| Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676) (NCT03711032) | Merck Sharp & Dohme LLC | 2018-12-24 |
| Clinico-biological Data Collection Study of Metastatic Breast Cancer (NCT03958136) | Institut Cancerologie de l'Ouest | 2018-12-24 |
| A Cohort Study of the Intestinal Microbiota of Premature Infants (NCT03717584) | University of California, Davis | 2018-12-23 |
| Pharmacokinetics of IFX and TNF Concentrations in Serum, Stool, and Colonic Mucosa in Acute Severe Ulcerative Colitis (NCT03765450) | Alimentiv Inc. | 2018-12-21 |
| Study of Durvalumab+Olaparib or Durvalumab After Treatment With Durvalumab and Chemotherapy in Patients With Lung Cancer (ORION) (NCT03775486) | AstraZeneca | 2018-12-21 |
| A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC (NCT03661866) | Target PharmaSolutions, Inc. | 2018-12-21 |
| A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer (NCT03742102) | AstraZeneca | 2018-12-21 |
| Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas (NCT03038672) | National Cancer Institute (NCI) | 2018-12-21 |
| Study of an Immunotherapeutic, DPX-Survivac, in Combination With Low Dose Cyclophosphamide & Pembrolizumab, in Subjects With Selected Advanced & Recurrent Solid Tumors (NCT03836352) | ImmunoVaccine Technologies, Inc. (IMV Inc.) | 2018-12-21 |
| Grey Matter Damage at the Earliest Phase of Multiple Sclerosis : a Longitudinal 7T MRI Study (NCT03659981) | Assistance Publique Hopitaux De Marseille | 2018-12-20 |
| An Intervention to Help Patients and Caregivers Manage Stress and Improve Communication Skills When Talking About Cancer (NCT03794635) | Memorial Sloan Kettering Cancer Center | 2018-12-20 |
| Investigate the Contribution of Ipatasertib to Neoadjuvant Chemotherapy Plus Atezolizumab in TNBC (NCT05498896) | Queen Mary University of London | 2018-12-19 |
| Evaluation of the Safety and Efficacy of the Association of Ibrutinib and Daratumumab in Relapsed/Refractory Chronic Lymphocytic Leukemia With p53 Dysfunction (NCT03734198) | French Innovative Leukemia Organisation | 2018-12-19 |
| MT2017-45: CAR-T Cell Therapy for Heme Malignancies (NCT03642626) | Masonic Cancer Center, University of Minnesota | 2018-12-18 |
| Span-C-SBRT for Pancreatic Cancer (NCT03505229) | Royal North Shore Hospital | 2018-12-18 |
| A Study to Evaluate the Long-term Safety and Tolerability of Lucerastat in Adult Subjects With Fabry Disease (NCT03737214) | Idorsia Pharmaceuticals Ltd. | 2018-12-18 |
| Resorbable vs Non-resorbable Bone Substitute at Immediate Post-extractive Single Implants (NCT07047131) | Marco Esposito | 2018-12-18 |
| Local Consolidative Therapy and Brigatinib in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (NCT03707938) | M.D. Anderson Cancer Center | 2018-12-18 |
| Patch vs. No Patch Fetoscopic Meningomyelocele Repair Study (NCT03794011) | Baylor College of Medicine | 2018-12-18 |
| Choroidal Response to Novel Spectacle Lens to Control Myopia Progression (NCT03818880) | SightGlass Vision, Inc. | 2018-12-18 |
| Post-Market Registry of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis Implanted in Peripheral Vessels (NCT03720704) | W.L.Gore & Associates | 2018-12-18 |
| Study of Pembrolizumab Given Prior to Surgery and in Combination With Radiotherapy Given Post-surgery for Advanced Head and Neck Squamous Cell Carcinoma (MK-3475-689) (NCT03765918) | Merck Sharp & Dohme LLC | 2018-12-17 |
| Impact of the Use of Remote Monitoring in the Follow-up of the Renal Transplant Patient. (NCT03750331) | Centre Hospitalier Universitaire de Saint Etienne | 2018-12-17 |
| Shorter Course, Hypofractionated Pre-Surgery Radiation Therapy in Treating Patients With Localized, Resectable Soft Tissue Sarcoma of the Extremity of Superficial Trunk (NCT03819985) | M.D. Anderson Cancer Center | 2018-12-17 |
| Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Patients With Pediatric Solid Tumors (GAP) (NCT02932956) | Baylor College of Medicine | 2018-12-17 |
| Danish Trial of Beta Blocker Treatment After Myocardial Infarction Without Reduced Ejection Fraction (NCT03778554) | Bispebjerg Hospital | 2018-12-17 |
| Study of CVM-1118 for Patients With Advanced Neuroendocrine Tumors (NCT03600233) | TaiRx, Inc. | 2018-12-15 |
| Daratumumab, VELCADE (Bortezomib), Lenalidomide and Dexamethasone Compared to VELCADE, Lenalidomide and Dexamethasone in Subjects With Previously Untreated Multiple Myeloma (NCT03710603) | Stichting European Myeloma Network | 2018-12-14 |
| Tramadol Versus Placebo and Morphine in the Management of Post-Operative Pain Abdominoplasty (NCT03774836) | Avenue Therapeutics, Inc. | 2018-12-14 |
| CPX-351 (Vyxeos™) for Transplant Eligible, Higher Risk Patients With Myelodysplastic Syndrome (NCT03572764) | Washington University School of Medicine | 2018-12-14 |
| Atezolizumab After Chemo-radiotherapy for MIBC Patients Not Eligible for Radical Cystectomy (NCT03697850) | UNICANCER | 2018-12-14 |
| The RADIANCE II Pivotal Study: A Study of the ReCor Medical Paradise System in Stage II Hypertension (NCT03614260) | ReCor Medical, Inc. | 2018-12-14 |
| Irinotecan-based Triplet (FOLFOXIRI) as Perioperative Treatment in Resectable Gastric and Gastroesophageal Junction Adenocarcinoma. (NCT03773367) | Lund University Hospital | 2018-12-14 |
| Metacognition in Neurological Injury (NCT03752697) | University of Nebraska Lincoln | 2018-12-13 |
| Foods Within a Meal and Food Liking Study (NCT03783507) | The University of Tennessee, Knoxville | 2018-12-13 |
| VX15/2503 With or Without Ipilimumab and/or Nivolumab in Patients With Resectable Stage IIIB-D Melanoma (NCT03769155) | Emory University | 2018-12-13 |
| A Study of the Safety and Activity of Liposomal Irinotecan in Combination With the 5-FU and Oxaliplatin in the Preoperative Treatment of Pancreatic Adenocarcinoma (NCT03483038) | University of Florida | 2018-12-13 |
| Multi-antigen T Cell Infusion Against Neuro-oncologic Disease (NCT03652545) | Catherine Bollard | 2018-12-12 |
| Predictive Markers of Immune-related Adverse Events in Patients Treated With Immune Stimulatory Drugs (NCT03984318) | Gustave Roussy, Cancer Campus, Grand Paris | 2018-12-12 |
| Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated, Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002) (NCT03742895) | Merck Sharp & Dohme LLC | 2018-12-12 |
| Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17 (NCT03755804) | St. Jude Children's Research Hospital | 2018-12-12 |
| Prostate Cancer Monitoring Using [18F]DCFPyL and Blood Based Biomarkers (NCT03585114) | Columbia University | 2018-12-11 |
| QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors (NCT03228667) | ImmunityBio, Inc. | 2018-12-11 |
| A Study of the Effect and Safety of Sparsentan in the Treatment of Patients With IgA Nephropathy (NCT03762850) | Travere Therapeutics, Inc. | 2018-12-11 |
| Probiotics to Prevent Relapse After Hospitalization for Bipolar Depression (NCT03349528) | Sheppard Pratt Health System | 2018-12-11 |
| NK Cell Deregulation in HBV Patients (NCT03761875) | University Hospital, Limoges | 2018-12-11 |
| OCS™ Lung TOP Registry For Donor Lungs for Transplantation (NCT03639025) | TransMedics | 2018-12-10 |
| Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations (NCT03609216) | Alliance for Clinical Trials in Oncology | 2018-12-10 |
| Sleep Profiles in REM Sleep Behavior Disorder (NCT04886076) | Massachusetts General Hospital | 2018-12-07 |
