| CD70-targeted immunoPET Imaging of Malignant Cancers (NCT06852638) | RenJi Hospital | 2024-12-23 |
| Dupilumab Versus Topical Corticosteroid Effectiveness - Comparison in the Treatment of Stenotic EoE (NCT06705387) | University of Colorado, Denver | 2024-12-23 |
| Safety and Preliminary Efficacy of VG801 in Patients With ABCA4 Mutation-associated Retinal Dystrophy (Stargardt Disease) (NCT07002398) | VeonGen Therapeutics GmbH | 2024-12-23 |
| Multicenter, Phase II Randomized Controlled Study of Adebrelimab Combined With Chemotherapy and Concurrent Low-Dose Radiotherapy (LDRT) for the Treatment of Extensive-Stage Small Cell Lung Cancer (SCLC) (NCT06610734) | Sichuan University | 2024-12-23 |
| Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease (NCT06635902) | Suvankar Majumdar | 2024-12-22 |
| Hydroxychloroquine Sulfate Tablets for Radiation-induced Oral Mucositis (NCT06939582) | Xingchen Peng | 2024-12-22 |
| Pembrolizumab in High-risk Thyroid Cancer (NCT05852223) | Istituti Clinici Scientifici Maugeri SpA | 2024-12-20 |
| A Phase 2, Baseline-Controlled Study Evaluating the Safety and Efficacy of PTX-022 (Sirolimus) Topical Gel 3.9% in the Treatment of Cutaneous Venous Malformations (NCT06653842) | Palvella Therapeutics, Inc. | 2024-12-20 |
| Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance (NCT06483100) | Washington University School of Medicine | 2024-12-20 |
| A Phase IIb Study of 610 in Participants With Severe Eosinophilic Asthma (NCT06680947) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2024-12-20 |
| Belzutifan in Recurrent Clear Cell Carcinoma of Gynecologic Origin (NCT06677190) | Dana-Farber Cancer Institute | 2024-12-20 |
| Radiotherapy Followed by Tiselizumab Combined With RCHOP in Previously Untreated Bulky Follicular Lymphoma (NCT06704555) | Tianjin Medical University Cancer Institute and Hospital | 2024-12-20 |
| A Study of Sabatolimab and Magrolimab-based Treatment in AML or Higher Risk MDS Participants (NCT05367401) | Novartis Pharmaceuticals | 2024-12-20 |
| The Optimal Radioimmunotherapy Combinations for Advanced TNBC (NCT06735131) | Sun Yat-sen University | 2024-12-20 |
| A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027) (NCT06637423) | Merck Sharp & Dohme LLC | 2024-12-20 |
| Chidamide Combined With Angiogenesis Inhibitors and Fulvestrant for Advanced HR-positive, HER2-negative Breast Cancer (NCT06750848) | Jundong Wu | 2024-12-20 |
| Administration of Intranasal Midazolam for Anxiety in Palliative Care (NCT06330584) | Insel Gruppe AG, University Hospital Bern | 2024-12-20 |
| Proof-of-concept Study to Evaluate the Safety and Efficacy of Tryptophan in Patients with BPH. (NCT05401032) | Clinical Academic Center (2CA-Braga) | 2024-12-20 |
| Ivonescimab Combined with Chemotherapy As First-line Treatment of Relapsed or Metastatic Thymic Cancer: a Prospective, Single Arm, Phase II Trial (NCT06750952) | Sun Yat-sen University | 2024-12-20 |
| Blockade of the Renin-angiotensin-aldosterone System in Patients With ARVD (NCT03593317) | Hospices Civils de Lyon | 2024-12-20 |
| A Study of GC101 TIL in Advanced Melanoma (NCT06703398) | Shanghai Juncell Therapeutics | 2024-12-20 |
| Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WM (NCT06561347) | Massachusetts General Hospital | 2024-12-20 |
| Study of Disitamab Vedotin With Toripalimab Verus Disitamab Vedotin in Hormone Receptor Positive, HER2-low Locally Advanced or Metastatic Breast Cancer (NCT06105008) | RemeGen Co., Ltd. | 2024-12-20 |
| A Clinical Trials of Adsorbed Cell-free DPT Vaccine (Five-component) (NCT06708286) | CanSino Biologics Inc. | 2024-12-20 |
| A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a New Formulation of Cabotegravir Long-Acting Administered Intramuscularly in a 4-month Dosing Interval (Q4M) (NCT06741397) | ViiV Healthcare | 2024-12-20 |
