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Regeneron Pharmaceuticals

398 clinical trials · Sponsor

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RecordFirmDate
A Trial to Learn if Odronextamab Combined With Chemotherapy is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Chemotherapy for Adult Participants With Follicular Lymphoma (NCT06097364)Regeneron Pharmaceuticals2023-11-14
An Observational Extension Study for Adult Patients Treated in Study R5459-RT-1944 Who Receive a Kidney Transplant (NCT05106387)Regeneron Pharmaceuticals2023-10-19
A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma (NCT05730036)Regeneron Pharmaceuticals2023-09-18
A Trial to Learn How the Combination of Fianlimab With Cemiplimab and Chemotherapy Works Compared With Cemiplimab and Chemotherapy for Treating Adult Patients With Advanced Non-small Cell Lung Cancer (NCT05800015)Regeneron Pharmaceuticals2023-08-08
A Trial to Learn if Different Doses of REGN7544 Are Safe in Healthy Adult Participants (NCT05970718)Regeneron Pharmaceuticals2023-08-07
A Study to Learn if a Combination of Fianlimab and Cemiplimab Versus Cemiplimab Alone is More Effective for Adult Participants With Advanced Non-Small Cell Lung Cancer (NSCLC) (NCT05785767)Regeneron Pharmaceuticals2023-06-30
A Non-Interventional Study of Clinical Characteristics and Mortality of US Patients With Fibrodysplasia Ossificans Progressiva (FOP) (NCT06064656)Regeneron Pharmaceuticals2023-06-29
A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations (NCT05788536)Regeneron Pharmaceuticals2023-06-27
A Trial to Learn How Well REGN9933 Works for Preventing Blood Clots After Knee Replacement Surgery in Adult Participants (NCT05618808)Regeneron Pharmaceuticals2023-05-24
A Study to Learn How Well Dupilumab Works in Adult and Adolescent Participants With Eosinophilic Gastritis With or Without Eosinophilic Duodenitis and the Side Effects it May Have (NCT05831176)Regeneron Pharmaceuticals2023-05-03
A Trial to Study if REGN5837 in Combination With Odronextamab is Safe for Adult Participants With Aggressive B-cell Non-Hodgkin Lymphomas (NCT05685173)Regeneron Pharmaceuticals2023-04-20
A Study in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate How Safe Long-term Treatment With Pozelimab + Cemdisiran Combination Therapy is and How Well it Works (NCT05744921)Regeneron Pharmaceuticals2023-03-07
A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition (NCT05519475)Regeneron Pharmaceuticals2023-02-09
A Study of ImmunoPet Imaging Using 89Zr-DFO-REGN5054 in Adult Participants With Solid Cancers Treated With Cemiplimab (NCT05259709)Regeneron Pharmaceuticals2023-02-07
A Trial to See if the Combination of Fianlimab With Cemiplimab Works Better Than Pembrolizumab for Preventing or Delaying Melanoma From Coming Back After it Has Been Removed With Surgery (NCT05608291)Regeneron Pharmaceuticals2023-01-16
A Trial to Learn if Single Ascending Intravenous (IV) Doses of REGN7508 Are Safe and Well Tolerated, and How it Works in the Body of Healthy Adult Participants (NCT05603195)Regeneron Pharmaceuticals2023-01-12
Dupilumab in Adolescent and Adult Skin of Color Participants: Open-label Moderate-to-severe Eczema Trial (NCT05590585)Regeneron Pharmaceuticals2023-01-11
Real-World Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (NCT05673967)Regeneron Pharmaceuticals2023-01-09
Assess Gastrointestinal Blood Loss After Receiving Aspirin or Aspirin Plus Rivaroxaban in Healthy Adult Participants (NCT05546957)Regeneron Pharmaceuticals2023-01-05
