| Tofersen in Non-SOD1 ALS (NCT07294144) | Washington University School of Medicine | 2025-12-29 |
| Pilot Trial of Colchicine for Graft Failure in CABG (NCT06802926) | Ruijin Hospital | 2025-12-29 |
| Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D (NCT07399678) | Alveus Therapeutics, Inc. | 2025-12-29 |
| A Study of IBI362 in Chinese Adolescents With Obesity or Overweight (NCT07255209) | Innovent Biologics (Suzhou) Co. Ltd. | 2025-12-29 |
| Study to Compare Pharmacokinetics, Efficacy, Safety, and Immunogenicity of MB11 Versus EU-/US-Opdivo® in Subjects With Previously Untreated Advanced [Unresectable or Metastatic] Melanoma (NCT07221734) | mAbxience Research S.L. | 2025-12-29 |
| Effects of Terlipressin and Somatostatin on Portal Pressure in Patients Undergoing Living Donor Liver Transplantation (NCT07304466) | Istanbul Medipol University Hospital | 2025-12-29 |
| Mesenchymal Stem Cell and Exosome Therapy for Diabetic Erectile Dysfunction (NCT07480161) | Ankara City Hospital Bilkent | 2025-12-29 |
| Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors (NCT07288359) | Novartis Pharmaceuticals | 2025-12-29 |
| Platelet Rich Plasma for Musculoskeletal Conditions (NCT07231471) | University of Utah | 2025-12-29 |
| AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer (NCT07218809) | AstraZeneca | 2025-12-29 |
| Saci Nivo Rela for TNBC (NCT06963905) | Yale University | 2025-12-29 |
| Study to Evaluate a New Cartilage Regeneration Platform for Knee Cartilage Repair (NCT07639424) | ROKIT Healthcare | 2025-12-29 |
| A Study to Evaluate the Safety and Efficacy of SCTC21C in Combination With Bortezomib, Lenalidomide and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant (NCT07297329) | Sinocelltech Ltd. | 2025-12-29 |
| A Prospective Cohort Study of Zorifertinib as a First-line Treatment in Patients With Epidermal Growth Factor Receptor-mutant Advanced Non-small Cell Lung Cancer With Central Nervous System (CNS) Metastases (NCT07143045) | Alpha Biopharma (Jiangsu) Co., Ltd. | 2025-12-29 |
| Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature (NCT07386340) | Senseonics, Inc. | 2025-12-29 |
| A Study to Investigate Efficacy and Safety With SAR445399 in Adult Participants With Moderate to Severe Hidradenitis Suppurativa (NCT07225569) | Sanofi | 2025-12-29 |
| Clinical Study to Evaluate the Effects of Oral Delta-9-tetrahydrocannabinol (Δ9-THC) With and Without Alcohol on Perception and Driving Performance in Healthy Adults (NCT07176208) | Food and Drug Administration (FDA) | 2025-12-29 |
| LIFU Mechanisms for PTSD in Healthcare Workers (NCT07164105) | Laureate Institute for Brain Research, Inc. | 2025-12-29 |
| Validation and Precision Treatment of Inflammatory Subphenotypes in Acute Respiratory Distress Syndrome: A Multicenter Cohort Study (NCT07289711) | Southeast University, China | 2025-12-29 |
| A Clinical Trial of Enlicitide and Rosuvastatin in Healthy Adults (MK-0616-039) (NCT07300280) | Merck Sharp & Dohme LLC | 2025-12-29 |
| Study of the Effectiveness of a Systematic Minimal Early Intervention on Care Engagement in Adults With Eating Disorders Requesting Specialized Treatment. (NCT07411807) | Centre Hospitalier St Anne | 2025-12-29 |
| Cognitive and Fusion Prostatic Biopsy (NCT07306741) | Menoufia University | 2025-12-28 |
| External Validation of VVI (NCT07372664) | University of Thessaly | 2025-12-28 |
| Tailoring an Online Platform to Promote Evidence-Based Care for Adults With Neurofibromatosis 1 and Low Health Literacy (NCT07233408) | Massachusetts General Hospital | 2025-12-28 |
| The Efficacy and Safety of the Supraglottic Oxygenation Via Nasotracheal Intubation for Deep Sedation Fiberoptic Bronchoscopy (NCT07389083) | First Affiliated Hospital of Zhejiang University | 2025-12-28 |
| Evaluation of Quality of Life in Patients After Placement of a Modified Double J Ureteral Stent (NCT07275879) | St. Luke's Clinical Hospital, Russia | 2025-12-28 |
| USING A DECISION-MAKING SYSTEM TO SUPPORT THE MANAGEMENT OF FEVER AND ACUTE PAIN IN CHILDREN (NCT07344090) | Qwince Innovation S.r.l. | 2025-12-28 |