| Efficacy and Safety of CDK4/6 Inhibitors Combined With Endocrine Therapy in HR+/HER2- Neoadjuvant Therapy for Early Breast Cancer (NCT07130643) | Xinhong Wu, PhD | 2024-12-20 |
| A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma (NCT06679985) | Coherus Oncology, Inc. | 2024-12-20 |
| A Dose-Range Study of Aleniglipron (GSBR-1290) in Participants Living With Obesity or Overweight With at Least One Weight-related Comorbidity (NCT06703021) | Gasherbrum Bio, Inc., a wholly owned subsidiary of Structure Therapeutics | 2024-12-20 |
| An Integrated Intervention Using a Pill Ingestible Sensor System (NCT06480578) | University of California, Los Angeles | 2024-12-19 |
| Milk Thistle Clinical Trial in Pediatric NAFLD (NCT06477146) | University Hospitals Cleveland Medical Center | 2024-12-19 |
| Efficacy and Safety of OsrhCT and Dimethicone Emulsion Before Upper Endoscopy on Visualization of the Gastric Mucosa. (NCT06722664) | Healthgen Biotechnology Corp. | 2024-12-19 |
| Comparative Imaging of XTR004 PET and MIBI SPECT in Borderline Coronary Stenosis (NCT07187895) | Sinotau Pharmaceutical Group | 2024-12-19 |
| Nicotinic Acid for the Treatment of Alzheimer's Disease (NCT06582706) | Indiana University | 2024-12-19 |
| Spatially Fractionated Radiotherapy for Tumor Treatment (NCT07774819) | Xu Zhi-yuan | 2024-12-19 |
| Cell Therapy with Anti-CD19 CAR-NK Cells in Patients with Relapsed or Resistant B-ALL (NCT06631040) | Shahid Beheshti University of Medical Sciences | 2024-12-19 |
| A Study to Evaluate the Safety and Immunogenicity of VLP-Polio in Infants and Toddlers (NCT06577298) | CanSino Biologics Inc. | 2024-12-19 |
| Dissolved Phase HXe-129 MRI: A Novel Biomarker to Quantify Pulmonary Pathology (NCT06856525) | Y. Michael Shim, MD | 2024-12-19 |
| Positive Dementia Caregiving: Clinical Trial of an Online Training Program (NCT06409455) | Education University of Hong Kong | 2024-12-19 |
| Safety and Efficacy of IMM01-STEM Against Placebo on Muscle Performance in Seniors With Obesity and Muscle Weakness (NCT06600581) | Immunis, Inc. | 2024-12-19 |
| Exploring the Feasibility of Silk Fibroin Surgical Mesh in Rotator Cuff Tears Repair Enhancement (NCT06766630) | Weiliang Shen, Ph.D., M.D. | 2024-12-19 |
| Sacituzumab Govitecan and Zimberelimab w/SRS in the Management of Metastatic Triple Negative Breast Cancer With Brain Metastases (NCT06238921) | H. Lee Moffitt Cancer Center and Research Institute | 2024-12-19 |
| A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease (NCT06500702) | Sanofi | 2024-12-19 |
| This is a Study Evaluating the Efficacy and Safety of LTG-001 for Acute Pain After Surgical Removal of Impacted Third Molars (NCT06774625) | Latigo Biotherapeutics | 2024-12-19 |
| A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis (NCT06718101) | AbbVie | 2024-12-19 |
| Pasireotide as Maintenance Treatment in Synovial Sarcoma and Desmoplastic Small Round Cell Tumor (NCT06456359) | University Hospital Heidelberg | 2024-12-19 |
| Zanzalintinib (XL-092) Plus Durvalumab and Tremelimumab in Unresectable Hepatocellular Carcinoma (ZENOBIA) (NCT06698250) | Anwaar Saeed | 2024-12-18 |
| VK2735 for Weight Management Phase 2 (Venture Oral Dosing) (NCT06828055) | Viking Therapeutics, Inc. | 2024-12-18 |
| Phase 2b Safety and Efficacy Study of CGB-500 Topical Ointment With 0.5% and 1% Tofacitnib for Treatment of Atopic Dermatitis (NCT06810050) | CAGE Bio Inc. | 2024-12-18 |
| Elranatamab in Relapsed/Refractory Multiple Myeloma (NCT06711705) | University of California, San Diego | 2024-12-18 |
| A Study to Evaluate the Safety, Tolerability and Efficacy of RZ-001 in Combination With Valganciclovir (VGCV) and Atezolizumab/Bevacizumab in Subjects With Hepatocellular Carcinoma (NCT06695026) | Rznomics, Inc. | 2024-12-18 |
