| Post-Cardiac Surgery Acute Kidney Injury Prevention by Administration of Proton Pump Inhibitor (P2 Trial) (NCT06706258) | The University of Texas Health Science Center, Houston | 2025-01-24 |
| Indication of HSCT in Patients With Refractory/Relapse AA After First-line Standard Immunosuppressive Therapy Aged More Than 40 Years (NCT06646497) | Assistance Publique - Hôpitaux de Paris | 2025-01-24 |
| Carboplatin + Paclitaxel + Cetuximab (PCC) After Failure of Pembrolizumab +/- First-line Chemotherapy in Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (NCT06725368) | Centre Paul Strauss | 2025-01-24 |
| Study of Once-Daily Oral RGT001-075 Compared With Placebo in Adults With Obesity or Are Overweight With Weight-Related Health Conditions (NCT06867718) | Regor Pharmaceuticals Inc. | 2025-01-24 |
| PET/CT-Directed Free of Therapy for Metastatic RCC Patients With IMDC Favorable or Intermediate Risk (NCT07175480) | Jinling Hospital, China | 2025-01-24 |
| Feasibility Trial of Glofitamab in a Response Adapted Approach Incorporating Interim FDG PET and ctDNA to Optimize Primary Therapy of DLBCL (GRAIL) (NCT06050694) | University Health Network, Toronto | 2025-01-24 |
| COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty (NCT06809998) | Unity Health Toronto | 2025-01-24 |
| A Study of NTQ5082 Capsules in the Treatment of Paroxysmal Nocturnal Hemoglobinuria Patients (NCT06764303) | Nanjing Chia-tai Tianqing Pharmaceutical | 2025-01-23 |
| Therapy for Newly Diagnosed Patients With B-Cell Precursor Acute Lymphoblastic Leukemia and Lymphoma (NCT06533748) | St. Jude Children's Research Hospital | 2025-01-23 |
| Response to Exercise and Nitric Oxide in PAD (NCT06657976) | Northwestern University | 2025-01-23 |
| A Study to Investigate the Safety, Tolerability, and Preliminary Efficacy With AION-301 Administered by Intravenous Infusion Compared With Placebo Administered by Intravenous Infusion Investigational Intervention in Participants Aged 35 to 75 Years of Age With Chronic Kidney Disease (CKD) (NCT06721143) | AION Healthspan, Inc. | 2025-01-23 |
| Ubiquinone vs. Ubiquinol Supplementation (NCT06555575) | Trio Fertility | 2025-01-23 |
| A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer (NCT06609005) | Shenzhen Ionova Life Sciences Co., Ltd. | 2025-01-23 |
| A Study to Assess Recovery and Survival of Radiolabeled Apheresis Platelet Components Treated With the INTERCEPT Blood System for Platelets With LED Illuminator. (NCT06697223) | Cerus Corporation | 2025-01-23 |
| A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers. (NCT06697184) | BeOne Medicines | 2025-01-23 |
| Pharmacokinetics, Pharmacodynamics, Safety, and Preliminary Efficacy of Subcutaneous Injection of SHR-1905 in Adolescent Asthmatic Subjects - an Open-label, Single-dose Phase II Clinical Study (NCT06786455) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2025-01-23 |
| MZL-IPI Risk-adapted Targeted Therapy in Untreated MZL (NCT06793189) | Ruijin Hospital | 2025-01-23 |
| Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab (NCT06136546) | Massachusetts General Hospital | 2025-01-23 |
| Evaluating the Effectiveness and Tolerance of Baricitinib in the Treatment of Acute Alopecia Areata With Active Hair Shedding: A Prospective Open-Label Study (NCT06797310) | National Taiwan University Hospital | 2025-01-23 |
| Study of RSS0343 Tablets in Patients With Non-cystic Fibrosis Bronchiectasis (NCT06775340) | Jiangsu HengRui Medicine Co., Ltd. | 2025-01-22 |
| TIL Therapy in Non-small-cell Lung Cancer (NSCLC) Patients (NCT06455917) | University Hospital, Basel, Switzerland | 2025-01-22 |
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase II Clinical Trial to Evaluate the Efficacy and Safety of TVAX-008 Injection in Chronic Hepatitis B Patients (NCT07179653) | Grand Theravac Life Sciences (Nanjing) Co., Ltd. | 2025-01-22 |
| Long-Term PEA Safety Study (NCT06717867) | RDC Clinical Pty Ltd | 2025-01-22 |
| Perioperative Therapies in Locally Advanced Unresectable Gastric Cancer (NCT06630130) | Jeeyun Lee | 2025-01-22 |
