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Novartis Pharmaceuticals

2,688 clinical trials · Sponsor

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RecordFirmDate
Study of [68Ga]-FF58 in Patients With Selected Solid Tumors Expected to Overexpress αvβ3 and αvβ5 Integrins. (NCT04712721)Novartis Pharmaceuticals2021-10-14
Asciminib Treatment Optimization in ≥ 3rd Line CML-CP (NCT04948333)Novartis Pharmaceuticals2021-10-13
A Study of Oral Asciminib Versus Other TKIs in Adult Patients With Newly Diagnosed Ph+ CML-CP (NCT04971226)Novartis Pharmaceuticals2021-10-06
Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Giant Cell Arteritis (GCA) (NCT04930094)Novartis Pharmaceuticals2021-10-06
Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis (NCT04926818)Novartis Pharmaceuticals2021-10-05
Retrospective Assessment of Adverse Events-related Healthcare Resource Utilization and Costs of Immune Checkpoint Inhibitor and Targeted Therapy for Adjuvant Treatment of Melanoma (NCT05714371)Novartis Pharmaceuticals2021-10-02
Real-World Assessment of Clinical Outcomes in Metastatic NSCLC Patients With MET Exon 14 Skipping Mutation and Brain Metastases Treated With Capmatinib (NCT05675683)Novartis Pharmaceuticals2021-10-01
Study of Efficacy and Safety of NIS793 in Combination With Standard of Care (SOC) Chemotherapy in First-line Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC) - daNIS-2 (NCT04935359)Novartis Pharmaceuticals2021-09-30
Study of Diagnostic Performance of [18F]CTT1057 in BCR (NCT04838613)Novartis Pharmaceuticals2021-09-30
Nationwide Trends in Incidence, Healthcare Utilization, and Mortality in Hospitalized Acute Myocardial Infarction Patients in Taiwan (NCT05974397)Novartis Pharmaceuticals2021-09-30
A Prospective Multicenter Study for the Assessment of Treatment Patterns, Effectiveness and Safety of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis in a Real-world Setting in China (NCT04894890)Novartis Pharmaceuticals2021-09-26
Study of Effect of CSJ117 on Symptoms, Pharmacodynamics and Safety in Patients With COPD (NCT04882124)Novartis Pharmaceuticals2021-09-24
Study Evaluating Efficacy and Safety of Capmatinib in Combination With Osimertinib in Adult Subjects With Non-small Cell Lung Cancers as Second Line Therapy (NCT04816214)Novartis Pharmaceuticals2021-09-22
Study of Safety, Tolerability and Efficacy of DFV890 in Participants With Familial Cold Auto-inflammatory Syndrome (FCAS) (NCT04868968)Novartis Pharmaceuticals2021-09-20
Study of Efficacy, Safety and Tolerability of DFV890 in Patients With Knee Osteoarthritis (NCT04886258)Novartis Pharmaceuticals2021-09-20
A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy (NCT04557462)Novartis Pharmaceuticals2021-09-20
Sabatolimab as a Treatment for Patients With Acute Myeloid Leukemia and Presence of Measurable Residual Disease After Allogeneic Stem Cell Transplantation. (NCT04623216)Novartis Pharmaceuticals2021-09-14
Risk Perception in Multiple Sclerosis (NCT05528666)Novartis Pharmaceuticals2021-09-09
Safety and Efficacy of Intravenous OAV101 (AVXS-101) in Pediatric Patients With Spinal Muscular Atrophy (SMA) (NCT04851873)Novartis Pharmaceuticals2021-09-08
Study of Safety of CSJ117 in Participants With Moderate to Severe Uncontrolled Asthma (NCT04946318)Novartis Pharmaceuticals2021-09-08
Study of Diagnostic Performance of [18F]CTT1057 for PSMA-positive Tumors Detection (NCT04838626)Novartis Pharmaceuticals2021-09-07
A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer (NCT05067140)Novartis Pharmaceuticals2021-09-02
Retrospective Analysis of Patients Re-treated With Lutetium-177 DOTATATE (Lutathera®) (NCT05816720)Novartis Pharmaceuticals2021-09-01
Characteristics of Patients With Sickle Cell Disease (NCT05494541)Novartis Pharmaceuticals2021-08-30
A Safety and Efficacy Study of Anti-inflammatory (Canakinumab) and Cartilage Stimulating (LNA043) Drugs Injected Into the Knee Joint of Participants With Knee Osteoarthritis (OA) (NCT04814368)Novartis Pharmaceuticals2021-08-27