| A Multicenter Study to Evaluate Safety, Tolerability, and Clinical Responses of DSP-1083 Into Subjects With Parkinson's Disease (NCT06753331) | Sumitomo Pharma America, Inc. | 2024-12-18 |
| A Study of 3mg Once Every Two Weeks Administration of Efsubaglutide Alfa Injection in Type 2 Diabetes Patients. (NCT06849843) | Shanghai Yinnuo Pharmaceutical Technology Co., Ltd. | 2024-12-18 |
| A Study of Barzolvolimab in Patients With Atopic Dermatitis (NCT06727552) | Celldex Therapeutics | 2024-12-18 |
| Generalization With AI Navigation Using StaRt (NCT06884943) | New York University | 2024-12-18 |
| A Phase Ib/II Study to Investigate the Safety of SHR-1819 in Children and Adolescents With Moderate-to-severe Atopic Dermatitis (NCT06713499) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2024-12-18 |
| GBS-NN/NN2 (50 µg of Each Fusion Protein [GBS-NN and GBS-NN2] in Combination With 500 µg Aluminum as Alhydrogel®) Given With and Without the Tdap Vaccine in Healthy Non-pregnant Women 18 to 49 Years of Age (NCT06494475) | Minervax ApS | 2024-12-17 |
| Aumolertinib Versus Osimertinib As First-line Therapy for Patients with EGFR Mutated Locally Advanced or Metastatic Non-small-cell Lung Cancer (NCT06752408) | Peking Union Medical College Hospital | 2024-12-17 |
| A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma (NCT06581406) | Replimune, Inc. | 2024-12-17 |
| Bioenergetic Effect of Pioglitazone in CLD-PH (NCT06336798) | Emory University | 2024-12-17 |
| RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis (NCT06359041) | Cabaletta Bio | 2024-12-17 |
| Effectiveness of Alternative Therapies in Maintaining Weight Loss Achieved by GLP-1 Medications Post-Cessation (NCT07092618) | AgelessRx | 2024-12-17 |
| Accelerating TMS for Cervical Dystonia (NCT06328114) | Duke University | 2024-12-17 |
| A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease (NCT06727604) | Immunovant Sciences GmbH | 2024-12-17 |
| A Study of PGN-EDO51 or Placebo in People With Duchenne Muscular Dystrophy Amenable to Exon 51-Skipping Treatment (NCT06833931) | PepGen Inc | 2024-12-17 |
| Efficacy and Safety of Sintilimab Combined with Nab-PP Plus Rh-endostatin in Locally Advanced/advanced and Recurrent Metastatic Squamous Non-small Cell Lung Cancer: a Single-arm, Multicenter Clinical Study (NCT06747169) | Jian-Guo Zhou, MD, PhD | 2024-12-17 |
| Ixovex-1 Single Agent and Combination Therapy (NCT06549946) | Psivac Ltd | 2024-12-17 |
| Phase 2 Study of Rapcabtagene Autoleucel in Myositis (NCT06665256) | Novartis Pharmaceuticals | 2024-12-17 |
| BrAin Metastasis in tripLe Negateive Breast Cancer: IvoneScimab and Trop2 ADC (NCT06793332) | Fudan University | 2024-12-17 |
| Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial (NCT06601933) | Columbia University | 2024-12-17 |
| Safety and Effectiveness of Valbenazine as Adjunct Therapy to Botulinum Toxin Injections in Cervical Dystonia (NCT06771323) | Virginia Commonwealth University | 2024-12-17 |
| Venetoclax for the Treatment of Patients With Relapsed Hairy Cell Leukemia (NCT06311227) | National Cancer Institute (NCI) | 2024-12-16 |
| A Study to Evaluate the Efficacy and Safety of MK-1167 in Participants With Alzheimer's Disease Dementia (MK-1167-008) (NCT06721156) | Merck Sharp & Dohme LLC | 2024-12-16 |
| Clinical Study on the Treatment of Herpes Zoster Pain With Dexmedetomidine Combined With Long-term High Voltage (NCT06978192) | Fenghui Deng | 2024-12-16 |
| Venetoclax + Azacitidine in Patients With Acute Myeloid Leukemia (NCT06668558) | Grupo Cooperativo de Estudio y Tratamiento de las Leucemias Agudas y Mielodisplasias | 2024-12-16 |
| Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation (NCT06501625) | Institut de Recherches Internationales Servier | 2024-12-16 |
