| Safety, Pharmacokinetics, and Pharmacodynamics/Efficacy of SBC-103 in Mucopolysaccharidosis III, Type B (MPS IIIB) (NCT02324049) | Alexion Pharmaceuticals, Inc. | 2015-01-22 |
| A Pilot Study of "OncozeneTM" Microspheres for Intra-arterial Delivery of Doxorubicin (NCT02141906) | University of Texas Southwestern Medical Center | 2015-01-21 |
| Bevacizumab Against Recurrent Retinal Detachment (NCT02192970) | University of Wisconsin, Madison | 2015-01-21 |
| Pasireotide in Prevention of GI Toxicity (NCT02215070) | Anthony Sung, MD | 2015-01-21 |
| A Study Evaluating Chemotherapy With Fractionated Cisplatin/Gemcitabine Versus Carboplatin/Gemcitabine in the Treatment of Advanced or Metastatic Urothelial Cancer With Impaired Renal Function. (NCT02240017) | Institut Claudius Regaud | 2015-01-21 |
| T-cell Depleted Hematopoietic Stem Cell Boosts Without Conditioning for Poor Marrow Graft Function Following Allogeneic Hematopoietic Stem Cell Transplantation (NCT02350777) | Memorial Sloan Kettering Cancer Center | 2015-01-21 |
| Phase II Study of Pembrolizumab After Curative Intent Treatment for Oligometastatic Non-Small Cell Lung Cancer (NCT02316002) | Abramson Cancer Center at Penn Medicine | 2015-01-21 |
| BI 409306 in Patients With Cognitive Impairment Due to Alzheimer's Disease. (NCT02337907) | Boehringer Ingelheim | 2015-01-21 |
| A Study of Granix to Disrupt the Bone Marrow Microenvironment in Patients With Multiple Myeloma Undergoing Autologous Transplantation (NCT02112045) | Washington University School of Medicine | 2015-01-20 |
| Evaluate the Mediators of Sensitivity and Resistance to Nivolumab Plus Ipilimumab in Patients With Advanced NSCLCs (NCT02350764) | Memorial Sloan Kettering Cancer Center | 2015-01-20 |
| PANGEA-IMBBP: Personalized Antibodies for Gastro-Esophageal Adenocarcinoma - A 1st Pilot Metastatic Trial of Biologics Beyond Progression (NCT02213289) | University of Chicago | 2015-01-20 |
| A Phase II, Open Label, Multiple Arm Study of AUY922, BYL719, INC280, LDK378 and MEK162 in Chinese Patients With Advanced Non-small Cell Lung Cancer (NCT02276027) | Novartis Pharmaceuticals | 2015-01-20 |
| Study To Evaluate Emtricitabine/Tenofovir Alafenamide (F/TAF) in Human Immunodeficiency Virus 1 (HIV-1) Infected Children and Adolescents Virologically Suppressed on a 2-Nucleoside/Nucleotide Reverse Transcriptase Inhibitor (2-NRTI)-Containing Regimen (NCT02285114) | Gilead Sciences | 2015-01-20 |
| Phase II Study of IRD (Ixazomib, Lenalidomide, Dexamethasone) Post Autologous Stem Cell Transplantation Followed by Maintenance Ixazomib or Lenalidomide for Multiple Myeloma (NCT02253316) | Washington University School of Medicine | 2015-01-20 |
| Partnership for Research on Ebola Vaccines in Liberia (PREVAIL) (NCT02344407) | National Institute of Allergy and Infectious Diseases (NIAID) | 2015-01-20 |
| A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) in BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, and Metastatic Castrate-Resistant Prostate Cancer (NCT02203513) | National Cancer Institute (NCI) | 2015-01-20 |
| Evaluation of Oncoxin-Viusid® in Head and Neck Cancer (NCT03541772) | Catalysis SL | 2015-01-20 |
| Dose-Ranging Study of the Bimatoprost Ocular Insert (NCT02358369) | ForSight Vision5, Inc. | 2015-01-19 |
| Randomized Study on Postmenopausal Women With Early Stage Breast Cancer: WBI Versus APBI (NCT02375048) | Istituto Clinico Humanitas | 2015-01-19 |
| Concurrent Chemotherapy and Radiation Therapy for Newly Diagnosed Nasal NK Cell Lymphoma (NCT02106988) | M.D. Anderson Cancer Center | 2015-01-16 |
