| Hypofractionated Radiation Therapy and Bintrafusp Alfa for the Treatment of Advanced Intrahepatic Cholangiocarcinoma (NCT04708067) | M.D. Anderson Cancer Center | 2021-08-31 |
| A Study to Evaluate the Safety, Tolerability, and Exploratory Efficacy of IMS001 in Subjects With Multiple Sclerosis (NCT04956744) | ImStem Biotechnology | 2021-08-31 |
| Sleep Disturbance and Emotion Regulation Brain Dysfunction as Mechanisms of Neuropsychiatric Symptoms in Alzheimer's Dementia (NCT04100057) | Stanford University | 2021-08-31 |
| Autonomic Determinants of POTS - Pilot 2 (NCT04140721) | Vanderbilt University Medical Center | 2021-08-31 |
| Study to Evaluate the Efficacy, Immunogenicity, and Safety of RSVpreF in Adults. (NCT05035212) | Pfizer | 2021-08-31 |
| Does Screening With the Galleri Test in the NHS Reduce the Likelihood of a Late-stage Cancer Diagnosis in an Asymptomatic Population? A Randomised Clinical Trial (NCT05611632) | GRAIL, Inc. | 2021-08-31 |
| Emodepside Phase II Trial for Treatment of Onchocerciasis (NCT05180461) | Drugs for Neglected Diseases | 2021-08-30 |
| Feasibility of [11C]Acetate-PET in LAM and TSC (NCT05467397) | Brigham and Women's Hospital | 2021-08-30 |
| RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation (NCT05036018) | Leipzig Heart Science gGmbH | 2021-08-30 |
| STretch and Myocardial Characterization in Arrythmogenic Mitral Valve Prolapse-2 (NCT04852731) | Central Hospital, Nancy, France | 2021-08-30 |
| Iyengar Yoga for Prolonged Grief Disorder (NCT05026827) | Medical College of Wisconsin | 2021-08-30 |
| Study in Parkinson Disease of Exercise (NCT04284436) | Northwestern University | 2021-08-30 |
| A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction (NCT03776162) | The Cleveland Clinic | 2021-08-30 |
| PRL3-Zumab in Patients With Advanced Solid Tumors (NCT07541001) | Intra-IMMUSG Pte Ltd | 2021-08-30 |
| A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease (NCT04929210) | Janssen Research & Development, LLC | 2021-08-30 |
| Pre-Exposure Prophylaxis Study of Lenacapavir and Emtricitabine/Tenofovir Alafenamide in Adolescent Girls and Young Women at Risk of HIV Infection (NCT04994509) | Gilead Sciences | 2021-08-30 |
| Recovery Management Checkups for Opioid Use Disorder Experiment (NCT04365920) | Chestnut Health Systems | 2021-08-29 |
| Oncogenetic Panel and Integrated Clinical Data Registry Study for Wild Type Gastrointestinal Stromal Tumor Patients (NCT04821895) | National Health Research Institutes, Taiwan | 2021-08-28 |
| Pilot Study to Enable Electronic Laboratory Data Transfer From Participating Institutions to MediData/RAVE (NCT05020951) | Children's Oncology Group | 2021-08-28 |
| The Hancock Jaffe Surgical Antireflux Venous Valve Endoprosthesis Study (NCT04943172) | Hancock Jaffe Laboratiores, Inc | 2021-08-27 |
| Progressive Abduction Loading Therapy (NCT04118998) | Northwestern University | 2021-08-27 |
| Neoadjuvant Dietary Intervention in Intermediate Risk Prostate Cancer (NCT04985565) | M.D. Anderson Cancer Center | 2021-08-27 |
| Sex-specific Determinants of Early-phase Recovery From Skeletal Muscle Disuse (NCT04151901) | The University of Texas Health Science Center at San Antonio | 2021-08-27 |
| A Study of AK104 Plus Platinum-containing Chemotherapy±Bevacizumab as First-line Treatment for Persistent, Recurrent, or Metastatic Cervical Cancer (NCT04982237) | Akeso | 2021-08-27 |
| A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer) (NCT04961996) | Hoffmann-La Roche | 2021-08-27 |
| Study of Cardiopulmonary Exercise Testing in Women Who Have HER2-Positive Breast Cancer With Mild Cardiotoxicity (NCT05036252) | Memorial Sloan Kettering Cancer Center | 2021-08-27 |
