| Treatment for Advanced Non-small Cell Lung Cancer With Actionable Genomic Alterations After Targeted Treatment and Chemotherapy (An Expanded Lung-MAP Treatment Trial) (NCT07393555) | SWOG Cancer Research Network | 2026-08-07 |
| Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study (NCT07705022) | University of Michigan | 2026-08-07 |
| SKB264 in Combination With SKB118 for Non-Small Cell Lung Cancer (NCT07697586) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2026-08-07 |
| Study of LNP.UCD.ABE in Patients With Urea Cycle Disorders (NCT07667387) | Rebecca Ahrens-Nicklas | 2026-08-07 |
| Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities (NCT07752979) | AbbVie | 2026-08-07 |
| ACX-362E [Ibezapolstat] for Oral Treatment of Recurrent Clostridioides Difficile Infection (NCT07513285) | Acurx Pharmaceuticals Inc. | 2026-08-06 |
| A Phase 2 Study of HS-20118 to Evaluate the Efficacy and Safety in Participant With Moderate-to-Severe Plaque Psoriasis (NCT07765628) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2026-08-06 |
| Psilocybin to Treat Depression in Spinal Cord Injury (NCT07251491) | James J. Peters Veterans Affairs Medical Center | 2026-08-06 |
| Tegoprazan Versus Lansoprazole for Endoscopic Ulcer Healing in Bleeding Peptic Ulcers (NCT07708545) | Indonesia University | 2026-08-06 |
| Alzheimer's Disease Research Center (ADRC) PET Component Study (NCT07758660) | Patrick Lao | 2026-08-06 |
| A Study Evaluating the Efficacy and Safety of Momelotinib in Participants With Vacuoles, E1-enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) Syndrome (NCT07569081) | GlaxoSmithKline | 2026-08-05 |
| NeoAdjuvant, Spare-Adjuvant (NASA) in Stage IIIB-IV (M1a) Melanoma (NCT07740941) | UNC Lineberger Comprehensive Cancer Center | 2026-08-05 |
| A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of KIT2014 in Patients With Moderate to Severe COPD (NCT07668518) | Kither Biotech Srl | 2026-08-05 |
| Cannabis for Obesity Trial (NCT06137365) | Joshua A. Lile, Ph.D. | 2026-08-05 |
| Metronomic Oral Paclitaxel Monotherapy for Advanced HER2-Negative Breast Cancer: A Two-Stage Dose-Finding and Expansion Study (NCT07602907) | Zhejiang Cancer Hospital | 2026-08-04 |
| Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions (NCT07654283) | AusperBio Therapeutics Inc. | 2026-08-04 |
| Safety and Efficacy of STL303 In Patients With Primary Immunoglobulin A (IgA) Nephropathy (NCT07606352) | Sitala Bio LTD | 2026-08-04 |
| A Study to Assess the Tolerability of Ianalumab (VAY736) With Investigator's Choice Thrombopoietin Receptor Agonist (IC TPO-RA) in Patients With Primary Immune Thrombocytopenia (ITP) (NCT07421167) | Novartis Pharmaceuticals | 2026-08-04 |
| Exercise and Intranasal Insulin in Type 2 Diabetes (NCT07675499) | Rutgers, The State University of New Jersey | 2026-08-03 |
| CK0801 for Treatment of Aplastic Anemia (NCT07499102) | Cellenkos, Inc. | 2026-08-03 |
| Continued Access to Avutometinib in Combination With Defactinib in Patients With Recurrent Low-Grade Serous Ovarian Cancer (LGSOC) (NCT07747506) | Verastem, Inc. | 2026-08-03 |
| A Study of Patritumab Deruxtecan (HER3-DXd) in Combination With Trastuzumab Deruxtecan (T-DXd) in Participants With HR-Positive, HER2-Low or HER2-Ultralow Unresectable or Metastatic Breast Cancer (NCT07701941) | Daiichi Sankyo | 2026-08-03 |
