| Lung Structure-Function In Survivors of Mild and Severe COVID-19 Infection (NCT04584671) | Western University, Canada | 2021-01-01 |
| Glutamatergic Mechanisms of Psychosis and Target Engagement (SA1) (NCT04589208) | New York State Psychiatric Institute | 2021-01-01 |
| Neurofeedback to Improve Working Memory in Mild Cognitive Impairment (NCT04566900) | University of California, San Diego | 2021-01-01 |
| Robotic Versus Laparoscopic Surgery for Middle and Low Rectal Cancer: a Target Trial Emulation (NCT06814093) | Xu jianmin | 2021-01-01 |
| Couples' QOL in Metastatic Breast Cancer (NCT05636943) | Fox Chase Cancer Center | 2021-01-01 |
| RegiStry Of the multiFaceted medIcal cenTer (NCT06803862) | National Medical Research Center for Therapy and Preventive Medicine | 2021-01-01 |
| Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL) (NCT04385277) | Children's Oncology Group | 2020-12-31 |
| Effectiveness and Safety of Dabrafenib in Combination With Trametinib as Adjuvant Treatment for Chinese Patients With Stage III BRAF V600 Mutation-positive Melanoma After Complete Resection (NCT04666272) | Novartis Pharmaceuticals | 2020-12-31 |
| Pembrolizumab, IRX-2, and Chemotherapy in Triple Negative Breast Cancer (NCT04373031) | Providence Health & Services | 2020-12-30 |
| Investigation of Surgery, Collagenase, and Restorex for the Improvement of Peyronie's (NCT04786106) | Charitable Union for the Research and Education of Peyronie's Disease | 2020-12-30 |
| A Study of Risk Factors for the COVID-19 Virus Infection (NCT04697927) | Memorial Sloan Kettering Cancer Center | 2020-12-30 |
| A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations (NCT04639219) | AstraZeneca | 2020-12-30 |
| Pivotal 1 Study of ABBV-RGX-314 (Also Known as RGX-314) Gene Therapy Administered Via Subretinal Delivery One Time in Participants With nAMD (NCT04704921) | AbbVie | 2020-12-29 |
| Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer (NCT04592237) | M.D. Anderson Cancer Center | 2020-12-29 |
| MYLUNG Consortium Study Protocol 2 (NCT05644808) | US Oncology Research | 2020-12-29 |
| CLL Induction Treatment With Venetoclax and Ibrutinib, Followed by Ibrutinib and Obinutuzumab in Patients With MRD. (NCT04639362) | Stichting Hemato-Oncologie voor Volwassenen Nederland | 2020-12-29 |
| Biomarker Monitoring of Prostate Cancer Patients With RSI MRI (ProsRSI) (NCT04349501) | University of California, San Diego | 2020-12-29 |
| Evolutionary Therapy for Rhabdomyosarcoma (NCT04388839) | H. Lee Moffitt Cancer Center and Research Institute | 2020-12-29 |
| Study of RP3 Monotherapy and RP3 in Combination With Nivolumab in Patients With Solid Tumours (NCT04735978) | Replimune, Inc. | 2020-12-29 |
| COVICI-SURV: COVID-19 Vaccination Around ICI Start and Survival (NCT07729241) | Groupe Hospitalier Pitie-Salpetriere | 2020-12-28 |
| RCT Comparing Non-operative vs Operative Treatment of Suprasyndesmotic Ankle Fractures. (NCT04615650) | Sykehuset Innlandet HF | 2020-12-28 |
| The Efficacy of Upper Limb Rehabilitation With Exoskeleton in Patients With Subacute Stroke. (NCT04697368) | IRCCS San Raffaele Roma | 2020-12-28 |
| Comparison of Complication Rates Between Initial and Re-operative Anterior Lumbar Interbody Fusion Surgery: Is There a Difference? (NCT05945550) | Methodist Health System | 2020-12-28 |
| A Phase 1b/2 Study of T-DXd Combinations in HER2-positive Metastatic Breast Cancer (NCT04538742) | AstraZeneca | 2020-12-28 |
| Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma (NCT04417660) | National Cancer Institute (NCI) | 2020-12-26 |
| Guo's Subclavian Artery Reconstruction: The Prospective, Multiple Center Study of WeFlow-Tbranch Stent Graft System(GUEST Study) (NCT04765605) | Hangzhou Endonom Medtech Co., Ltd. | 2020-12-25 |