| Sequential Regimen of Bendamustin [B] Followed by GA101 and Ibrutinib [I] in CLL Patients (NCT02345863) | German CLL Study Group | 2015-01-16 |
| Efficacy and Safety of Riociguat in Patients With Systemic Sclerosis (NCT02283762) | Bayer | 2015-01-15 |
| EINSTEIN Junior Phase II: Oral Rivaroxaban in Young Children With Venous Thrombosis (NCT02309411) | Bayer | 2015-01-15 |
| Alzheimer Disease Proof of Concept Study With BI 409306 Versus Placebo (NCT02240693) | Boehringer Ingelheim | 2015-01-15 |
| Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations (NCT02124772) | Novartis Pharmaceuticals | 2015-01-15 |
| A Phase 2 Study to Evaluate the Impact of MTP-131 (Bendavia™) on Skeletal Muscle Function in Elderly (NCT02245620) | Stealth BioTherapeutics Inc. | 2015-01-15 |
| HYPOCHLOROUS ACID SUBSTANTIVITY AS ANTIPLAQUE AGENT (HOCl-SAP) (NCT03174756) | Universidad El Bosque, Bogotá | 2015-01-15 |
| Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene Mutations (NCT02341807) | Spark Therapeutics, Inc. | 2015-01-15 |
| Dose Adjusted EPOCH Regimen in Combination With Ofatumumab or Rituximab in Treating Patients With Newly Diagnosed or Relapsed or Refractory Burkitt Lymphoma or Relapsed or Refractory Acute Lymphoblastic Leukemia (NCT02199184) | M.D. Anderson Cancer Center | 2015-01-14 |
| Study of AZD1775 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring TP53 Mutation as a Second-line Chemotherapy (NCT02448329) | Samsung Medical Center | 2015-01-14 |
| Vaccination of High Risk Breast Cancer Patients (NCT02229084) | University of Arkansas | 2015-01-14 |
| Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy (RCD) and Enhanced S-Cone Syndrome (ESCS) (NCT02338973) | National Eye Institute (NEI) | 2015-01-14 |
| A Study of MHAA4549A in Combination With Oseltamivir Versus Oseltamivir in Participants With Severe Influenza A Infection (NCT02293863) | Genentech, Inc. | 2015-01-14 |
| Study of Safety and Efficacy of EGFR-TKI EGF816 in Combination With cMET Inhibitor INC280 in Adult Patients With EGFR Mutated Non Small Cell Lung Cancer. (NCT02335944) | Novartis Pharmaceuticals | 2015-01-13 |
| Phase I/II Study of SRP-4053 in DMD Patients (NCT02310906) | Sarepta Therapeutics, Inc. | 2015-01-13 |
| Acupuncture for Pain Control After Elective Caesarean Section (NCT02364167) | University Medicine Greifswald | 2015-01-13 |
| First-line Metastatic Pancreatic Cancer : FOLFIRINOX +/- LV5FU2 in Maintenance Versus Firgem (NCT02352337) | Federation Francophone de Cancerologie Digestive | 2015-01-12 |
| Gemcitabine, Trastuzumab, and Pertuzumab in the Treatment of Metastatic HER2-Positive Breast Cancer After Prior Trastuzumab/Pertuzumab, or Pertuzumab Based Therapy (NCT02252887) | Memorial Sloan Kettering Cancer Center | 2015-01-12 |
| A Study to Evaluate ASP8232 in Reducing Central Retinal Thickness in Subjects With Diabetic Macular Edema (DME) (NCT02302079) | Astellas Pharma Europe B.V. | 2015-01-12 |
| A Phase 2 Clinical Study in Subjects With Primary Progressive Multiple Sclerosis to Assess the Efficacy, Safety and Tolerability of Two Oral Doses of Laquinimod Either of 0.6 mg/Day or 1.5mg/Day (Experimental Drug) as Compared to Placebo (NCT02284568) | Teva Branded Pharmaceutical Products R&D, Inc. | 2015-01-12 |
| Ibrutinib After Intensive Induction in Treating Patients With Previously Untreated Mantle Cell Lymphoma (NCT02242097) | Northwestern University | 2015-01-12 |
| Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL (NCT02337829) | Acerta Pharma BV | 2015-01-12 |