A Study to Assess Safety, Tolerability and Efficacy of Garetosmab Versus Placebo Administered Intravenously (IV) in Adult Participants With Fibrodysplasia Ossificans Progressiva (FOP) (NCT05394116)Regeneron Pharmaceuticals2022-11-21
An Observational Study to Assess the Effectiveness and Safety of a Cemiplimab in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) in Routine Clinical Practice Settings in Europe (NCT05363319)Regeneron Pharmaceuticals2022-10-26
A Trial to Learn if REGN7999 is Safe and Well Tolerated, and How it Works in the Body of Healthy Participants (NCT05481333)Regeneron Pharmaceuticals2022-10-24
Efficacy and Safety of the Combination of Pozelimab and Cemdisiran Versus Continued Eculizumab or Ravulizumab Treatment in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (NCT05131204)Regeneron Pharmaceuticals2022-10-06
A Study of the Incidence of Intraocular Inflammation and Suspected Endophthalmitis Among Patients Treated With Aflibercept, Vial and Pre-filled Syringe, 2014-2022 (NCT05791695)Regeneron Pharmaceuticals2022-09-16
A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Participants With Multiple Myeloma That is Resistant to Current Standard of Care Treatments (NCT05137054)Regeneron Pharmaceuticals2022-08-17
Efficacy of the Anti-Bet v 1 Monoclonal Antibodies (Given Subcutaneously) to Reduce Allergic Rhinitis and Conjunctivitis Symptoms and Skin Test Reactivity Upon Exposure to Birch Allergen in Adult Participants (NCT05430919)Regeneron Pharmaceuticals2022-08-15
A Study to Learn How Safe and Tolerable Vonsetamig is in Adult Patients With Chronic Kidney Disease (CKD) Who Need Kidney Transplantation and Are Highly Sensitized to Human Leukocyte Antigen (HLA) (NCT05092347)Regeneron Pharmaceuticals2022-08-02
Clinical Study of Fianlimab in Combination With Cemiplimab Versus Pembrolizumab in Adolescent and Adult Patients With Previously Untreated Unresectable Locally Advanced or Metastatic Melanoma (NCT05352672)Regeneron Pharmaceuticals2022-07-14
REGN5381 in Heart Failure Adult Participants With Elevated Pulmonary Capillary Wedge Pressure (NCT05353166)Regeneron Pharmaceuticals2022-06-30
Real-World Clinical Outcomes in Adult Patients Who Initiate Systemic Treatment for Relapsed or Refractory Follicular Lymphoma (NCT05338879)Regeneron Pharmaceuticals2022-06-22
Real-World Clinical Outcomes in Adult Patients Who Initiate Systemic Treatment for Relapsed/Refractory Diffuse Large B-Cell Lymphoma (NCT05338892)Regeneron Pharmaceuticals2022-06-22
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN9035 in Healthy Adult Volunteers and Mildly Hypertensive Participants (NCT05291546)Regeneron Pharmaceuticals2022-04-13
Safety and Tolerability of Regeneron Anti-SARS-CoV-2 Monoclonal Antibody/Ies in Adult Healthy Volunteers as Related to COVID-19 (NCT05293678)Regeneron Pharmaceuticals2022-04-12
A Study to Examine the Effects of the Leptin Receptor (LEPR) Agonist Antibody REGN4461 in Adult Patients With Familial Partial Lipodystrophy (FPLD) (NCT05088460)Regeneron Pharmaceuticals2022-02-28
Neuropsychologic Assessments of Dupilumab-Treated Adolescent Participants With Moderate-to-Severe Atopic Dermatitis (NCT05203380)Regeneron Pharmaceuticals2022-01-27
A Study of bbT369 in Relapsed and/or Refractory B Cell Non-Hodgkin's Lymphoma (NHL) (NCT05169489)Regeneron Pharmaceuticals2022-01-24
COVID-19 Study Assessing the Safety and Tolerability of Co-Formulated Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (Casirivimab+Imdevimab) in Adult Volunteers (NCT05181683)Regeneron Pharmaceuticals2022-01-07
COVID-19 Study of Pharmacokinetics, Safety, Tolerability, and Efficacy of Intravenous Anti-Spike(s) SARS-CoV-2 Monoclonal Antibodies (Casirivimab+Imdevimab) for the Treatment of Pediatric Patients Hospitalized Due to COVID-19 (NCT05092581)Regeneron Pharmaceuticals2021-12-16