| Nemtabrutinib With Rituximab for the Treatment of Patients With Mantle Cell Lymphoma (NCT06572618) | City of Hope Medical Center | 2025-01-22 |
| A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors (NCT06777316) | Cogent Biosciences, Inc. | 2025-01-22 |
| A Clinical Study on the Efficacy and Safety of Fruquintinib in Combination With PD-1 Monoclonal Antibody and Chidamide in Refractory MSS Metastatic Colorectal Cancer (NCT06979908) | The First Hospital of Jilin University | 2025-01-22 |
| Feasibility of Intravaginal Artesunate as Adjuvant HPV & Cervical Precancer Treatment in Kenya (NCT06519994) | UNC Lineberger Comprehensive Cancer Center | 2025-01-22 |
| A Study of SHJ002 Sterile Ophthalmic Solution for Myopia Control (NCT06579287) | Sunhawk Vision Biotech, Inc. | 2025-01-22 |
| Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma (NCT06478212) | Institut de Recherches Internationales Servier | 2025-01-22 |
| CTX-009 With Gemcitabine, Cisplatin, and Durvalumab as First-line Therapy in Patients With Unresectable or Metastatic Biliary Tract Cancers (NCT06548412) | M.D. Anderson Cancer Center | 2025-01-22 |
| Epco, Zanu, Ritux for R/R FL or MZL (NCT06563596) | Reid Merryman, MD | 2025-01-21 |
| AK112 and Cadonilimab Combined With Chemotherapy for 1L Treatment of Metastatic Pancreatic Cancer (NCT06646055) | Akeso | 2025-01-21 |
| Endocalyx in Treatment Resistent Hypertension (NCT06940011) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2025-01-21 |
| Intraglandular Treatment With Adipose-derived Mesenchymal Stem Cells in Patients With Xerostomia Due to Sjögren's Disease (NCT06805448) | Rigshospitalet, Denmark | 2025-01-21 |
| HAV Versus DAV/IAV Induction Regimen in Elderly Patients With AML (NCT06744556) | Institute of Hematology & Blood Diseases Hospital, China | 2025-01-21 |
| Advanced Imaging for Pulmonary Fibrosis (NCT06532071) | Peter Caravan | 2025-01-21 |
| A Trial of HRS-2189 in Combination With Fluvastatin±HRS-6209, or HRS-8080±HRS-6209, or HRS-6209+HRS-1358 in Breast Cancer Patients (NCT06679036) | Shandong Suncadia Medicine Co., Ltd. | 2025-01-21 |
| A Phase I/II Clinical Study of SHR-1681 for Injection in Patients With Advanced Solid Tumors (NCT06737731) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-01-21 |
| Pharmacokinetics, Efficacy and Safety of Twice Daily Dosing Regimen of Hydroxycarbamide Dispersible Tablets in Children With Sickle Cell Disease (NCT06578507) | Theravia | 2025-01-21 |
| PeRioperative Immunotherapy Combined With Sacituzumab Govitecan in Muscle Invasive blAdder Cancer (NCT06133517) | Fundación para el Progreso de la Oncología en Cantabria | 2025-01-20 |
| A Study to Test How Well BI 770371 is Tolerated by People With Cirrhosis Caused by a Liver Disease Called MASH (NCT06675929) | Boehringer Ingelheim | 2025-01-20 |
| Efficacy and Safety of Empagliflozin or Semaglutide in Overweight/Obese Patients With Type 1 Diabetes (NCT06762314) | Mostafa Bahaa | 2025-01-20 |
| Evaluation of Platelet Aggregability in Patients with Non-small Cell Lung Carcinomas (NCT06872541) | University of Sao Paulo | 2025-01-20 |
| Ketamine for Combined Depression and Alcohol Use Disorder (NCT06090422) | University Hospital of North Norway | 2025-01-20 |
| A Study of AC-101 Tablets in Participants With Moderate to Severe Active Ulcerative Colitis (NCT07083193) | Accro Bioscience (Suzhou) Limited | 2025-01-20 |
| Efficacy and Safety of Adjunctive Use of Rifaximin In Preventing Radiotherapy-induced Diarrhea in Cancer Patients (NCT06783153) | Mansoura University | 2025-01-20 |
| Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease (NCT05568498) | University of British Columbia | 2025-01-20 |
| Phase II Clinical Study of H001 Capsule in the Prevention of Venous Thromboembolism After Total Knee Arthroplasty (NCT06963320) | Livzon Pharmaceutical Group Inc. | 2025-01-20 |
| Study to Evaluate Adverse Events and Change in Disease Activity When Intravenously (IV) Infused Livmoniplimab is Used in Combination With IV Infused Budigalimab in Adult Participants With Urothelial Carcinoma (UC) (NCT06632951) | AbbVie | 2025-01-20 |
