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Novartis Pharmaceuticals

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RecordFirmDate
Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients With Primary IgAN (NCT06994845)Novartis Pharmaceuticals2025-11-27
A Phase I Study of JSB462 (Luxdegalutamide) in Japanese Patients With Metastatic Prostate Cancer (NCT07174063)Novartis Pharmaceuticals2025-11-26
Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With Dyslipidemia (NCT07034690)Novartis Pharmaceuticals2025-11-26
Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors (NCT07261631)Novartis Pharmaceuticals2025-11-24
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease (NCT07235059)Novartis Pharmaceuticals2025-11-20
A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis (NCT07225504)Novartis Pharmaceuticals2025-11-11
Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis (NCT07220577)Novartis Pharmaceuticals2025-11-10
A Phase II Trial to Evaluate the Clinical Efficacy, Safety and Tolerability of MAS825 in Pediatric and Adult Participants With Still's Disease (NCT07203001)Novartis Pharmaceuticals2025-11-03
Study to Assess the Pharmacokinetics, Safety, and Tolerability of Iptacopan in Pediatric PNH Patients (NCT06934967)Novartis Pharmaceuticals2025-10-28
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation (NCT07217067)Novartis Pharmaceuticals2025-10-28
Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors (NCT07006727)Novartis Pharmaceuticals2025-10-16
An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01) (NCT07206056)Novartis Pharmaceuticals2025-10-15
EPIK-P4: A Phase II Single-arm Study to Assess the Efficacy, Safety and Pharmacokinetics of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum (PROS) (NCT06997588)Novartis Pharmaceuticals2025-10-09
Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes (NCT07102628)Novartis Pharmaceuticals2025-10-03
A First in Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of EDK060 in Adults With CMT1A. (NCT07140614)Novartis Pharmaceuticals2025-09-30
Evaluation of 1-Year Clinical Outcomes With Early Inclisiran Initiation in Post-MI Patients (NCT07142265)Novartis Pharmaceuticals2025-09-30
Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA). (NCT06751238)Novartis Pharmaceuticals2025-09-24
Fabhalta Capsules Specified Drug-use Survey (NCT07156149)Novartis Pharmaceuticals2025-09-17
An Open-label Study of Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI Versus AAA617 in PSMA Positive First-line mCRPC (NCT06894511)Novartis Pharmaceuticals2025-09-11
RWE Non-Interventional Prospective Study of Ribociclib Effectiveness and Safety in Patients With HR+/HER2- Early Breast Cancer in Saudi Arabia (NCT06797531)Novartis Pharmaceuticals2025-08-27
Leqvio rPMS (Regulatory Post-Marketing Surveillance in Korea) (NCT06770543)Novartis Pharmaceuticals2025-08-13
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease (NCT07094516)Novartis Pharmaceuticals2025-08-07
Observational Study on Lutetium (177Lu) Vipivotide Tetraxetan to Treat Metastatic Castration Resistant Prostate Cancer (NCT07093801)Novartis Pharmaceuticals2025-07-30
NIS PDC the Efficacy and Safety of Iptacopan in Adults in Routine Clinical Practice (NCT07036718)Novartis Pharmaceuticals2025-07-29
Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy. (NCT06858319)Novartis Pharmaceuticals2025-07-28
A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Severe Renal Impairment Compared to Matched Healthy Participants. (NCT07032272)Novartis Pharmaceuticals2025-07-23
A Study to Evaluate Efficacy of Remibrutinib Compared to Dupilumab at Early Timepoints in Adults With Chronic Spontaneous Urticaria Inadequately Controlled by Second Generation H1-antihistamines (NCT06868212)Novartis Pharmaceuticals2025-07-11
A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer (mCRPC) (NCT07047118)Novartis Pharmaceuticals2025-07-03
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis. (NCT06846281)Novartis Pharmaceuticals2025-06-23
A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease (NCT07048197)Novartis Pharmaceuticals2025-06-20
Inclisiran Effectiveness in China: a Pragmatic Randomized Trial (NCT06941792)Novartis Pharmaceuticals2025-06-17
Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study (NCT06958315)Novartis Pharmaceuticals2025-06-16
An Ascending Dose Study of PIT565 in Participants With Rheumatoid Arthritis (NCT07029555)Novartis Pharmaceuticals2025-06-12
A Multi-center, Ambispective Cohort Study to Evaluate the Impact of Iptacopan for Adult Patients With PNH in China (NCT06931691)Novartis Pharmaceuticals2025-06-10
A Real-world Study of Disease-modifying Therapy Treatment Outcomes in Patients With Spinal Muscular Atrophy (NCT07403214)Novartis Pharmaceuticals2025-06-04
