| RECTIFY-1: Neoadjuvant Botensilimab + Balstilimab in MSS/pMMR Early Rectal Cancer (NCT07735624) | Dana-Farber Cancer Institute | 2026-09-01 |
| Cannabis Gummy for the Improvement of Sleep and Quality of Life in Patients With Cancer, Pillow Trial (NCT07658677) | Theodore Brasky PhD | 2026-09-01 |
| Optimized, Neuroplasticity-Enhanced-Depression (ONE-D) Transcranial Magnetic Stimulation (TMS) Treatment for Female Athletes With Co-morbid Depression and Concussion (NCT07507214) | University of Florida | 2026-09-01 |
| Pembrolizumab and Lenvatinib in Mismatch Repair Proficient Recurrent Endometrial Cancer After Failure of First-Line Therapy With Platinum-based Doublet and Immunotherapy (NCT07594015) | University of Miami | 2026-09-01 |
| The Effect of L-Carnitine on Wound Healing in Patients With Diabetic Foot Ulcer. (NCT07768228) | Ain Shams University | 2026-09-01 |
| Pacritinib With Aza for Upfront Myelodysplastic Syndrome (NCT07387354) | Thomas Jefferson University | 2026-09-01 |
| A Study Of Synthetic THC And Sleep (NCT07570953) | Mayo Clinic | 2026-09-01 |
| A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A (NCT07226206) | Hoffmann-La Roche | 2026-09-01 |
| Low-Dose Naltrexone For ME/CFS: Dose-Finding (NCT07285473) | University of Alabama at Birmingham | 2026-09-01 |
| Exploratory Study Evaluating the Relevance of [68Ga]Ga-FAPI-46 for Staging and Identifying Progressing Patients With Transthyretin Cardiac Amyloidosis (NCT07549841) | Nantes University Hospital | 2026-09-01 |
| The Acute Effects of Psilocybin on Cognition, Memory, and Brain Function (NCT07079852) | Manoj Doss | 2026-09-01 |
| Olaparib in the Treatment of BRCA1/2 Unmutated and BRCA1 Promoter Methylated Recurrent and Metastatic Triple-negative Breast Cancer (NCT05522491) | Hebei Medical University Fourth Hospital | 2026-09-01 |
| MOTIF@FRESH: Modifying Organisms Transvaginally in Females @ FRESH (NCT07566754) | Douglas Kwon | 2026-09-01 |
| Consolidative Therapy After EV + Pembrolizumab in Muscle Invasive Bladder Cancer, REINFORCE Trial (NCT07579195) | University of Washington | 2026-09-01 |
| Little Lungs Study (NCT06855043) | University of Wisconsin, Madison | 2026-09-01 |
| Study to Evaluate the Safety and Efficacy of Humacyte's Coronary Tissue Engineered Vessel (CTEV) in Patients With Coronary Artery Disease Requiring Coronary Artery Bypass Grafting (CABG) (NCT07730528) | Humacyte, Inc. | 2026-09-01 |
| SCALp Cooling for pReventing aLopecia With nEw anTibody-drug Conjugates (NCT07474558) | Jules Bordet Institute | 2026-09-01 |
| Study on Doses of Inhaled ALX1 in Adults With Bronchiectasis (NCT07731919) | Vast Therapeutics | 2026-09-01 |
| Evaluation of the Safety and Efficacy of LB-DTK-BKV in Patients With BK Virus-Associated Hemorrhagic Cystitis Following Allogeneic Hematopoietic Stem Cell Transplantation (NCT07638332) | LucasBio | 2026-09-01 |
| Terazosin And Metabolic Engagement in Parkinson's Disease (NCT07288450) | Nandakumar Narayanan | 2026-09-01 |
| Frontline Risk-Adapted Optimization of Novel Targeted Immunotherapy Evaluation in High-Risk MCL (NCT07569965) | Miltenyi Biomedicine GmbH | 2026-09-01 |
| Trial of Varenicline With Nicotine Lozenges and a Smartphone Medication Adherence Intervention for Smoking Cessation (NCT07099638) | University of Oklahoma | 2026-09-01 |
| Use of Gocovri to Improve Disability Due to Radiation Encephalopathy (NCT07125222) | Weill Medical College of Cornell University | 2026-09-01 |
| Pilot Study: Effects of Nimodipine on Alcohol Drinking (NCT06900998) | Yale University | 2026-09-01 |
| Mesenchymal Stem Cells With Cooling Therapy for Infants With Hypoxic-Ischemic Encephalopathy (NCT07018739) | Mahidol University | 2026-09-01 |
| A Study of Lifileucel (Tumor-infiltrating Lymphocytes) in Adults With Advanced Soft Tissue Sarcoma (NCT07741877) | Iovance Biotherapeutics, Inc. | 2026-09-01 |
