| A Single-arm Phase II Trial of SAcituzumab Govitecan and Trastuzumab for HER2+ Metastatic Breast Cancer After Trastuzumab dEruxtEcaN (SATEEN) (NCT06100874) | Adrienne G. Waks | 2023-11-20 |
| A Phase III, Active-Controlled Study of SHR-A1811 Versus Trastuzumab Emtansine (T-DM1) in HER2-Positive Primary Breast Cancer Participants With Residual Invasive Disease Following Neoadjuvant Therapy (NCT06126640) | Jiangsu HengRui Medicine Co., Ltd. | 2023-11-20 |
| Hepatoprotective Measures for Children at High Risk of NAFLD (NCT06918080) | Ain Shams University | 2023-11-19 |
| Project Looking-Glass Evaluation (NCT06056063) | Abramson Cancer Center at Penn Medicine | 2023-11-19 |
| The Present Study Was Performed to Evaluate the Efficacy of Lyophilized-PRF in Treatment of Periodontal Intra-bony Defects (NCT06625528) | Al-Azhar University | 2023-11-19 |
| Retrospective Observational Study of Patients Who Have Undergone Coronary Artery Bypass Graft (CABG) and/or Cardiac Valve Surgery (NCT07009340) | Renibus Therapeutics, Inc. | 2023-11-18 |
| CHemical OptImization of Cerebral Embolectomy 2 (CHOICE 2). (NCT05797792) | Hospital Clinic of Barcelona | 2023-11-18 |
| A Study to Learn About the Study Medicine Called PF-07868489 in Healthy Adult People and in People With Pulmonary Arterial Hypertension (NCT06137742) | Pfizer | 2023-11-17 |
| An Evaluation of the Effectiveness of a Maternal, Neonatal and Child Health Component for Matasa Matan Arewa and Smart Start Targeting Married Adolescent Girls in Nigeria and Ethiopia (NCT06680765) | Population Services International | 2023-11-17 |
| The PEERLESS II Study (NCT06055920) | Inari Medical | 2023-11-17 |
| Natural History Study in Patients With PDE6A-, PDE6B- and RHO-linked Retinitis Pigmentosa (NCT06323772) | University Hospital Tuebingen | 2023-11-17 |
| A Study of AK104 Plus Axitinib in Advanced/Metastatic Special Pathological Subtypes of Renal Cell Carcinoma (NCT05808608) | Hao Zeng | 2023-11-17 |
| Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102) (NCT06101329) | Gilead Sciences | 2023-11-17 |
| Study of TT-00420 (Tinengotinib) in Subjects With Cholangiocarcinoma Who Failed or Relapsed to Chemotherapy and FGFR Inhibitor (NCT06057571) | TransThera Sciences (Nanjing), Inc. | 2023-11-17 |
| Durvalumab Plus Etoposide-free Chemotherapy in First-line Treatment of Extensive-disease Small-sell Lung Cancer (SCLC) (NCT05856695) | Intergroupe Francophone de Cancerologie Thoracique | 2023-11-17 |
| Monitoring Biomarker for Detecting Change in Physical Activity and Limb Function in Inclusion Body Myositis Over Time (NCT06153108) | University of Kansas Medical Center | 2023-11-16 |
| OP-1250 (Palazestrant) vs. Standard of Care for the Treatment of ER+/HER2- Advanced Breast Cancer (NCT06016738) | Olema Pharmaceuticals, Inc. | 2023-11-16 |
| Initial Staging of Lobular Breast Carcinoma: Head to Head Comparison of 68Ga-FAPI-46 and 18F-FDG PET/CT (NCT05931302) | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | 2023-11-16 |
| A Digital Therapeutic to Improve Insomnia in Multiple Sclerosis: A Randomized Controlled Trial. (NCT06113666) | St. Olavs Hospital | 2023-11-16 |
| ZN-c3 + Gemcitabine in Pancreatic Cancer (NCT06015659) | Brandon Huffman, MD | 2023-11-16 |
| CARegiver BURden, Effectiveness and Other Health Care Measures on Functional Disability, in Patients Treated With Abobotulinumtoxin A for Upper Limb Spasticity (NCT06245772) | Ipsen | 2023-11-16 |
| Effects of Topical Fluoride in Orthodontic Patients (NCT07091890) | Universita di Verona | 2023-11-16 |
| Optimal Timing of Computerized Cognitive Training for Older Intensive Care Unit Survivors (NCT05467410) | University of Washington | 2023-11-15 |
| Macronutrients in Lactating NICU Parents - Impact of Kangaroo Care (NCT06047470) | University of California, Davis | 2023-11-15 |
| Disparities Among Liver Transplant Patients (NCT05981196) | Mayo Clinic | 2023-11-15 |