| A Trial to Evaluate Efficacy and Safety of Ribociclib With Endocrine Therapy as Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer (NCT03701334) | Novartis Pharmaceuticals | 2018-12-07 |
| Adavosertib With or Without Olaparib in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer (NCT03579316) | M.D. Anderson Cancer Center | 2018-12-07 |
| SPECT/CT for the Characterization of Renal Masses (NCT03996850) | Jonsson Comprehensive Cancer Center | 2018-12-07 |
| Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapy (NCT03670056) | Yale University | 2018-12-06 |
| A Study of Neoadjuvant/Adjuvant Durvalumab for the Treatment of Patients With Resectable Non-small Cell Lung Cancer (NCT03800134) | AstraZeneca | 2018-12-06 |
| Study of Adagloxad Simolenin (OBI-822)/OBI-821 in the Adjuvant Treatment of Patients With Globo H Positive TNBC (NCT03562637) | OBI Pharma, Inc | 2018-12-05 |
| The Effect of Enhanced Recovery After Surgery (ERAS) in Gastric Cancer Surgery (NCT06209983) | National Taiwan University Hospital | 2018-12-05 |
| Digitally-Captured Step Counts for Evaluating Performance Status in Advanced Cancer Patients (NCT03757182) | Cedars-Sinai Medical Center | 2018-12-05 |
| Comparison of Intermittent Androgen Deprivation Therapy With or Without Irradiation Recovery in Prostate Cancer Patients (NCT03630666) | Institut Cancerologie de l'Ouest | 2018-12-04 |
| 1st Line Durvalumab in PS 2 NSCLC Patients (NCT03620669) | Swiss Cancer Institute | 2018-12-04 |
| Prevention of Celiac Disease in Skåne (NCT03562221) | Lund University | 2018-12-04 |
| Dietary Management of Gestational Diabetes (NCT03681054) | Helsinki University Central Hospital | 2018-12-03 |
| TITRE III: Influenza B Immunogenicity Investigation (NCT03753347) | British Columbia Centre for Disease Control | 2018-12-01 |
| Immune Profile of Saliva and Serum of Patients With Primary Sjögren´s Syndrome (NCT03711214) | University of Sao Paulo General Hospital | 2018-12-01 |
| Factors Affecting Newborn Body Composition and Later Health in Helsinki Birth Cohort 2018-2022 (NCT03765684) | Helsinki University Central Hospital | 2018-12-01 |
| Screening for Asymptomatic Coronary Artery Disease in Kidney Transplant Candidates (NCT03674307) | University of British Columbia | 2018-12-01 |
| Investigation Into an Innovative, Clinical Slip Inducing Device in the Chronic Incomplete Spinal Cord Population (NCT03744286) | Shirley Ryan AbilityLab | 2018-12-01 |
| A Global Study to Evaluate Transarterial Chemoembolization (TACE) in Combination With Durvalumab and Bevacizumab Therapy in Patients With Locoregional Hepatocellular Carcinoma (NCT03778957) | AstraZeneca | 2018-11-30 |
| Feasibility Study of MET-4: Evaluating Fecal Microbiome Effects in Immunotherapy Patients (NCT03686202) | University Health Network, Toronto | 2018-11-30 |
| Edwards PASCAL CLASP IID/IIF Pivotal Clinical Trial (NCT03706833) | Edwards Lifesciences | 2018-11-30 |
| Peer Approaches to Lupus Self-management (NCT03734055) | Medical University of South Carolina | 2018-11-30 |
| NOVOCART 3D Treatment Following Microfracture Failure (NCT03219307) | Aesculap Biologics, LLC | 2018-11-30 |
| TReatment of Pulmonary Hypertension Group II Study (NCT03611270) | SoniVie Inc. | 2018-11-30 |
| Comparative Antiresorptive Efficacy Discontinuation of Denosumab (NCT03623633) | Massachusetts General Hospital | 2018-11-30 |
| Atezolizumab and Cobimetinib in Treating Patients With Metastatic, Recurrent, or Refractory Non-small Cell Lung Cancer (NCT03600701) | National Cancer Institute (NCI) | 2018-11-29 |
