| Neoadjuvant Sasanlimab With Radiation as an in Situ Vaccine for Cisplatin-ineligible Muscle Invasive Bladder Cancer (NCT05241340) | The Methodist Hospital Research Institute | 2022-02-15 |
| Effect of Physical Activity and Pain Education on Endometriosis-associated Pain (NCT05091268) | University Hospital, Akershus | 2022-02-15 |
| Phase II Trial of Pembrolizumab in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer (NCT05119296) | Stanford University | 2022-02-15 |
| Anakinra for Preterm Infants Pilot (NCT05280340) | Monash Medical Centre | 2022-02-15 |
| Radiomics of Treatment-naive Prostate Cancer Patients on Multiparametric MRI for Risk Stratification and Treatment Outcomes Predictions (NCT06126172) | Chang Gung Memorial Hospital | 2022-02-15 |
| Neuropsychiatric Post-Acute Sequelae of SARS-CoV-2 (PASC) Using TSPO Positron Emission Tomography (PET) and MRI (NCT05615415) | NYU Langone Health | 2022-02-15 |
| Unraveling the Role of Extracellular Vesicles-driven Senescence in Myeloproliferative Neoplasms (NCT06798805) | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 2022-02-15 |
| A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Urological Tumors and Other Solid Tumors (NCT05393427) | Sichuan Baili Pharmaceutical Co., Ltd. | 2022-02-15 |
| Phase 3 Study of Anifrolumab in Adult Patients With Active Proliferative Lupus Nephritis (NCT05138133) | AstraZeneca | 2022-02-15 |
| Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty (NCT05300685) | University of California, San Francisco | 2022-02-15 |
| Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma (NCT05041153) | M.D. Anderson Cancer Center | 2022-02-14 |
| Sickle Cell Disease Obstetric Multi-Disciplinary Care Programme (NCT05143021) | Vanderbilt University Medical Center | 2022-02-14 |
| Critical Windows in the Development of Asthma Endotypes and Phenotypes in High-Risk Toddlers (NCT05210361) | University of Colorado, Denver | 2022-02-14 |
| A Long-Term Safety Study of PTC923 in Participants With Phenylketonuria (NCT05166161) | PTC Therapeutics | 2022-02-14 |
| Long-term Follow-up Study of Allogeneic Gamma Delta (γδ) CAR T Cells (NCT04911478) | Adicet Therapeutics | 2022-02-14 |
| A Phase III Study of JR-141 in Patients With Mucopolysaccharidosis II (STARLIGHT) (NCT04573023) | JCR Pharmaceuticals Co., Ltd. | 2022-02-14 |
| 177Lu-PSMA-I&T for Metastatic Castration-Resistant Prostate Cancer (NCT05204927) | Curium US LLC | 2022-02-14 |
| A Study of a Patient-Specific Neoantigen Vaccine in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer (NCT05141721) | Seattle Project Corporation | 2022-02-12 |
| A Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult Participants (NCT05217641) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-02-11 |
| Creating a Healthy L.I.F.E: Lifestyle Interventions For Epilepsy (NCT05283200) | Imad Najm MD | 2022-02-11 |
| Pembrolizumab and Radiotherapy for Patients With NK/T Cell Lymphoma (NCT04417166) | International Extranodal Lymphoma Study Group (IELSG) | 2022-02-11 |
| A Study Evaluating the Efficacy and Safety of Mitapivat (AG-348) in Participants With Sickle Cell Disease (RISE UP) (NCT05031780) | Agios Pharmaceuticals, Inc. | 2022-02-11 |
| Acceptability Research on Integrated Point of Care Sexually Transmitted Infection (STI) Testing and Expedited Partner Therapy (EPT) (NCT06570733) | Wits RHI Research Centre Clinical Research Site | 2022-02-11 |
| Atorvastatin Effect on Reduction of COPD Exacerbations (NCT04789057) | Medical University of Bialystok | 2022-02-11 |
| Liver Cancer Prevention Randomized Control Trial (NCT05196867) | M.D. Anderson Cancer Center | 2022-02-11 |