| Phase 3b Study to Assess the Efficacy, Safety, and Tolerability of Remibrutinib in Comparison to Placebo, With Omalizumab as Active Control, in Adult CSU Patients, Followed by an Open-label 52-week Optional Extension. (NCT06042478) | Novartis Pharmaceuticals | 2023-11-15 |
| Transcutaneous Spinal Cord Stimulation to Promote Walking Recovery After Spinal Cord Injury (NCT05982171) | Craig Hospital | 2023-11-15 |
| Three-Axis Wearable Adaptive Vestibular Stimulator (NCT06106256) | Mayo Clinic | 2023-11-15 |
| Effect of a Health Pathway for People With Persistent Symptoms Covid-19 (NCT05787366) | Centre Hospitalier Universitaire de Saint Etienne | 2023-11-15 |
| Effects of Dapagliflozin on Progression of Alport Syndrome (NCT06226896) | Nanjing University School of Medicine | 2023-11-15 |
| A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis (NCT06136741) | Nektar Therapeutics | 2023-11-15 |
| Non-interventional Study (NIS) on Sodium-glucose Co-transporter-2 Inhibitors (SGLT2i) Use in France (NCT05882071) | Boehringer Ingelheim | 2023-11-15 |
| The Use of MicroRNAs Dysregulation as Potential Biomarkers for Effective Diagnosis of Endometriosis (NCT06168097) | Asian Institute of Gastroenterology, India | 2023-11-15 |
| Artificial Intelligence and Dysplasia Detection in Inflammatory Bowel Disease (EIIDISIA Study) (NCT06281392) | Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana | 2023-11-15 |
| Moderators and Mediators (M & M Trial) of Psychosocial Treatments of Chronic Pain (NCT06044649) | Rush University Medical Center | 2023-11-15 |
| A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients (NCT06292923) | Tiziana Life Sciences LTD | 2023-11-15 |
| A Phase 3 Study Comparing TLL-018 to Tofacitinib in RA Subjects With Inadequate Response or Intolerance to bDMARDs (NCT06020144) | Hangzhou Highlightll Pharmaceutical Co., Ltd | 2023-11-15 |
| A Post-Market Study for Long-Term Effectiveness and Safety of the TOMAC System for RLS (NCT06076499) | Noctrix Health, Inc. | 2023-11-15 |
| A Study to Assess Adverse Events and Change in Disease Activity of Risankizumab Subcutaneous Induction Treatment for Moderately to Severely Active Crohn's Disease. (NCT06063967) | AbbVie | 2023-11-15 |
| A Platform Study of Novel Immunotherapy Combinations as First-Line Treatment in Participants With PD-L1 Positive Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck- GALAXIES H&N-202 (NCT06062420) | GlaxoSmithKline | 2023-11-14 |
| Evolution of CMV Antiviral T-cell Immunity Over the Next Six Months Initiation of Treatment With Belatacept. (NCT05708534) | University Hospital, Rouen | 2023-11-14 |
| A Trial to Learn if Odronextamab Combined With Chemotherapy is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Chemotherapy for Adult Participants With Follicular Lymphoma (NCT06097364) | Regeneron Pharmaceuticals | 2023-11-14 |
| A Study of Disitamab Vedotin in Previously Treated Solid Tumors That Express HER2 (NCT06003231) | Seagen, a wholly owned subsidiary of Pfizer | 2023-11-14 |
| Feasibility of Physical Activity in Older Adults With Haematological Malignancies: ACCES Study (NCT06102876) | University Hospital, Toulouse | 2023-11-14 |
| A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer (NCT06112379) | AstraZeneca | 2023-11-14 |
| [177Lu]Lu-NeoB in Combination With Ribociclib and Fulvestrant in Participants With ER+, HER2- and GRPR+ Advanced Breast Cancer (NCT05870579) | Novartis Pharmaceuticals | 2023-11-13 |
| Screening Using Portable Electronic Recorders for Sleep Apnea in Hypertensive At-Risk Populations (SUPER-SHARP Trial) (NCT05918120) | Sunnybrook Health Sciences Centre | 2023-11-13 |
| Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma (NCT05784012) | Grupo Español de Tratamiento de Tumores de Cabeza y Cuello | 2023-11-13 |
| The PIFPAF-PFA Study (NCT05986526) | Insel Gruppe AG, University Hospital Bern | 2023-11-13 |