| Cognitive Behavioral Therapy in Helping Patients With Acute Myeloid Leukemia or Lymphoma With Cancer-Related Fatigue (NCT03747757) | M.D. Anderson Cancer Center | 2018-11-29 |
| A Study of Zolbetuximab (IMAB362) Plus CAPOX Compared With Placebo Plus CAPOX as First-line Treatment of Subjects With Claudin (CLDN) 18.2-positive, HER2-negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma (GLOW). (NCT03653507) | Astellas Pharma Global Development, Inc. | 2018-11-28 |
| Vaginal Microbiome Exposure and Immune Responses in C-section Infants (NCT03567707) | National Institute of Allergy and Infectious Diseases (NIAID) | 2018-11-28 |
| Brentuximab Vedotin and Nivolumab in Treating Patients With Early Stage Classic Hodgkin Lymphoma (NCT03712202) | City of Hope Medical Center | 2018-11-28 |
| Post-Authorization Long-Term Safety Study of LUTATHERA (NCT03691064) | Advanced Accelerator Applications | 2018-11-28 |
| CD19-specific CAR T Cells With a Fully Human Binding Domain for CD19+ Leukemia or Lymphoma (NCT03684889) | Seattle Children's Hospital | 2018-11-28 |
| HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases (NCT03696030) | City of Hope Medical Center | 2018-11-27 |
| Savolitinib in Treating Patients With Recurrent or Refractory Primary CNS Tumors (NCT03598244) | National Cancer Institute (NCI) | 2018-11-27 |
| Validation of a Novel Smartphone-based Method for Heart Rhythm Monitoring in the Home Environment (NCT04300270) | Karolinska Institutet | 2018-11-27 |
| A Study of Durvalumab as Consolidation Therapy in Non-Small Cell Lung Cancer Patients (NCT03706690) | AstraZeneca | 2018-11-27 |
| Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung Cancer (NCT03637816) | M.D. Anderson Cancer Center | 2018-11-27 |
| Preventing Asthma in High Risk Kids (NCT02570984) | Boston Children's Hospital | 2018-11-27 |
| Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma (NCT03646617) | Abramson Cancer Center at Penn Medicine | 2018-11-27 |
| Pyloroplasty Versus No Pyloroplasty in Patients Undergoing Esophagectomy (NCT03740542) | University of Pittsburgh | 2018-11-27 |
| Personalized Exercise Oncology (NCT04328038) | University Hospital Heidelberg | 2018-11-26 |
| A Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib (LY2835219) in Participants With Prostate Cancer (NCT03706365) | Eli Lilly and Company | 2018-11-26 |
| Multi-Center Study of GSK2857916 in Combination With Pomalidomide and Dex (NCT03715478) | Canadian Myeloma Research Group | 2018-11-26 |
| MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM) (NCT03853616) | Miltenyi Biomedicine GmbH | 2018-11-26 |
| Obinutuzumab in Marginal Zone Lymphoma (NCT03322865) | Christian Buske | 2018-11-23 |
| Safety and Efficacy of the ANTHEM™ CR Total Knee System (NCT03885622) | Smith & Nephew Pte Ltd | 2018-11-23 |
| A Comparison of Reduced Dose Total Body Irradiation (TBI) and Cyclophosphamide With Fludarabine and Melphalan Reduced Intensity Conditioning in Adults With Acute Lymphoblastic Leukaemia (ALL) in Complete Remission. (ALL-RIC) (NCT03821610) | University of Birmingham | 2018-11-22 |
| Project HOPE 1000: Health Outcomes Pregnancy Exposures (NCT04417283) | Duke University | 2018-11-21 |
| Enzalutamide With or Without Radium Ra 223 Dichloride in Patients With Metastatic, Castration-Resistant Prostate Cancer (NCT03344211) | University of Southern California | 2018-11-21 |
| OPTIMIZE Sirolimus-Eluting Coronary Stent Systems Pharmacokinetics (PK) Study (NCT03716102) | Svelte Medical Systems, Inc. | 2018-11-21 |
| Healing Osteoarthritic Joints in the Wrist With Adult ADRCs (NCT03503305) | InGeneron, Inc. | 2018-11-21 |
| Use of Multiparametric MRI in the Management of Head and Neck Cancer: a Prospective Analysis (NCT03993665) | AZ Sint-Jan AV | 2018-11-20 |