Risk Pregnant Women (NCT06713083) | Montse Palacio | 2025-02-26 |
| Gene Therapy for Alpha 1- Antitrypsin Deficiency (NCT06996756) | Weill Medical College of Cornell University | 2025-02-26 |
| Reducing Breathlessness With Dronabinol in COPD Patients (NCT06473701) | Vejle Hospital | 2025-02-26 |
| Effect of Reduced Vasopressors on Mortality in ECMO-supported Cardiogenic Shock Patients (NCT06862700) | Xiaotong Hou | 2025-02-26 |
| Gut Microbiota-dependent Health Impacts of Haskap Berries (NCT06546020) | Montana State University | 2025-02-26 |
| Evolution of Intracardiac Electrograms Recorded by Left Bundle Branch Pacing Lead in Patients With ICD or CRT-D (NCT06745778) | Medtronic Cardiac Rhythm and Heart Failure | 2025-02-26 |
| Safety and Feasibility of Temporal Interference Brain Stimulation for Treatment in Psychiatric Disorders (NCT07179848) | Taipei Veterans General Hospital, Taiwan | 2025-02-26 |
| A 3-part Study of SYX-5219 in Healthy Volunteers and Participants With Atopic Dermatitis (NCT07558668) | Sitryx Therapeutics Ltd | 2025-02-26 |
| A Phase 1 Study of ARC-001 in Participants Undergoing Third Molar Extraction (NCT06864884) | Arcato Laboratories, Inc. | 2025-02-26 |
| Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine (NCT06464146) | Assistance Publique - Hôpitaux de Paris | 2025-02-26 |
| South Korean Study to Prevent Frailty and Aging-related Diseases Through Lifestyle Intervention (NCT06891573) | Seong Hye Choi, MD | 2025-02-26 |
| Evaluation of the PERC Score and the YEARS Algorithm in the Diagnosis of Pulmonary Embolism in the Emergency Department (NCT07313501) | University Hospital, Strasbourg, France | 2025-02-26 |
| A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee (NCT06884865) | Pacira Pharmaceuticals, Inc | 2025-02-26 |
| Heart Failure in Patients With Diabetes: Cells, Crosstalk and Consequences (NCT06774014) | University of Leeds | 2025-02-26 |
| Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors (NCT02896348) | Spaulding Rehabilitation Hospital | 2025-02-26 |
| Topical Betamethasone Versus Moisturizer in Preventing Radiation Dermatitis in Large-Breasted Patients Treated in the Prone Position (NCT06915857) | Sunnybrook Health Sciences Centre | 2025-02-26 |
| Validation and Scaling of Screening Program for Undiagnosed Myasthenia Gravis-Social Media Campaign Paired With a Self-moderated Assessment (NCT06866483) | ZS Associates | 2025-02-26 |
| Oral Mucosal Graft Versus Labial Graft in Female Urethroplasty (NCT07153861) | Tanta University | 2025-02-26 |
| One Stage Ridge Splitting Using 2 Different Techniques in the Posterior Mandible (NCT06891313) | Cairo University | 2025-02-26 |
| Optimising HFO&VTV in Newborn Infants (NCT06719284) | King's College Hospital NHS Trust | 2025-02-26 |
| Feasibility of a Minimally Invasive Diagnostic Algorithm in Suspected Crohn's Disease (NCT06882993) | Esbjerg Hospital - University Hospital of Southern Denmark | 2025-02-26 |
| Irinotecan Liposomes Combined with Cetuximab + Vermofenib in First-line Failure of Advanced Colorectal Cancer (NCT06763029) | Fudan University | 2025-02-26 |
| A Study of HS-20110 in Participants With Advanced Solid Tumors (NCT06892379) | Hansoh BioMedical R&D Company | 2025-02-26 |
| A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults (NCT06820658) | Mayo Clinic | 2025-02-26 |
| One Stage Ridge Splitting Using 2 Different Techniques in Maxilla (NCT06891261) | Cairo University | 2025-02-26 |
| Comparative Study on the Safety and Efficacy of Using AccuSafe Transseptal Guidewire Versus Traditional Transseptal Needle for Transseptal Puncture in non-or Free- Guidance (NCT07515040) | Second Affiliated Hospital of Nanchang University | 2025-02-26 |
| Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases (NCT06435468) | Hospices Civils de Lyon | 2025-02-26 |
| A Phase 1 Study of IM-1021 in Participants With Advanced Cancer (NCT06823167) | Immunome, Inc. | 2025-02-26 |
| National Multicentre Study on Lipid Profile in Noonan Syndrome and Related Disorders: Trends by Age, Gender and Genotype (NCT07464821) | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 2025-02-26 |
| A Phase 2 Trial of Ivonescimab for Patients With Advanced, Metastatic Salivary Gland Cancers (NCT06805617) | Glenn J. Hanna | 2025-02-26 |
| SON-DP in Participants With Relapsed/Refractory Intolerant to Standard of Care Therapies for Advanced/Metastatic Solid Tumors (NCT06873659) | Qurgen Inc. | 2025-02-26 |
