| Study to Evaluate the Efficacy and Safety of Different Doses of Graminidin With Anesthetic, a Metered Dose Topical Spray, in the Treatment of Acute Infectious and Inflammatory Pharyngeal Diseases Compared With Drug Septolete Total, Lozenges (NCT06843018) | Valenta Pharm JSC | 2024-11-14 |
| An Adaptive Design Study of MTX228 (NCT06474598) | University of Alberta | 2024-11-14 |
| Efficacy and Safety of Platelet-rich Plasma, Metformin and Cryotherapy in Treatment of Non-genital Warts (NCT06691542) | Assiut University | 2024-11-14 |
| Irinotecan Liposomes +5-FU/LV Versus Capecitabine in Patients of Recurrence After Resection of Resectable BTC (NCT06699459) | Sir Run Run Shaw Hospital | 2024-11-14 |
| Efficacy, Safety, and Pharmacokinetics of LP-005 Injection in PNH Patients. (NCT07212426) | Longbio Pharma | 2024-11-14 |
| Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy (NCT06477692) | University of Texas Southwestern Medical Center | 2024-11-14 |
| The Clinical Trial of TQB2102 for Injection Against Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (NCT06452706) | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 2024-11-14 |
| A Study of Medical Cannabis Aerosol Via the Fixed-dose Syqe Inhaler as an Add-on Treatment of Diabetic Peripheral Neuropathic Pain (DPNP) (NCT06490445) | Syqe Medical | 2024-11-14 |
| Trifluridine/tipiracil (TAS-102), Bevacizumab, and Camrelizumab As Third-line or Later-line Therapy of Gastric Cancer (NCT06711471) | LIN YANG | 2024-11-14 |
| Clinical Study of TQA3605 Tablets Combined With Nucleoside (Acid) Analogs (NAs) Drugs Compared With NAs Drugs in the Treatment of Chronic Hepatitis B Virus (HBV) Infection (NCT06644417) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2024-11-14 |
| A Study to Investigate the Safety and Efficacy of TMP-301 Compared to Placebo in Adult Patients With Alcohol Use Disorder (NCT06648655) | Tempero Bio, Inc. | 2024-11-14 |
| Study of Cemiplimab Alone or in Combination With Fianlimab and/or Other Experimental Agents in Adult Participants With Peri-operative Stage III/IV Cutaneous Squamous Cell Carcinoma (CSCC) (NCT06384820) | Regeneron Pharmaceuticals | 2024-11-14 |
| A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE) (NCT06422923) | Neurona Therapeutics | 2024-11-14 |
| Avelumab and M1774 in ARID1A-mutated Endometrial Cancer (NCT06518564) | Panagiotis Konstantinopoulos, MD, PhD | 2024-11-14 |
| Nanobody-Based CD19/CD22 Tandem Dual CAR-T Therapy for R/R B-ALL (NCT06880913) | Peking University People's Hospital | 2024-11-14 |
| A Study to Investigate Sonrotoclax Combined With Zanubrutinib Versus Zanubrutinib Alone in Participants With Previously Untreated Chronic Lymphocytic Leukemia (NCT06637501) | BeOne Medicines | 2024-11-14 |
| Robotic Gastrectomy for Locally Advanced Gastric Cancer After Neoadjuvant Therapy (NCT06895447) | The First Affiliated Hospital with Nanjing Medical University | 2024-11-14 |
| A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (PAH) (MK-7962-024) (NCT06664801) | Merck Sharp & Dohme LLC | 2024-11-14 |
| A Study to Investigate Weight Management With LY3549492 Compared With Placebo in Adult Participants With Obesity or Overweight (NCT06683508) | Eli Lilly and Company | 2024-11-13 |
| A Study on the Immune Response and Safety of a Multicomponent Shigella Vaccine in Preventing Shigellosis in Infants (NCT06663436) | GlaxoSmithKline | 2024-11-13 |
| A Phase 2 Clinical Study of ABSK061 and ABSK043 (NCT06632262) | Abbisko Therapeutics Co, Ltd | 2024-11-13 |
| Safety and Efficacy of SYHA1813 Single Agent or in Combination With Different Regimens in Unresectable Locally Advanced or Metastatic Solid Tumors. (NCT06682611) | Shanghai Runshi Pharmaceutical Technology Co., Ltd | 2024-11-13 |
| Metformin and Vascular Function in Prediabetes (NCT06526494) | Diana Jalal | 2024-11-13 |
| IMRT Combined With Lobaplatin-based CCRT in Nasopharyngeal Carcinoma (NCT06688175) | The First Affiliated Hospital of Xiamen University | 2024-11-13 |