| CAR2219 CAR-T Cells for the Treatment of R/R B Cell Leukemia and Lymphoma (NCT06834529) | Affiliated Hospital to Academy of Military Medical Sciences | 2025-01-20 |
| A Phase II Study of TPF With PD-1 Inhibitor Induction Therapy for Locally Advanced Nasopharyngeal Carcinoma (NCT06781112) | Weiwei Zhang | 2025-01-20 |
| PhaseⅡClinical Trial of Oral Hexavalent Reassortant Rotavirus Attenuated Live Vaccine (Vero Cells) (NCT06967272) | Sinovac Life Sciences Co., Ltd. | 2025-01-20 |
| Neoadjuvant Radiotherapy Plus Targeted Therapy and Immunotherapy vs. Targeted Therapy Plus Immunotherapy in Resectable HNSCC (NCT06804850) | West China Hospital | 2025-01-20 |
| Effect and Safety of Fexofenadine Hydrochloride vs Placebo in Patients With Acute Myocardial Infaction: A Randomized Clinical Trial (NCT06548204) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-01-20 |
| A Study to Assess Adverse Events and How Intravenously (IV) Infused Telisotuzumab Vedotin (ABBV-399) Moves Through the Body as a Monotherapy in Adult Participants With Previously Treated Non-Squamous Non-Small Cell Lung Cancer (NSCLC) (NCT06568939) | AbbVie | 2025-01-20 |
| Avapritinib Combined With Azacitidine and Venetoclax in the Treatment of Relapsed AML After Allo-HSCT (NCT06783790) | Institute of Hematology & Blood Diseases Hospital, China | 2025-01-20 |
| Evaluation of the Safety and Tolerability of Gemini in Subjects With Stage 3-4 Chronic Kidney Disease. (NCT06863467) | Revelation Biosciences, Inc | 2025-01-20 |
| Short-course Radiotherapy Followed by CAPOX and Ivonescimab for Locally Advanced Rectal Cancer (NCT06760520) | The First Affiliated Hospital of Zhengzhou University | 2025-01-20 |
| Dose Individualization of Chemotherapy in Patients With Gastrointestinal Cancers Lacking a Specific Liver Enzyme (NCT06475352) | UNICANCER | 2025-01-20 |
| Evaluating the Impact of Adjuvant Use of Beta Blockers on Clinical Outcomes in Patients With Traumatic Brain Injury (NCT06836856) | Mansoura University | 2025-01-20 |
| Immune Reconstitution Monitoring and Pneumococcal Vaccination in Patients Treated With CAR-T Cells (NCT07071909) | UNC Lineberger Comprehensive Cancer Center | 2025-01-20 |
| TAR-0520 Gel in EGFR Inhibitor-induced Folliculitis (NCT06818058) | Tarian Pharma | 2025-01-20 |
| Pragmatic Trial of Psilocybin Therapy in Palliative Care (NCT05403086) | Charles S. Grob, M.D. | 2025-01-19 |
| Evaluating the Efficacy and Safety of of HSK44459 in People With Idiopathic Pulmonary Fibrosis (NCT06764862) | Haisco Pharmaceutical Group Co., Ltd. | 2025-01-17 |
| HX009+ IN10018 With or Without Standard Chemotherapy for Advanced Solid Tumours (NCT06708663) | Hangzhou Hanx Biopharmaceuticals, Ltd. | 2025-01-17 |
| Clinical Study to Evaluate Debio0123 + Sacituzumab Govitecan Combination in TNBC or HR+/HER2- Advanced Breast Cancer (NCT06612203) | MedSIR | 2025-01-17 |
| Optimizing HFrEF Patients Using BaroStim and CardioMems (NCT07399587) | Northwell Health | 2025-01-17 |
| Evaluation of JSKN016 in the Treatment of Advanced Non-small Cell Lung Cance： a Phase II Clinical Study (NCT06775483) | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | 2025-01-17 |
| Copaíba-based Mouthwash in Oral Mucotitis Prevention and Treatment in Oral Cancer Patients During Radioteraphy (NCT06708702) | Instituto Nacional de Cancer, Brazil | 2025-01-17 |
| Krill Oil for Pain in Elders (NCT06580912) | University of Florida | 2025-01-17 |
| Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma (NCT06517888) | Akouos, Inc. | 2025-01-17 |
| A Study to Evaluate the Efficacy and Safety of GDC-8264 in Preventing Cardiac Surgery-Associated Acute Kidney Injury (AKI) and Major Adverse Kidney Events (MAKE) (NCT06602453) | Genentech, Inc. | 2025-01-17 |
| Effects of Allogenic Umbilical Cord-Derived Mesenchymal Stem Cells on Patients With Rotator Cuff Disease (NCT06794294) | Seoul National University Hospital | 2025-01-17 |
| A Study of AK129 With or Without AK117 in PD(L)1-refractory Classic Hodgkin Lymphoma (NCT06642792) | Akeso | 2025-01-17 |
