| Neoadjuvant Chemotherapy Combined With Bispecific Antibody Versus Monoclonal Antibody in Locally Advanced NSCLC (NCT06837948) | Shanghai Pulmonary Hospital, Shanghai, China | 2025-02-18 |
| Tailored Exercise Training Study Among Adults With HFpEF (NCT07223242) | University of Texas Southwestern Medical Center | 2025-02-18 |
| Efficacy and Safety of AL-001 Ophthalmic Injection in Subjects with WAMD (NCT06839339) | Beijing Anlong Biopharmaceutical Co., Ltd. | 2025-02-18 |
| A Study of HRS-5346 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events (NCT06816264) | Shandong Suncadia Medicine Co., Ltd. | 2025-02-18 |
| Study of Novel Treatment Combination Therapies in Participants With Head and Neck Squamous Cell Carcinoma Regardless of PD-L1 Expression Status; Substudy-01 (NCT06727565) | Gilead Sciences | 2025-02-18 |
| Ligufalimab and Cadonilimab in Advanced Liver Cancers (NCT06789848) | University of Texas Southwestern Medical Center | 2025-02-18 |
| DOVIPA, a Study Evaluating Efficacy and Safety of DOstarlimab and VItamin D3 With mFOLFIRINOX in PAncreatic Cancer (NCT06757244) | Hopital Foch | 2025-02-18 |
| Perioperative Treatment of Sunvozertinib in Stage II-IIIB NSCLC (NCT06864624) | Tang-Du Hospital | 2025-02-18 |
| A Study of SHR-1826 for Injection in Combination With Other Antitumor Therapies in Subjects With NSCLC (NCT06754930) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-02-18 |
| A Study to Assess How Vaborem® is Taking up in the Body and Tolerated in Paediatric Patients With Gram Negative Infections, Including But Not Restricted to Complicated Urinary Tract Infections (NCT06828848) | Menarini Group | 2025-02-18 |
| Efficacy of Varenicline Tartrate in Treating Frequent Premature Ventricular Contractions (NCT06780215) | Yihan Chen | 2025-02-17 |
| Comparison of Ustekinumab, Infliximab and Combination Therapy in Moderately to Severely Active Ulcerative Colitis (NCT06453317) | Medical University of Lodz | 2025-02-17 |
| POLA-R-CHP in the First-line Treatment of Transformed DLBCL (NCT06743945) | Fudan University | 2025-02-17 |
| A Study of BMS-986482 Alone or as Combination Therapy in Participants With Advanced Solid Tumors (NCT06697197) | Bristol-Myers Squibb | 2025-02-17 |
| Neoadjuvant Nivolumab Plus Ipilimumab in Resectable NSCLC (GALAXY 3) (NCT06926790) | The First Affiliated Hospital of Guangzhou Medical University | 2025-02-17 |
| Substance Misuse and Family Violence Treatment Fathers (NCT06650267) | Yale University | 2025-02-17 |
| Effectiveness and Performance of an Optical Biopsy Technology for Esophageal Cancer in Brazil and the United States (NCT06435286) | Baylor College of Medicine | 2025-02-17 |
| Combination Therapy of AK112 With Chemotherapy and/or Olaparib in Platinum-sensitive Ovarian Cancer (NCT06686030) | Akeso | 2025-02-17 |
| A Study of DM002 in Patients With Advanced Solid Tumors (NCT06751329) | Xadcera Biopharmaceutical (Suzhou) Co., Ltd. | 2025-02-17 |
| IN10018 With Nab-Paclitaxel and Cadonilimab for Metastatic or Recurrent Gastric-Type Cervical Adenocarcinoma: Phase 2 Trial (NCT06654011) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-02-17 |
| Head-to-head Study of Tegoprazan 50 mg BID Plus Amoxicillin 1 g TID vs. Vonoprazan 20 mg BID Plus Amoxicillin 1 g TID for H. Pylori Eradication (NCT07242456) | First People's Hospital of Hangzhou | 2025-02-17 |
| Newly Diagnosed Stage III/IV Ovarian Cancer, Neoadjuvant Carbo/Taxol/Pembro, Maintenance Olaparib/Pembro (NCT05952453) | University of Alabama at Birmingham | 2025-02-17 |
| Transdermal Microneedle Lignocaine Delivery Versus EMLA Patch for Topical Analgesia Before Venepuncture Procedure To Adults in Clinical Setting (NCT05694858) | Universiti Kebangsaan Malaysia Medical Centre | 2025-02-17 |
| Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease (NCT06847321) | Lighthouse Pharmaceuticals, Inc. | 2025-02-17 |