| Study on the Mechanism of ADC Drug Evaluation Based on Immune Co-culture of Lung Cancer Organoids (NCT07610616) | Guangzhou Institute of Respiratory Disease | 2025-12-28 |
| Investigating the Feasibility of Combining Virtual Reality and Bilateral Transcranial Direct Stimulation to Improve Upper Limb Recovery in Patients With Stroke (NCT07288385) | King Saud University | 2025-12-28 |
| Retention of Pits and Fissure Sealants on Non Carious vs Initial Carious Enamel Lesions in Posterior Teeth (NCT07330089) | Foundation University Islamabad | 2025-12-27 |
| ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma (NCT07098364) | Fred Hutchinson Cancer Center | 2025-12-27 |
| An Early Clinical Study to Evaluate the Safety and Efficacy of CLDN18.2 CAR T Cell Injection in Subjects With CLDN18.2-Positive Advanced Malignant Solid Tumors (NCT07680257) | Celest Therapeutics (Shanghai) Co., Ltd. | 2025-12-27 |
| A Clinical Study to Evaluate the Safety, and Tolerability of BBM-P002 in the Treatment of Parkinson's Disease (NCT07195825) | Shanghai Xinzhi BioMed Co., Ltd. | 2025-12-27 |
| Effect of Single Dose Intravenous Magnesium Sulfate on Postoperative Analgesic Consumption in Patients Undergoing Laparoscopic Cholecystectomy (NCT07328893) | Tata Main Hospital | 2025-12-27 |
| Neuromuscular Variables and Performance in Mexican Weightlifters (NCT07277335) | Ángel Rodríguez | 2025-12-27 |
| Evaluate the Feasibility and Effectiveness of a Community-based Care Bundle in Managing and Preventing Pressure Injuries (NCT07074743) | Singapore General Hospital | 2025-12-26 |
| Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy (NCT07327905) | Alexandria University | 2025-12-26 |
| Efficacy and Safety Phase III Clinical Study of VC005 Tablets in Subjects With Active Ankylosing Spondylitis. (NCT07172360) | Jiangsu vcare pharmaceutical technology co., LTD | 2025-12-26 |
| An AI-Generated, Personalized Question Prompt List Intervention for Patients With Hematologic Cancers (NCT07226934) | Washington University School of Medicine | 2025-12-26 |
| A Prospective Observational Study of First-Line Systemic Therapy Combined With Celiac Plexus Blockade for Advanced Biliopancreatic Cancer With Pain (NCT07326137) | Tongji Hospital | 2025-12-26 |
| Assessment of the Efficacy and Safety of Injectable TQB2934 (Subcutaneous Injection) in Systemic Light Chain Amyloidosis Patients (NCT07266116) | Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. | 2025-12-26 |
| Clinical Trial on the Safety, Tolerance and Preliminary Efficacy of XH001 Injection Combined With Neoantigen Vaccine-induced Tumor-specific T-cell Injection in Advanced Gastric Cancer (NCT07298200) | Jia Wei | 2025-12-26 |
| Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of ZX-8177 in Patients With Advanced Solid Tumors (NCT07310134) | Nanjing Zenshine Pharmaceuticals | 2025-12-26 |
| Single-cell and Spatial Transcriptomic Profiling of Gingival Tissues in Aggressive and Chronic Periodontitis: Deciphering Cellular Heterogeneity and Inflammatory Microenvironment Features (NCT07487272) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-12-26 |
| Noninvasive Real-Time Arterial Waveform Monitoring for Cardiovascular Disease Assessment (NCT07350629) | Anhui Provincial Cancer Hospital | 2025-12-26 |
| A Phase I/II Clinical Trial of Intramyocardial Injection of HucMSCs for the Treatment of Chronic Heart Failure (NCT07265349) | Tasly Pharmaceutical Group Co., Ltd | 2025-12-26 |
| Fibromyalgia Disease Burden in Mothers of Children With Attention-Deficit/Hyperactivity Disorder (NCT07327775) | Sultan 1. Murat State Hospital | 2025-12-26 |
| Peg IFNα-2b Therapy for Unresectable Mid to Late Stage HBV-HCC (NCT07769827) | Jinling Hospital, China | 2025-12-26 |
| Mindfulness-Based Emotion Regulation Training for Hospitalized Children (NCT07379021) | Ataturk University | 2025-12-26 |
| Implementation of a Caregiver-Report Suicide-Risk Screener in Children Under Age 8 in a Behavioral Health Center (NCT07350161) | Washington University School of Medicine | 2025-12-26 |
| Mind-body Skills Groups for War-Related Trauma in Adolescents in Gaza (NCT07302984) | The Center for Mind-Body Medicine | 2025-12-26 |