| A Study of More Frequent Dosing of VCN-01 Combined With Standard Chemotherapy in Patients With Newly Diagnosed Metastatic Pancreatic Cancer (NCT07701486) | Theriva Biologics SL | 2026-08-03 |
| Study of Alternative and Approved Dosing Regimens of Belantamab Mafodotin, Bortezomib, and Dexamethasone (BVd) in Participants With Relapsed/Refractory Multiple Myeloma (NCT07614360) | GlaxoSmithKline | 2026-08-03 |
| Focused Ultrasound for PTSD in Veterans (NCT06820138) | VA Office of Research and Development | 2026-08-03 |
| Phase I/II Clinical Trial of UX-DA003 Injection for the Treatment of Patients With Parkinson's Disease (NCT07733349) | Shanghai UniXell Biotechnology Co., Ltd | 2026-08-03 |
| Study of SIR2501 in Solid Tumor Patients Receiving Paclitaxel (NCT07765446) | Sironax USA, Inc. | 2026-08-03 |
| A Study of SSGJ-613 in Gout Participants Initiating Urate-Lowering Treatment (NCT07708181) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2026-08-02 |
| A Study of the Metabolic Reconstruction Oral Biologics (Gut-X-001) Medication in People With Alzheimer's Disease (ESCAPE-AD) (NCT07591727) | Beijing Tiantan Hospital | 2026-08-01 |
| A Study of MRG007 Combination Therapy for Advanced Colorectal Cancer (NCT07737600) | Lepu Biopharma Co., Ltd. | 2026-08-01 |
| Neoadjuvant Disitamab Vedotin, Toripalimab, and Radiotherapy for High-risk UTUC ( LUXUS07.1 ) (NCT07720921) | Peking University First Hospital | 2026-08-01 |
| Multi-Cohort Study of Zeprumetostat Combinations for Relapsed/Refractory PTCL (NCT07724782) | Tianjin Medical University Cancer Institute and Hospital | 2026-08-01 |
| Clinical Study of Local and Systemic Biological Impact of GLP1/GIP-Receptor Agonists in Patients With Breast Cancer: The CLARA Trial (NCT07676331) | Universitaire Ziekenhuizen KU Leuven | 2026-08-01 |
| A Study of BL-M09D1 in Patients With Locally Advanced or Metastatic Gynecological Malignancies and Other Solid Tumors (NCT07769229) | Sichuan Baili Pharmaceutical Co., Ltd. | 2026-08-01 |
| Sac-TMT for Active TNBC Brain Metastases (NCT07458113) | Yale University | 2026-08-01 |
| ANO31905 in Combination With Chemotherapy for CLDN18.2-Positive Locally Advanced Unresectable or Metastatic Pancreatic Cancer (NCT07444541) | Anova Innovation Limited | 2026-08-01 |
| Inhaled DMT for Major Depressive Disorder (NCT07562191) | Universidade Federal do Rio Grande do Norte | 2026-08-01 |
| A Phase 2 Study of Sirolimus for Injection (Albumin-bound) in Patients With Progressive or Symptomatic Epithelioid Hemangioendothelioma (NCT07684287) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2026-08-01 |
| Study of TX000045 in Participants With Pulmonary Hypertension Due to Interstitial Lung Disease (NCT07473700) | Tectonic Operating Company, Inc. | 2026-08-01 |
| Drospirenone-Primed Ovarian Stimulation Versus GnRH Antagonist Protocol in Poor Ovarian Responders Undergoing Freeze-All IVF/ICSI (NCT07736261) | Ahmed Saad | 2026-08-01 |
| Clinical Study Comparing Diosmin vs Rebamipide as Adjuvant Therapies vs Conventional Therapy in Patients With Rheumatoid Arthritis (NCT07745426) | Tanta University | 2026-08-01 |
| Dynamic Risk-adapted EBV-DNA and MRI-guided De-concurrent Chemotherapy in Nasopharyngeal Carcinoma (NCT07762976) | Fudan University | 2026-08-01 |