| Ruxolitinib and Pracinostat Combination Therapy for Patients With Myelofibrosis (MF) (NCT02267278) | M.D. Anderson Cancer Center | 2015-01-12 |
| Safety and Immunogenicity of a 10 Valent Pneumococcal Conjugate Vaccine (SIILPCV10) in Healthy Adults, Toddlers, Infants (NCT02308540) | PATH | 2015-01-12 |
| A Multi-Center Study of Lapatinib in Patients With Trastuzumab-refractory Metastatic Breast Cancer (NCT02362958) | Sun Yat-sen University | 2015-01-09 |
| Efficacy of IntraVenous ImmunoGlobulins in Toxic Shock Syndromes: a Paediatric Pilot Study (NCT02219165) | Hospices Civils de Lyon | 2015-01-08 |
| Controlled Level EVERolimus in Acute Coronary Syndromes (NCT01529554) | University of Zurich | 2015-01-08 |
| Long Term Extension Safety Study in Patients With Dementia of the Alzheimer's Type Who Completed Study CPC-001-07 (NCT02434666) | Chase Pharmaceuticals Corporation, an affiliate of Allergan plc | 2015-01-08 |
| Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5 (NCT02314208) | Institut National de la Santé Et de la Recherche Médicale, France | 2015-01-08 |
| Efficacy and Safety Study of Apremilast to Treat Active Ulcerative Colitis (NCT02289417) | Amgen | 2015-01-08 |
| Evaluation of Oncoxin-Viusid® in Cervical Cancer and Endometrial Adenocarcinoma. (NCT03540407) | Catalysis SL | 2015-01-07 |
| Study of AZD5363 in Combination With Paclitaxel, in Advanced Gastric Adenocarcinoma Patients Harboring PIK3CA Mutation and/or PIK3CA Amplification as a Second-line Chemotherapy (NCT02451956) | Samsung Medical Center | 2015-01-07 |
| Evaluate SAGE-547 in Female Participants With Severe Postpartum Depression (NCT02285504) | Supernus Pharmaceuticals, Inc. | 2015-01-07 |
| Feasibility Study for Fibroblast Autologous Skin Grafts (NCT01964859) | Johns Hopkins University | 2015-01-07 |
| Safety and Efficacy Study of Nab®-Paclitaxel With CC-486 or Nab®-Paclitaxel With Durvalumab, and Nab®-Paclitaxel Monotherapy as Second/Third-line Treatment for Advanced Non-small Cell Lung Cancer (NCT02250326) | Celgene | 2015-01-07 |
| Efficacy and Safety Study of GPX-150 to Treat Soft Tissue Sarcoma (NCT02267083) | Gem Pharmaceuticals | 2015-01-07 |
| PH 2 ADI-PEG 20 Acute Myeloid Leukemia (NCT01910012) | Polaris Group | 2015-01-06 |
| Bronchial NIR Image-guided Resection (NCT03097575) | Massachusetts General Hospital | 2015-01-06 |
| Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients (NCT02257853) | National Institutes of Health Clinical Center (CC) | 2015-01-05 |
| A Study of Epacadostat (INCB024360) in Combination With Durvalumab (MEDI4736) in Subjects With Selected Advanced Solid Tumors (ECHO-203) (NCT02318277) | Incyte Corporation | 2015-01-05 |
| Combination Therapy With Carfilzomib, Romidepsin, Lenalidomide in Patients With Relapsed or Refractory B- and T-cell Lymphomas (NCT02341014) | Memorial Sloan Kettering Cancer Center | 2015-01-02 |
| GVAX Pancreas Vaccine (With CY) and CRS-207 With or Without Nivolumab (NCT02243371) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2015-01-02 |
| Effects of S-1 and Capecitabine on Coronary Artery Blood Flow (NCT02216149) | Heikki Joensuu | 2015-01-01 |
| L-dopa Versus Dopamine Agonists After Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease (NCT02347059) | University of Toronto | 2015-01-01 |
| Safety and Efficacy Study of Mix Vaccine in Prostate Carcinoma Patient (NCT02338700) | Fuda Cancer Hospital, Guangzhou | 2015-01-01 |
| Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO (NCT02303184) | Clearside Biomedical, Inc. | 2015-01-01 |