| A Study of FC084CSA in Combination of Tislelizumab in Patients With Advanced Malignant Solid Tumors (NCT06499350) | FindCure Biosciences (ZhongShan) Co., Ltd. | 2024-11-13 |
| Orelabrutinib Combined With Zuberitamab in the Initial Treatment of MZL (NCT06985472) | Li Zhiming | 2024-11-13 |
| Oral Acetaminophen for Post-Op Pain Management in Bariatric Surgery Patients (NCT06658574) | Rutgers, The State University of New Jersey | 2024-11-13 |
| Antiemetic Fosaprepitant To Remedy Nausea and Vomiting (NCT06382012) | Montefiore Medical Center | 2024-11-13 |
| Study of Natriuretic Peptide Receptor 1 (NPR1) Antagonist in Adult Patients With Postural Orthostatic Tachycardia Syndrome (POTS) (NCT06593600) | Regeneron Pharmaceuticals | 2024-11-13 |
| Trilaciclib Combing Chemotherapy in the Neoadjuvant Treatment of Osteosarcoma (NCT06714383) | Peking University People's Hospital | 2024-11-13 |
| A Phase II Study of Zuberitamab Injection in Patients With Primary Membranous Nephropathy (NCT06642909) | BioRay Pharmaceutical Co., Ltd. | 2024-11-13 |
| Polarized Dendritic Cell (aDC1) Based Treatment, Interferon Alpha-2, Rintatolimod, and Celecoxib for the Treatment of HLA-A2+ Refractory Melanoma (NCT04093323) | Roswell Park Cancer Institute | 2024-11-13 |
| Safety and Immunogenicity of Recombinant RSV Vaccine (CHO Cell) in Healthy Subjects Aged 18 Years and Above (NCT06642558) | MAXVAX Biotechnology Limited Liability Company | 2024-11-13 |
| A Phase 1/2 Study of GEN1286 in Patients With Advanced Solid Tumors (NCT06685068) | Genmab | 2024-11-13 |
| A Human Challenge Study to Assess Protection of a Shigella Tetravalent Bioconjugate Vaccine (NCT06615375) | LimmaTech Biologics AG | 2024-11-12 |
| LDGraft in Single Level Anterior Lumbar Interbody Fusion (ALIF) (NCT06462729) | Locate Bio Pty Ltd | 2024-11-12 |
| Azithromycin for Meningococcal Carriage (NCT06618534) | Emory University | 2024-11-12 |
| Clinical Study of Second-line Treatment in Advanced Colorectal Cancer With Chemotherapy With Bevacizumab or Cetuximab (NCT06540326) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2024-11-12 |
| Evaluating a New Peptide Therapy for Retinal Diseases: AMD, Diabetic Retinopathy, and Dystrophies (NCT06787482) | Ace Cells Lab Limited | 2024-11-12 |
| FMRI of Patients Receiving IV Ketamine for Treatment Resistant Bipolar Depression (NCT06620042) | Brian Barnett | 2024-11-12 |
| A 2-part Study Consisting of a Multiple Ascending Dose Safety Study in Participants With Macular Edema Following Branch Retinal Vein Occlusion and a Dose-finding Safety and Preliminary Efficacy Study in Participants With Either Diabetic Macular Edema or Neovascular Age-related Macular Degeneration (NCT06664502) | EyeBiotech Ltd. | 2024-11-12 |
| Toripalimab Combined With Capecitabine as Postoperative Adjuvant Therapy for Patients With Resectable Advanced Extrahepatic Biliary Tract Cancer (NCT06717464) | Tianjin Medical University Cancer Institute and Hospital | 2024-11-12 |
| A Dose Escalation Study of IG3018 in Subjects With Hyperuricemia With or Without Chronic Kidney Disease (NCT06310967) | Intelligem Therapeutics Australia Pty Ltd. | 2024-11-12 |
| Phase I/II Study to a Assess the GBS-06 Vaccine Manufactured by Inventprise, Inc., in Healthy, Non-Pregnant, Adult Women of Childbearing Age. (NCT06611371) | Inventprise Inc. | 2024-11-12 |
| Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor (NCT07433283) | Sichuan Enray Pharmaceutical Sciences Company | 2024-11-12 |
| An Exploratory, Multi-cohort Phase II Study of Combination Therapy With AK104 and AK112 for Recurrent Ovarian Cancer (NCT06560112) | Akeso | 2024-11-12 |
| Prophylactic Intervention for Relapse Prevention Post-Allogeneic Transplantation in Very High-Risk MDS Patients Based on IPSS-M Stratification (NCT06612944) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2024-11-12 |
| Sintilimab Plus Rituximab Followed by R-CHOP Regimen in Untreated PMBL (NCT06742502) | Sun Yat-sen University | 2024-11-12 |
| Toripalimab Combined With Gemcitabine and Cisplatin (GemCis) as Preoperative Neoadjuvant Therapy for Resectable Intrahepatic Cholangiocarcinoma (NCT06721286) | Tianjin Medical University Cancer Institute and Hospital | 2024-11-12 |