| A Prospective Observational Study Evaluating the Incidence of Silent Cerebral Lesions and Procedural Safety Following Atrial Fibrillation Ablation Using the VARIPULSE™ Pulsed Field Ablation System (NCT07363278) | Seoul National University Hospital | 2025-12-26 |
| ERAS-Based Preoperative Nutrition and Fasting in Total Knee Arthroplasty (NCT07336160) | Nermin Ocaktan | 2025-12-26 |
| GSL Synthetase Inhibitor Eliglustat Combined With CD30 Target Immunotherapy for the Treatment of of CD30+ Lymphoma (NCT07138547) | Chinese PLA General Hospital | 2025-12-26 |
| Assess Accuracy of Primary Care Asthma and COPD Diagnosis Using Oscillometry and FeNO vs Specialist Diagnosis (NCT07245576) | AstraZeneca | 2025-12-26 |
| Improving Diabetes Care With Strategies For Addressing Health-Related Social Needs and Community Partnerships (NCT07043426) | Boston Medical Center | 2025-12-26 |
| ReAl-woRld Evaluation of tEzepelumab for Chronic rhinoSinusitis With Nasal Polyps in Russia (NCT07399665) | AstraZeneca | 2025-12-25 |
| A Phase Ib Study of HW211026 Ointment in Patients With Actinic Keratosis. (NCT07318675) | Hubei Bio-Pharmaceutical Industrial Technological Institute Inc. | 2025-12-25 |
| Romiplostim N01 for Chemotherapy-Induced Thrombocytopenia in Pediatric Cancer Patients (NCT07043894) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-12-25 |
| A Trial of Hydroxynidone Capsules in Single-dose Administration for Patients With Renal Insufficiency (NCT07262333) | Beijing Continent Pharmaceutical Co, Ltd. | 2025-12-25 |
| The Effect of Using Weighted Blanket on Anxiety, Stress, Depression and Comfort Level Among Patients With Cancer Undergoing Intravenous Anticancer Therapy and Its Feasibility of Use by Nurses Compared to Routine Care (NCT07653035) | Sultan Qaboos Comprehensive Cancer Center | 2025-12-25 |
| 68Ga-BCMA PET/CT in Multiple Myeloma (NCT07319897) | Peking University First Hospital | 2025-12-25 |
| Gut Microbiota and Diarrhea in Breast Cancer Patients Receiving Pyrotinib (NCT07264985) | Hubei Cancer Hospital | 2025-12-25 |
| Efficacy and Safety of Tenecteplase Bridging Mechanical Thrombectomy for Acute Large Vessel Occlusion Stroke (NCT06658197) | Xuanwu Hospital, Beijing | 2025-12-25 |
| Neoadjuvant Trastuzumab-rezetecan Plus Pertuzumab or Nab-Paclitaxel, Carboplatin, Trastuzumab, and Pyrotinib After Suboptimal Response to Neoadjuvant Dual HER2-Targeted Therapy Combined With Chemotherapy in HER2-Positive Early Breast Cancer (NCT07340398) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-12-25 |
| Evaluation of AmblyoFix for the Treatment of Unilateral Amblyopia in Children (NCT07323953) | Eyesight Electronics | 2025-12-25 |
| MAGNATE-S: Paclitaxel Polymer Micelles Combo in Advanced Sarcoma (NCT07359053) | Shanghai 6th People's Hospital | 2025-12-25 |
| To Check Comparison of Apremilast and Methotrexate Efficacy in Patients With Moderate to Severe Plaque Psoriasis Presented to Tertiary Care Hospital (NCT07337434) | Syeda Sana Zaman | 2025-12-25 |
| QL1706 in Combination With Bevacizumab and RALOX HAIC for Hepatocellular Carcinoma With Vp3/4 PVTT (NCT07327788) | Nanfang Hospital, Southern Medical University | 2025-12-25 |
| Real-World Effectiveness of Aztreonam-Avibactam Against MBL-Producing CRE (NCT07268560) | Sir Run Run Shaw Hospital | 2025-12-25 |
| Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study (NCT07224607) | Cedars-Sinai Medical Center | 2025-12-25 |
| Sequential Combined Versus Single-Strategy Adrenal Venous Sampling for Primary Aldosteronism(SCOPE) (NCT07298954) | Shumin Yang | 2025-12-25 |
| Assessment Of Difficult Airway Predictors: A Prospective Comparison Of Upper Airway Ultrasound And Conventional Anthropometric Measures (NCT07309978) | Saglik Bilimleri Universitesi Gulhane Tip Fakultesi | 2025-12-25 |
| Jaw Tracking Impact on Occlusion and Patient Outcomes in Maxillary Implant Restorations (NCT07693946) | Mansoura University | 2025-12-25 |
| ACB With S-ESPB Versus ACB With iPACK for Knee Arthroplasty (NCT07288970) | Poznan University of Medical Sciences | 2025-12-25 |
