| Phase III Study to Evaluate the Safety, Efficacy, and Impact on Quality of Life of Capivasertib Alongside Standard-of-care Endocrine Treatment in Patients With HR+/HER2- Advanced Breast Cancer and Progression on Prior Endocrine-based Treatment (NCT07281833) | Women's Cancer Study Group GmbH | 2025-11-27 |
| Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients With Primary IgAN (NCT06994845) | Novartis Pharmaceuticals | 2025-11-27 |
| A Study of Dostarlimab in Combination With Carboplatin-paclitaxel in Chinese Participants With Primary Advanced or Recurrent Endometrial Cancer (EC) (NCT07108270) | GlaxoSmithKline | 2025-11-27 |
| Study of the Efficacy and Safety of ICP-332 in Participants With Prurigo Nodularis (NCT07236099) | Beijing InnoCare Pharma Tech Co., Ltd. | 2025-11-27 |
| A Randomized Controlled Trial of Digital CBT to Treat Addiction: Digital RITch®CBT vs. Standard CBT (NCT05943171) | University of Rochester | 2025-11-27 |
| Evaluation by Confocal Reflectance Microscopy of the Skin Structure of Patients With Atopic Dermatitis Treated With Tralokinumab Biotherapy. (NCT07568665) | Hôpitaux Drôme Nord | 2025-11-27 |
| Safety and Efficacy Evaluation of the iNstroke 4F Thromboaspiration Catheter in Patients With Acute Ischaemic Stroke Due to Primary Distal Medium Vessel Occlusions (DMVO) (NCT07357285) | iVascular S.L.U. | 2025-11-27 |
| Survey of Our Future Healthcare Professionals on Their Training, Knowledge, and Experience Regarding Organ Donation (NCT07351188) | University Hospital, Strasbourg, France | 2025-11-27 |
| A Study of MHB042C in Patients With Advanced Solid Tumors (NCT07192107) | Minghui Pharmaceutical (Hangzhou) Ltd | 2025-11-27 |
| The Peripheral(-Muscle) Oxygenation and Perfusion Score as a New Non-invasive Tool to Predict Elevations in C-reactive Protein Levels in Neonates (NCT07109856) | Medical University of Graz | 2025-11-27 |
| One-Page Truth-Telling Aid for Cancer Disclosure (NCT07730164) | Chang Gung University | 2025-11-27 |
| Study of CM512 Injection in Subjects With Chronic Spontaneous Urticaria(CSU) (NCT07166211) | Keymed Biosciences Co.Ltd | 2025-11-27 |
| Clinical Comparison of Alb-PRF vs PRF on Postoperative Morbidity Following FGG Harvesting (NCT06567548) | Cairo University | 2025-11-27 |
| FL-261 Imaging for Cancer Diagnosis and Staging (NCT07510321) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-11-27 |
| Glucagon-like-peptide-1 Receptor Agonists in Patients Receiving Maintenance Dialysis (NCT07017270) | Unity Health Toronto | 2025-11-27 |
| Is Valacyclovir Non-inferior to Valganciclovir as CMV and EBV Prophylaxis in Kidney Transplant Recipients? A Single-Center Prospective Randomized Pilot Study (NCT07294547) | National Taiwan University Hospital | 2025-11-27 |
| Dupilumab Therapy in Nephrotic Syndrome in Children (NCT07091175) | National University Hospital, Singapore | 2025-11-27 |
| Phase IV Clinical Study of Sequential Vaccination of Sabin Strain and Wild Strain Inactivated Poliovirus Vaccine (NCT07457060) | Sinovac Biotech Co., Ltd | 2025-11-27 |
| Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique) (NCT07098182) | Institut du Cancer de Montpellier - Val d'Aurelle | 2025-11-27 |
| A Prediction Model in Pregnant Women With Aplastic Anemia (NCT07101770) | Peking University People's Hospital | 2025-11-27 |
| A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD (NCT06847542) | Hoffmann-La Roche | 2025-11-27 |
| Regional Versus General Anesthesia for Hip Fracture and Postoperative Oxygenation (NCT07309575) | University of Lisbon | 2025-11-27 |
| A Study of Rocbrutinib in Participants With Relapse or Refractory Non-GCB Diffuse Large B-Cell Lymphoma (NCT07189065) | Guangzhou Lupeng Pharmaceutical Company LTD. | 2025-11-27 |
| Strategic Help With Immunoglobulin to Enhance Protect Against Late Disease (CMV) (NCT06958796) | Camille N. Kotton, MD | 2025-11-27 |