Analysis of Imaging Features From Patients Treated With Brolucizumab in the Post-marketing Setting With Reports of Retinal Vasculitis and/or Retinal Vascular Occlusion (NCT05657158)Novartis Pharmaceuticals2021-08-23
Regulatory Post-Marketing Surveillance Study for Brolucizumab (NCT04985487)Novartis Pharmaceuticals2021-08-18
Psoriatic Disease and Related Manifestations; Real World Evidence in Brazilian Secukinumab Environment (NCT06666114)Novartis Pharmaceuticals2021-08-03
Care Pathway and Associated Costs of Patients Treated With CAR T-cells Based on SNDS Data (NCT06392763)Novartis Pharmaceuticals2021-08-03
Sacubitril/Valsartan Treated Adult Patients With Chronic Heart Failure (NCT05613140)Novartis Pharmaceuticals2021-08-02
Patient Characteristics, Associated Factors, and Clinical Outcomes of Prescribing Encorafenib and Binimetenib Versus Dabrafenib and Trametinib Among BRAF v600 Mutated Metastatic Melanoma Patients (NCT05806268)Novartis Pharmaceuticals2021-07-30
Patient Characteristics and Treatment Patterns From Early Crizanlizumab Use in Real-world Setting: Preliminary Analysis From Select Sickle Cell Centers (NCT05833022)Novartis Pharmaceuticals2021-07-30
A Study of 177Lu-FAP-2286 in Advanced Solid Tumors (NCT04939610)Novartis Pharmaceuticals2021-07-30
Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy. (NCT04817618)Novartis Pharmaceuticals2021-07-28
Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria (NCT04747613)Novartis Pharmaceuticals2021-07-27
A Prospective Observational Study to Describe Clinical Outcomes, Treatment Patterns, Patients Characteristics Among Patients With HR+/HER2- Advanced BC Initiating Treatment With Risarg®, Piqray®, Endocrine Therapy or Chemotherapy in Routine Clinical Practice in Russia (NCT04943497)Novartis Pharmaceuticals2021-07-27
Open Label Randomized Multicenter to Assess Efficacy & Tolerability of Ofatumumab 20mg vs. First Line DMT in RMS (NCT04788615)Novartis Pharmaceuticals2021-07-23
A Real-world Study of Tuberculosis Incidence in AS, PsA, or PsO Patients Treated With Secukinumab in Brazil (NCT06715254)Novartis Pharmaceuticals2021-07-23
Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected (NCT04729387)Novartis Pharmaceuticals2021-07-22
Efficacy and Safety Study of Secukinumab in Chinese Participants With Non-radiographic Axial Spondyloarthritis (NCT04732117)Novartis Pharmaceuticals2021-07-21
Study to Assess Safety, Tolerability, and Interactions of Cocaine and Oral AFQ056 (NCT04771143)Novartis Pharmaceuticals2021-07-21
Study of Efficacy and Safety of MIJ821 in Addition to Comprehensive Standard of Care on the Rapid Reduction of Symptoms of Major Depressive Disorder in Subjects Who Have Suicidal Ideation With Intent (NCT04722666)Novartis Pharmaceuticals2021-07-20
Study of Efficacy and Safety of Twice Daily Oral Iptacopan (LNP023) in Adult PNH Patients Who Are Naive to Complement Inhibitor Therapy (NCT04820530)Novartis Pharmaceuticals2021-07-19
Real-world Outcomes of Aplastic Anemia Patients Treated With Eltrombopag: A Medical Claims Database Study (NCT06991894)Novartis Pharmaceuticals2021-07-14
An Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease Patients (NCT04662931)Novartis Pharmaceuticals2021-07-14
Efficacy and Safety of Two Different Brolucizumab 6 mg Dosing Regimens in Neovascular Age-related Macular Degeneration (NCT04679935)Novartis Pharmaceuticals2021-07-13
Study in Primary Care Evaluating Inclisiran Delivery Implementation + Enhanced Support (NCT04807400)Novartis Pharmaceuticals2021-07-07
A Dose-ranging Study to Evaluate the Safety and Efficacy of UNR844 in Subjects With Presbyopia. (NCT04806503)Novartis Pharmaceuticals2021-06-30
Proof of Concept Study of Binocular Videogames Versus Patching for Amblyopia (NCT04784390)Novartis Pharmaceuticals2021-06-30
Special Drug-use Surveillance for Kesimpta for s.c. Injection 20 mg Pen (NCT04940065)Novartis Pharmaceuticals2021-06-30
A Randomized Study to Evaluate the Effect of an "Inclisiran First" Implementation Strategy Compared to Usual Care in Patients With Atherosclerotic Cardiovascular Disease and Elevated LDL-C Despite Receiving Maximally Tolerated Statin Therapy (VICTORION-INITIATE) (NCT04929249)Novartis Pharmaceuticals2021-06-25