| A Donanemab (LY3002813) Study in Participants With Preclinical Alzheimer's Disease (TRAILBLAZER-ALZ 3) (NCT05026866) | Eli Lilly and Company | 2021-08-27 |
| Non-invasive Brain Stimulation Normalizes Dopaminergic Transmission in the Frontostriatal Circuit to Alleviate Depression With Metabolic Disorders. (NCT05117983) | National Cheng-Kung University Hospital | 2021-08-26 |
| Assessing Pharmacokinetics and Pharmacodynamics of Daily Enteric-coated Aspirin in Patients With StablE Diabetes (NCT05105919) | Montreal Heart Institute | 2021-08-26 |
| Potassium Canrenoate in Brain-dead Organ Donors: Randomized Controlled Clinical Trial (NCT04714710) | Pr. Nicolas GIRERD | 2021-08-26 |
| Comparison of the Pathological Effect Between 2 and 4 Cycles Neoadjuvant CAPOX for Low/Intermediate Risk II/III Rectal Cancer (NCT04922853) | West China Hospital | 2021-08-26 |
| A Study of Guselkumab and Interleukin-17 (IL-17) Inhibitor Therapies in Participants With Psoriatic Arthritis in Routine Clinical Practice (NCT05049798) | Janssen Pharmaceutica N.V., Belgium | 2021-08-25 |
| Testing the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial Cancer (NCT04491942) | National Cancer Institute (NCI) | 2021-08-25 |
| Tazemetostat in Malignant Peripheral Nerve Sheath Tumors (NCT04917042) | University of Florida | 2021-08-25 |
| MElanoma Research Lymph Node Prediction Implementation National_001 (NCT04759781) | SkylineDx | 2021-08-25 |
| A Longitudinal Study on Longstanding Complicated Fatigue (NCT04955587) | Stockholm University | 2021-08-24 |
| Dose-finding Study: Popliteal Sciatic Nerve Block in Patients Undergoing Diabetic Foot Surgery (NCT04981067) | Seoul National University Hospital | 2021-08-24 |
| Anlotinib Combined With Carboplatin/Paclitaxel as First-line Treatment in Patients With Advanced Ovarian Cancer (NCT04807166) | Wenjun Cheng | 2021-08-24 |
| The Value of a Risk Prediction Tool (PERSARC) for Effective Treatment Decisions of Soft-tissue Sarcomas Patients (NCT05741944) | Leiden University Medical Center | 2021-08-24 |
| Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma (NCT04331041) | Washington University School of Medicine | 2021-08-24 |
| Association Between Gut Microbiome and Dietary Determinants and Vaccine Response (NCT05239403) | M.D. Anderson Cancer Center | 2021-08-24 |
| Phase-2 Dacomitinib Study on Patients With EGFR-Driven Advanced Solid Tumours With Low EGFR-AS1 IncRNA Expr or Other Novel Emerging Biomarkers (NCT04946968) | National Cancer Centre, Singapore | 2021-08-24 |
| Use of an Interactive 3D Tool During Consultation for Breast Reconstruction Surgery (NCT05025020) | Memorial Sloan Kettering Cancer Center | 2021-08-23 |
| Follow-up After Surgery for Colorectal Cancer (NCT05656326) | Erasmus Medical Center | 2021-08-23 |
| Acalabrutinib in CNSL (NCT04906902) | Dana-Farber Cancer Institute | 2021-08-23 |
| Effectiveness of Antiviral Treatment in Cirrhotic Patients with Low-level Hepatitis B Virus DNA Levels (NCT04780204) | Asan Medical Center | 2021-08-23 |
| Bone-sparing Chemoradiotherapy for Anal Cancer - DACG-II (NCT05385250) | Karen-Lise Garm Spindler | 2021-08-23 |
| REFLECTION: A Clinical Practice Learning Program for Galleri® (NCT05205967) | GRAIL, Inc. | 2021-08-23 |
| HAI-Floxuridine, or Liver-Tx, Combined With 2nd Line Chemotherapy Versus 2nd Line Chemotherapy Alone for Patients With Colorectal Liver Metastases and Heavy Tumour Burden. (NCT04898504) | Oslo University Hospital | 2021-08-23 |
| App-Based Mindfulness Intervention for the Improvement of Quality of Life in Patients With Metastatic Renal Cell Cancer (NCT04788095) | City of Hope Medical Center | 2021-08-23 |