| Towards Restoring Complex Movement After Paralysis: Algorithm Development With Healthy Participants (NCT07236892) | University of California, Los Angeles | 2025-11-26 |
| Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R) (NCT07210086) | City of Hope Medical Center | 2025-11-26 |
| Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma (NCT07048457) | Yale University | 2025-11-26 |
| The Danish Bladder Cancer Group 23 Study - A European Study on Cancer in the Upper Urinary Tract (NCT07077447) | Zealand University Hospital | 2025-11-26 |
| Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With Dyslipidemia (NCT07034690) | Novartis Pharmaceuticals | 2025-11-26 |
| Enhancing Generalization of Virtual Reality Exposure for Public Speaking Anxiety (NCT07323498) | Philipps University Marburg | 2025-11-26 |
| Pre-Op MRI on Margin Status for Transoral Robotic Surgery for HPV+ Tonsillar Squamous Cell Carcinoma (NCT07060261) | Case Comprehensive Cancer Center | 2025-11-26 |
| Single vs Multi-Dose Insulin for Glycemic Control (SUGAR) (NCT07171684) | Rutgers, The State University of New Jersey | 2025-11-26 |
| A Phase II Clinical Trial to Evaluate the Efficacy, Safety, and Pharmacokinetics of SR604 Injection in Patients With Von Willebrand Disease (NCT07640893) | Shanghai RAAS Blood Products Co., Ltd. | 2025-11-26 |
| A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors (NCT07129252) | Crinetics Pharmaceuticals Inc. | 2025-11-26 |
| A Post-Marketing Study to Assess the Efficacy and Safety of Intravenous Polymyxin B and Colistin Methanesulfonate in Patients With Carbapenem-Resistant Gram-Negative Bacterial Infection (NCT06966284) | TTY Biopharm | 2025-11-26 |
| Pharmacokinetic, Safety, Tolerability, and Immunogenicity Comparison of CKD-704 (Risankizumab Biosimilar), With EU-approved Skyrizi®, and US-licensed Skyrizi® in Healthy Adult Participants (NCT07258745) | Chong Kun Dang Pharmaceutical | 2025-11-26 |
| A Study to Describe the Effect of Photobiomodulation (Low Level Laser Therapy) in Reducing the Severity and Incidence of Oral Mucositis (Oral Ulceration) in Oral Cancer Patients Undergoing Radiation Treatment (NCT07387978) | Peter MacCallum Cancer Centre, Australia | 2025-11-26 |
| Robotic Minimally Invasive Inguinal Hernia Repair Post-Market Clinical Study With the DEXTER Robotic System (NCT07181876) | Distalmotion SA | 2025-11-26 |
| The Effect of Oral SPM Supplementation on INflammation-induced Vascular Ageing in Obese Hypertensive Patients (NCT07038252) | Assistance Publique - Hôpitaux de Paris | 2025-11-26 |
| RESOLving INflammation Through Diet for Health (RESOLVIN) (NCT07331103) | Mario Negri Institute for Pharmacological Research | 2025-11-26 |
| Evaluation of the Condition of Patients Receiving EARLY Ravulizumab and Admitted in ICU for gMG Crisis (NCT07411963) | Centre Hospitalier Universitaire de Nice | 2025-11-26 |
| A Study to Evaluate the Efficacy and Safety of Cannabidiol Oral Solution (CBD-OS [GWP42003-P, JZP926]) for the Treatment of Focal-Onset Seizures (NCT07233239) | Jazz Pharmaceuticals | 2025-11-26 |
| A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs (NCT06930625) | Debiopharm International SA | 2025-11-26 |
| A Study to Evaluate the Performance, Usability, and Contrived Result Interpretation of iStatis Gonorrhea Antigen Test (NCT07569900) | bioLytical Laboratories | 2025-11-26 |
| Single-dose,First-in-human of KLA478 (NCT07240675) | Hunan Kelun Pharmaceutical Co., Ltd. | 2025-11-26 |
| Safety and Efficacy of Tarperprumig in Adult Participants With Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (NCT07160608) | Alexion Pharmaceuticals, Inc. | 2025-11-26 |
| Argon Plasma Treatment for Ovarian Endometrioma Compared to Standard Cystectomy (NCT07065214) | Erbe Elektromedizin GmbH | 2025-11-26 |
| A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033) (NCT07227402) | Merck Sharp & Dohme LLC | 2025-11-26 |
| Efficacy of a Topical Palmitated Formulation of Capsaicin (Capsadyn®) In the Treatment of Diabetic Neuropathic Foot Pain (NCT07260656) | Carilion Clinic | 2025-11-26 |
