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Novartis Pharmaceuticals

2,688 clinical trials · Sponsor

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RecordFirmDate
A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy (NCT05592990)Novartis Pharmaceuticals2023-06-14
A Post Approval Commitment Study on Tabrecta® (Capmatinib) in South Korea (NCT05703516)Novartis Pharmaceuticals2023-06-12
Epidemiology and Treatment of HR+/HER2- Breast Cancer in England (NCT07498413)Novartis Pharmaceuticals2023-06-08
A Study About the Use of Omalizumab in the Treatment of Food Allergy and Anaphylaxis (NCT07027163)Novartis Pharmaceuticals2023-06-01
Safety and Efficacy of RHH646 for Knee Osteoarthritis (NCT05816395)Novartis Pharmaceuticals2023-05-31
Real-World Treatment Patterns and Outcomes Among Patients With Chronic Myeloid Leukemia in Earlier Lines of Therapy (NCT06692803)Novartis Pharmaceuticals2023-05-23
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics and Dosimetry of [177Lu]Lu-PSMA-617 in Chinese Adult Male Patients With Progressive PSMA-Positive mCRPC (NCT05670106)Novartis Pharmaceuticals2023-05-16
Real World, Pharmacy-assessed Adherence to New Onset Entresto® (Sacubitril/Valsartan) in Patients With Chronic Heart Failure (NCT05870709)Novartis Pharmaceuticals2023-05-15
A Study to Evaluate the Efficacy and Safety of QMF149 (Indacaterol Acetate/Mometasone Furoate) Versus Budesonide in Children From 6 to Less Than 12 Years of Age With Asthma (NCT05562466)Novartis Pharmaceuticals2023-05-11
Dose Optimization and Expansion Study of DFV890 in Adult Patients With Myeloid Diseases (NCT05552469)Novartis Pharmaceuticals2023-05-08
A Study Evaluating [177Lu]Lu-PSMA-617 vs. a Change of Androgen Receptor-directed Therapy in Taxane Treatment Naive Chinese Male Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (NCT05658003)Novartis Pharmaceuticals2023-05-05
A Phase IV Study of Safety and Efficacy of Everolimus in Taiwanese Patients With Tuberous Sclerosis Complex Who Have Renal Angiomyolipoma (TSC-AML) (NCT05252585)Novartis Pharmaceuticals2023-05-01
Long-term Extension Study of Ligelizumab in Food Allergy (NCT05678959)Novartis Pharmaceuticals2023-04-27
Phase 3 Study to Evaluate Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 2) (NCT05624749)Novartis Pharmaceuticals2023-04-21
A Multicenter, Open-label Phase 3 Study: Ambulatory Blood Pressure Monitoring in Adult Patients With Chronic Spontaneous Urticaria Inadequately Controlled by H1-antihistamines Treated With Remibrutinib up to 12 Weeks. (NCT05795153)Novartis Pharmaceuticals2023-04-05
Characterizing Guideline Adoption and Treatment Quality in Clinical Routine of German HFrEF Care (NCT06004453)Novartis Pharmaceuticals2023-04-03
A Study of Peptide Receptor Radionuclide Therapy (PRRT) Use in Neuroendocrine Tumor (NET) Patients in Germany (NCT07653126)Novartis Pharmaceuticals2023-04-03
A Study to Describe a Group of Spanish Patients With FMF and to Identify Suboptimally Treated Patients With Minimal Disease Activity and Its Impact on Quality of Life (NCT06923124)Novartis Pharmaceuticals2023-03-30
Extension Study of Efficacy and Safety of LTP001 in Pulmonary Arterial Hypertension Participants (NCT05764265)Novartis Pharmaceuticals2023-03-27
Phase III Study of Efficacy and Safety of Secukinumab Versus Placebo, in Combination With Glucocorticoid Taper Regimen, in Patients With Polymyalgia Rheumatica (PMR) (NCT05767034)Novartis Pharmaceuticals2023-03-22
Efficacy and Safety of Inclisiran as Monotherapy in Patients With Primary Hypercholesterolemia Not Receiving Lipid-lowering Therapy. (NCT05763875)Novartis Pharmaceuticals2023-03-15
Study of Efficacy, Safety, Tolerability and Pharmacokinetics of MIJ821 in Participants With Treatment- Resistant Depression (TRD) (NCT05454410)Novartis Pharmaceuticals2023-03-13
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients. (NCT05739383)Novartis Pharmaceuticals2023-03-09
A Study to Evaluate the Safety of QCZ484 in Healthy and Mild Hypertensive Subjects (NCT06905327)Novartis Pharmaceuticals2023-03-08