| Trial to Assess the Safety and Efficacy of Sirolimus-Coated Balloon vs. Uncoated Standard Angioplasty for the Treatment of Below-the-knee Peripheral Arterial Disease (NCT04772300) | Jena University Hospital | 2022-02-10 |
| LIFE-BTK PK Sub-study (NCT05208905) | Abbott Medical Devices | 2022-02-10 |
| Testing Oral Decitabine and Cedazuridine (ASTX727) in Combination With Venetoclax for Higher-Risk Acute Myeloid Leukemia Patients (NCT04817241) | National Cancer Institute (NCI) | 2022-02-10 |
| BIOlogics in Severe Nasal POlyposis SurvEy (NCT05228041) | University Hospital, Lille | 2022-02-10 |
| Efficacy of Diet on Quality of Life in Multiple Sclerosis (NCT05007483) | Terry L. Wahls | 2022-02-10 |
| Application of Time Restriction Feeding in Patients With Type 2 Diabetes Mellitus (NCT05015504) | OhioHealth | 2022-02-10 |
| All Japanese Population: Belantamab Mafodotin Plus Pomalidomide and Dexamethasone (Pd) Versus Bortezomib Plus Pd in Relapsed/Refractory Multiple Myeloma (NCT06956170) | GlaxoSmithKline | 2022-02-10 |
| Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes (NCT04542148) | University of Alabama at Birmingham | 2022-02-10 |
| Wearable Electrical Stimulation on the Back to Modulate Spinal Cord Activity (NCT05669508) | Thomas Jefferson University | 2022-02-10 |
| PD1 Combined With Chemotherapy for Adjuvant Treatment of Gastric Cancer (NCT05180734) | Shanghai Junshi Bioscience Co., Ltd. | 2022-02-10 |
| Effect of Tao Calligraphy Meditation and Energized Water on Depression (NCT06934330) | Sha Research Foundation | 2022-02-10 |
| Retrospective Study to Evaluate the Effectiveness of the Approach to Enuresis in Our Center (NCT06764498) | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 2022-02-10 |
| Long-term Assessment of the Safety and Performance of the NuVasive Simplify Disc (NCT05258435) | NuVasive | 2022-02-09 |
| Social Support and Reduced Fear Acquisition (NCT04564976) | University of California, Los Angeles | 2022-02-09 |
| TReatment for ImmUne Mediated PathopHysiology (NCT04862221) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2022-02-09 |
| A Study of GNC-035, a Tetra-specific Antibody, in Participants With Relapsed/Refractory Hematologic Malignancy (NCT05104775) | Sichuan Baili Pharmaceutical Co., Ltd. | 2022-02-09 |
| To Evaluate the Safety and Efficacy of Human Derived Anti-BCMA CAR-T Injection for Subjects with R/R MM (NCT05302648) | Hrain Biotechnology Co., Ltd. | 2022-02-09 |
| A Patient-Partnered, Pan-Canadian, Comparative Effectiveness Evaluation of an Acute Pediatric Mental Health and Addiction Care Bundle (NCT04902391) | University of Calgary | 2022-02-09 |
| Testing the Response to the Anti-cancer Drug, Triapine, in Uterine Cancers Using Markers From the Tissue at the Time of Hysterectomy (NCT04494113) | National Cancer Institute (NCI) | 2022-02-08 |
| Combination With Sintilimab and XELOX+Bevacizumab as 1st Line Therapy in RAS-mutant Metastatic Colorectal Cancer (NCT05171660) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2022-02-08 |
| Modifying Immunity in Children With DihydROartemisinin-Piperaquine (MIC-DroP) (NCT04978272) | Grant Dorsey, M.D, Ph.D. | 2022-02-08 |
| Improving Pain Management Via Spinal Cord Stimulation and Blood Pressure Reduction (NCT04676399) | University of Kansas Medical Center | 2022-02-08 |
| Impact of 18F-FES PET on the Therapeutic Treatment of Patients With Metastatic Breast Cancer (NCT05486182) | GE Healthcare | 2022-02-08 |
| Role of Statins In Slowing Rheumatic Heart Disease (RHD) Progression (NCT04575857) | University of Washington | 2022-02-08 |
| Testing Nivolumab and Ipilimumab With Short-Course Radiation in Locally Advanced Rectal Cancer (NCT04751370) | National Cancer Institute (NCI) | 2022-02-08 |