| A Phase I Study of SIM0505 in Participants With Advanced Solid Tumors (NCT06792552) | NextCure, Inc. | 2025-02-26 |
| Pathogen Detection in Infectious Uveitis (NCT04521673) | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 2025-02-26 |
| Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009) (NCT06686394) | Merck Sharp & Dohme LLC | 2025-02-26 |
| UCMSC-Exo for Chemotherapy-induced Myelosuppression in Acute Myeloid Leukemia (NCT06245746) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-02-26 |
| A Clinical Study of SHR-A1811 in the Treatment of HER2-positive Locally Advanced or Metastatic Biliary Tract Cancer (NCT06778031) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-02-26 |
| Phase III Clinical Study of MG-K10 Humanized Mab Injection in Subjects With Prurigo Nodularis (NCT06779136) | Shanghai Mabgeek Biotech.Co.Ltd | 2025-02-26 |
| Feasibility Study of Single-session Solution Focused Consultation to Enhance Treatment Engagement (NCT07116655) | Nanyang Technological University | 2025-02-26 |
| Enhanced Problem-solving Therapy and HIV Engagement Support to Improve Perinatal Mental Health & HIV Outcomes in Malawi (NCT06702722) | University of North Carolina, Chapel Hill | 2025-02-26 |
| I CAN DO Surgical ACP (NCT06090552) | University of California, San Francisco | 2025-02-26 |
| Health Literacy in Geriatric Patients (NCT06971393) | Hamilton Health Sciences Corporation | 2025-02-26 |
| Trastuzumab Emtansine(T-DM1) After Trastuzumab Deruxtecan(T-DXd) in HER2-Positive Breast Cancer in Korea (NCT06928818) | Seoul National University Hospital | 2025-02-26 |
| A Study to Investigate the Safety, Pharmacodynamic and Pharmacokinetic Characteristics of CBP-4888 in Hospitalized Participants With Preterm Preeclampsia and Their Children up to 24 Months (NCT07282171) | Comanche Biopharma | 2025-02-26 |
| Genetic Developmental and Epileptic Encephalopathy Natural History Study for Clinical Trial Readiness (NCT07413211) | Weill Medical College of Cornell University | 2025-02-26 |
| Prokinetics and Body Surface Gastric Mapping in Dyspeptic Patients: Baseline and Treatment Effects (NCT06854120) | University of Auckland, New Zealand | 2025-02-26 |
| Pembrolizumab With Olaparib as Combined Therapy in Metastatic Pancreatic Cancer (NCT05093231) | Cambridge University Hospitals NHS Foundation Trust | 2025-02-26 |
| Effect of Aerobic Exercise With Synchronous Music on Functions Among Medical Students (NCT06788106) | Universiti Sains Malaysia | 2025-02-26 |
| Improved Recovery of Walking in Acquired Muscle Weakness (NCT06786390) | Fondazione Don Carlo Gnocchi ETS | 2025-02-25 |
| US-guided Hydro Dissection vs Fluoroscopy-guided Hydro Dissection for Adhesive Capsulitis (NCT06888791) | Diskapi Teaching and Research Hospital | 2025-02-25 |
| A Phase Ib/II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Patients With Advanced/Metastatic Solid Tumors (NCT06848699) | Shanghai Henlius Biotech | 2025-02-25 |
| Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains (NCT06795451) | University of Cincinnati | 2025-02-25 |
| ABBA CORD: dCBT w/ Abatacept for aGVHD Prophylaxis (NCT06680661) | Leland Metheny | 2025-02-25 |
| Safely Delivered Targeted High-dose Irradiation Followed by Adoptive Immunotherapy with Regulatory and Conventional T Cells to Increase Potency of Hematopoietic Stem Cell Transplantation in High-risk Acute Leukemia (NCT06845592) | University Of Perugia | 2025-02-25 |
| Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma (NCT04199026) | M.D. Anderson Cancer Center | 2025-02-25 |
| The Study of Atezolizumab, Bevacizumab and Memantine in Patients With Hepatocellular Carcinoma (HCC) (NCT06789757) | Inova Health Care Services | 2025-02-25 |
| Predicting Clinical Efficacy of Immunotherapy Using Pre-treatment andContinuousMonitoring of PD-L1 TPS/CPS on CTCs, and Immunity Exhaustion Scores (NCT07396259) | Chang Gung Memorial Hospital | 2025-02-25 |
| Stereotactic Body Proton Therapy for Treatment of Primary Renal Cell Carcinoma (NCT06376669) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2025-02-25 |
| Mobile Cognitive Behavioral Therapy for Stroke (NCT06689878) | Weill Medical College of Cornell University | 2025-02-25 |
| Intracardiac Versus Transesophageal Echocardiographic Guidance for Left Atrial Appendage Occlusion (NCT06348394) | Baylor Research Institute | 2025-02-25 |