| Timing of Empagliflozin in Primary PCI: Pre-Reperfusion Versus Post-Reperfusion Versus Placebo in South Asian STEMI Patients (NCT07749014) | Rehman Medical Institute - RMI | 2026-09-01 |
| The Combined Role of FAPI PET and Liquid Biopsy in the Staging and Clinical Management of Bladder Cancer - FUTURE Trial (NCT07257718) | Chiti Arturo | 2026-09-01 |
| Self-Amplifying mRNA COVID-19 Vaccine (LUNAR-COV19) Versus Comirnaty Vaccine in Adult Hematopoietic Cell Transplant Patients (NCT07390968) | Fred Hutchinson Cancer Center | 2026-09-01 |
| Allopregnanolone in Chronic Complex Traumatic Brain Injury (NCT04003285) | VA Office of Research and Development | 2026-09-01 |
| Overcoming Resistance to Immunotherapy Combining Gemcitabine With Ivonescimab in Advanced NSCLC (NCT07158489) | Swiss Cancer Institute | 2026-09-01 |
| Hotspot Stereotactic Ablative Radiotherapy Versus Traditional Stereotactic Ablative Radiotherapy for the Treatment of Early-Stage Non-Small Cell Lung Cancer (NCT07718672) | Roswell Park Cancer Institute | 2026-09-01 |
| In Vivo Fluorescence Molecular Bronchoscopy of Durvalumab-680LT in Patients With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) After Chemoradiotherapy (NCT07653438) | University Medical Center Groningen | 2026-09-01 |
| Radscopal Radiotherapy Plus Immunotherapy for Chemotherapy-Ineligible Patients With Newly Diagnosed Metastatic Nasopharyngeal Cancer: A Single-Center, Open-Label, Phase II Study (NCT07756190) | Sun Yat-sen University | 2026-09-01 |
| Study Evaluating a Gene Therapy for IPEX Syndrome Through the Expression of FOXP3 on Deficient T Cells to Produce Tregs-like. (NCT07697118) | Assistance Publique - Hôpitaux de Paris | 2026-09-01 |
| Safety Study for the Use of Rapamycin in Children With Familial Adenomatous Polyposis (NCT06308445) | University Hospital, Toulouse | 2026-09-01 |
| Visual Instillation of Sphenopalatine-block Intervention for ONgoing Migraine (NCT07764783) | Association of Migraine Disorders | 2026-09-01 |
| First in Human Study of BETA-TT8 in wetAge-related Macular Degeneration (wetAMD) (NCT07766473) | Filamon LTD | 2026-09-01 |
| Ivermectin Combined With Immune Checkpoint Inhibition in Cancer (ICONIC) (NCT07487805) | University of Florida | 2026-09-01 |
| GELAD-Based Response-Adapted Treatment for Early-Stage Extranodal NK/T-Cell Lymphoma (NCT07768943) | Fudan University | 2026-09-01 |
| IGFBP-2 Vaccine to Prevent Ovarian Cancer Progression in Patients With Serologic Detection of Recurrence (NCT07495124) | University of Washington | 2026-09-01 |
| Effect of an Isolevuglandin Scavenger on Salt Sensitivity of Blood Pressure and Immune Cell Activation in Humans (NCT07602166) | Vanderbilt University Medical Center | 2026-09-01 |
| Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (NCT07729137) | Emmecell | 2026-09-01 |
| Pregnenolone for Cannabis Use Disorder and Depression (NCT07685964) | University of Texas Southwestern Medical Center | 2026-09-01 |
| CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO) (NCT06972108) | University of Alberta | 2026-09-01 |
| The Safety and Efficacy of Roflumilast Foam in HS (NCT07263230) | Beth Israel Deaconess Medical Center | 2026-09-01 |
| Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma (NCT07059611) | Abramson Cancer Center at Penn Medicine | 2026-09-01 |
| Gilteritinib-Azacitidine-Venetoclax Combination Therapy in Patients With Relapsed/Refractory Leukemia (NCT07755202) | Florian Kuchenbauer | 2026-09-01 |
| A Phase 2 Trial Of The Bruton Tyrosine Kinase Degrader BGB-16673 In Combination With BCL-2 Inhibitor Sonrotoclax For Patients With Treatment-Naive Chronic Lymphocytic Leukemia (CLL) (NCT07508995) | M.D. Anderson Cancer Center | 2026-09-01 |
| Evaluation of Antibiotic Prophylaxis in Myelodysplastic Syndromes and Acute Myeloid Leukemia (MYELO-CAN:ABX) (NCT07528417) | University of Manitoba | 2026-09-01 |