| 9MW2821 + Toripalimab vs 9MW2821 for 1st Line Locally Advanced or Metastatic Urothelial Carcinoma (NCT06823427) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2025-01-17 |
| Antiretrovirals Combined With Antibodies for HIV-1 Cure In Africa (NCT06205602) | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 2025-01-17 |
| A Phase 2 Study and Open-Label Extension of NEU-411 in Companion Diagnostic-Positive Participants With Early Parkinson's Disease (NCT06680830) | Neuron23 Inc. | 2025-01-17 |
| Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer (NCT06824064) | Riboscience, LLC. | 2025-01-17 |
| A Phase II Clinical Trial of the Safety and Efficacy of SAL0120 in Patients With Chronic Kidney Disease (CKD) (NCT07716618) | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 2025-01-17 |
| Sintilimab Combined With Chemotherapy as Adjuvant Treatment for Phase III GC and GEJ (NCT06761846) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-01-17 |
| Azacitidine Combined with Donor Lymphocyte Infusion for Acute Myeloid Leukemia Post-transplant Relapse Prevention. (NCT06754540) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2025-01-16 |
| CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma With Thiotepa-based Autologous Stem Cell Transplant (NCT06687772) | Washington University School of Medicine | 2025-01-16 |
| Enhancing Readability of Lay Abstracts and Summaries for Medical Knowledge Using Generative Artificial Intelligence (BRIDGE AI 3) (NCT07568444) | University of Southern California | 2025-01-16 |
| A Study of Glofitamab-based Treatment in People With Diffuse Large B-cell Lymphoma (NCT06765317) | Memorial Sloan Kettering Cancer Center | 2025-01-16 |
| A Study of ONO-1110 in Patients With Major Depressive Disorder (NCT06792136) | Ono Pharmaceutical Co., Ltd. | 2025-01-16 |
| Intravenous Ascorbate Plus Gemcitabine/Carboplatin: A Novel and Cost-Effective Alternative With Evident Efficacy in Patients With Muscle Invasive Bladder Cancer (NCT06493370) | University of Kansas Medical Center | 2025-01-16 |
| Fimepinostat, Combination HDAC and Pi3-kinase Inhibitor Tumor-Directed Therapy for Cushing Disease (NCT05971758) | University of California, Los Angeles | 2025-01-16 |
| A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Chordoma (NCT06787664) | Sichuan Baili Pharmaceutical Co., Ltd. | 2025-01-16 |
| Reinforced Pancreaticojejunostomy With or Without glubran2 (NCT06756074) | Minia University | 2025-01-15 |
| CAbotégravir LENacapavir DUal Long Acting (NCT06657885) | Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba | 2025-01-15 |
| Tolerability, Safety, and Immunogenicity of Tetravalent Inactivated Enterovirus Vaccine (Vero Cell). (NCT06754384) | Sinovac Biotech Co., Ltd | 2025-01-15 |
| Standardized Microbiota Transplant Therapy in Crohn's Disease (NCT06631586) | University of Minnesota | 2025-01-15 |
| Phase 1/Phase 2a Study of AERO-007 Inhalation Solution, a Nebulized LABA/LAMA Combination for Maintenance Treatment of COPD (NCT06841640) | AeroRx Therapeutics Inc. | 2025-01-15 |
| Evaluation of a Pragmatic Approach to Adoptive Cell Therapy (ACT) Using an IL2 Analog (ANV419) vs High Dose IL2 After Tumor Infiltrating Lymphocytes (TIL) Therapy in Patients With Melanoma, NSCLC and Cervical Cancer (PragmaTIL) (NCT06630611) | Vall d'Hebron Institute of Oncology | 2025-01-15 |
| JSKN033 in Chinese Subjects with Advanced Malignant Tumors (NCT06770881) | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | 2025-01-15 |
| A Clinical Study of NAD in the Treatment of Immune Thrombocytopenia (NCT06776510) | Institute of Hematology & Blood Diseases Hospital, China | 2025-01-15 |
| Adjuvant Treatment of ALK-positive Non-small Cell Lung Cancer with Ensartinib Guided by MRD (NCT06780839) | Peking University Cancer Hospital & Institute | 2025-01-15 |
| Cirtuvivint in Selected Advanced Soft-Tissue Sarcomas (NCT07032285) | Asociación Europea y Latinoamericana SELNET para la Investigación en Sarcomas | 2025-01-15 |
| Dietary Supplements to Treat Radiation-Induced Rectal Injury (NCT06776016) | Sixth Affiliated Hospital, Sun Yat-sen University | 2025-01-15 |