| Metabolic Biomarkers Predicting Response to Neoadjuvant Immunotherapy in Non-Small Cell Lung Cancer (NCT07084610) | Hospital das Clínicas de Ribeirão Preto | 2025-02-25 |
| A Study to Compare the Efficacy and Safety of BMS-986489 (BMS-986012+ Nivolumab Fixed Dose Combination) in Combination With Carboplatin Plus Etoposide to That of Atezolizumab With Carboplatin Plus Etoposide as First-Line Therapy in Participants With Extensive-Stage Small Cell Lung Cancer (TIGOS). (NCT06646276) | Bristol-Myers Squibb | 2025-02-25 |
| Gestational Lifestyle & Outcomes Wellness (NCT07263412) | The First Affiliated Hospital with Nanjing Medical University | 2025-02-25 |
| Ambroxol to Slow Progression in Parkinson Disease (NCT05778617) | University College, London | 2025-02-25 |
| Intranasal Insulin for Treatment of Alcohol Use Disorder (NCT05988632) | Brown University | 2025-02-25 |
| Effects of Schroth-Based Exercise on Kyphosis Angle, Muscle Strength, Balance, Pain, and Quality of Life in Hyperkyphosis With Chronic Neck Pain (NCT06835608) | Baskent University | 2025-02-25 |
| Clinical Study of Human Umbilical Cord Mesenchymal Stem Cells Injection in Patients With Decompensated Hepatitis B Cirrhosis (NCT07413549) | Beijing Tuohua Weiye Biotechnology Co., Ltd. | 2025-02-25 |
| Assessing the Immediate Increase in Serum Ferritin After Oral Iron Doses: an Experimental Study in Iron-deficient Women (NCT06851130) | Swiss Federal Institute of Technology | 2025-02-25 |
| Lung Cancer and Aging: Improving Well-being for Older Adults With Lung Cancer (NCT06636721) | Duke University | 2025-02-25 |
| Convergent Mechanisms Underlying Reprometabolic Syndrome in Women (NCT06686537) | University of Colorado, Denver | 2025-02-25 |
| Autologous suraL nervE Grafting to the Substantia nigrA in Patients With Synuclienopathies (NCT06683365) | Craig van Horne, MD, PhD | 2025-02-25 |
| Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits (NCT06387290) | University of Utah | 2025-02-25 |
| Immunonutrition Reduces Acute Esophagitis After Thoracic Radiotherapy in Lung Cancer (NCT06840704) | Hunan Cancer Hospital | 2025-02-25 |
| Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive Disorder (NCT06592833) | Icahn School of Medicine at Mount Sinai | 2025-02-25 |
| Treprostinil in Newborns With Pulmonary Hypertension; a Non-Interventional Study to Collect Data on Drug Utilization, Safety, and Effectiveness (NCT06499363) | Ferrer Internacional S.A. | 2025-02-25 |
| Light Therapy Device for Neonatal Intraventricular Hemorrhage Grade 3 and 4 (NCT06797219) | Rutgers, The State University of New Jersey | 2025-02-25 |
| IO Combined With AI as First-line Treatment for Patients With Soft Tissue Sarcoma(TAIS) (NCT06849986) | Fudan University | 2025-02-25 |
| Εffectiveness of a Digital Social Intervention in Primary Care (NCT06849245) | Queen Mary University of London | 2025-02-25 |
| A Study on Application of Adjustable Headrest in Painless Curettage Surgery for Overweight and Obese Patients (NCT06929000) | Maternal and Child Health Hospital of Hubei Province | 2025-02-25 |
| Effect of a Humanoid Robot With Virtual Reality Games to Train Arm Function in Children With Cerebral Palsy - THRIVE Trial (NCT06881407) | Georgia State University | 2025-02-25 |
| Transdiagnostic Online CBT vs. Care as Usual for Primary Care Patients With Subsyndromal Mental Ill-health ( PRIMARITA-2 ) (NCT06804954) | Karolinska Institutet | 2025-02-25 |
| Papillary Reconstruction Using Three Different Modalities (NCT07159802) | Mansoura University | 2025-02-25 |
| mNEED: a Multicentre, Cluster-randomized, Controlled Trial (NCT06827275) | The First Hospital of Jilin University | 2025-02-25 |
| The Effect of taVNS and Upper GI Motility (NCT07632378) | Daniel Keszthelyi | 2025-02-25 |
| Identifying Patterns in the Breath of Individuals With Breast Cancer (NCT06512350) | Breathe BioMedical Inc | 2025-02-25 |
| Two-cycle and Three-cycle Induction Therapy With Modified TPF Regimen Combined and Camrelizumab for LANPC (NCT06811844) | The First Affiliated Hospital of Xiamen University | 2025-02-25 |
| A Phase II Clinical Study of HRS-1893 in Non-obstructive Hypertrophic Cardiomyopathy (NCT06816251) | Shandong Suncadia Medicine Co., Ltd. | 2025-02-25 |
| University of Central Florida CereBank (NCT06876857) | University of Central Florida | 2025-02-25 |