| A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer (NCT07217301) | Takeda | 2025-11-26 |
| Magnesium Sulfate as an Adjuvant to Lidocaine in MPDS Trigger Point Injections Assessed by VAS and sEMG. (NCT07390851) | Cairo University | 2025-11-26 |
| Study of Healthy Aging and Physical Function With Elamipretide (NCT07275424) | David Marcinek | 2025-11-26 |
| Fluid Administration in Ketoacidosis (DRINK) (NCT06541535) | Centre Hospitalier Universitaire de Nice | 2025-11-26 |
| Establishment of a Multimodal Standard Database for Inflammation-related Ophthalmopathy (NCT07628946) | Dan Chen | 2025-11-26 |
| Study of PNPLA3 Genetic Polymorphisms in Patients With Non-Alcoholic Fatty Liver Disease in an Ultramarine Population (AdipoDROMExpo) (NCT07330830) | Centre Hospitalier Universitaire de la Guadeloupe | 2025-11-26 |
| A EUROpean Randomized Study on Blood-thinners and Cholesterol-lowering Treatments to Prevent Future Vascular Events in People With Covert Brain Infarcts (CBI) (NCT07012629) | Aarhus University Hospital | 2025-11-26 |
| First-In-Human Study Evaluating Aneurysm Sac Lining in AAA Patients (NCT07020611) | Life Seal Vascular Inc. | 2025-11-26 |
| Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial (NCT07279077) | Sixth Affiliated Hospital, Sun Yat-sen University | 2025-11-26 |
| Interest of Walking Sticks to Increase Walking Activity of People With Sagittal Imbalance of Spine (NCT07127250) | Assistance Publique - Hôpitaux de Paris | 2025-11-25 |
| ctDNA Testing to Inform Standard-of-Care Treatment Decisions in People With Endometrial Cancer (NCT07270666) | Memorial Sloan Kettering Cancer Center | 2025-11-25 |
| PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS (NCT07142291) | PhenoNet, Inc. | 2025-11-25 |
| A Prospective, Randomized, Single-blind, Controlled, Multi-center Study to Assess the Safety and Performance of MagnetOsTM Compared to Autogenous Bone Graft in Patients Undergoing Hindfoot or Ankle Fusions. (NCT07225751) | Kuros Biosurgery AG | 2025-11-25 |
| BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Urinary Incontinence in Postpartum and Early Post-Childbirth Women (NCT07413692) | BTL Industries Ltd. | 2025-11-25 |
| Medically Tailored Meals for Kids (NCT06814795) | UNC Lineberger Comprehensive Cancer Center | 2025-11-25 |
| A Low-Carb Approach to Treat Type 2 Diabetes in Pediatric Patients (NCT06902077) | University of Alabama at Birmingham | 2025-11-25 |
| DeniLA: Comprehensive Demographics and Clinical Profile of NSCLC Patients: Analyzing Guideline-Concordant Care in First-line Treatment Patterns (NCT07109154) | AstraZeneca | 2025-11-25 |
| Infrared Photobiomodulation in Humans With Epilepsy (NCT07145489) | Beth Israel Deaconess Medical Center | 2025-11-25 |
| Targeted Induction Therapy for Stage III Unresectable EGFR Mutant Positive NSCLC (NCT07742332) | Peng Zhang | 2025-11-25 |
| Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer (NCT07199764) | University of Pennsylvania | 2025-11-25 |
| Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients (NCT07173855) | Scarborough General Hospital | 2025-11-25 |
| Gustabor Phase 1 - AI-based Creation of a Nutritional Plan to Compensate for Chemotherapy-induced Taste Disorders (NCT07040189) | Wuerzburg University Hospital | 2025-11-25 |
| Minto and Eleveld Remifentanil Target Controlled Infusion (TCI) Models: a Clinical Comparison (NCT07259291) | University of Padova | 2025-11-25 |
| Clinical Trial of PCV24 in Infants and Children Aged 2 Months to 5 Years (NCT07300644) | Sinovac Life Sciences Co., Ltd. | 2025-11-25 |
| WAMIF: Prospective Study in Young Women Presenting Acute Myocardial Infarction: Cohort Follow up (NCT07181317) | French Cardiology Society | 2025-11-25 |
| Integration and Interactions Between Visual and Proprioceptive Feedbacks (NCT06931509) | Centre Hospitalier Universitaire de Saint Etienne | 2025-11-25 |