| Influence of Lung Volume Optimization Maneuver on Cardiac Output and Lung Compliance in Ventilated Children With Congenital Heart Disease Undergoing Surgical Repair (NCT07486167) | Charite University, Berlin, Germany | 2026-09-01 |
| Pre-hepatectomy Rehabilitation in Obese MASLD-Complicated Living Liver Donors With Mazdutide (PRIME) (NCT07718126) | West China Hospital | 2026-09-01 |
| Nemtabrutinib and Venetoclax for the Treatment of Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT07557056) | Jennifer Woyach | 2026-09-01 |
| A Phase II Study of SSGJ-612 Plus a HER2-Targeted ADC in HR-Positive, HER2-Low or HER2-Ultralow Expression Metastatic Breast Cancer (NCT07757230) | Shenyang Sunshine Pharmaceutical Co., LTD. | 2026-09-01 |
| Salvage Chemotherapy With Sonrotoclax, Cladribine, and Standard-dose Cytarabine, Sequentially Followed by HSCT for R/R AML. (NCT07757672) | Institute of Hematology & Blood Diseases Hospital, China | 2026-09-01 |
| Evaluating the Use of Oral Indapamide to Reduce Disabiltiy Progression in Progressive Multiple Sclerosis (MS) (NCT07765212) | Eva M.M. Strijbis | 2026-09-01 |
| Severe Hepatitis Intervention With Emapalumab for Liver Disease (NCT07744919) | Children's Healthcare of Atlanta | 2026-09-01 |
| A Precision Medicine Trial for Patients With Relapsed or Refractory T Cell ALL (NCT07522801) | Philippe ROUSSELOT | 2026-09-01 |
| Partial Cystectomy & Extended Pelvic Lymph Node Dissection With SOC Perioperative Systemic Therapy (NCT06290687) | Case Comprehensive Cancer Center | 2026-09-01 |
| A Study of Velzatinib in Participants With Metastatic and/or Unresectable GIST After Imatinib, Sunitinib, Regorafenib, and Pimitespib (NCT07689201) | GlaxoSmithKline | 2026-08-31 |
| Y-6 Sublingual Tablets for Acute Penetrating Artery Infarction (NCT07721545) | Neurodawn Pharmaceutical Co., Ltd. | 2026-08-31 |
| Evaluate the Efficacy and Safety of VV913 Capsules in the Treatment of PE (NCT07722780) | Vigonvita Life Sciences | 2026-08-31 |
| Sacituzumab Tirumotecan in Pts w/ NEPC After Progression on Prior Chemotherapy (NCT07639086) | Virginia Commonwealth University | 2026-08-31 |
| Assessing of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies (NCT07745569) | University of New Mexico | 2026-08-31 |
| A Study to Test How Well BAY 3670549 Works and How Safe it is in Patients With Atrial Fibrillation (NCT07625215) | Bayer | 2026-08-31 |
| A Study Exploring the Effect of Adjuvanted RZV or RSVPreF3 Vaccines on Coronary Plaque Progression in Adults >=50 Years of Age at Risk for Cardiovascular Events (NCT07712380) | GlaxoSmithKline | 2026-08-31 |
| Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas (NCT07620548) | Washington University School of Medicine | 2026-08-31 |
| The CARDIOPROTECT Trial (NCT07654426) | Beth Israel Deaconess Medical Center | 2026-08-31 |
| Study of Zola-cel (BMS-986353), in Participants With Autoimmune Cytopenia (Breakfree-AiCE) (NCT07603557) | Juno Therapeutics, Inc., a Bristol-Myers Squibb Company | 2026-08-31 |
| Combining Neo-adjuvant ATR-inhibition With Nodal SBRT for Early-stage Resectable HPV+ OPSCCs (NCT07578467) | Abramson Cancer Center at Penn Medicine | 2026-08-31 |
| Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard of Care CAR-T Cell Therapy (NCT07341191) | Canadian Cancer Trials Group | 2026-08-31 |
| Sacituzumab Tirumotecan (Sac-TMT/SKB264) Plus Tagitanlimab (KL-A167) in Patients With Recurrent or Metastatic Esophageal Squamous Cell Carcinoma and Gastric/Gastroesophageal Junction Adenocarcinoma (NCT07701681) | Sun Yat-sen University | 2026-08-31 |
| A Study of Sotatercept (MK-7962) in Japanese Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-032) (NCT07646860) | Merck Sharp & Dohme LLC | 2026-08-31 |
| A Phase 2 Study of ABSK043 Combined With Osimertinib (NCT07710612) | Abbisko Therapeutics Co, Ltd | 2026-08-31 |
| A Study About the Safety of ASP2767 and Whether it Helps People With Glaucoma-Related Optic Nerve Damage (NCT07770685) | Astellas Pharma Global Development, Inc. | 2026-08-31 |