Study of Efficacy and Safety of Secukinumab in Chinese Subjects With Active PsA Compared to Placebo. (NCT04711902)Novartis Pharmaceuticals2021-06-24
Management of LDL-cholesterol With Inclisiran + Usual Care Compared to Usual Care Alone in Participants With a Recent Acute Coronary Syndrome (NCT04873934)Novartis Pharmaceuticals2021-06-24
VOB560-MIK665 Combination First in Human Trial in Patients With Hematological Malignancies (Relapsed/Refractory Non-Hodgkin Lymphoma, Relapsed/Refractory Acute Myeloid Leukemia, or Relapsed/Refractory Multiple Myeloma) (NCT04702425)Novartis Pharmaceuticals2021-06-23
Phase Ib Study of Select Drug Combinations in Patients With Lower Risk MDS (NCT04810611)Novartis Pharmaceuticals2021-06-18
177Lu-PSMA-617 vs. Androgen Receptor-Directed Therapy in the Treatment of Progressive Metastatic Castrate Resistant Prostate Cancer (NCT04689828)Novartis Pharmaceuticals2021-06-15
Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study (NCT04657822)Novartis Pharmaceuticals2021-06-10
A Open-label Study to Assess Response to COVID-19 Vaccine in Multiple Sclerosis Participants Treated With Ofatumumab (NCT04878211)Novartis Pharmaceuticals2021-06-10
Real World Effectiveness, Persistence, Tolerability, and Safety of Ofatumumab in Clinical Practice (NCT06737419)Novartis Pharmaceuticals2021-06-09
An International Prospective Open-label, Randomized, Phase III Study Comparing 177Lu-PSMA-617 in Combination With Standard of Care (SoC), Versus SoC Alone, in Adult Male Patients With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) (NCT04720157)Novartis Pharmaceuticals2021-06-09
Study to Compare the Pharmacokinetics of Mometasone Furoate Alone and in Combination With Indacaterol in Patients ≥ 6 to < 12 Years Old With Asthma (NCT04589663)Novartis Pharmaceuticals2021-06-07
Secukinumab (Cosentyx®) Effectiveness in Axial Spondyloarthritis and Psoriatic Arthritis Patients Using Artificial Intelligence (SpAINET): Spanish Multicenter, Retrospective, Real World Evidence Study (NCT05677542)Novartis Pharmaceuticals2021-06-02
A Study of Sabatolimab in Combination With Azacitidine and Venetoclax in High or Very High Risk MDS Participants (NCT04812548)Novartis Pharmaceuticals2021-05-31
Study of Efficacy, Safety, and Tolerability of LNA043 in Patients With Knee Osteoarthritis (NCT04864392)Novartis Pharmaceuticals2021-05-31
Exploring the Immune Response to SARS-CoV-2 COVID-19 Vaccines in Patients With Relapsing Multiple Sclerosis (RMS) Treated With Ofatumumab (NCT04869358)Novartis Pharmaceuticals2021-05-27
Open-label Extension Study for CLCZ696G2301 (PARADISE-MI) (NCT04637555)Novartis Pharmaceuticals2021-05-26
Asciminib in Monotherapy for Chronic Myeloid Leukemia in Chronic Phase (CML-CP) With and Without T315I Mutation (NCT04666259)Novartis Pharmaceuticals2021-05-25
Study of Efficacy and Safety of Eltrombopag in Lower-risk MDS Patients With Platelet Transfusion Dependence (NCT04797000)Novartis Pharmaceuticals2021-05-25
A Multicenter Study to Assess Response to COVID-19 Vaccine in Multiple Sclerosis Participants Treated With Ofatumumab (NCT04847596)Novartis Pharmaceuticals2021-05-21
Study of Capmatinib in Chinese Adult Patients With Advanced Non-small Cell Lung Cancer Harboring MET Exon 14 Skipping Mutation (NCT04677595)Novartis Pharmaceuticals2021-05-17
Study of Safety, Tolerability, and Pharmacokinetics of INE963 in Healthy Participants (NCT04896632)Novartis Pharmaceuticals2021-05-13
Time and Motion Study for Ocrelizumab and Ofatumumab Administration in Relapsing Multiple Sclerosis (NCT04676555)Novartis Pharmaceuticals2021-05-11
Observational Study to Evaluate Fluid Resolution and Effectiveness of Brolucizumab for nAMD in Portugal (NCT04764656)Novartis Pharmaceuticals2021-05-10
A Dose Finding, Efficacy and Safety Study of Ensovibep (MP0420) in Ambulatory Adult Patients With Symptomatic COVID-19 (NCT04828161)Novartis Pharmaceuticals2021-05-10
