| SLeep and OPioid UsE in Patients Undergoing Total Knee Arthroplasty (NCT04247646) | Scripps Health | 2020-10-01 |
| Circulating Tumour DNA (ctDNA) as a Prognostic and Predictive Marker in Colorectal Cancer - a Pilot Study (NCT04726800) | Anna Martling | 2020-10-01 |
| KT Tape for Pediatric Clavicle Fractures (NCT04161534) | University of Alabama at Birmingham | 2020-10-01 |
| Comparison of Dimensional Changes After Tooth Extractions Between Xenograft and Allograft (NCT04550689) | UConn Health | 2020-10-01 |
| Burden of Disease and Functional Impairment in XLH (NCT04946409) | Wuerzburg University Hospital | 2020-10-01 |
| Less Frequent IV Dosing & Tumor Microenvironment (TME) Study of Nemvaleukin Alfa (ALKS 4230) Monotherapy and in Combination With Pembrolizumab (ARTISTRY-3) (NCT04592653) | Mural Oncology, Inc | 2020-09-30 |
| Infinity-Swedeheart Registry Based Randomized Clinical Trial (R-RCT) (NCT04562805) | Elixir Medical Corporation | 2020-09-30 |
| Study Comparing Intravenous (IV)/Subcutaneous (SC) Risankizumab to IV/SC Ustekinumab to Assess Change in Crohn's Disease Activity Index (CDAI) in Adult Participants With Moderate to Severe Crohn's Disease (CD) (NCT04524611) | AbbVie | 2020-09-30 |
| Stem Cell Therapy for Limbal Stem Cell Deficiency (NCT03957954) | University of California, Los Angeles | 2020-09-30 |
| A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Crovalimab Versus Eculizumab in Participants With Paroxysmal Nocturnal Hemoglobinuria (PNH) Currently Treated With Complement Inhibitors (NCT04432584) | Hoffmann-La Roche | 2020-09-30 |
| Bioclinical Evaluation of 2 Biomarkers of Aviremic HIV-1 in CD4+ T Cells of Adults Undergoing Treatment (NCT03940521) | Centre Hospitalier Universitaire de Nīmes | 2020-09-30 |
| The Optimising Isolation, Quarantine and Distancing Study for COVID-19 (NCT07337382) | Macfarlane Burnet Institute for Medical Research and Public Health Ltd | 2020-09-30 |
| Long-Term Outcomes After the Multisystem Inflammatory Syndrome in Children (NCT05287412) | Carelon Research | 2020-09-30 |
| ROSE-Longitudinal Assessment With Neuroimaging (NCT05089331) | State University of New York at Buffalo | 2020-09-30 |
| A Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NCT04487080) | Janssen Research & Development, LLC | 2020-09-30 |
| Optimal Timing of Transcatheter Aortic Valve Implantation and Percutaneous Coronary Intervention - The TAVI PCI Trial (NCT04310046) | University of Zurich | 2020-09-30 |
| Mesothelin-targeted CAR T-cell Therapy in Patients With Mesothelioma (NCT04577326) | Memorial Sloan Kettering Cancer Center | 2020-09-30 |
| The PREBA Study: Effect of Preoperative Weight Loss With a 14-day Low-calorie Diet on Surgical Procedure and Outcomes in Patients Undergoing RYGB Surgery (NCT04433338) | Rijnstate Hospital | 2020-09-29 |
| Biweekly Actinomycin-D Treatment or Multi-day Methotrexate Protocol in Low-risk Gestational Trophoblastic Neoplasia (NCT04562558) | xiang yang | 2020-09-29 |
| Securing Employment and Economic Keys to Stability for Persons With Disabilities (NCT04394949) | Communication Institute International, Inc. | 2020-09-29 |
| Nasal Decolonization of Dialysis Patients Noses (NCT04210505) | Marin L. Schweizer, PhD | 2020-09-29 |
| Deep Brain Reorienting in Post-traumatic Stress Disorder (NCT04317820) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2020-09-29 |
| A Study Comparing Savolitinib Plus Osimertinib vs Savolitinib Plus Placebo in Patients With EGFRm+ and MET Amplified Advanced NSCLC (NCT04606771) | AstraZeneca | 2020-09-28 |
| A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy (NCT04543617) | Hoffmann-La Roche | 2020-09-28 |