| FAPI PET Imaging - An Exploratory Study (NCT07705074) | Martin Huellner | 2026-08-01 |
| Effects of Infusion Timing on Treatment Response in Solid Tumors (NCT07630168) | UNC Lineberger Comprehensive Cancer Center | 2026-08-01 |
| A Dose-Finding Study of Amogammadex Sodium for Reversing Vecuronium and Rocuronium-Induced Neuromuscular Blockade (NCT07595393) | Amckaus PTY LTD. | 2026-08-01 |
| The Efficacy of CAPCT in Patients With PTCL (NCT07746245) | The First Affiliated Hospital with Nanjing Medical University | 2026-08-01 |
| Early Aldo Blockade in Subclinical PA (NCT07727252) | Xinjiang Medical University | 2026-08-01 |
| Bladder-Sparing Treatment With Disitamab Vedotin and Toripalimab With or Without Pelvic Lymph Node Dissection in Bladder Cancer (NCT07756008) | Tianjin Medical University Second Hospital | 2026-08-01 |
| Upadacitinib in Treatment of JAK/STAT Pathway Disorders With Activating Mutations (NCT07670156) | Lisa Satter | 2026-08-01 |
| Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains (NCT07436611) | AFT Pharmaceuticals, Ltd. | 2026-08-01 |
| A Study to Evaluate the Efficacy and Safety of ICP-488 in Participants With Primary Sjögren's Syndrome (NCT07727486) | Beijing InnoCare Pharma Tech Co., Ltd. | 2026-08-01 |
| Effect of Vasopressin Versus Norepinephrine on Post-operative Mean Pulmonary Arterial Pressure Following Pulmonary Endarterectomy Surgery, (NCT07614438) | Fondation Hôpital Saint-Joseph | 2026-08-01 |
| Tirzepatide in Women With Obesity and Endometrial Intra-epithelial Neoplasia or Grade 1 Endometrial Cancer (NCT07078838) | UNC Lineberger Comprehensive Cancer Center | 2026-08-01 |
| Intensive Locoregional Chemoimmunotherapy, Intradermal Autologous Alpha-DC1 Vaccines, and Systemic Pembrolizumab for Advanced-Stage Ovarian Cancer (NCT07634094) | Kalinski, Pawel, MD, PhD | 2026-08-01 |
| Safety and Efficacy Study of GEB-101 Injection in Subjects With TGFBI-related Corneal Dystrophy (NCT07750678) | GenEditBio Limited | 2026-08-01 |
| RiMO-HNC-NEO1: Phase 2 Study of RiMO-301 and Hypofractionated Radiotherapy With Pembrolizumab for the Neoadjuvant Treatment of Resectable, Locally Advanced Head-Neck Cancer (NCT07732634) | University of Illinois at Chicago | 2026-08-01 |
| ELDORADO: Elranatamab Versus Daratumumab in Combination With RVd Lite for Newly Diagnosed Transplant Ineligible/Deferred Multiple Myeloma (NCT07247097) | Massachusetts General Hospital | 2026-08-01 |
| Verapamil Effect in Cystic Fibrosis-related Dysglycemia (NCT07688070) | Rhode Island Hospital | 2026-08-01 |
| Safety and Feasibility of FMT for Immune Recovery After HSCT (NCT07755319) | The First Affiliated Hospital of Soochow University | 2026-08-01 |
| Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) (NCT07149649) | Swiss Cancer Institute | 2026-08-01 |
| Phase 2a Dose Finding Study of Nu-3 Gel in Subjects With Mild iDFU (NCT07565506) | Lakewood-Amedex Inc | 2026-08-01 |
| A Clinical Study of SHR-9839 as Monotherapy or in Combination With Chemotherapy Plus Adebrelimab Versus Chemotherapy Plus Adebrelimab in Patients With Advanced Esophageal Squamous Cell Carcinoma (NCT07751341) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2026-08-01 |