A Study to Evaluate the Impact of Long-term Digital Education vs Standard of Care on LDL-C Levels in Post Myocardial Infarction Patients (NCT06548555)Novartis Pharmaceuticals2023-03-08
A Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of TIN816 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery. (NCT05524051)Novartis Pharmaceuticals2023-03-03
Study to Identify and Describe Predictive Factors for Thromboembolic Events in Patients With High-risk Polycythemia Vera (NCT05548062)Novartis Pharmaceuticals2023-03-02
Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1) (NCT05639114)Novartis Pharmaceuticals2023-03-02
A Real-world Study of the Effectiveness of Tisagenlecleucel in Acute Lymphoblastic Leukemia Patients (NCT07039383)Novartis Pharmaceuticals2023-03-01
A Real-world Study of the Safety of Hypertension Medication Therapy in Japanese Patients With Naïve Hypertension (NCT06683768)Novartis Pharmaceuticals2023-02-28
An Open-label, Study to Assess Safety, Efficacy and Cellular Kinetics of YTB323 in Severe, Refractory Systemic Lupus Erythematosus (NCT05798117)Novartis Pharmaceuticals2023-02-28
Roll-over Study for Patients Who Have Completed a Prior Novartis-sponsored Sabatolimab (MBG453) Study and Are Judged by the Investigator to Benefit From Continued Treatment With Sabatolimab. (NCT05201066)Novartis Pharmaceuticals2023-02-28
Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants (NCT05469360)Novartis Pharmaceuticals2023-02-23
A Study of Siremadlin Alone and in Combination With Donor Lymphocyte Infusion in Acute Myeloid Leukemia Post-allogeneic Stem Cell Transplant (NCT05447663)Novartis Pharmaceuticals2023-02-23
Long-term Safety and Tolerability of Inclisiran in Participants With HeFH or HoFH Who Have Completed the Pediatric ORION-16, ORION-13, ORION-20, or ORION-19 Studies (NCT05682378)Novartis Pharmaceuticals2023-02-10
Study Assessing the Efficacy and Safety of a Personalized Monotherapy Regimen of Brolucizumab in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (NCT05666804)Novartis Pharmaceuticals2023-02-06
Effectiveness of Entresto (Sacubitril/Valsartan) in Japanese Patients With Hypertension (NCT06604897)Novartis Pharmaceuticals2023-01-31
Patterns of Inclisiran Use in the Real World: An Analysis of US Databases (NCT07023445)Novartis Pharmaceuticals2023-01-20
A 24-week Study Evaluating the Effectiveness and Safety of Lucentis® 0.2mg in Retinopathy of Prematurity Participants in China (NCT05576792)Novartis Pharmaceuticals2023-01-13
Regulatory Post-Marketing Surveillance of Xolair® for Chronic Rhinosinusitis With Nasal Polyps (NCT05626257)Novartis Pharmaceuticals2023-01-12
Phase IIIb, Open-label, Multi-center Study to Evaluate Safety, Tolerability and Efficacy of OAV101 Administered Intrathecally to Participants With SMA Who Discontinued Treatment With Nusinersen or Risdiplam (NCT05386680)Novartis Pharmaceuticals2023-01-12
An Open-label, Adaptive Design, Positron Emission Tomography Study in Healthy Male Participants to Characterize Receptor Occupancy by MIJ821 in the Brain (NCT05666687)Novartis Pharmaceuticals2023-01-11
The 'Wearing Off' Effect of DMT (NCT05627271)Novartis Pharmaceuticals2023-01-10
Kesimpta (Ofatumumab) Pregnancy Registry (NCT05634967)Novartis Pharmaceuticals2023-01-05
A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia (NCT05648968)Novartis Pharmaceuticals2022-12-30
Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors (NCT05429502)Novartis Pharmaceuticals2022-12-27
A Real-world Study of Indian Patients With Advanced Breast Cancer Treated With Ribociclib (NCT07363434)Novartis Pharmaceuticals2022-12-21
Long-term Follow-up of Patients With Spinal Muscular Atrophy Treated With OAV101 in Clinical Trials (NCT05335876)Novartis Pharmaceuticals2022-12-19
Ribociclib Real-world Treatment Patterns and Clinical Outcomes Among Women With HR+/HER2- Advanced or Metastatic Breast Cancer in France (NCT05697146)Novartis Pharmaceuticals2022-12-13