| Step Count Monitoring as a Measure of Physical Activity in Patients With Newly Diagnosed Glioma Undergoing Radiation Therapy (NCT04186832) | M.D. Anderson Cancer Center | 2020-09-28 |
| A Post-market, Observational Registry With the easyEndoTM Universal Linear Cutting Stapler in Laparoscopic Bariatric Surgery (NCT04422236) | Duomed | 2020-09-28 |
| SPRINT: Signature for Pain Recovery IN Teens (NCT04285112) | Stanford University | 2020-09-28 |
| Effect of the SCOT-HEART 2 Trial on Lifestyle. (NCT04156061) | University of Edinburgh | 2020-09-28 |
| Study of AIC100 CAR T Cells in Relapsed/Refractory Thyroid Cancer (NCT04420754) | AffyImmune Therapeutics, Inc. | 2020-09-28 |
| Trial to Shorten Pharmacologic Treatment of Newborns With Neonatal Opioid Withdrawal Syndrome (NOWS) (NCT04214834) | Advancing Clinical Trials in Neonatal Opioid Withdrawal (ACT NOW) Program | 2020-09-28 |
| Esophagogastric Junction Distensibility During Hiatal Hernia Repair (NCT04450628) | Wake Forest University Health Sciences | 2020-09-28 |
| Efficacy and Influencing Factors of Repeated Low-level Red-light in Myopia (NCT07104513) | Ruihua Wei | 2020-09-28 |
| Mechanistic Studies of Nicotinamide Riboside in Human Heart Failure (NCT04528004) | University of Washington | 2020-09-26 |
| Guys/Girls Opt for Activities for Life Trial (GOAL) to Increase Young Adolescents' Physical Activity and Healthy Eating (NCT04213014) | Michigan State University | 2020-09-26 |
| Study of Rituximab or Tocilizumab for Patients With Steroid-Dependent Immune-Related Adverse Events (irAEs) (NCT04375228) | Columbia University | 2020-09-25 |
| A Study of the Efficacy and Safety of Pexidartinib in Adult Subjects With TGCT (NCT04488822) | Daiichi Sankyo Co., Ltd. | 2020-09-25 |
| A Pediatric and Young Adult Trial of Genetically Modified T Cells Directed Against CD22 for Relapsed/Refractory Leukemia or Lymphoma (NCT04571138) | Seattle Children's Hospital | 2020-09-25 |
| Tourniquet-Test in HHT (NCT06266624) | University Hospital, Essen | 2020-09-25 |
| Isa-KRd vs KRd in Newly Diagnosed Multiple Myeloma Patients Eligible for Autologous Stem Cell Transplantation (IsKia TRIAL) (NCT04483739) | European Myeloma Network B.V. | 2020-09-25 |
| Eflornithine (DFMO) and Etoposide for Relapsed/Refractory Neuroblastoma (NCT04301843) | Giselle Sholler | 2020-09-25 |
| BIOFLOW-VIII All-comers Orsiro Mission Safety and Performance Registry (NCT04555174) | Biotronik AG | 2020-09-25 |
| Neoadjuvant Atezolizumab in Cutaneous Melanoma (NCT04020809) | The Methodist Hospital Research Institute | 2020-09-25 |
| Combination of Novel Therapies for CKD Comorbid Depression (NCT04422652) | Stony Brook University | 2020-09-24 |
| Randomized Phase II Trial of Salvage Radiotherapy for Prostate Cancer In 4 Weeks v. 2 Weeks (NCT04422132) | Weill Medical College of Cornell University | 2020-09-24 |
| AAV Gene Therapy Study for Subjects with PKU (NCT04480567) | BioMarin Pharmaceutical | 2020-09-24 |
| Celtra Quatro Crown Study (NCT04604301) | University of Michigan | 2020-09-24 |
| Testing the Addition of an Anti-cancer Drug, Berzosertib, to the Usual Treatment (Radiation Therapy) for Chemotherapy-Resistant Triple-Negative and Estrogen and/or Progesterone Receptor Positive, HER2 Negative Breast Cancer (NCT04052555) | National Cancer Institute (NCI) | 2020-09-24 |
| Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) (NCT04526665) | Ipsen | 2020-09-24 |
| Nature and Animal-assisted Activities (NCT06431126) | Kronoberg County Council | 2020-09-24 |
| Oral Azithromycin to Prevent Stillbirths and Infant Mortality in Mali (NCT03909737) | University of Maryland, Baltimore | 2020-09-24 |