| The Clinical Study of Adalimumab Combined With Other Anti-tumor Therapy as a Treatment for Resectable Non-small Cell Lung Cancer (NCT07704645) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2026-08-01 |
| Pembrolizumab Plus Lenvatinib in REcurrent ccRCC Patients Failing permbroLizUmab aDjuvant trEatment (NCT07460206) | Gruppo Oncologico Italiano di Ricerca Clinica | 2026-08-01 |
| Ivonescimab Combined With Chemoradiotherapy in High-Risk Locoregionally Advanced Nasopharyngeal Carcinoma (NCT07064902) | Sun Yat-sen University | 2026-08-01 |
| Evaluating Intranasal Oxytocin (TNX-1900) for Pain Relief and Recovery After Pituitary Surgery (NCT07730294) | Yale University | 2026-08-01 |
| A Phase IIb/III Clinical Study to Evaluate the Efficacy and Safety of APC101 in Patients With Postherpetic Neuralgia. (NCT07599800) | Andros Pharmaceuticals Co., Ltd. | 2026-08-01 |
| PRA-216 COPD Safety and Biomarker Study (NCT07730281) | Prana Therapies Inc | 2026-08-01 |
| A Phase I/II Open-label, Single-arm, Multicenter Clinical Study to Evaluate the Safety and Efficacy of FKC289 in Subjects With Relapsed/Refractory Membranous Nephropathy (NCT07765537) | Shenzhen Fosun Kairos Biotechnology Co., Ltd. | 2026-08-01 |
| Sancai Fengsui Decoction for RTOM: A Multicenter RCT (NCT07692997) | Nanfang Hospital, Southern Medical University | 2026-08-01 |
| A Phase 1/2 Study of KK2430 in Participants With Hematologic Neoplasms (NCT07629726) | Kyowa Kirin Co., Ltd. | 2026-08-01 |
| Metyrapone Study for Patients Diagnosed With Mild Autonomous Cortisol Secretion - MACS (NCT07138274) | Mayo Clinic | 2026-08-01 |
| A Phase II Exploratory Study of Sacituzumab Tirumotecan Combined With Envafolimab for TROP2-Positive Advanced Biliary Tract Cancers Previously Treated With First-Line Immunotherapy Combined With Chemotherapy. (NCT07729033) | Tianjin Medical University Cancer Institute and Hospital | 2026-08-01 |
| Tislelizumab in Combination With Bevacizumab and Capecitabine in Advanced Solid Tumors With Evaluation in Immunotherapy-Resistant and Central Nervous System Disease (NCT07681297) | National University Hospital, Singapore | 2026-08-01 |
| Becotatug Vedotin Plus Tislelizumab and Low-Dose Lenvatinib for Advanced Esophageal Squamous Cell Carcinoma, Phase II (NCT07686926) | Tianjin Medical University Cancer Institute and Hospital | 2026-08-01 |
| Safety Lead-In Study of a Repurposed Drug Added to the Combination of Len Plus Pem (NCT05106127) | Evergreen Therapeutics, Inc. | 2026-08-01 |
| Safety and Efficacy of BMS-986504 in Unresectable Malignant Peripheral Nerve Sheath Tumor (NCT07549022) | Ankit Mangla, MD | 2026-08-01 |
| An Open Label, Single Treatment, Single Arm, Multiple Dose Phase-2 Study to Evaluate the Pharmacokinetics, Safety, and Clinical Performance of EscharEx (EX-03) in Participants With Venous Leg Ulcers (NCT07692178) | MediWound Ltd | 2026-08-01 |
| A Study of Elranatamab Outpatient Administration in Patients With Relapsed/Refractory Multiple Myeloma (NCT07637578) | SCRI Development Innovations, LLC | 2026-08-01 |
| Upfront Chemotherapy With Radiation Therapy (CRT) Followed by Chemotherapy in Localized Esophageal Adenocarcinoma (NCT07603375) | Duke University | 2026-08-01 |
| HMA-Venetoclax Induction in Newly Diagnosed AML (NCT07748455) | Pakistan Blood and Marrow Transplant (PBMT) Group | 2026-08-01 |