| Study of CM313 (SC) Injection in Subjects With Primary Immune Thrombocytopenia (ITP) (NCT06594146) | Keymed Biosciences Co.Ltd | 2024-11-11 |
| The Tatelo Plus Study (NCT06508749) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-11-11 |
| A Study to Learn About Flu and COVID-19 Vaccine Responses in Healthy People (NCT06683352) | BioNTech SE | 2024-11-11 |
| A Study of Sequential Therapy With Daplusiran/Tomligisiran (DAP/TOM) Followed by Bepirovirsen in Participants Living With Chronic Hepatitis B (CHB) (NCT06537414) | GlaxoSmithKline | 2024-11-11 |
| A Multi-Arm, Platform Trial For Relapsed Neuroblastoma (NCT07334301) | University of Birmingham | 2024-11-11 |
| Risk Adapted Spinal Cord/Cauda Constraint Relaxation for High-risk Patients With Metastatic Epidural Spinal Cord Compression Undergoing Spine Stereotactic Radiosurgery (NCT06204315) | M.D. Anderson Cancer Center | 2024-11-11 |
| A Study to Assess the Efficacy and Safety of Efgartigimod PH20 SC in Adults With Systemic Sclerosis (NCT06655155) | argenx | 2024-11-11 |
| Daridorexant to Prevent Delirium After Heart Surgery (NCT06630390) | University of Rochester | 2024-11-11 |
| Study of a Human Metapneumovirus/Respiratory Syncytial Virus mRNA Vaccine Candidate Encapsulated in a Lipid Nanoparticle-based Formulation in Adults Aged 60 Years and Older (NCT06686654) | Sanofi Pasteur, a Sanofi Company | 2024-11-11 |
| Efficacy of Endothelin Receptor Antagonism in Coronary Artery Spasm (NCT06432452) | Radboud University Medical Center | 2024-11-11 |
| Namodenoson Treatment of Advanced Pancreatic Cancer (NCT06387342) | Can-Fite BioPharma | 2024-11-10 |
| Lusutrombopag Combined With Recombinant Human Thrombopoietin for the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Destined to Undergo Elective Invasive Surgery (NCT06673498) | Anhui Provincial Hospital | 2024-11-10 |
| Ruxolitinib as First Line Treatment in Primary Haemophagocytic Lymphohistiocytosis (R-HLH) (NCT05762640) | Assistance Publique - Hôpitaux de Paris | 2024-11-10 |
| Glofitamab Bridging ASCT for Patients With Relapsed or Refractory DLBCL (NCT06682130) | The First Affiliated Hospital of Soochow University | 2024-11-10 |
| The Application of CAR-T Cell Therapy in Relapsed and Refractory Malignant Hematologic Tumors (NCT06911710) | Tianjin Medical University General Hospital | 2024-11-09 |
| A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of AUR 109 in Patients With Colorectal, Ovarian, and Renal Cancers (NCT06760702) | Aurigene Discovery Technologies Limited | 2024-11-09 |
| Study of Posaconazole Prophylaxis in Patients Receiving Hematopoietic Stem Cell Allograft (Allo-HSC) at High Risk of Invasive Fungal Infection (IFI) (NCT06541067) | Nantes University Hospital | 2024-11-08 |
| Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial (NCT06639074) | Mayo Clinic | 2024-11-08 |
| New Adjuvant Vaccine in Glioblastoma, a Phase 1/2a Study (NCT06622434) | Assistance Publique - Hôpitaux de Paris | 2024-11-08 |
| Synergistic Effects of PD-1 Antibody and Chemotherapy/Targeted Therapy Followed by Surgery-centric Local Treatment in Patients With Limited-metastatic Gastric Cancer (NCT06468280) | Shanghai Zhongshan Hospital | 2024-11-08 |
| Baricitinib in the Treatment of Intestinal Behçet's Syndrome (NCT06849908) | Peking Union Medical College Hospital | 2024-11-08 |
| A Study to Assess the Safety, Tolerability, and Pharmacology of Darifenacin in Patients With ALS (NCT06249867) | Oliver Blanchard | 2024-11-08 |
| Fluorescence Imaging of Risankizumab-800CW in Inflammatory Bowel Disease (NCT06606808) | University Medical Center Groningen | 2024-11-08 |
| Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) (NCT06648096) | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 2024-11-08 |
| Phase 2a Trial to Investigate the Efficacy of LIB-01 in Treatment of Erectile Dysfunction (NCT06703840) | Dicot AB | 2024-11-08 |
| A Study of RNK08954 in Subjects With Advanced Solid Tumors With KRAS ((Kirsten Rat Sarcoma) G12D Mutation (NCT06667544) | Ranok Therapeutics (Hangzhou) Co., Ltd. | 2024-11-08 |