| Neoadjuvant Tislelizumab With Chemotherapy for the Treatment of MSS Colon Cancer (NCT06124378) | First Affiliated Hospital of Guangxi Medical University | 2023-11-13 |
| Assessing the Time Demands of Cancer (NCT05708703) | Masonic Cancer Center, University of Minnesota | 2023-11-13 |
| Peer Engagement in Methamphetamine Harm-Reduction With Contingency Management (PEER-CM) (NCT05700994) | Oregon Health and Science University | 2023-11-13 |
| Trial of Efficacy and Safety of MC0518 Versus Best Available Therapy in Participants With Steroid-Refractory Acute Graft Versus Host Disease (NCT06075706) | medac GmbH | 2023-11-13 |
| TmCD19-IL18 in CD19+ Cancers (NCT05989204) | University of Pennsylvania | 2023-11-13 |
| Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004) (NCT06074588) | Merck Sharp & Dohme LLC | 2023-11-12 |
| Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab (NCT06107413) | AbbVie | 2023-11-12 |
| Sipuleucel-T Based Autologous Cellular Immunotherapy for Advanced Prostate Cancer (NCT05806814) | University of Oklahoma | 2023-11-12 |
| The Trial of a New Infant Formula in Healthy Term Chinese Infants (NCT06053112) | Junlebao Dairy Group Co., Ltd. | 2023-11-12 |
| Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL) (NCT06073821) | BeOne Medicines | 2023-11-11 |
| Immunogenicity, Safety, and Antibody Persistence of Different Immunization Strategies Against Japanese Encephalitis (NCT06825312) | Liaoning Chengda Biotechnology CO., LTD | 2023-11-11 |
| Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection (NCT06189183) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2023-11-11 |
| Improving Pulmonary Hypertension Screening by Echocardiography (NCT06038149) | Royal United Hospitals Bath NHS Foundation Trust | 2023-11-11 |
| Effect of Eurycoma Longifolia (DLBS5055) and Multivitamins (Vitamin C+Vitamin E+ β-carotene) for Infertile Males (NCT06100432) | Duta Wacana Christian University | 2023-11-11 |
| Comparative Study on AQP4 Antibody Detection Methods (NCT06767020) | First Affiliated Hospital of Chongqing Medical University | 2023-11-11 |
| A Study on the Immune Response and Safety of a Vaccine Against N. Meningitidis Serogroup B Infection in Healthy Infants From 2 Months of Age (NCT06113198) | GlaxoSmithKline | 2023-11-10 |
| A Study of Cabozantinib and Nivolumab With Radiation Therapy for People With Renal Cell Carcinoma That Has Spread to the Brain (NCT06132945) | Memorial Sloan Kettering Cancer Center | 2023-11-10 |
| A Safety Study of 212Pb-VMT-alpha-NET in Patients With Neuroendocrine Tumors (NCT06148636) | David Bushnell | 2023-11-10 |
| A Study Evaluating Efruxifermin in Subjects With Non-invasively Diagnosed Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Nonalcoholic Fatty Liver Disease (NAFLD)/Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (NCT06161571) | Akero Therapeutics, Inc | 2023-11-10 |
| Clinical Evaluation of Composite Restorations Using Two-steps Universal Adhesive in Non-carious Cervical Lesion (NCCL) (NCT05573243) | Mahidol University | 2023-11-10 |
| Single-Cell Sequence Technology Used to Reveal Heterogeneity of Secondary Hyperparathyroidism (NCT06130683) | China-Japan Friendship Hospital | 2023-11-10 |
| The Expression of CD24 "do-not-eat-me" Signal in Cholangiocarcinoma (NCT06707025) | Hadassah Medical Organization | 2023-11-10 |
| CRISOL Mente: A Multilevel Community Intervention to Reduce Mental Health Disparities Among Latinos (NCT06139159) | Drexel University | 2023-11-10 |
| Study to Assess the Safety and Effectiveness of NMRA-335140-501 (NCT06029439) | Neumora Therapeutics, Inc. | 2023-11-10 |
| Evaluate the Safety, Tolerability of BAT6026 (NCT06094179) | Bio-Thera Solutions | 2023-11-09 |
| Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400 (NCT06084481) | AbbVie | 2023-11-09 |