| A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden (NCT04145115) | National Cancer Institute (NCI) | 2020-12-24 |
| A Post-treatment Program to Identify and Manage Complications Related to Oncology or Hematology Treatments in Cancer Survivors. (NCT04671693) | Centre Leon Berard | 2020-12-24 |
| Intracavitary Carrier-embedded Cs131 Brachytherapy for Recurrent Brain Metastases: a Randomized Phase II Study (NCT04690348) | Memorial Sloan Kettering Cancer Center | 2020-12-24 |
| Pullback Pressure Gradient (PPG) Global Registry (NCT04789317) | VZW Cardiovascular Research Center Aalst | 2020-12-23 |
| Bioavailability and Practicability of Envarsus Versus Advagraf in Liver Transplant Recipients (NCT04720326) | Edward Geissler | 2020-12-23 |
| Characteristics of Pulmonary Vascular Changes in Patients With Kidney Transplantation (NCT04842591) | Medical University of Graz | 2020-12-23 |
| PreOperative Endocrine Therapy for Individualised Care With Abemaciclib (NCT04584853) | Institute of Cancer Research, United Kingdom | 2020-12-23 |
| Single-incision Versus Retropubic Mid-Urethral Sling (Solyx) for SUI During Minimally Invasive Sacrocolpopexy (NCT04586166) | Wake Forest University Health Sciences | 2020-12-23 |
| "QUAD SHOT" Radiotherapy With Pembrolizumab in Patients With Recurrent Head & Neck Cancer (NCT04373642) | University of Oklahoma | 2020-12-23 |
| Efficacy and Safety of Pemafibrate for Nonalcoholic Fatty Liver Disease (NCT06623539) | Yokohama City University | 2020-12-23 |
| Hybrid Functional Electrical Stimulation Exercise to Prevent Cardiopulmonary Declines in High-level Spinal Cord Injury (NCT04458324) | Spaulding Rehabilitation Hospital | 2020-12-22 |
| Surveys, Blood Testing, and Fibroscan in Screening for Liver Fibrosis and Liver Cirrhosis (NCT04785534) | M.D. Anderson Cancer Center | 2020-12-22 |
| Essential Oils for Electrocautery (NCT04260867) | Northwestern University | 2020-12-22 |
| Patient Considerations of Social Media Account Management After Death (NCT05035667) | M.D. Anderson Cancer Center | 2020-12-22 |
| A Study of DS-6000a in Subjects With Advanced Renal Cell Carcinoma and Ovarian Tumors (NCT04707248) | Daiichi Sankyo | 2020-12-22 |
| FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease (NCT04583878) | University of Texas Southwestern Medical Center | 2020-12-22 |
| PEmbRolizumab verSus chEmotherapy and pEmbrolizumab in Non-small-cell Lung Cancers (NSCLC) With PDL1 ≥ 50 % (NCT04547504) | University Hospital, Brest | 2020-12-22 |
| Safety And Efficacy Of TKI Cessation For CML Patients With Stable Molecular Response In A Real World Population (NCT04626024) | Baylor College of Medicine | 2020-12-22 |
| Evaluating Innovative Technologies and Approaches to Addressing Cervical Cancer in Gaza and Maputo Cidade Provinces in Mozambique (NCT05359016) | M.D. Anderson Cancer Center | 2020-12-22 |
| A Study in Participants With First-Line Nivolumab Plus Ipilimumb Therapy Combined With Two Cycles of Chemotherapy for Metastatic Non-Small Cell Lung Cancer (NCT04794010) | Bristol-Myers Squibb | 2020-12-22 |
| An Open-label Study Using ASP-1929 Photoimmunotherapy in Combination With Anti-PD1 Therapy in EGFR Expressing Advanced Solid Tumors (NCT04305795) | Rakuten Medical, Inc. | 2020-12-21 |
| A Study of Avutometinib (VS-6766) v. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer With and Without a KRAS Mutation (NCT04625270) | Verastem, Inc. | 2020-12-21 |
| Study of Immune Globulin Intravenous (Human) GC5107 in Pediatric Subjects With Primary Humoral Immunodeficiency (NCT04565015) | GC Biopharma Corp | 2020-12-21 |
| A Study of Encorafenib Plus Cetuximab With or Without Chemotherapy in People With Previously Untreated Metastatic Colorectal Cancer (NCT04607421) | Pfizer | 2020-12-21 |