| A Multicenter Randomized Open-label Study of Diammonium Glycyrrhizinate Enteric-coated Capsule Plus DXM Versus DXM in Treatment of ITP (NCT05023915) | Shandong University | 2021-08-21 |
| Predictive Multimodal Signatures Associated With Response to Treatment and Prognosis of Patients With Stage IV Non-small Cell Lung Cancer (NCT04994795) | Sophia Genetics SAS | 2021-08-21 |
| NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers (NCT05020678) | Nkarta, Inc. | 2021-08-20 |
| Hypotension Prediction Index: Correlations Between Invasive and Non-invasive Pressure Points. (NCT05025176) | University of California, Davis | 2021-08-20 |
| Antirotinib Hydrochloride Plus Whole Brain Radiotherapy for Small Cell Lung Cancer With Brain Metastases (NCT06611657) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2021-08-20 |
| CSRS Implementation - A Pilot Study (NCT04790058) | Ottawa Hospital Research Institute | 2021-08-20 |
| Urinary Exosomal Biomarkers of Thyroglobulin and Galectin-3 for Prognosis and Follow-up in Patients of Thyroid Cancer (NCT04948437) | National Taiwan University Hospital | 2021-08-19 |
| A Trial of a Multimodal Lifestyle Intervention to Optimize Survivorship After Cancer (NCT04987359) | Pennington Biomedical Research Center | 2021-08-19 |
| Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98) (NCT04938817) | Merck Sharp & Dohme LLC | 2021-08-19 |
| STOP Persistent AF PAS (NCT05005949) | Medtronic Cardiac Ablation Solutions | 2021-08-19 |
| Testing the Addition of the Anti-cancer Drug, Tazemetostat, to the Usual Treatment (Dabrafenib and Trametinib) for Metastatic Melanoma That Has Progressed on the Usual Treatment (NCT04557956) | National Cancer Institute (NCI) | 2021-08-19 |
| Assessing an EEG Biomarker of Response to TMS for Major Depression (NCT05008198) | VA Office of Research and Development | 2021-08-19 |
| A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 ) (NCT04849728) | Inventiva Pharma | 2021-08-19 |
| A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy (NCT04923893) | Janssen Research & Development, LLC | 2021-08-19 |
| Evaluate the Safety and Effectiveness of iSTAR Medical's MINIject™ Implant for Lowering Intraocular Pressure (IOP) in Subjects With Primary Open-angle Glaucoma. (NCT05024695) | iSTAR Medical | 2021-08-19 |
| GFRα4 CAR T Cells in MTC Patients (NCT04877613) | University of Pennsylvania | 2021-08-19 |
| Efficacy and Safety of Carfilzomib in Combination With Ibrutinib vs Ibrutinib in Waldenström's Macroglobulinemia (NCT04263480) | Christian Buske | 2021-08-18 |
| Selinexor With Alternating Bortezomib or Lenalidomide Plus Dexamethasone in TIE Newly Diagnosed MM Patients (NCT04717700) | Ida Bruun Kristensen | 2021-08-18 |
| Transportation Safety in Adolescence (NCT03639753) | University of Pennsylvania | 2021-08-18 |
| Pembrolizumab Plus Lenvatinib in Combination With Belzutifan in Solid Tumors (MK-6482-016) (NCT04976634) | Merck Sharp & Dohme LLC | 2021-08-18 |
| Effect of Daily Erythritol Versus Sucrose Intake Over 5 Weeks on Glucose Tolerance in Adolescents (NCT04966299) | University Hospital, Basel, Switzerland | 2021-08-18 |
| Frontline Treatment of Follicular Lymphoma With AtezolizUmab and Obinutuzumab With and Without RadiOtherapy (NCT04962126) | Olivia Newton-John Cancer Research Institute | 2021-08-17 |
| Multi-centre Study to Evaluate ACAF Versus Laminoplasty in Treating Cervical Ossification of the Posterior Longitudinal Ligament (NCT04968028) | Shanghai Changzheng Hospital | 2021-08-17 |
| Chronic Pain Management In Primary Care Using Behavioral Health Consultants (NCT04680000) | The University of Texas Health Science Center at San Antonio | 2021-08-17 |
| The Cryopreserved vs. Liquid Platelets Trial (NCT03991481) | Australian and New Zealand Intensive Care Research Centre | 2021-08-17 |