DFT383 in Pediatric Participants With Nephropathic Cystinosis (NCT06910813)Novartis Pharmaceuticals2025-06-02
Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients With Grade 1 and Grade 2 Advanced GEP-NET (NCT06784752)Novartis Pharmaceuticals2025-05-30
Study of Remibrutinib (LOU064) Efficacy and Safety and Exploration of Its Mechanism of Action in Participants With Chronic Urticaria (NCT06865651)Novartis Pharmaceuticals2025-05-22
Phase III Extension Study of Efficacy and Safety of Ianalumab With or Without Study Treatment Withdrawal in Participants With Lupus Nephritis (SIRIUS-LN Extension) (NCT06711887)Novartis Pharmaceuticals2025-05-19
Pelacarsen Roll-over Extension Program (NCT06875973)Novartis Pharmaceuticals2025-05-19
Platform Study to Evaluate the Efficacy and Safety of Investigational Compound(s) in Patients With Moderate to Severe Atopic Dermatitis (NCT06947993)Novartis Pharmaceuticals2025-05-16
Prospective Observational Study to Evaluate Secukinumab Treatment Effectiveness in Pediatric Patients With Active Juvenile Enthesitis-related or Psoriatic Arthritis (NCT06431750)Novartis Pharmaceuticals2025-04-30
Lp(a) Lowering Study of Pelacarsen (TQJ230) With Background Inclisiran in Participants With Elevated Lp(a) and Established ASCVD (NCT06813911)Novartis Pharmaceuticals2025-04-30
A Study of Efficacy, Safety, Tolerability of LXE408 in Participants With Chronic Chagas Disease. (NCT06632600)Novartis Pharmaceuticals2025-04-28
Post Marketing Study on Pluvicto in Korea (NCT06514521)Novartis Pharmaceuticals2025-04-18
Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia (NCT06858332)Novartis Pharmaceuticals2025-04-15
Home Reported Outcomes in C3G Study (NCT07029542)Novartis Pharmaceuticals2025-04-07
Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors (NCT06726148)Novartis Pharmaceuticals2025-04-03
Real-world Study on Secukinumab Effectiveness in Biologic-naïve Ankylosing Spondylitis (AS) Patients in Korea. (NCT06905288)Novartis Pharmaceuticals2025-04-02
Post-authorization Safety Study of Iptacopan in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Using Data From the IPIG PNH Registry (NCT06903234)Novartis Pharmaceuticals2025-03-31
Ilaris NIS in Korea (NCT06838143)Novartis Pharmaceuticals2025-03-29
A Study to Identify an Optimal Dose of QCZ484 in Mild to Moderate Hypertensive Patients (NCT06857955)Novartis Pharmaceuticals2025-03-26
RWE,NIS,Prospective Study for the Effectiveness, Tolerability and Adherence of Asciminib in Saudi Arabia. (ASC4REAL) (NCT06684964)Novartis Pharmaceuticals2025-03-24
A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (NCT06840392)Novartis Pharmaceuticals2025-03-20
Pharmacokinetics Study of TNO155 in Participants With Mild, Moderate, or Severe Renal Impairment Compared to Matched Healthy Participants (NCT05541159)Novartis Pharmaceuticals2025-03-19
Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA (NCT06868290)Novartis Pharmaceuticals2025-03-13
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of a New Maintenance Dosing Regimen of Ofatumumab (NCT06869785)Novartis Pharmaceuticals2025-03-13
Long-term Follow up Local Registry Study of Kymriah in South Korea (NCT06785818)Novartis Pharmaceuticals2025-03-12
Assessing Short-term Treatment Satisfaction and Quality of Life in Patients With Hidradenitis Suppurativa Initiated on Secukinumab. (NCT06785675)Novartis Pharmaceuticals2025-03-10
A Study of Treatment Patterns and Annualized Relapse Rate in Multiple Sclerosis Patients Who Escalate Versus Continue Disease-Modifying Therapies Following Relapse (NCT07743281)Novartis Pharmaceuticals2025-03-10
Short-term Treatment Satisfaction in Hidradenitis Suppurativa Patients Initiated on Cosentyx in Routine Clinical Practice in Saudi Arabia (NCT06785779)Novartis Pharmaceuticals2025-03-10
Pharmacokinetics of TNO155 in Participants With Mild, Moderate, or Severe Hepatic Impairment Compared to Matched Healthy Participants (NCT05490030)Novartis Pharmaceuticals2025-03-06
A Mobile App-Based Study to Evaluate Disease Burden and Treatment Patterns in Immunoglobulin A Nephropathy (IgAN) in the US (NCT06952426)Novartis Pharmaceuticals2025-03-04
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia (NCT06597006)Novartis Pharmaceuticals2025-02-28
Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy (NCT06780670)Novartis Pharmaceuticals2025-02-27
A Real-World Study of Treatment Patterns, Tolerability and Effectiveness of CDK4/6 Inhibition in HR+, HER2-negative Metastatic Breast Cancer Patients (NCT07760714)Novartis Pharmaceuticals2025-02-26
An Open-label Study to Assess the Safety, Efficacy, and Cellular Kinetics of YTB323 in Relapsing Multiple Sclerosis (NCT06617793)Novartis Pharmaceuticals2025-02-24
Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN (NCT06797518)Novartis Pharmaceuticals2025-02-21