| To Compare the Effect of Closed Kinetic Chain and Isometric Exercises in Reducing Pain and Improving Functional Disability in Patients With Patellofemoral Pain Syndrome Associated With Knee Osteoarthritis (NCT07298798) | Dow University of Health Sciences | 2023-11-09 |
| A Study of Adipose Tissue in Adaptive Responses to Exercise (NCT06053125) | Mayo Clinic | 2023-11-09 |
| MEDI5752 in Combination With Carboplatin Plus Pemetrexed in Unresectable Pleural Mesothelioma (NCT06097728) | AstraZeneca | 2023-11-09 |
| Home OCT-Guided Treatment Versus Treat and Extend for the Management of Neovascular AMD (NCT05904028) | Jaeb Center for Health Research | 2023-11-09 |
| Study of KITE-197 in Participants With Relapsed or Refractory Large B-cell Lymphoma (NCT06079164) | Kite, A Gilead Company | 2023-11-09 |
| Effects of a Widely Used Vaccine Adjuvant in Subjects With Early Alzheimer's Disease Double-blind Study to Assess the Safety and Efficacy of AD04 in Patients With Early Alzheimer's Disease - ADVANCE (NCT07107074) | ADvantage Therapeutics | 2023-11-08 |
| Permanent Intracranial Stenting for Acute Ischemic Stroke Related to a Refractory Large Vessel Occlusion (NCT06071091) | Assistance Publique - Hôpitaux de Paris | 2023-11-08 |
| LSD Occupancy of the Serotonin 2A Receptor in the Human Brain (NCT05953038) | Rigshospitalet, Denmark | 2023-11-08 |
| Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma (NCT06056895) | University of Washington | 2023-11-08 |
| Overtaking Intra and Inter Tumoral Heterogeneity In Von Hippel-Lindau Related Renal Cancer (NCT06195150) | IRCCS San Raffaele | 2023-11-08 |
| Testing the Safety of Giving a Standard Dose of Radiation Over a Shorter Period of Time for Patients Who Had Surgery for Intermediate-Risk Head and Neck Cancer (NCT05540899) | American College of Radiology | 2023-11-08 |
| A Randomised, Phase 3 Non-inferiority Study of DOR/3TC/TDF Compared to DTG/TAF/FTC in Participants Infected With HIV-1 Starting First-line Antiretroviral Therapy (NCT05924438) | Professor Francois Venter | 2023-11-08 |
| A 104-Week Study of Ritlecitinib Oral Capsules in Adults With Nonsegmental Vitiligo (Active and Stable) Tranquillo 2 (NCT06072183) | Pfizer | 2023-11-08 |
| Bipolar Disorder Integrative Staging: Incorporating Biomarkers Into Progression Across Stages (NCT07343739) | ASST Fatebenefratelli Sacco | 2023-11-08 |
| Addressing Unmet Social Needs Among Hospitalized Children (NCT05968716) | University of California, San Francisco | 2023-11-08 |
| A Neoadjuvant Study of Tislelizumab and SX-682 for Resectable Pancreas Cancer (NCT05604560) | Lei Zheng | 2023-11-08 |
| Determine Effectiveness of Anifrolumab In SYstemic Sclerosis (DAISY) (NCT05925803) | AstraZeneca | 2023-11-08 |
| Dental Implant Stability Placed in Healed Bony Sites Using Oversized Drilling Versus Conventional Drilling Protocol (NCT06917638) | Cairo University | 2023-11-08 |
| The Epidemiology Change From 2006 to 2022 of Infective Endocarditis in Taiwan (NCT07156292) | National Taiwan University Hospital | 2023-11-08 |
| Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour Disorder (NCT05904717) | Syntara | 2023-11-08 |
| A Study Evaluating the Effect of Frozen-Section Directed Excision Surgery on Vulvar Dysplasia (NCT05934851) | Wake Forest University Health Sciences | 2023-11-07 |
| Intratumoral PH-762 for Cutaneous Carcinoma (NCT06014086) | Phio Pharmaceuticals Inc. | 2023-11-07 |
| Physiotherapist Supervised Training in Patients With Anterior Shoulder Instability (NCT06033157) | Hvidovre University Hospital | 2023-11-07 |
| Study to Investigate Efficacy, Safety, and Tolerability of Zibotentan/Dapagliflozin Compared to Dapagliflozin in Participants With Chronic Kidney Disease and High Proteinuria (ZENITH High Proteinuria) (NCT06087835) | AstraZeneca | 2023-11-07 |
| Psychoeducation for Uveal Melanoma (NCT06075589) | Jonsson Comprehensive Cancer Center | 2023-11-07 |