An Extension Study of Long-term Efficacy, Safety and Tolerability of Remibrutinib in Chronic Spontaneous Urticaria Patients Who Completed Preceding Studies With Remibrutinib (NCT05513001)Novartis Pharmaceuticals2022-12-09
Characterizing the Use of Ofatumumab in a Real World Setting (NCT05090033)Novartis Pharmaceuticals2022-12-08
Study of Efficacy and Safety of JDQ443 Single-agent as First-line Treatment for Patients With Locally Advanced or Metastatic KRAS G12C- Mutated Non-small Cell Lung Cancer With a PD-L1 Expression < 1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutation. (NCT05445843)Novartis Pharmaceuticals2022-12-06
Study of Efficacy and Safety of AIN457/Secukinumab in Patients With Rotator Cuff Tendinopathy (NCT05569174)Novartis Pharmaceuticals2022-12-02
Pharmacokinetics and Safety Study of Siremadlin (HDM201) in Participants With Mild, Moderate and Severe Hepatic Impairment (NCT05599932)Novartis Pharmaceuticals2022-12-02
Pharmacokinetics and Safety of TIN816 in Patients With Sepsis-associated Acute Kidney Injury (NCT05507437)Novartis Pharmaceuticals2022-11-22
A Study to Investigate Tolerability and Efficacy of Asciminib (Oral) Versus Nilotinib (Oral) in Adult Participants (≥18 Years of Age) With Newly Diagnosed Philadelphia Chromosome Positive Chronic Myelogenous Leukemia in Chronic Phase (Ph+ CML-CP) (NCT05456191)Novartis Pharmaceuticals2022-11-21
Incidence of Psoriatic Arthritis Among Psoriasis Patients Newly Initiated With Secukinumab in a US Claims Database and a UK Registry (NCT06172426)Novartis Pharmaceuticals2022-11-17
Asciminib Monotherapy, With Dose Escalation, for 2nd and 1st Line Chronic Myelogenous Leukemia (NCT05384587)Novartis Pharmaceuticals2022-11-11
To Assess the Efficacy of the Investigational Products Compared to Placebo in Participants With IPF (NCT05497284)Novartis Pharmaceuticals2022-11-10
A Proof-of-concept Study to Examine QUC398 in Participants With Knee OA (NCT05462990)Novartis Pharmaceuticals2022-11-09
An Efficacy, Safety, Tolerability and Dose Finding Study of XXB750 in Resistant Hypertension Patients. (NCT05562934)Novartis Pharmaceuticals2022-11-08
A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Hepatic Impairment Compared With Matched Healthy Participants (NCT05753592)Novartis Pharmaceuticals2022-10-31
Study Evaluating Kesimpta® Treatment Effects in Patients With Relapsing Multiple Sclerosis Transitioning From Other Therapies (NCT05566756)Novartis Pharmaceuticals2022-10-28
A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers (NCT05544929)Novartis Pharmaceuticals2022-10-26
Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation (NCT05358249)Novartis Pharmaceuticals2022-10-24
A Randomized, Open, Parallel, Controlled, Multi-center, Interventional, Cross-sectional Study to Evaluate the Detection Rate of Psoriatic Arthritis in Korean Moderate-to-severe Psoriasis Patients, With or Without Active Screening for Arthritis in Psoriasis (ASAP Study) (NCT05758402)Novartis Pharmaceuticals2022-10-20
Study of Efficacy, Safety and Tolerability of Remibrutinib in Adult Participants With an Allergy to Peanuts (NCT05432388)Novartis Pharmaceuticals2022-10-12
Study of MGY825 in Patients With Advanced Non-small Cell Lung Cancer (NCT05275868)Novartis Pharmaceuticals2022-10-05
Treatment Patterns and Real-World Clinical Outcomes in Patients With Advanced NSCLC and MET Exon 14 Skipping Mutation in the United States (NCT06161051)Novartis Pharmaceuticals2022-10-03
Study of PIT565 in Relapsed and/or Refractory B-cell Malignancies (NCT05397496)Novartis Pharmaceuticals2022-10-03
Efficacy and Safety of Secukinumab in Patients With New Onset of Giant Cell Arteritis Who Are in Clinical Remission (NCT05380453)Novartis Pharmaceuticals2022-09-29
Real-World Patient Characteristics, Treatment Patterns, and Clinical Outcomes Among Patients With BRAF-Positive Metastatic Melanoma (NCT06251934)Novartis Pharmaceuticals2022-09-28
Real-World Usage of Asciminib Among Patients With Chronic Myeloid Leukemia in Chronic Phase in the United States Using a Large Claims Database (NCT06148493)Novartis Pharmaceuticals2022-09-20