| Reduced Length of ADT and ARTA With XRT in High-Risk Prostate Cancer (RELAX): A Randomised Trial (NCT06818682) | Tata Memorial Centre | 2025-02-17 |
| Heavy Strength Training in Head and Neck Cancer Survivors (NCT06289049) | University of Alberta | 2025-02-17 |
| A Prospective Study of Cadonilimab in Hepatocellular Carcinoma After Radical Surgery With High Risk of Recurrence (NCT06851104) | Guangxi Medical University | 2025-02-16 |
| Orlistat Overcoming Third-generation EGFR-TKI Resistance (NCT06818955) | Ping Peng | 2025-02-16 |
| Clinical Trial of Recombinant Herpes Zoster Vaccine (CHO Cell) in Healthy Chinese Population Aged 40 Years and Older (NCT06851832) | Ab&B Bio-tech Co., Ltd.JS | 2025-02-16 |
| Clinical Study of Fasudil Hydrochloride and PD1 Inhibitor Combined With Androgen Deprivation in Neoadjuvant Therapy of Prostate Cancer (NCT06861192) | baotai Liang | 2025-02-16 |
| Heterogeneity of 68Ga-FAPI Uptake As Imaging Biomarker in T-DXd Treatment for Brain Metastasis of HER2 Positive Breast Cancer (NCT06797622) | Fudan University | 2025-02-15 |
| TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-ALL (NCT06481735) | Chinese PLA General Hospital | 2025-02-15 |
| A Clinical Study Evaluating the Efficacy of Systemic Chemotherapy and Immune Checkpoint Inhibitors Combined With Hyperthermic Intraperitoneal Chemotherapy in the Treatment of Gastric Cancer Patients With Peritoneal Metastasis (NCT06685887) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-02-15 |
| MB-105 in Patients With CD5 Positive T-cell Lymphoma (NCT06534060) | March Biosciences Inc | 2025-02-15 |
| A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Recombinant Herpes Zoster Vaccine (NCT06801509) | Sinocelltech Ltd. | 2025-02-15 |
| Effect of Pre-medication With Anti-inflammatory Drugs(Ibuprofen and Dexamethasone)on Post-Endodontic Pain (NCT06980870) | Armed Forces Institute of Dentistry, Pakistan | 2025-02-15 |
| QL1706 Plus Chemotherapy With AG Regime as First-line Treatment of Advanced PDAC (NCT06750861) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-02-15 |
| A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD) (NCT06144749) | Hillhurst Biopharmaceuticals, Inc. | 2025-02-15 |
| Oral Iohexol in the Management of Chylous Ascites After After Retroperitoneal or Extended Lymphadenectomy (NCT06820320) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2025-02-15 |
| The Anabolic Effect of Testosterone on Pelvic Floor Muscles (NCT06111209) | Brigham and Women's Hospital | 2025-02-15 |
| The Efficacy and Safety of Narlumosbart in Combination With Stereotactic Body Radiation Therapy to Improve the Efficacy of First-line Chemotherapy Combined With Immunotherapy in Patients With Bone Metastases From Advanced Non-small Cell Lung Cancer (NCT06738160) | Fudan University | 2025-02-15 |
| Phase II Single Arm Trial of Low Dose Capecitabine in Patients With Advanced Breast Cancer (NCT06105684) | University of Alabama at Birmingham | 2025-02-14 |
| Classroom Break, Cognition, and Fitness in Elementary School Children (NCT06258941) | Purdue University | 2025-02-14 |
| Phase II Study of Asciminib for Second-line Treatment of Chronic Phase Chronic Myeloid Leukemia (NCT06629584) | M.D. Anderson Cancer Center | 2025-02-14 |
| Nanobody-Based Anti-CD5 CAR-T for Relapsed/Refractory T-ALL/NHL (NCT06874946) | Peking University People's Hospital | 2025-02-14 |
| EXCLAIM: Exploring Combined Local and Systemic Approaches In Brain Metastasis: a Multi-cohort Randomized Phase II Study Evaluating Initial Response to Systemic Therapy and Subsequent Integration of Stereotactic Radiosurgery in Patients With Low-risk Brain Metastases and Central Nervous System-active (NCT06649058) | M.D. Anderson Cancer Center | 2025-02-14 |
| Study of Tebentafusp and Radioembolization in the Treatment of Metastatic Uveal Melanoma (NCT06627244) | University of Miami | 2025-02-14 |