| Camrelizumab in Combination With Apatinib in Patients With Radioactive Iodine-refractory Differentiated Thyroid Cancer (NCT04560127) | Peking Union Medical College Hospital | 2020-09-23 |
| Improving Early Detection of Melanoma Recurrence With Circulating Tumor DNA (ctDNA) (NCT05736523) | University of Utah | 2020-09-23 |
| Targeted Agent Evaluation in Digestive Cancers in China Based on Molecular Characteristics (NCT04584008) | Peking University | 2020-09-23 |
| Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors (NCT04557449) | Pfizer | 2020-09-23 |
| Sacituzumab Govitecan +/- Pembrolizumab In HR+ / HER2 - MBC (NCT04448886) | Ana C Garrido-Castro, MD | 2020-09-23 |
| A Study of Niraparib in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for the Treatment of Participants With Deleterious Germline or Somatic Homologous Recombination Repair (HRR) Gene-Mutated Metastatic Castration-Sensitive Prostate Cancer (mCSPC) (NCT04497844) | Janssen Research & Development, LLC | 2020-09-23 |
| Window of Opportunity Study of Pembrolizumab Alone and in Combinations in Bladder Cancer (NCT03978624) | UNC Lineberger Comprehensive Cancer Center | 2020-09-23 |
| Choosing Ovarian Preservation or Removal Before Surgery for Endometrial Cancer (NCT04569773) | Memorial Sloan Kettering Cancer Center | 2020-09-23 |
| Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium (NCT04060017) | Southwest Autism Research & Resource Center | 2020-09-22 |
| Physiopathology and Sequelae of COVID-19 Infection (NCT04563676) | Centre Hospitalier Universitaire, Amiens | 2020-09-22 |
| Multivessel TALENT (NCT04390672) | National University of Ireland, Galway, Ireland | 2020-09-22 |
| Radium-223 in Biochemically Recurrent Prostate Cancer (NCT04206319) | National Cancer Institute (NCI) | 2020-09-22 |
| Identification and Characterization of SARS-CoV-2 Specific CD8 T Cells in Humans (NCT04565067) | National Institute on Aging (NIA) | 2020-09-22 |
| NKX101, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS (NCT04623944) | Nkarta, Inc. | 2020-09-21 |
| Open Nipple Sparing Mastectomy (NSM) (NCT04447339) | Intuitive Surgical | 2020-09-21 |
| Phase I Trial of DNA-PK Inhibitor (PEPOSERTIB ) in Combination With Radiation and Adjuvant Temozolomide in Newly Diagnosed MGMT Unmethylated and Recurrent Glioblastoma (NCT04555577) | M.D. Anderson Cancer Center | 2020-09-20 |
| A New Parameter for the Assessment of Distance Visual Capacity: the Critical Visual Acuity (CVA) (NCT04632901) | Democritus University of Thrace | 2020-09-20 |
| Mycobacterial Lung Diseases in Virginia: Sequencing and Clinical Determinants of Relapse and Outcome (NCT05277857) | University of Virginia | 2020-09-20 |
| Treatment of COVID-19 by Nebulization of Inteferon Beta 1b Efficiency and Safety Study (NCT04469491) | Centre Hospitalier Universitaire, Amiens | 2020-09-20 |
| A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP, an Autoimmune Disorder That Affects the Peripheral Nerves) (NCT04280718) | argenx | 2020-09-18 |
| Improving Understanding of Brain Tumors Through Preservation of Biologically Active Brain Tissue (NCT04545177) | Case Comprehensive Cancer Center | 2020-09-17 |
| Study of ME-401 in Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin's Lymphoma (NHL) (NCT04533581) | Kyowa Kirin Co., Ltd. | 2020-09-17 |
| A Study of Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma (NCT04557098) | Janssen Research & Development, LLC | 2020-09-17 |
| Patient Response to Immunotherapy Using Spliceosome Mutational Markers (PRISMM) (NCT04447651) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2020-09-17 |
| Effect of Collagen Supplementation on Tendinopathy (NCT04578418) | Bispebjerg Hospital | 2020-09-16 |