| Zanubrutinib, Obinutuzumab Combined With Lenalidomide (ZGR) for the Treatment of Untreated Follicular Lymphoma (NCT07299149) | Institute of Hematology & Blood Diseases Hospital, China | 2025-12-25 |
| The Effect of Collagen Scaffold Augmentation in Achilles Tendon Rupture Repair (NCT07130357) | Chinese University of Hong Kong | 2025-12-25 |
| To Evaluate Early (2-Week) vs. Standard (4-Week) Metal Stent Removal Following Endoscopic Ultrasound Guided WON Drainage (NCT07307248) | Asian Institute of Gastroenterology, India | 2025-12-25 |
| Predicting Difficult Intubation in Bariatric Surgery: Comparison of El Ganzouri Risk Index and Airway Ultrasound (NCT07316179) | Antalya Training and Research Hospital | 2025-12-25 |
| Prospective Randomized Controlled Clinical Study of Acupoint Application With Gutong Plaster in the Treatment of Moderate to Severe Cancer Pain (NCT07657390) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-12-25 |
| A Multicenter, Prospective Clinical Trial With a Concurrent Control Evaluating Methotrexate Combined With Rituximab,Sintilimab and Pirtobrutinib vs. Investigator-Selected Standard of Care in Treatment-Naive PCNSL (NCT07350850) | Tongji Hospital | 2025-12-25 |
| Effect of Exergaming Program Versus Neuromuscular Exercise in Elderly People With Motor Cognitive Risk Syndrome (NCT07045259) | Istanbul University - Cerrahpasa | 2025-12-25 |
| Single and Multiple Dose Pharmacokinetics (PK) of Aramchol From an Aramchol Meglumine Tablet (NCT07251712) | Galmed Pharmaceuticals Ltd | 2025-12-25 |
| EMMVIES : Walking Training at Home in VIrtual Reality for Children With Chronic Illnesses Impacting Physical Health (NCT07021638) | University Hospital, Angers | 2025-12-24 |
| Comparing Articular Noise and Its Perception Between Two Different Types of Total Knee Arthroplasty (NCT06880497) | Elsan | 2025-12-24 |
| JS107 vs Investigator's Choice as Second-line or Later Therapy for Advanced CLDN18.2-Positive Gastricor GEJ Adenocarcinoma. (NCT07284134) | Shanghai Junshi Bioscience Co., Ltd. | 2025-12-24 |
| Olanzapine for Managing Anorexia in Head and Neck Cancer Patients Undergoing Chemoradiation, MACRO Trial (NCT06995508) | Roswell Park Cancer Institute | 2025-12-24 |
| β-alanine in the Treatment of Advanced Hepatocellular Carcinoma (NCT07317414) | Peking Union Medical College Hospital | 2025-12-24 |
| Safety and Efficacy Study of RXIM002 in Severe, Relapsed or Refractory Autoimmune Diseases (NCT07322718) | Ruijin Hospital | 2025-12-24 |
| Group vs Individual MDMA-Assisted Therapy for PTSD After the October 7, 2023 Events (NCT07469098) | Sheba Medical Center | 2025-12-24 |
| Prescription Support System for Antimicrobial Use in Belgian Primary Care (NCT07347015) | KU Leuven | 2025-12-24 |
| Exercise Prescription in Children With Hypertrophic Cardiomyopathy (NCT07595354) | Alder Hey Children's NHS Foundation Trust | 2025-12-24 |
| A Phase II Clinical Study Evaluating the Effectiveness of Injectable NC527-X in Intraoperative Imaging for Patients With Solid Tumors (NCT07538648) | Zhejiang Cancer Hospital | 2025-12-24 |
| Combination Letermovir and Standard of Care Antiviral for Enhanced Antiviral Response in Cytomegalovirus Infection in Lung Transplant Recipients (NCT07235683) | University Health Network, Toronto | 2025-12-24 |
| Acupuncture for Refractory Rosacea: A Study on Its Effectiveness and Safety (NCT07296497) | Xiangya Hospital of Central South University | 2025-12-24 |
| ctDNA-guided Treatment Decision-making (NCT07394218) | Fudan University | 2025-12-24 |
| An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania (NCT07288320) | Neurocrine Biosciences | 2025-12-24 |
| Compilation and Preliminary Application of the Active Health Behavior Scale in Patients With Type 2 Diabetes (NCT07531459) | Yun Ye | 2025-12-24 |
| Assessment of the Efficacy and Safety of a DYnaMic Peripheral DegradatiON Myopia Disorder Control in Myopic Children ״DYMOND Study״ (NCT07390500) | NovaSight | 2025-12-24 |
| The CONQUER Trial - Cessation Of Nicotine, QUitting With E-cigarette Reduction (NCT07322432) | VapeAway | 2025-12-24 |