| A Study of Abemaciclib and Cabozantinib in People With Clear Cell Renal Cell Carcinoma (ccRCC) (NCT06835972) | Memorial Sloan Kettering Cancer Center | 2025-02-14 |
| RHPRG4 FOR THE TREATMENT OF OCULAR GRAFT-VERSUS-HOST DISEASE (OGVHD) (NCT06495307) | Lubris Bio Pty Ltd | 2025-02-14 |
| Efficacy Study of EVO301 in Moderate to Severe Atopic Dermatitis (NCT06723405) | Evommune, Inc. | 2025-02-13 |
| Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema Advancing to Eventual Fibrosis: an Interventional Registry-embedded Bayesian Randomized Trial for Radiation Sequelae (STOP4-LATE-FIBROSE) (NCT06494111) | M.D. Anderson Cancer Center | 2025-02-13 |
| A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2) (NCT06760819) | Bayer | 2025-02-13 |
| The Efficacy of Topical Formulation Containing Ciplukan (Physalis Angulata Linn.) on Psoriasis Vulgaris Lesions (NCT06887322) | Universitas Padjadjaran | 2025-02-13 |
| A Trial of SHR0302Base in Patients With Vitiligo (NCT06790862) | Jiangsu HengRui Medicine Co., Ltd. | 2025-02-13 |
| A Bundled Intervention (NCT06593093) | University of Alabama at Birmingham | 2025-02-13 |
| Trial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients With Metastatic Prostate Cancer (NCT06616597) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2025-02-13 |
| A Study of ONO-1110 in Patients With Postherpetic Neuralgia (NCT06708416) | Ono Pharmaceutical Co., Ltd. | 2025-02-12 |
| Clinical Study of a Novel Oncolytic Virus Ad-TD-nsIL12 in the Treatment of Primary High-grade Glioma (NCT07126990) | Xiaorong Wu | 2025-02-12 |
| Leniolisib for Immune Dysregulation in CVID (NCT06897358) | Pharming Technologies B.V. | 2025-02-12 |
| Reverse HER2-negative Immune Resistant Breast Cancer (NCT06731140) | Fudan University | 2025-02-12 |
| Evaluating an Intervention for Physician Burnout (NCT06969950) | Brown University | 2025-02-12 |
| A Study of BMS-986490 With or Without Bevacizumab in Advanced Solid Tumors (NCT06730750) | Bristol-Myers Squibb | 2025-02-12 |
| Impact of NANO-PSO on Cognition in Older Adults with Mild to Moderate Cognitive Impairment (NCT06520878) | Distribuidora Biolife SA de CV | 2025-02-12 |
| Study of CART Cell (MB-CART19.1) in Patients With Relapsed or Refractory CD19 Positive NHL (NCT07271121) | King Hussein Cancer Center | 2025-02-12 |
| Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia (NCT06842745) | University of Pennsylvania | 2025-02-11 |
| Continuous Positive Airway Pressure (CPAP) Assisted Radiotherapy in Breast Cancer (NCT07373782) | Universitaire Ziekenhuizen KU Leuven | 2025-02-11 |
| Reduced CT + Anti-PD-1 as First Line Tx in Vulnerable Older Adults w/Adv <50% PD-L1 Non-Small Cell Lung Cancer (NSCLC) (NCT06731413) | Virginia Commonwealth University | 2025-02-11 |
| A Study to Evaluate the Efficacy and Safety of Orally Administered VX-01 (NCT06770933) | Vantage Biosciences Ltd | 2025-02-11 |
| A Phase I Clinical Study of ER2001 Injection for the Treatment of Early Manifest Huntington's Disease. (NCT07339514) | ExoRNA Bioscience | 2025-02-11 |
| Preoperative Tranexamic Acid (TXA) to Prevent Bleeding in Patients Undergoing Major Colorectal Surgery (NCT06657924) | Kristen Ban | 2025-02-11 |
| "Thymalfasin Immunotherapy Study with Triple Regimen in Advanced MSS/pMMR Colorectal Cancer" (NCT06829355) | Beijing Friendship Hospital | 2025-02-11 |
| A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1) (NCT06942572) | Splice Bio | 2025-02-11 |
| Effectiveness of MMS Compared With IFS Among Pregnant Women in Bangladesh: an Experimental Study (NCT07540130) | National Institute of Neurosciences and Hospital, Dhaka | 2025-02-11 |
| Study on the Safety, Tolerability, and Preliminary Efficacy of 161Tb-NYM032 in Patients with Metastatic Castration-Resistant Prostate Cancer (NCT06827080) | Zhengguo Chen | 2025-02-11 |
| A Study of Cemiplimab and Fianlimab in People With Clear Cell Renal Cell Carcinoma (NCT06699602) | Memorial Sloan Kettering Cancer Center | 2025-02-11 |