| International Post Market Surveillance Study of Intracranial Aneurysms Treated With an Endovascular Approach (NCT04572230) | Stryker Neurovascular | 2020-12-21 |
| Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell Lung Cancer (NCT04665856) | Hoffmann-La Roche | 2020-12-21 |
| A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers (NCT04626635) | Regeneron Pharmaceuticals | 2020-12-21 |
| Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer With or Without Actionable Genomic Alterations (TROPION-LUNG01) (NCT04656652) | Daiichi Sankyo | 2020-12-21 |
| Temporal Profile of Serum Vitamin D Levels in Foot and Ankle Fusion Surgery (NCT04772196) | Prisma Health-Midlands | 2020-12-21 |
| Efficacy and Safety of Standard of Care Plus Durvalumab in Patients With Limited Disease Small Cell Lung Cancer (DOLPHIN) (NCT04602533) | Michael Hopp | 2020-12-21 |
| Biomarkers in the Brain Oxygen Optimization in Severe Traumatic Brain Injury Trial (NCT04565119) | University of Pennsylvania | 2020-12-20 |
| A Study of TAR-200 in Combination With Cetrelimab, TAR-200 Alone, or Cetrelimab Alone in Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Intravesical Bacillus Calmette-Guérin Who Are Ineligible for or Elected Not to Undergo Radical Cystectomy (NCT04640623) | Janssen Research & Development, LLC | 2020-12-18 |
| Monitoring Local Tissue Oxygen Changes Using the Wireless Lumee Oxygen Platform in Correlation to TcPO2 (NCT04514861) | Profusa, Inc. | 2020-12-18 |
| Niraparib + Dostarlimab In BRCA Mutated Breast Cancer (NCT04584255) | Dana-Farber Cancer Institute | 2020-12-18 |
| Nodify XL2 Classifier Clinical Utility Study in Low to Moderate Risk Lung Nodules (NCT04171492) | Biodesix, Inc. | 2020-12-18 |
| Study to Evaluate the Efficacy, Safety and Tolerability of MAS825 in Patients With Monogenic IL-18 Driven Autoinflammatory Diseases, Including NLRC4-GOF, XIAP Deficiency, or CDC42 Mutations (NCT04641442) | Novartis Pharmaceuticals | 2020-12-18 |
| A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC) (NCT04663308) | Mirum Pharmaceuticals, Inc. | 2020-12-18 |
| A Study of Pembrolizumab and Olaparib for People With Metastatic Pancreatic Ductal Adenocarcinoma and Homologous Recombination Deficiency or Exceptional Treatment Response to Platinum-Based Therapy (NCT04666740) | Memorial Sloan Kettering Cancer Center | 2020-12-18 |
| Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis (NCT04384692) | Fred Hutchinson Cancer Center | 2020-12-18 |
| Observational Prospective Study of Quality of Life in Unresectable TNM Stage III NSCLC (OBSTINATE) (NCT05049044) | Groupe Francais De Pneumo-Cancerologie | 2020-12-18 |
| Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B/KEYMAKER-U03) (NCT04626518) | Merck Sharp & Dohme LLC | 2020-12-17 |
| Testosterone in Bariatric Patients (NCT03721497) | Esbjerg Hospital - University Hospital of Southern Denmark | 2020-12-17 |
| A Phase 1b Study of T-DXd Combinations in HER2-low Advanced or Metastatic Breast Cancer (NCT04556773) | AstraZeneca | 2020-12-17 |
| Effect of Time-restricted Eating on Catecholamine-sensitivity of Adipose Tissue in Obese Adults (NCT04916730) | University of California, San Diego | 2020-12-17 |
| Magenta Elevate™ First-in-Human Clinical Study in High-Risk PCI Patients (NCT06099548) | Magenta Medical Ltd. | 2020-12-17 |
| Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic Insufficiency (NCT04098237) | Andrew Hendifar, MD | 2020-12-17 |
| Dupilumab Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis (NCT04430179) | University of South Florida | 2020-12-17 |
| Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A) (NCT04626479) | Merck Sharp & Dohme LLC | 2020-12-16 |