A Study to Test How Safe Pozelimab and Cemdisiran Combination Therapy and Cemdisiran Alone Are and How Well They Work in Adult Patients With Generalized Myasthenia Gravis (NCT05070858)Regeneron Pharmaceuticals2021-12-14
Genetic Data Collection in Adult Participants to Identify Genetic Variants of Known Importance in Non-alcoholic Steatohepatitis (NASH) (NCT05423327)Regeneron Pharmaceuticals2021-12-09
A Trial To Find Out If Vidutolimod Together With Cemiplimab Is Safe And If It Works In Adult Participants With Advanced Cancer Or Metastatic Cancer (NCT04916002)Regeneron Pharmaceuticals2021-11-30
A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer (NCT05125016)Regeneron Pharmaceuticals2021-11-30
Study of REGN5093-M114 (METxMET Antibody-Drug Conjugate) in Adult Patients With Mesenchymal Epithelial Transition Factor (MET) Overexpressing Advanced Cancer (NCT04982224)Regeneron Pharmaceuticals2021-11-09
COVID-19 Study to Evaluate Safety, Tolerability, and Efficacy of REGN14256+Imdevimab for the Treatment of COVID-19 Adult and Adolescent Patients Without Risk Factors for Progression to Severe Disease (NCT05081388)Regeneron Pharmaceuticals2021-11-08
Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN9933 in Adult Healthy Volunteers (NCT05102136)Regeneron Pharmaceuticals2021-10-27
A Study to Evaluate Efficacy and Safety of Casirivimab+Imdevimab (Monoclonal Antibodies) for Prevention of COVID-19 in Immunocompromised Adolescents and Adults (NCT05074433)Regeneron Pharmaceuticals2021-10-25
Study to Assess the Efficacy and Safety of Garetosmab in Japanese Adult Patients With Fibrodysplasia Ossificans Progressiva (FOP) (NCT04577820)Regeneron Pharmaceuticals2021-10-13
Study Assessing Long-teRm Outcomes of dupiluMAb (DUPIXENT®) Treatment in Adult Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP) (NCT04959448)Regeneron Pharmaceuticals2021-08-12
A Study to Examine the Safety, Tolerability and Biological Effects of Single Doses of Subcutaneously and Intravenously Administered Pozelimab as Monotherapy and in Combination With Single Doses of Subcutaneously Administered Cemdisiran in Adult Japanese Healthy Volunteers (NCT04940364)Regeneron Pharmaceuticals2021-08-04
Pozelimab and Cemdisiran Combination Treatment in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Who Have Received Pozelimab Monotherapy (NCT04811716)Regeneron Pharmaceuticals2021-07-29
Pozelimab and Cemdisiran Combination Therapy in Adult Participants With Paroxysmal Nocturnal Hemoglobinuria Who Switch From Eculizumab Therapy (NCT04888507)Regeneron Pharmaceuticals2021-07-08
Cemiplimab and ISA101b Vaccine in Adult Participants With Recurrent/Metastatic Human Papillomavirus (HPV)16 Cervical Cancer Who Have Experienced Disease Progression After First Line Chemotherapy (NCT04646005)Regeneron Pharmaceuticals2021-06-28
COVID-19 Study to Assess Immunogenicity, Safety, and Tolerability of Moderna mRNA-1273 Vaccine Administered With Casirivimab+Imdevimab in Healthy Adult Volunteers (NCT04852978)Regeneron Pharmaceuticals2021-04-29
A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult and Adolescent Patients With Moderate-to-Severe Atopic Hand and Foot Dermatitis (Liberty-AD-HAFT) (NCT04417894)Regeneron Pharmaceuticals2021-04-14
CMP-001 in Combination With Nivolumab in Subjects With Advanced Melanoma (NCT04698187)Regeneron Pharmaceuticals2021-03-11
Observational Study of Conjunctivitis in the Setting of DUPIXENT® Treatment for Atopic Dermatitis (NCT04287608)Regeneron Pharmaceuticals2021-03-10