| PF-07104091 as a Single Agent and in Combination Therapy (NCT04553133) | Pfizer | 2020-09-16 |
| Efficacy and Safety of SOX Regimen Combined With Camrelizumab as Neoadjuvant Treatment in Locally Advanced Gastric Cancer: a Phase II, Single-arm Study (NCT05602935) | The Second Affiliated Hospital of Fujian Medical University | 2020-09-16 |
| Study to Evaluate Loncastuximab Tesirine With Rituximab Versus Immunochemotherapy in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (NCT04384484) | ADC Therapeutics S.A. | 2020-09-16 |
| Chemo-Radiotherapy Boost Treatment Guided by Perfusion MRI on Hypoxic Zones in Head and Neck Cancer (NCT06880289) | Regina Elena Cancer Institute | 2020-09-16 |
| Study of Nivolumab in Combination w Radium-223 in Men w Metastatic Castration Resistant Prostate Cancer (NCT04109729) | University of Utah | 2020-09-16 |
| Supportive Oncology Care At Home RCT (NCT04544046) | Massachusetts General Hospital | 2020-09-16 |
| Social & Contextual Impact on Children Undergoing Liver Transplantation (NCT04551742) | University of California, San Francisco | 2020-09-16 |
| YES Study - Newly Diagnosed/Metastatic Intervention (NCT04379414) | Dana-Farber Cancer Institute | 2020-09-16 |
| Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC (NCT04140526) | OncoC4, Inc. | 2020-09-16 |
| A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors (NCT04503278) | BioNTech Cell & Gene Therapies GmbH | 2020-09-16 |
| Natural Versus Programmed Frozen Embryo Transfer (NatPro) (NCT04551807) | JHSPH Center for Clinical Trials | 2020-09-16 |
| Combined Y-90 Selective Internal Radiation Therapy (Y-90 SIRT) and Stereotactic Body Radiation Therapy (SBRT) in Hepatic Malignancy. (NCT04518748) | University of Michigan Rogel Cancer Center | 2020-09-16 |
| Virtual E-health System for Pacemakers (NCT03636230) | Ratika Parkash | 2020-09-15 |
| Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in Subjects With Advanced or Metastatic Non-Small Cell Lung Cancer (TROPION-Lung02) (NCT04526691) | Daiichi Sankyo | 2020-09-15 |
| Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study (NCT04316117) | ECOG-ACRIN Cancer Research Group | 2020-09-15 |
| Tucatinib Plus Trastuzumab and Oxaliplatin-based Chemotherapy or Pembrolizumab-containing Combinations for HER2+ Gastrointestinal Cancers (NCT04430738) | Seagen, a wholly owned subsidiary of Pfizer | 2020-09-15 |
| No Axillary sUrgical Treatment In Clinically Lymph Node Negative Patients After UltraSonography (NCT04303715) | Seoul National University Hospital | 2020-09-15 |
| Alterations of the Microbiome During Critical Illness With Short and Long Term Clinical Outcomes (NCT04552834) | University of Chicago | 2020-09-15 |
| Reconnecting to Ourselves and Others in Virtual Meetings (ROOM) (NCT06360562) | Massachusetts General Hospital | 2020-09-15 |
| Acetyl Salicylic Elimination Trial JAPAN: The ASET JAPAN Pilot Study (NCT05117866) | Meditrix Corp | 2020-09-15 |
| Evaluation of the Quality of Care in the Emergency Department by Studying the Appropriateness of Admissions of Patients Accessing the Emergency Department (Fondazione IRCCS Ca' Granda Ospedale Maggione Policlinico) (NCT06345352) | Mario Negri Institute for Pharmacological Research | 2020-09-15 |
| ADI-PEG 20 Plus Radiotherapy and Temozolomide in Subjects With Glioblastoma Multiforme (NCT04587830) | Polaris Group | 2020-09-14 |
| Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy (NCT04305613) | Abramson Cancer Center at Penn Medicine | 2020-09-14 |
| Improved Diagnostics and Monitoring of Polymyalgia Rheumatica (NCT04519580) | Kresten Krarup Keller | 2020-09-14 |
| Serial Brain MRI in Hospitalized Preterm Infants (NCT06052865) | Brigham and Women's Hospital | 2020-09-14 |