| Accelerated Brachytherapy Forward Chemo Radiation Therapy (ABC-RT) for Locally-advanced Cervical Cancer (NCT06529809) | Washington University School of Medicine | 2025-02-11 |
| Neoadjuvant Short-Course Radiotherapy With or Without Chemotherapy and AK112 in Locally Advanced Rectal Cancer (NCT06718543) | fan li | 2025-02-10 |
| A Dose Finding Study With an Anti-TSLP Antibody (GSK5784283) in Adults Aged 18 to 75 Years of Age With Uncontrolled Asthma (NCT06748053) | GlaxoSmithKline | 2025-02-10 |
| Intralesional Injection of Metronidazole for the Management of Cutaneous Leishmaniasis (NCT06798415) | Hayder Adnan Fawzi | 2025-02-10 |
| Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial (NCT06818331) | The Third Affiliated hospital of Zhejiang Chinese Medical University | 2025-02-10 |
| Efficacy and Safety Study of Disitamab Vedotin + RC148 vs. Albumin-Paclitaxone ± Toripalimab in HR-/HER2-low Breast Cancer (NCT06642545) | RemeGen Co., Ltd. | 2025-02-10 |
| A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1 (NCT06541847) | Healx Limited | 2025-02-10 |
| The Effectiveness of Intracuff Dexmedetomidine in Preventing Postoperative Sore Throat Following Prone Surgery (NCT07202624) | Prince Sultan Military Medical City | 2025-02-10 |
| A Study to Learn About How the Flu and COVID-19 Vaccines Act in Healthy People (NCT06821061) | BioNTech SE | 2025-02-10 |
| Phase II Multi-centered Study of Perioperative Ivonescimab Versus Pembrolizumab Combined with Standard of Care (SOC) in Patients with Resectable, Locally Advanced Head and Neck Squamous Cell Carcinoma (NCT06814067) | Fudan University | 2025-02-10 |
| MDMA-assisted Cognitive Processing Therapy Versus Cognitive Processing Therapy for Veterans With Severe Posttraumatic Stress Disorder (NCT05837845) | Patricia Suppes | 2025-02-10 |
| HRS-4642 Combined With Nimotuzumab in the Treatment of Recurrent or Metastatic Pancreatic Ductal Adenocarcinoma (NCT06773130) | West China Hospital | 2025-02-10 |
| Intravenous Ketamine for Treatment-Resistant Depression (NCT06668571) | Mayo Clinic | 2025-02-10 |
| The "What Is Important to Us" Communication Intervention Pilot Clinical Trial (NCT06208332) | Seattle Children's Hospital | 2025-02-10 |
| The Impact of Vericiguat on Microvascular Function in Patients With Documented Vasospastic Angina Pectoris (NCT06415227) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2025-02-10 |
| Efficacy and Safety of Continuous Infusion of Terlipressin vs Bolus Terlipressin in ACLF Patients With Acute Esophageal Variceal Bleed (NCT06815770) | Institute of Liver and Biliary Sciences, India | 2025-02-10 |
| Zinc for Infection Prevention in Sickle Cell Anemia-2 (ZIPS-2) (NCT06561061) | Indiana University | 2025-02-10 |
| A Study Evaluating the Effect of Inhaled PT007(AS MDI) Versus Placebo MDI and Ventolin Evohaler on Lung Function in Adult Participants With Asthma (NCT06644924) | AstraZeneca | 2025-02-10 |
| A Dose-Response Controlled Trial of Bevifibatide for Acute Ischemic Stroke (NCT06712004) | Zhujiang Hospital | 2025-02-10 |
| 177Lu-PSMA (177Lu-PNT2002) in PSMA-Positive Adenoid Cystic Carcinoma (NCT06322576) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2025-02-10 |
| Tagraxofusp and Low-Intensity Chemotherapy for CD123-Positive Relapsed or Refractory AML (NCT06561152) | Stanford University | 2025-02-10 |
| SBRT Plus Lenalidomide for Solitary Plasmacytoma: Phase II Trial (NCT06863584) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-02-10 |
| Intralesional Injection of Levofloxacin for the Management of Cutaneous Leishmaniasis (NCT06797544) | Hayder Adnan Fawzi | 2025-02-09 |
| Human Growth Hormone Injections in the Knee Joint to Treat Osteoarthritis (NCT06354023) | John Sledge | 2025-02-08 |
| Axicabtagene Ciloleucel Injection in Patients With Relapsed/Refractory Follicular Lymphoma (NCT06826118) | The First Affiliated Hospital of Xiamen University | 2025-02-08 |