| Predictive Model for 1-Year Pain and Function Outcomes After Thumb Joint Surgery in Osteoarthritic Patients (NCT06740851) | Michael Oyewale | 2022-02-08 |
| Hotspot TCR-T: A Phase I/Ib Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T) (NCT04520711) | Providence Health & Services | 2022-02-08 |
| Subthreshold SCS or BMT (NCT05169047) | Moens Maarten | 2022-02-07 |
| Myo-Inositol for Infertility in PCOS (NCT04407754) | University of Oklahoma | 2022-02-07 |
| A Clinical Trial of AAV2-BDNF Gene Therapy in Early Alzheimer's Disease and Mild Cognitive Impairment (NCT05040217) | Mark Tuszynski | 2022-02-07 |
| Kebele Elimination of Trachoma for Ocular Health (NCT03335072) | University of California, San Francisco | 2022-02-07 |
| Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease (NCT05202509) | NewAmsterdam Pharma | 2022-02-07 |
| A Global Study to Assess the Effects of Durvalumab With Oleclumab or Durvalumab With Monalizumab Following Concurrent Chemoradiation in Patients With Stage III Unresectable Non-Small Cell Lung Cancer (NCT05221840) | AstraZeneca | 2022-02-07 |
| Clinical and Molecular Correlates of Response to First Line Treatment in Lichen Planus (NCT05330572) | University of Aberdeen | 2022-02-07 |
| Neoadjuvant Lazertinib With or Without Chemotherapy for Patients With EGFR-mutated Resectable Non-small Cell Lung Cancer (NCT06268210) | Yonsei University | 2022-02-07 |
| PD-1 Antibody Therapy + Infliximab for Metastatic Melanoma (NCT05034536) | Massachusetts General Hospital | 2022-02-07 |
| Personalizing Perioperative Analgesia in Children (NCT01140724) | Senthil Sadhasivam | 2022-02-07 |
| Treatment of Anxiety Disorders With Trigeminal Nerve Stimulation (NCT04931134) | Dr. Rafael Freire | 2022-02-07 |
| Insignia™ Hip Stem Outcomes Study (NCT05144191) | Stryker Orthopaedics | 2022-02-07 |
| Effects of and Exploring the Processes of Free Movement Dance as a Physical Therapy Intervention for Female Patients Diagnosed With Chronic Widespread Pain (Including Fibromyalgia). (NCT05282758) | Göteborg University | 2022-02-07 |
| Breathwork-assisted Treatment for Cannabis Use Disorder (NCT05219825) | Elias Dakwar | 2022-02-06 |
| Lurbinectedin + Doxorubicin In Leiomyosarcoma (NCT05099666) | Massachusetts General Hospital | 2022-02-04 |
| Study of Pembrolizumab (MK-3475) Versus Chemotherapy in Mismatch Repair Deficient (dMMR) Advanced or Recurrent Endometrial Carcinoma (MK-3475-C93/KEYNOTE-C93/GOG-3064/ENGOT-en15) (NCT05173987) | Merck Sharp & Dohme LLC | 2022-02-03 |
| Post-Marketing Surveillance (Special Use-results Surveillance on Long-term Use) With Sogroya® (NCT05230550) | Novo Nordisk A/S | 2022-02-03 |
| Postmortem Evaluation of Adrenal and Other Endocrine Tumors in Patients With Sudden Death (NCT05446779) | Helsinki University Central Hospital | 2022-02-03 |
| MR Antagonist and LSD1 (NCT04840342) | Brigham and Women's Hospital | 2022-02-03 |
| A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOGAD) (NCT05063162) | UCB Biopharma SRL | 2022-02-02 |
| Study of Pembrolizumab Combined With Decitabine and Pralatrexate in PTCL and CTCL (NCT03240211) | University of Virginia | 2022-02-02 |
| Impact of an Alternative to Incarceration by Housing and Support by Assertive Community Treatment Team for Homeless People With Severe Psychiatric Disorders Referred to Referral Procedures : AILSI Program (NCT06025006) | Assistance Publique Hopitaux De Marseille | 2022-02-02 |
| Safety and Immunogenicity of CRV-101 Vaccine for the Prevention of Herpes Zoster in Adults Aged 50 Years and Older (NCT05304351) | Curevo Inc | 2022-02-02 |