| A Study of Penpulimab (AK105) in the First-line Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma (NCT04974398) | Akeso | 2021-08-16 |
| Prevention With the Health and Lifestyle Tool (NCT05006508) | Region Skane | 2021-08-16 |
| High-intensity Interval Exercise in Rheumatoid Arthritis (NCT05768165) | Vastra Gotaland Region | 2021-08-16 |
| Long-Term Follow-up of Subjects Who Were Treated With ST-920 (NCT05039866) | Sangamo Therapeutics | 2021-08-16 |
| A Study to Evaluate White Matter Hyperintensities in Migraine (NCT05112289) | Mayo Clinic | 2021-08-16 |
| A Study of Tazemetostat on Safety in Participants With Relapsed or Refractory Follicular Lymphoma With Enhancer of Zeste Homolog 2 (EZH2) Gene Mutation in Japan (NCT05228158) | Eisai Co., Ltd. | 2021-08-16 |
| Pilot Sensor Randomized Controlled Trial: Setting Expectations to Increase Satisfactory Outcomes After Total Knee Replacement (NCT04775719) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2021-08-16 |
| MR Guided Focused Ultrasound (FUS) for the Treatment of Trigeminal Neuralgia (NCT04579692) | University of Maryland, Baltimore | 2021-08-16 |
| Effect of a Postural Re-education Intervention Compared to Standard Care on Scoliosis Progression in Adolescent (NCT04568759) | St. Justine's Hospital | 2021-08-15 |
| mFOLFIRINOX With or Without Stereotactic Body Radiotherapy in Locally Advanced Pancreatic Adenocarcinoma (NCT04986930) | Asan Medical Center | 2021-08-14 |
| Testing the Addition of an Anticancer Drug, BAY 1895344, to the Usual Chemotherapy With FOLFIRI in Advanced or Metastatic Cancers of the Stomach and Intestines (NCT04535401) | National Cancer Institute (NCI) | 2021-08-13 |
| RVU120 (SEL120) in Patients with Relapse/Refractory Metastatic or Advanced Solid Tumors (NCT05052255) | Ryvu Therapeutics SA | 2021-08-13 |
| Phase II Study of Neoadjuvant ArOMatase Inhibitor Therapy for ER+ Breast Cancer (NAOMI) (NCT04568616) | Dartmouth-Hitchcock Medical Center | 2021-08-13 |
| A Trial of AK117 (Anti-CD47 Antibody) in Patients With Acute Myeloid Leukemia (NCT04980885) | Akeso | 2021-08-13 |
| Brain Boosters 2 in Persons at Risk for Alzheimer's Disease: a Digital Application Supported Intervention (NCT05027789) | University of California, Davis | 2021-08-13 |
| Taking AIM at Breast Cancer (NCT04720209) | Dana-Farber Cancer Institute | 2021-08-13 |
| Study of ADXS-504 Immunotherapy for Recurrent Prostate Cancer (NCT05077098) | Mark Stein | 2021-08-12 |
| Impact of Adolescent Vaccine Reminder Notices Sent Via Preferred Method of Communication on HPV Vaccination (NCT05148559) | Huong Nguyen, PhD | 2021-08-12 |
| Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis (NCT04624230) | Pfizer | 2021-08-12 |
| Single Fraction Accelerated Partial Breast Irradiation vs. Five Fraction Accelerated Partial Breast Irradiation for Low-risk Stage 0 and I Breast Carcinoma (NCT04849871) | Washington University School of Medicine | 2021-08-12 |
| REvascularization and Valve Intervention for Ischemic Valve diseasE: REVIVE Trial (NCT04822675) | Ottawa Heart Institute Research Corporation | 2021-08-12 |
| Effectivity and Safety of PFO Closure vs Medicine in Alleviating Migraine (NCT04946734) | Guangdong Provincial People's Hospital | 2021-08-12 |
| Befotertinib and Icotinib in Treatment-naive Patients With Advanced EGFR-Mutant Lung Cancer (NCT05007938) | Betta Pharmaceuticals Co., Ltd. | 2021-08-12 |
| Methotrexate in Erosive Inflammatory Hand Osteoarthritis (NCT04579848) | Diakonhjemmet Hospital | 2021-08-12 |
| Study Assessing Long-teRm Outcomes of dupiluMAb (DUPIXENT®) Treatment in Adult Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP) (NCT04959448) | Regeneron Pharmaceuticals | 2021-08-12 |