| A Proof-of-Concept Study to Assess the Efficacy, Safety and Tolerability of Itepekimab (Anti--IL-33 mAb) in Participants With Chronic Rhinosinusitis Without Nasal Polyps (NCT06691113) | Sanofi | 2024-12-16 |
| A Study of the Efficacy and Safety of Brensocatib in Adults With Moderate to Severe Hidradenitis Suppurativa (HS) (NCT06685835) | Insmed Incorporated | 2024-12-16 |
| A Phase 2 Study to Assess the Safety of EI-1071 and the Effects of EI-1071 on Neuroinflammation in Alzheimer's Disease Patients (NCT06745583) | Elixiron Immunotherapeutics Inc. | 2024-12-16 |
| A Late Phase II Clinical Trial of KDT-3594 in Patients With Parkinson's Disease (NCT06722729) | Kissei Pharmaceutical Co., Ltd. | 2024-12-16 |
| A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors (NCT06747585) | Alentis Therapeutics AG | 2024-12-16 |
| A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) (NCT06667076) | Janssen Research & Development, LLC | 2024-12-16 |
| Suprachoroidal Administration in Subjects With Metastases to the Choroid (NCT06643884) | Aura Biosciences | 2024-12-16 |
| NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial (NCT06450041) | New Approaches to Neuroblastoma Therapy Consortium | 2024-12-16 |
| Amiodarone-Infused CardiaMend Patches for the Prevention of New-Onset POAF in Cardiac Surgery Subjects (NCT06730828) | Helios Cardio Inc. | 2024-12-16 |
| Stereotactic Radiosurgery in the Treatment of Essential Tremor (NCT06821906) | Maria Sklodowska-Curie National Research Institute of Oncology | 2024-12-16 |
| Prophylactic Intravenous Injection of Neostigmine Plus Atropine Versus Ketorolac on Post-dural Puncture Headache in Patients Undergoing Infraumbilical Surgeries (NCT06729047) | Assiut University | 2024-12-15 |
| Trilaciclib in Preventing Hematopoietic Suppression in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (NCT06714266) | Shandong Cancer Hospital and Institute | 2024-12-15 |
| Gabapentin and Pressor Response to Intubation (NCT06705101) | Liaquat National Hospital & Medical College | 2024-12-15 |
| Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in Adults (NCT06547151) | Amorphical Ltd. | 2024-12-15 |
| A Single-Arm, Phase Ⅰb Study of Golidocitinib Combined With Anti-PD-1 for the Treatment of Previously Treated NSCLC (NCT06690671) | Shanghai Chest Hospital | 2024-12-15 |
| Efficacy of Sublingual 5-MeO-DMT for Reducing Anxiety and Depression in MCI (NCT06812221) | Biomind Labs Inc. | 2024-12-15 |
| Gemcitabine/Cisplatin/Nab-Paclitaxel and Rilvegostomig in Resectable iCCA (NCT06569225) | University Health Network, Toronto | 2024-12-15 |
| Warm Versus Conventional 2% Lignocaine for IANB Efficacy (NCT06806202) | Armed Forces Institute of Dentistry, Pakistan | 2024-12-15 |
| A Study of XY03-EA Tablets in the Treatment of Acute Ischemic Stroke (NCT06755944) | Shijiazhuang Yiling Pharmaceutical Co. Ltd | 2024-12-15 |
| Tirellizumab Combined With TP Neoadjuvant Therapy in the Treatment of Early Oral Squamous Cell Carcinoma （HNC-SYSU-005） (NCT07267286) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2024-12-15 |
| SHAPE for ICP Assessment (NCT06571786) | Thomas Jefferson University | 2024-12-15 |
| Comparative Study Between Antihyperlipidemic Agents in Treatment of Cardiovascular Diseases (NCT07313124) | Beni-Suef University | 2024-12-15 |
| Effector and Memory Immune Responses to HPV Vaccination in Vietnamese Women Post Virus Exposure (NCT06681636) | National Institute of Hygiene and Epidemiology, Vietnam | 2024-12-14 |
| The Effects of Cannabigerol on Attention-Deficit/Hyperactivity Disorder (NCT06115603) | University of Arkansas, Fayetteville | 2024-12-14 |
| Phase 2b Imaging Study of RAD101 in Participants With Suspected Recurrent Brain Metastases (NCT06777433) | Radiopharm Theranostics, Ltd | 2024-12-13 |