| Camrelizumab and Chemotherapy With or Without Anlotinib as First-line Treatment for Advanced Gallbladder Cancer and Extrahepatic Cholangiocarcinoma (NCT06901622) | The First Affiliated Hospital of Zhengzhou University | 2024-11-08 |
| Efficacy and Safety of GNT0003 Following Imlifidase Pre-treatment in Severe Crigler-Najjar Syndrome (NCT06518005) | Genethon | 2024-11-08 |
| Anti-Lag-3 (Relatlimab) and Anti-PD-1 Blockade (Nivolumab) Versus Standard of Care (Lomustine) for the Treatment of Patients With Recurrent Glioblastoma (NCT06325683) | National Cancer Institute (NCI) | 2024-11-08 |
| The Effect of Non-invasive Auricular Acupoint Stimulation on Slow Transmission Constipation (NCT06680882) | The Second Affiliated Hospital of Anhui University of Traditional Chinese Medicine | 2024-11-07 |
| A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers (NCT05893888) | Privo Technologies | 2024-11-07 |
| A Study of Maridebart Cafraglutide in Adult Participants With Type 2 Diabetes Mellitus (T2DM) (NCT06660173) | Amgen | 2024-11-07 |
| Neoadjuvant Befotertinib Combined Bevacizumab or Platinum-based Double Chemotherapy for Resectable Locally-advanced EGFR Mutation-positive Non-Small Cell Lung Cancer (NCT06755684) | Peng Zhang | 2024-11-07 |
| Effectiveness of Cryotherapy on Endodontic Pain (NCT06785753) | Armed Forces Institute of Dentistry, Pakistan | 2024-11-07 |
| A Study to Evaluate ALN-6400 in Healthy Volunteers and Patients With Hereditary Hemorrhagic Telangiectasia (HHT) (NCT06659640) | Alnylam Pharmaceuticals | 2024-11-07 |
| Study of Lunsekimig (SAR443765) Compared With Placebo in Adults With High-risk Asthma (NCT06676319) | Sanofi | 2024-11-07 |
| Discontinuation of Hypomethylating Agent and Venetoclax in Patients With AML MRD (NCT06511882) | H. Lee Moffitt Cancer Center and Research Institute | 2024-11-07 |
| The Unique and Combined Effects of Prenatal and Early Childhood Programming on Child Maltreatment: Examining Mechanisms of Change (NCT06732310) | University of Notre Dame | 2024-11-07 |
| Identification of Nerves Using Fluorescein Sodium (NCT06054178) | Stanford University | 2024-11-07 |
| A Study of SI-B001+SI-B003 Combined With Platinum-based Chemotherapy as First-line Treatment in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (NCT06668961) | Sichuan Baili Pharmaceutical Co., Ltd. | 2024-11-07 |
| Pirtobrutinib (LOXO-305) and Venetoclax for the Treatment of Patients With CLL or SLL Resistant to Covalent BTKi (NCT06466122) | Kerry Rogers | 2024-11-07 |
| Gene Therapy for Crigler Najjar Syndrome Type I (AlphaCN) (NCT06641154) | Federal State Budget Institution Research Center for Obstetrics, Gynecology and Perinatology Ministry of Healthcare | 2024-11-06 |
| A Study of Melphalan With or Without Siltuximab in People With Multiple Myeloma Having an Autologous Stem Cell Transplant (NCT06679829) | Memorial Sloan Kettering Cancer Center | 2024-11-06 |
| A Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 Lymphopenia (NCT05600920) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-11-06 |
| Nab-P+Cb+PD1 Inhibitors as Neoadjuvant Therapy for Early TNBC (NCT06817525) | Henan Cancer Hospital | 2024-11-06 |
| Individualizing Corticosteroid Use in Pneumonia (NCT05334316) | Mayo Clinic | 2024-11-06 |
| Induction Chemo+Immunotherapy in Resectable Epithelioid and Biphasic Pleural Mesothelioma (CHIMERA Study) (NCT06155279) | Istituto Oncologico Veneto IRCCS | 2024-11-06 |
| A Multicenter Study on the Treatment of MDS/MPN Overlap Syndrome With AZA or Rux Combined With Selinexor (NCT06664970) | Peking Union Medical College Hospital | 2024-11-06 |
| RLC Followed by CR-CHOP in Elderly Patients with Newly-diagnosed DEL (NCT06674096) | Zhejiang Cancer Hospital | 2024-11-06 |
| A Study to Evaluate Physiologic Dentin Regeneration and Safety of KH001 in the Administration of Erupted Wisdom Tooth With Dentin Caries (NCT06580678) | Byoung-Moo Seo | 2024-11-06 |
| The University of Miami Adapt (UAdapt) Trial (NCT06111313) | University of Miami | 2024-11-06 |