CMP-001 in Combination With Nivolumab Compared to Nivolumab Monotherapy in Subjects With Advanced Melanoma (NCT04695977)Regeneron Pharmaceuticals2021-02-24
Extension Study to Evaluate the Long-Term Outcomes of Pediatric Patients Who Received Treatment for Retinopathy of Prematurity in the VGFTe-ROP-1920 Study (Acronym: Butterfleye Next) (NCT04515524)Regeneron Pharmaceuticals2021-02-05
CMP-001 in Combination With Pembrolizumab in Subjects With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (NCT04633278)Regeneron Pharmaceuticals2021-01-21
Study to Assess the Efficacy of Anti-Bet v 1 Monoclonal Antibodies in Adults to Reduce Symptoms of Seasonal Allergic Rhinitis (NCT04709575)Regeneron Pharmaceuticals2021-01-14
REGN7257 in Adult Patients With Severe Aplastic Anemia That Is Refractory to or Relapsed on Immunosuppressive Therapy (NCT04409080)Regeneron Pharmaceuticals2021-01-13
COVID-19 Study Assessing the Virologic Efficacy of REGN10933+REGN10987 Across Different Dose Regimens in Adult Outpatients With SARS-CoV-2 Infection (NCT04666441)Regeneron Pharmaceuticals2020-12-15
A Study to Find Out How Safe REGN5668 is and How Well it Works In Adult Women When Given With Either Cemiplimab, or Cemiplimab + Fianlimab, or Ubamatamab (NCT04590326)Regeneron Pharmaceuticals2020-12-08
Ascending Dose Study of the Safety and Tolerability of REGN6490 in Healthy Volunteers (NCT04616079)Regeneron Pharmaceuticals2020-11-19
Study of the Safety, Tolerability, and Pharmacokinetics of REGN6490 in Healthy Japanese Adult Volunteers (NCT04616105)Regeneron Pharmaceuticals2020-11-18
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Pozelimab in Combination With Cemdisiran in Healthy Adult Volunteers (NCT04601844)Regeneron Pharmaceuticals2020-11-16
Anti-PD-1 Antibody Treatment With Cemiplimab and Radiotherapy in Early-stage Classical Hodgkin Lymphoma (NCT04373083)Regeneron Pharmaceuticals2020-11-15
T Cell Receptor (TCR) Sequencing and Transcriptional Profiling in Adult Celiac Disease Patients Undergoing Gluten Challenge (NCT04614571)Regeneron Pharmaceuticals2020-11-02
A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients With Bullous Pemphigoid (NCT04206553)Regeneron Pharmaceuticals2020-10-28
Study of REGN6569 and Cemiplimab in Adult Patients With Advanced Solid Tumor Malignancies (NCT04465487)Regeneron Pharmaceuticals2020-10-05
Investigating Treatment With Dupilumab in Patients With Allergic Bronchopulmonary Aspergillosis (ABPA) (LIBERTY ABPA AIRED) (NCT04442269)Regeneron Pharmaceuticals2020-09-15
Study to Investigate the Efficacy and Safety of Dupilumab in Pediatric Patients With Active Eosinophilic Esophagitis (EoE) (NCT04394351)Regeneron Pharmaceuticals2020-09-01
Study Assessing the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Repeated Subcutaneous Doses of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (REGN10933+REGN10987) in Adult Volunteers as Related to COVID-19 (NCT04519437)Regeneron Pharmaceuticals2020-07-26
COVID-19 Study Assessing the Efficacy and Safety of Anti-Spike SARS CoV-2 Monoclonal Antibodies for Prevention of SARS CoV-2 Infection Asymptomatic in Healthy Adults and Adolescents Who Are Household Contacts to an Individual With a Positive SARS-CoV-2 RT-PCR Assay (NCT04452318)Regeneron Pharmaceuticals2020-07-13
Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease (NCT04429503)Regeneron Pharmaceuticals2020-06-29
Evaluate the Efficacy and Safety of Evinacumab in Pediatric Patients With Homozygous Familial Hypercholesterolemia (NCT04233918)Regeneron Pharmaceuticals2020-06-29
Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for the Treatment of Ambulatory Adult and Pediatric Patients With COVID-19 (NCT04425629)Regeneron Pharmaceuticals2020-06-16
Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies for Hospitalized Adult Patients With COVID-19 (NCT04426695)Regeneron Pharmaceuticals2020-06-10
Evaluation of the Efficacy and Safety of Sarilumab in Hospitalized Patients With COVID-19 (NCT04315298)Regeneron Pharmaceuticals2020-03-18
Study of Cemiplimab in Patients With Type of Skin Cancer Stage II to IV Cutaneous Squamous Cell Carcinoma (NCT04154943)Regeneron Pharmaceuticals2020-03-10
Registry of Asthma Patients Initiating DUPIXENT® (NCT04287621)Regeneron Pharmaceuticals2020-03-02
Open-Label Efficacy and Safety Study of Pozelimab in Patients With CD55-Deficient Protein-Losing Enteropathy (CHAPLE Disease) (NCT04209634)Regeneron Pharmaceuticals2020-01-27
Study of REGN4461, a Leptin Receptor Agonist Antibody, in Patients With Generalized Lipodystrophy (NCT04159415)Regeneron Pharmaceuticals2020-01-07
A Study of REGN5093 in Adult Patients With Mesenchymal Epithelial Transition Factor (MET)-Altered Advanced Non-Small Cell Lung Cancer (NCT04077099)Regeneron Pharmaceuticals2020-01-07
REGN3918 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) to Evaluate Its Long Term Safety, Efficacy and Tolerability. (NCT04162470)Regeneron Pharmaceuticals2019-12-03
A Study to Assess the Anti-Tumor Activity and Safety of Odronextamab in Adult Patients With B-cell Non-Hodgkin Lymphoma Who Have Been Previously Treated With Other Cancer Therapies (NCT03888105)Regeneron Pharmaceuticals2019-11-13
Safety, Tolerability, and Efficacy of Aflibercept in Patients With Neovascular Age-Related Macular Degeneration (NCT04126317)Regeneron Pharmaceuticals2019-11-04
An Observational Retrospective Cohort Study Being Conducted in Women With Atopic Dermatitis (AD) (NCT03936335)Regeneron Pharmaceuticals2019-09-30
First In Human (FIH) Study of REGN5459 in Adult Patients With Relapsed or Refractory Multiple Myeloma (MM) (NCT04083534)Regeneron Pharmaceuticals2019-09-26
A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors (NCT03972657)Regeneron Pharmaceuticals2019-08-12
Neoadjuvant Cemiplimab for the Treatment of Resectable NSCLC, HCC, and HNSCC in Adult Patients (NCT03916627)Regeneron Pharmaceuticals2019-07-23
CemiplimAb Survivorship Epidemiology (NCT03836105)Regeneron Pharmaceuticals2019-06-27
Study of Adjuvant Cemiplimab Versus Placebo After Surgery and Radiation Therapy in Patients With High Risk Cutaneous Squamous Cell Carcinoma (NCT03969004)Regeneron Pharmaceuticals2019-06-04
Study to Assess the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Effects of a Single Dose of REGN5713-5714-5715 in Healthy Adult Participants (NCT03969849)Regeneron Pharmaceuticals2019-06-03
A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee (NCT03956550)Regeneron Pharmaceuticals2019-05-21
Study to Evaluate the Efficacy and Safety of REGN3918 in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) (NCT03946748)Regeneron Pharmaceuticals2019-05-16
Intralesional Cemiplimab for Adult Patients With Cutaneous Squamous Cell Carcinoma or Basal Cell Carcinoma (NCT03889912)Regeneron Pharmaceuticals2019-04-11
Study to Evaluate Arthroplasty Specimens for Osteoarthritis of the Knee and Hip (NCT03949673)Regeneron Pharmaceuticals2019-04-08
Study to Evaluate Dupilumab Monotherapy in Pediatric Patients With Peanut Allergy (NCT03793608)Regeneron Pharmaceuticals2019-03-12
Safety and Efficacy of REGN2477+REGN1033 in Patients With Sporadic Inclusion Body Myositis (NCT03710941)Regeneron Pharmaceuticals2019-02-19
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