| Comparative Effects of Sensory Augmentation and Neuromodulation on Enhancing Motor Recovery Among Stroke Survivors (NCT07266662) | Lahore University of Biological and Applied Sciences | 2025-11-25 |
| Darbepoetin in Patients Candidates for Liver Transplant. (EPO-LT Trial) (NCT07169643) | Fundacion Clinic per a la Recerca Biomédica | 2025-11-25 |
| SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes (NCT07187531) | SAb Biotherapeutics, Inc. | 2025-11-25 |
| Phase I Clinical Study To Evaluate Pharmacokinetic Profile, Safety, Efficacy and Immunogenicity Of Ipilimumab Biosimilar HLX13 Vs. YERVOY® (US-Sourced YERVOY®) As A First-Line Treatment For Patients With Unresectable Hepatocellular Carcinoma (NCT07176650) | Shanghai Henlius Biotech | 2025-11-25 |
| Evaluation of the Combined Therapy of EH-301 and N-acetylcysteine Together With Riluzole in Amyotrophic Lateral Sclerosis (ALS) (NCT07414212) | Biogipuzkoa Health Research Institute | 2025-11-25 |
| Methylphenidate to Address Attention and Executive Deficits Among Children With Sickle Cell Disease (NCT07226219) | St. Jude Children's Research Hospital | 2025-11-25 |
| Impact of Tildrakizumab on Patient Reported Outcomes in Patients With Moderate-to-severe Psoriasis in Canada (NCT07370766) | Chronicle Academy | 2025-11-25 |
| HALP Score, Blood-Based Inflammatory Indices, and Salivary MMP-8 in Periodontal Disease and Healing After Non-Surgical Therapy (NCT07312045) | Ömer Faruk Okumuş | 2025-11-25 |
| Diabetic Retinopathy Prevalence And Risk Factors (NCT07468058) | Da Nang Family General Hospital | 2025-11-25 |
| A Research Study of a New Medicine, NNC9733-0001, in Healthy Participants and Participants With Type 2 Diabetes (NCT07270731) | Novo Nordisk A/S | 2025-11-25 |
| Momelotinib in VEXAS Syndrome (NCT07098936) | Groupe Francophone des Myelodysplasies | 2025-11-25 |
| A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of TQC3302 Inhalation Spray in Healthy Adult Subjects (NCT07267130) | Chia Tai Tianqing Pharmaceutical (Guangzhou) Co., Ltd. | 2025-11-25 |
| The Effect of a Music Intervention on Postictal Agitation in Electroconvulsive Therapy Patients (NCT06817330) | Erasmus Medical Center | 2025-11-25 |
| A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer (NCT07155174) | AbbVie | 2025-11-25 |
| Nephron-sparing Treatment of Tislelizumab + Nab-Paclitaxel for Renal Pelvic Cancer (NCT07233252) | Tianjin Medical University Second Hospital | 2025-11-25 |
| A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies (NCT07223047) | Bristol-Myers Squibb | 2025-11-25 |
| Towards Digital Management of Paediatric Asthma (NCT06902766) | Assistance Publique - Hôpitaux de Paris | 2025-11-25 |
| Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy (NCT07226765) | Amgen | 2025-11-25 |
| Planning Together: A Couple-based, Multi-level Prenatal Contraceptive Education Program for Economically Marginalized Families (NCT07214012) | University of Tennessee Graduate School of Medicine | 2025-11-25 |
| Effects of tVNS and mCIMT in Chronic Stroke (NCT07272239) | Riphah International University | 2025-11-25 |
| A Phase II Study To Evaluate the Efficacy And Safety Of HRS-1301 In Participants With Dyslipidemia (NCT07229937) | Shandong Suncadia Medicine Co., Ltd. | 2025-11-25 |
| Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Trastuzumab Deruxtecan (NCT07537673) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-11-25 |
| Comparing High and lOw-dose asPirin With Dual anTIplatelet Therapy for Three Months Using prasUgrel and aSpirin Following Coronary Artery Bypass Grafting. (OPTIMUS-CABG Trial) (NCT07195149) | Dolnośląskie Centrum Chorób Serca im.prof. Zbigniewa Religi MEDINET Sp. z o.o. | 2025-11-25 |
| Associations of Cranial Outcomes and Parental Expectations and Satisfaction (NCT07356401) | Gulhane School of Medicine | 2025-11-25 |
| Effects of Mobilization and Caffeine After Cesarean (NCT07369726) | KTO Karatay University | 2025-11-25 |