A Non-interventional Study for Kisqali (Ribociclib) in Combination With an Aromatase Inhibitor for Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer at High Risk of Recurrence (NCT06830720)Novartis Pharmaceuticals2025-02-20
Open-label Study of Asciminib for CML-CP or CML-AP Patients With T315I Mutation Who Are Resistant, Intolerant or Ineligible to Ponatinib. (NCT06514534)Novartis Pharmaceuticals2025-02-18
LATAM LOWERS LDL-C (NCT06501443)Novartis Pharmaceuticals2025-02-11
A Study to Investigate the Efficacy, Safety and Tolerability of Remibrutinib Versus Placebo in Adult Patients With Generalized Myasthenia Gravis (NCT06744920)Novartis Pharmaceuticals2025-02-07
A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE 1) (NCT06799000)Novartis Pharmaceuticals2025-01-31
Modifying PEST for Psoriatic Arthritis Screening (NCT06382051)Novartis Pharmaceuticals2025-01-23
A Study to Assess the Real-World Effectiveness of Inclisiran and PCSK9 mAbs in Chinese Hypercholesterolemia Adult Patients (NCT07409636)Novartis Pharmaceuticals2025-01-23
A Study of Sabatolimab and Magrolimab-based Treatment in AML or Higher Risk MDS Participants (NCT05367401)Novartis Pharmaceuticals2024-12-20
Entresto Tablets and Granules for Pediatric Specified Drug-use Survey (Pediatric Chronic Heart Failure) (NCT06659393)Novartis Pharmaceuticals2024-12-19
Phase 2 Study of Rapcabtagene Autoleucel in Myositis (NCT06665256)Novartis Pharmaceuticals2024-12-17
Open-label, Multi-center, Phase I/II Study to Assess Safety, Disease Progression and Cellular Kinetics Following YTB323 Administration in Participants With Non-active Progressive Multiple Sclerosis (PMS) (NCT06675864)Novartis Pharmaceuticals2024-12-12
Post Marketing Study to Evaluate the Safety and Effectiveness of Brolucizumab in Patients With Diabetic Macular Edema. (NCT05959304)Novartis Pharmaceuticals2024-12-11
Kesimpta (Ofatumumab) in Greek Multiple Sclerosis Patients - an Observational Study (NCT06486779)Novartis Pharmaceuticals2024-12-10
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia (NCT06597019)Novartis Pharmaceuticals2024-12-09
Clinical Study of Asciminib in Previously Treated Indian Patients With Ph+ CML-CP Without T315I Mutation and in Patients With Ph+ CML-CP With T315I Mutation (NCT06427811)Novartis Pharmaceuticals2024-11-28
ELIOS - Investigational Biomarkers to Track Disease Modification in Active RRMS (NCT06733922)Novartis Pharmaceuticals2024-11-27
Pharmacokinetics Study of Ianalumab in Chinese Participants With Autoimmune Diseases (NCT06411639)Novartis Pharmaceuticals2024-11-25
Multiple Sclerosis Patient Experience on Kesimpta and Ocrevus Subcutaneous Formulation (NCT06668324)Novartis Pharmaceuticals2024-11-15
A Clinical Study to Evaluate the Safety and Effectiveness of Inclisiran Sodium in Indian Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia (NCT06386419)Novartis Pharmaceuticals2024-11-12
A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study (NCT06531499)Novartis Pharmaceuticals2024-11-11
A Study of Dosing Patterns and Costs in Patients With Spinal Muscular Atrophy Receiving Disease Modifying Therapies (NCT07378943)Novartis Pharmaceuticals2024-11-06
A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis (NCT06551519)Novartis Pharmaceuticals2024-10-28
A Real-world Study Comparing the Effectiveness of Ofatumumab and Ocrelizumab Treatment in Multiple Sclerosis Patients (NCT07566988)Novartis Pharmaceuticals2024-10-25
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B) (NCT06649110)Novartis Pharmaceuticals2024-10-24
A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) (NCT06439082)Novartis Pharmaceuticals2024-10-24
A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS) (NCT06643481)Novartis Pharmaceuticals2024-10-17
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers (NCT06562192)Novartis Pharmaceuticals2024-10-15
A Prospective Non-interventional Study to Evaluate Clinical Outcomes of Ribociclib Combined With Endocrine Therapy in Elderly Patients With HR+HER2 - Advanced Breast Cancer in Routine Clinical Practice in Russian Federation (NCT06625333)Novartis Pharmaceuticals2024-10-11
A Clinical Study to Evaluate Ianalumab in Participants With Diffuse Cutaneous Systemic Sclerosis (NCT06470048)Novartis Pharmaceuticals2024-10-09
An Ascending Dose Study of PIT565 in Participants With Systemic Lupus Erythematosus (SLE). (NCT06335979)Novartis Pharmaceuticals2024-10-08
Specified Drug-use Surveillance of Fabhalta Capsules (NCT06606314)Novartis Pharmaceuticals2024-09-18
A Real-world Study of Characteristics, Treatment Patterns, and Clinical Outcomes Among Lutetium-177 Vipivotide Tetraxetan Treated Patients (NCT07477756)Novartis Pharmaceuticals2024-09-04
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