French Study to Highlight the Unmet Treatment Needs of 3L+ CP-CML and With T315I-mutated CML Patients (NCT05619978)Novartis Pharmaceuticals2021-05-03
Retrospective Assessment of AE-Related Healthcare Resource Utilization and Costs of Immune Checkpoint Inhibitor and Targeted Therapy for Adjuvant Treatment of Melanoma (NCT05874817)Novartis Pharmaceuticals2021-05-01
Real-World Disease Management and Outcomes in Chronic Myeloid Leukaemia (NCT05893836)Novartis Pharmaceuticals2021-04-27
Study of Efficacy and Safety of SAF312 Eye Drops in Subjects With Post-operative Corneal Induced Chronic Pain (CICP) (NCT04630158)Novartis Pharmaceuticals2021-04-21
A Study to Assess the Efficacy and Safety of CMK389 in Patients With Moderate to Severe Atopic Dermatitis. (NCT04836858)Novartis Pharmaceuticals2021-04-20
Study Assessing the Efficacy, Safety and PK of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (NCT04589650)Novartis Pharmaceuticals2021-04-19
Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC) (NCT04792567)Novartis Pharmaceuticals2021-04-19
Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2) (NCT04603495)Novartis Pharmaceuticals2021-04-09
A Study to Evaluate the Therapeutic Benefit of Tisagenlecleucel Compared to Existing Standard of Care in German Adult Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (NCT07103486)Novartis Pharmaceuticals2021-04-01
Study of Efficacy and Safety of Canakinumab in Japanese Patients With AOSD (NCT04717635)Novartis Pharmaceuticals2021-03-30
Ribociclib in Combination With Non-steroidal Aromatase Inhibitors in Patients With Advanced Breast Cancer (NCT05569187)Novartis Pharmaceuticals2021-03-23
Impact of Secukinumab on Clinical and Patient Reported Outcomes in Patients With Psoriasis (NCT05513014)Novartis Pharmaceuticals2021-03-21
Evaluating the Safety of Myfortic (Mycophenolate Sodium) in Patients With Lupus Nephritis (NCT04645589)Novartis Pharmaceuticals2021-03-16
Atrasentan in Patients With Proteinuric Glomerular Diseases (NCT04573920)Novartis Pharmaceuticals2021-03-15
Italian Prospective Observational Study Assessing the Effectiveness and Outcomes Associated With Lutathera Treatment in GEP-NETs (NCT04727723)Novartis Pharmaceuticals2021-03-09
Study Conducted Among Patients With CML (NCT05476562)Novartis Pharmaceuticals2021-03-08
Special Drug Use Surveillance for Entresto Tablets (NCT04781881)Novartis Pharmaceuticals2021-03-04
Study of Efficacy and Safety of Inclisiran in Asian Participants With Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD High Risk and Elevated Low Density Lipoprotein Cholesterol (LDL-C) (NCT04765657)Novartis Pharmaceuticals2021-03-01
Study of Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inclisiran in Chinese Participants With Elevated Serum LDL-C (NCT04774003)Novartis Pharmaceuticals2021-02-26
Effectiveness and Safety of Omalizumab in Children With Allergic Asthma. (NCT05424523)Novartis Pharmaceuticals2021-02-25
Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation (NCT04699188)Novartis Pharmaceuticals2021-02-24
A Non-interventional Study to Assess the Influence of Automated Optical Coherence Tomography Image Enrichment With Segmentation Information on Disease Activity Assessment in Patients Treated With Licensed Anti- VEGF Injections (NCT04662944)Novartis Pharmaceuticals2021-02-23
Study of Efficacy and Safety of Fingolimod (Gilenya) 0.5 mg in Chinese Patients With Relapsing Multiple Sclerosis (RMS) Patients (NCT04667949)Novartis Pharmaceuticals2021-02-20
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy (NCT04539041)Novartis Pharmaceuticals2021-02-16
Study to Evaluate Efficacy and Safety of Inclisiran in Adolescents With Homozygous Familial Hypercholesterolemia (NCT04659863)Novartis Pharmaceuticals2021-02-16
Efficacy, Safety and Tolerability of KAF156 in Combination With Lumefantrine Solid Dispersion Formulation (LUM-SDF) in Pediatric Population With Uncomplicated Plasmodium Falciparum Malaria (NCT04546633)Novartis Pharmaceuticals2021-02-16
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