| Assessment of Depression Levels in Elderly Patients With an Orthopedic Fracture Compared to Patients After a Stroke. (NCT06570356) | Shmuel Harofeh Hospital, Geriatric Medical Center | 2022-02-02 |
| First in Human Study of TORL-2-307-ADC in Participants With Advanced Cancer (NCT05156866) | TORL Biotherapeutics, LLC | 2022-02-02 |
| Neoadjuvant and Adjuvant Lenvatinib in HCC Patients Treated by Percutaneous Ablative (NCT05113186) | Assistance Publique - Hôpitaux de Paris | 2022-02-02 |
| Energy Metabolism and Acute Effects of Protein Diets in Metabolically Obese Normal Weight Individuals (NCT06802341) | Singapore Institute of Food and Biotechnology Innovation | 2022-02-01 |
| Coronavirus Disease 2019 (Covid-19) Impact on Alcohol-related Liver Disease Patient Outcomes, Care and Alcohol Use (NCT05191446) | University of California, San Francisco | 2022-02-01 |
| Homeless Veterans and Peer Whole Health Coaching (NCT05176977) | VA Office of Research and Development | 2022-02-01 |
| Primary Care Implementation and Evaluation of Coach McLungs (NCT05059210) | Wake Forest University Health Sciences | 2022-02-01 |
| Family Functioning and Adverse Side Effects of Family-based Therapy for Anorexia Nervosa (NCT06097247) | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | 2022-02-01 |
| Effectiveness of Treatments for Cirrhosis With Varicose Veins (NCT06961474) | Shanghai Zhongshan Hospital | 2022-02-01 |
| Social Support and Enhanced Fear Extinction (NCT04565041) | University of California, Los Angeles | 2022-02-01 |
| A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab Monotherapy in Participants With Select B-Cell Malignancies (NCT05207670) | Genentech, Inc. | 2022-02-01 |
| Mitoxantrone Hydrochloride Liposome Injection-containing Bridging Regimen and CD19-targeting CAR-T Therapies (NCT06220097) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2022-02-01 |
| Medical-legal Partnerships to Prevent Evictions and Homelessness Among Veterans (NCT04924088) | VA Office of Research and Development | 2022-02-01 |
| Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System (NCT04770870) | DT MedTech, LLC | 2022-02-01 |
| Consulting After Combat: Interviewing Veterans to Develop a Therapy to Restore Functioning and Reintegration After Moral Injury Events (NCT05020587) | VA Office of Research and Development | 2022-02-01 |
| DASH Diet in Heart Failure Outpatients (NCT05117086) | University of California, Davis | 2022-02-01 |
| Sleep Restriction Therapy for Insomnia in Primary Health Care (NCT04975776) | Region Stockholm | 2022-02-01 |
| Perception of Electrical Stimuli in Individuals With Stroke (NCT05465005) | Netta Gurari | 2022-02-01 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN) (NCT05262023) | Denali Therapeutics Inc. | 2022-02-01 |
| Geniculate Artery Embolization for Osteoarthritis (NCT04456569) | University of Minnesota | 2022-02-01 |
| Ultrasound-guided Interscalene Brachial Plexus Block: Single Bolus vs Continuous Catheter Placement in Arthroscopic Rotator Cuff Repair (NCT06855381) | University of Foggia | 2022-02-01 |
| Tracking Atrial Fibrillation After Intensive Care Admission (NCT05229211) | University of Oxford | 2022-02-01 |
| A Study of Anvumetostat in Participants With Advanced MTAP-null Solid Tumors (MTAPESTRY 101) (NCT05094336) | Amgen | 2022-02-01 |
| Efficacy of a Combined ACT+ App Intervention to Improve Psychological Flexibility and Associated Symptoms in Cancer Patients (NCT05126823) | Francisco Garcia Torres | 2022-02-01 |
| Risk Stratification and Heterogeneity for Organ Damage in Acute Diquat Poisoning (NCT06798142) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2022-02-01 |