Study Evaluating LDL-C Change and Adherence to Inclisiran Lipid-lowering Therapy in ASCVD (NCT05399992)Novartis Pharmaceuticals2022-09-12
A Real-world Study to Assess Safety and Effectiveness of Secukinumab in Pediatric Plaque Psoriasis Patients in China (NCT05388916)Novartis Pharmaceuticals2022-09-08
A Study to Evaluate Real-world Brolucizumab Effectiveness and Safety in Japanese Patients With Neovascular Age-related Macular Degeneration (nAMD) (NCT06699914)Novartis Pharmaceuticals2022-09-06
Study of Capmatinib in Indian Patients With MET Exon 14 Skipping Mutation Positive Advanced NSCLC. (NCT05110196)Novartis Pharmaceuticals2022-09-03
Special Drug Use Observational Study With Beovu Kit for Intravitreal Injection (NCT05526729)Novartis Pharmaceuticals2022-09-02
Asciminib Roll-over Study (NCT04877522)Novartis Pharmaceuticals2022-08-30
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Glycopyrronium (Bromide) in Children (6 to Less Than 12 Years) With Asthma (NCT05222529)Novartis Pharmaceuticals2022-08-29
Open-label Extension Study of Efficacy, Safety and Tolerability of Secukinumab in Patients With Active Lupus Nephritis (NCT05232864)Novartis Pharmaceuticals2022-08-22
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Rate of Weekly Lipoprotein Apheresis Sessions in Patients With Hyperlipoproteinemia(a) and Established Cardiovascular Disease in Germany (NCT05305664)Novartis Pharmaceuticals2022-08-19
Study to Demonstrate the Efficacy and Safety of Secukinumab up to 224 Weeks in Subjects With Active Peripheral Spondyloarthritis (pSpA). (NCT05206591)Novartis Pharmaceuticals2022-08-16
Real-World HRU and Costs in DLBCL Pts With Tisa-cel and Axi-cel, a Medicare Study. (NCT06271369)Novartis Pharmaceuticals2022-08-11
Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V (NCT05268289)Novartis Pharmaceuticals2022-08-10
Phase II of Neoadjuvant and Adjuvant Capmatinib in NSCLC (NCT04926831)Novartis Pharmaceuticals2022-08-10
Observational Retrospective Study to Assess the Use of Ribociclib in Patients With HR+, HER2- Metastatic Breast Cancer Treated With Chemotherapy (NCT06619704)Novartis Pharmaceuticals2022-08-10
Study to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine Treatment (NCT05631795)Novartis Pharmaceuticals2022-08-09
A Study of Patient Characteristics and Treatment Patterns in Real-world Melanoma Patients Treated With Dabrafenib and Trametinib or Encorafenib and Binimetinib in Japan (NCT07649252)Novartis Pharmaceuticals2022-08-01
Two-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome (NCT05350072)Novartis Pharmaceuticals2022-07-28
Secondary Use of PARALLEL-HF Data (NCT07527767)Novartis Pharmaceuticals2022-07-27
Biopsy Based Study to Understand Mechanism of Action of Ianalumab in Salivary Glands and Explore Relationships With Clinical Assessments. (NCT05124925)Novartis Pharmaceuticals2022-07-27
Exploring the Profiles of RMS Patients on Ofatumumab or Ocrelizumab in a Real-World Setting in the Gulf (NCT05266469)Novartis Pharmaceuticals2022-07-26
Study of Efficacy and Safety of Ofatumumab in Relapsing Multiple Sclerosis (RMS) Patients in China (NCT05199571)Novartis Pharmaceuticals2022-07-22
Safety, Efficacy and Tolerability of Ianalumab Versus Placebo, Combination With SoC Therapy, in Participants With Active Lupus Nephritis (NCT05126277)Novartis Pharmaceuticals2022-07-14
A Study of [177Lu]Lu-DOTA-TATE in Newly Diagnosed ES-SCLC Patients in Combination With Carboplatin, Etoposide and Atezolizumab (NCT05142696)Novartis Pharmaceuticals2022-07-13
Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events (NCT05360446)Novartis Pharmaceuticals2022-07-08
Roll-over Study to Allow Continued Access to Ribociclib (NCT05161195)Novartis Pharmaceuticals2022-07-07
A Study of Real-world Treatment and Burden of Chronic Myeloid Leukemia Patients in Japan (NCT07150793)Novartis Pharmaceuticals2022-07-05
A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas (NCT05415072)Novartis Pharmaceuticals2022-07-04
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