| A Study of Selumetinib in Chinese Paediatric and Adult Subjects With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN) (NCT04590235) | AstraZeneca | 2020-12-16 |
| Beating Heart Mitral Valve Repair With the HARPOON™ System (NCT04375332) | Edwards Lifesciences | 2020-12-16 |
| ACURATE neo2™ Post Market Clinical Follow up Study (NCT04655248) | Boston Scientific Corporation | 2020-12-16 |
| WATER III: Aquablation vs. Transurethral Laser Enucleation of Large Prostates (80 - 180mL) in Benign Prostatic Hyperplasia (NCT04801381) | University of Bonn | 2020-12-16 |
| Targeted Plasticity Therapy for Posttraumatic Stress Disorder (NCT04064762) | Baylor Research Institute | 2020-12-16 |
| Pre-op Pembro + Radiation Therapy in Breast Cancer (P-RAD) (NCT04443348) | Laura M. Spring, MD | 2020-12-16 |
| Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia (NCT04490915) | Neurocrine Biosciences | 2020-12-16 |
| A Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung Cancer (NCT04351555) | AstraZeneca | 2020-12-16 |
| The Elixir Bioadaptor vs. The Onyx Stent in De Novo Native Coronary Arteries (NCT04192747) | Elixir Medical Corporation | 2020-12-16 |
| Onset PrevenTIon of Urinary Retention in Orthopaedic Nursing and Rehabilitation (NCT04700969) | Örebro University, Sweden | 2020-12-15 |
| A Study of Effectiveness and Safety of the First-Line Nivolumab Plus Ipilimumab With or Without Chemotherapy for Advanced/Recurrent Non-Small Cell Lung Cancer in Japan (NCT05161325) | Bristol-Myers Squibb | 2020-12-15 |
| A Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors (NCT04670679) | Erasca, Inc. | 2020-12-15 |
| A Study of the Combination of Talquetamab and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma (NCT04586426) | Janssen Research & Development, LLC | 2020-12-15 |
| PAnitumumab REchallenge Followed by REgorafenib Versus the Reverse Sequence (NCT04787341) | Gruppo Oncologico del Nord-Ovest | 2020-12-15 |
| To Assess the Safety and Tolerability of Tafasitamab Alone or in Combination With Other Drugs in Japanese Participants With Non-Hodgkins Lymphoma (NHL) (NCT04661007) | Incyte Biosciences Japan GK | 2020-12-15 |
| Acalabrutinib, Umbralisib, and Ublituximab (AU2) In Relapsed and Untreated CLL (NCT04624633) | Jennifer R. Brown, MD, PhD | 2020-12-15 |
| Durvalumab and Tremelimumab in Combination With Y-90 SIRT for Intermediate Stage HCC (NCT04522544) | Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest | 2020-12-15 |
| Long-term Study of ADVM-022 in Neovascular (Wet) AMD [OPTIC-EXT] (NCT04645212) | Adverum Biotechnologies, Inc. | 2020-12-14 |
| Study to Evaluate Rilzabrutinib in Adults and Adolescents With Persistent or Chronic Immune Thrombocytopenia (ITP) (NCT04562766) | Principia Biopharma, a Sanofi Company | 2020-12-14 |
| Thermal Ablation of Cervical Metastases From Thyroid Carcinoma (NCT04522570) | Instituto do Cancer do Estado de São Paulo | 2020-12-14 |
| Eating Behaviors in Shift Workers (NCT04468672) | Columbia University | 2020-12-14 |
| An Educational Program to Improve Cardiac Arrest Diagnostic Accuracy of Ambulance Telecommunicators (NCT03894059) | Ottawa Hospital Research Institute | 2020-12-14 |
| Clinical Trial for Near Infrared Endoventricular Illumination for Neuroprotection in Very Early Cases of Parkinson's Disease (Ev-NIRT) (NCT04261569) | University Hospital, Grenoble | 2020-12-14 |
| GYNecological Cancers Treated with NETrin MAbs in Combination with Chemotherapy and /or Pembrolizumab (NCT04652076) | NETRIS Pharma | 2020-12-14 |
| A Study in Participants With Advanced Cancers Associated With Expression of DLL3 (MK-6070-001/HPN328-4001) (NCT04471727) | Harpoon Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2020-12-14 |
| Effects of Increased Maternal Choline Intake on Child Cognitive Development (NCT04987099) | Cornell University | 2020-12-13 |