| HS235 Study in Obese Participants With Pulmonary Hypertension and Heart Failure With Preserved Ejection Fraction (HFpEF) (NCT07123779) | 35Pharma Inc | 2026-08-01 |
| Effect of GnRH Agonist in FET (NCT07653282) | Assiut University | 2026-08-01 |
| A Randomized, Double-blind, Placebo-controlled Study Evaluating the Effect of LAE102 Injection in Combination With Tirzepatide on Body in Obese Participants (NCT07671391) | Shanghai Zhongshan Hospital | 2026-08-01 |
| Study of Triheptanoin for the Prevention of Hypoglycemia in Patients With Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD) (NCT06067802) | Jerry Vockley, MD, PhD | 2026-08-01 |
| Neoadjuvant Short-course Hypofractionated Radiotherapy Plus Adebrelimab and Platinum Chemotherapy in Locally Advanced Cervical Cancer: A Single-arm Phase II Trial (NCT07731828) | The First Affiliated Hospital with Nanjing Medical University | 2026-08-01 |
| Perioperative Finotonlimab Plus Chemotherapy in Untreated Stage II HNSCC (NCT07751276) | Yanjie Zhang, MD | 2026-08-01 |
| Adductor Canal Block: Efficacy in Postoperative Pain Management for Cardiac Surgery (NCT07732465) | Montreal Heart Institute | 2026-08-01 |
| A Study to Evaluate Safety and Efficacy of ALKS 7290 Compared With Placebo in Adult Participants With Attention Deficit Hyperactivity Disorder (ALKS 7290-201) (NCT07755410) | Alkermes, Inc. | 2026-08-01 |
| Vebotolimab Combined With Ptorlimab for EGFR-positive Refractory Advanced Biliary Tract Malignancies (NCT07472933) | West China Hospital | 2026-08-01 |
| A Multicenter Exploratory Clinical Study of Iruplaltinib Combined With Pemetrexed as Neoadjuvant Therapy for Resectable ALK-Positive Non-Squamous Non-Small Cell Lung Cancer (NCT07771764) | First Affiliated Hospital of Fujian Medical University | 2026-08-01 |
| XTX501 in Patients With Metastatic Non-Small Cell Lung Cancer and Advanced Solid Tumors (NCT07688577) | Xilio Development, Inc. | 2026-08-01 |
| Phase II Study of Becotatug Vedotin Plus Pucotenlimab for Advanced Refractory Solid Tumors With EGFR-Positive (NCT07712029) | Tianjin Medical University Second Hospital | 2026-08-01 |
| Evaluating the Addition of OK-1 Weekly Paclitaxel in Patients With Endometrial Cancer (NCT07737795) | University of Oklahoma | 2026-08-01 |
| Restoring Sinus Rhythm Using Dual-Shock Technique in Patients With Atrial Fibrillation (NCT07560644) | Martín Negreira Caamaño, MD, PhD | 2026-08-01 |
| Neoadjuvant Chemo-Immunotherapy and Surgical Resection in Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node or Other High Risk Features (NCT06449313) | Georgetown University | 2026-08-01 |
| Effect of Testosterone on Elderly Frail Men With Testosterone Deficiency (NCT07512323) | Rune Skovgaard Rasmussen | 2026-08-01 |
| Neoadjuvant Propranolol Plus SOX and Toripalimab for Locally Advanced Gastric/GEJ Adenocarcinoma (NCT07727993) | Ting Liu | 2026-08-01 |
| A Study to Evaluate Claudin 18.2-Directed ADC LCB02A in Advanced Solid Tumors (NCT07460375) | LigaChem Biosciences, Inc. | 2026-08-01 |
| The Many Roads to Trauma Recovery: A Clinical Trial Comparing Empirically Supported Treatments for Veterans With Co-Morbid Posttraumatic Stress and Substance Use Disorder Symptoms (NCT07756723) | Coatesville VA Medical Center | 2026-08-01 |