| A Clinical Study of SYS6041 Combination Therapy for Recurrent Ovarian Cancer (NCT07714668) | CSPC Megalith Biopharmaceutical Co.,Ltd. | 2026-08-31 |
| A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD) (NCT07636811) | Alnylam Pharmaceuticals | 2026-08-31 |
| Testing Ivonescimab in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancers Without Liver Metastases (NCT07359456) | UNICANCER | 2026-08-31 |
| A Clinical Trial Evaluating Fecal Microbiota Transplantation (FMT) in Adolescents With ADHD (NCT07756255) | University of Calgary | 2026-08-31 |
| PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma (NCT06639607) | Washington University School of Medicine | 2026-08-31 |
| Mammogram Pretreatment With Ulipristal Acetate (NCT07434128) | OHSU Knight Cancer Institute | 2026-08-31 |
| A Safety and Efficacy Study of Combined Fianlimab + Cemiplimab in Children and Young Adults With Recurrent or Progressive High-Grade Glioma or Posterior Fossa-A Ependymoma (NCT07567469) | Regeneron Pharmaceuticals | 2026-08-31 |
| An Extension Study of S-606001 in Participants With Late-onset Pompe Disease (LOPD) (NCT07750990) | Shionogi | 2026-08-31 |
| A Prospective, Exploratory Study of Becotatug Vedotin Plus Putlimab for Neoadjuvant Therapy and Adjuvant Radiotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma (NCT07707167) | Jiangsu Cancer Institute & Hospital | 2026-08-31 |
| Tovecimig Plus FOLFIRI in Second Line Metastatic Colorectal Cancer (NCT07662031) | Washington University School of Medicine | 2026-08-31 |
| CCR2 PET Imaging Head and Neck Squamous Cell Carcinoma (NCT07659678) | Washington University School of Medicine | 2026-08-31 |
| A Study Investigating Alternate Schedules of Tislelizumab Plus Chemotherapy in Japanese Patients With First-line Advanced ESCC (NCT07733180) | BeOne Medicines | 2026-08-31 |
| Trastuzumab Deruxtecan and Lovastatin in HER2-low and Ultralow Advanced or Metastatic Breast Cancer (NCT07619365) | Washington University School of Medicine | 2026-08-31 |
| A Phase II Study to Evaluate the Efficacy of UF-KURE19 Cells in Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas (NCT07713459) | Kure Cells, INC | 2026-08-31 |
| Trial of Revumenib Plus FLA Chemotherapy for Children With Relapsed or Refractory NUP98-rearranged AML." (NCT07686107) | Therapeutic Advances in Childhood Leukemia Consortium | 2026-08-31 |
| A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Inebilizumab in Children With Generalized Myasthenia Gravis (gMG) (NCT06987539) | Amgen | 2026-08-31 |
| NIMBLE-CRC: NeoImmunoModulation Before Leveraging Excision in Colorectal Rectal Cancer (NCT07677579) | Northwell Health | 2026-08-30 |
| A Phase I/II Study of FG-M131 in TRBC1+ Relapsed/Refractory Peripheral T-Cell Lymphoma (NCT07758491) | FutureGen Biopharmaceutical (Beijing) Co., Ltd | 2026-08-30 |
| Isotretinoin vs. Doxycycline for Acneiform Rash in Patients Receiving Drugs That Target the MAPK Pathway (NCT07629167) | University of California, San Francisco | 2026-08-30 |
| A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC (NCT07459634) | Jazz Pharmaceuticals | 2026-08-30 |
| Phase II/III Randomized Trial of UC-MSC Secretome vs Sodium Hyaluronate in Knee Osteoarthritis (NCT07337863) | Universitas Sriwijaya | 2026-08-30 |
| A Study to Evaluate the Efficacy and Safety of DA-302168S Tablets in Subjects With Type 2 Diabetes (NCT07755150) | Chendu DIAO Pharmaceutical Group CO., LTD. | 2026-08-30 |
| Fostamatinib for Treating Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Adults (NCT06564207) | Inova Health Care Services | 2026-08-30 |
| A Phase Ib/II Study of SYS6090 Combination Therapy in Advanced Colorectal Cancer (NCT07750041) | CSPC Megalith Biopharmaceutical Co.,Ltd. | 2026-08-30 |
| Conversion Therapy With Retlirafusp Alfa Plus Chemotherapy in Gastric or Gastroesophageal Junction Adenocarcinoma (NCT07709767) | Tang-Du Hospital | 2026-08-30 |