| An Observational Study to Evaluate the Efficacy of Biweekly Romiplostim in Adult Patients With ITP (NCT02338414) | Samsung Medical Center | 2015-01-01 |
| Ingenol Mebutate (Picato®) With Methyl Aminolevulinate Photodynamic Therapy for the Treatment of Actinic Keratosis (NCT02354391) | Pacific Dermaesthetics | 2015-01-01 |
| Phase IIa Study of the Product QGC001 Compared With Placebo in Patients With Essential Hypertension (NCT02322450) | Quantum Genomics SA | 2015-01-01 |
| Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy (NCT02559830) | Shenzhen Second People's Hospital | 2015-01-01 |
| Patient-Controlled Thoracic Paravertebral Block After Video-Assisted Thoracoscopic Surgery (NCT02237664) | Imam Abdulrahman Bin Faisal University | 2015-01-01 |
| Comparing the Antibacterial Effect of 810 nm Diode Laser and Photodynamic Therapy (NCT02555488) | Shahid Beheshti University | 2015-01-01 |
| The Efficacy and Safety of Apatinib in Heavily Pretreated Advanced Non-squamous Non-small Cell Lung Cancer (NCT02515435) | Tongji University | 2015-01-01 |
| Comparative Evaluation of Herbal and Allopathic Drugs for the Treatment of Chronic Diarrhea (NCT02642250) | Shifa Ul Mulk Memorial Hospital | 2015-01-01 |
| Prophylactic Intravesical Chemotherapy After Radical Nephroureterectomy for Upper Tract Urothelial Carcinoma: a Randomized Controlled Trial Between Single Postoperative Dose Versus Maintenance Therapy. (NCT02438865) | Mansoura University | 2015-01-01 |
| Icotinib for Completed Resected IB NSCLC With EGFR Mutation (NCT02264210) | Sun Yat-sen University | 2015-01-01 |
| The Safety and Efficacy of Administrating DiaPep277® Vaccination in Type 1 Diabetes Patients. (NCT01881958) | Hadassah Medical Organization | 2015-01-01 |
| Levetiracetam Versus Sodium Valproate in Children With Refractory Generalized Convulsive Status Epilepticus (NCT02920060) | Banaras Hindu University | 2015-01-01 |
| OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Dry Eye (NCT02468700) | Ocular Therapeutix, Inc. | 2015-01-01 |
| Exenatide for Stress Hyperglycemia (NCT01969149) | Centre Hospitalier Universitaire de Besancon | 2015-01-01 |
| Celution Prepared Adipose Derived Regenerative Cells in the Treatment of Osteoarthritis of the Knee (NCT02326961) | Cytori Therapeutics | 2015-01-01 |
| New Study - Humoral Response to Tick-borne Encephalitis Vaccine in Elderly (NCT02318069) | Sormland County Council, Sweden | 2015-01-01 |
| Methylphenidate Plus GWI-Nutrient Formula as a Treatment for Patients With Gulf War Illness (NCT02357030) | K-PAX Pharmaceuticals, Inc. | 2015-01-01 |
| A Study to Evaluate Efficacy and Safety of CS-3150 in Japanese Hypertensive Subjects (NCT02345044) | Daiichi Sankyo | 2015-01-01 |
| The Dutch STRIDER (Sildenafil TheRapy In Dismal Prognosis Early-onset Fetal Growth Restriction) (NCT02277132) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2015-01-01 |
| Clinical Intramuscular Gene Transfer of rAAV1.CMV.huFollistatin344 Trial to Patients With Duchenne Muscular Dystrophy (NCT02354781) | Jerry R. Mendell | 2015-01-01 |
| The Effect of Dairy and Non-dairy Alternatives on Satiety and Post-meal Glycemia in Healthy Young Adults (NCT02491814) | University of Toronto | 2015-01-01 |
| Use of Acellular Dermal in the Incarcerated Inguinal Hernia Tension-free Reconstructions (NCT02469142) | Xijing Hospital of Digestive Diseases | 2015-01-01 |
| Evaluation of the Suitability of PD P 506 A in the PDT of Distal Subungual Onychomycosis (DSO) of the Great Toenail. (NCT02355899) | photonamic GmbH & Co. KG | 2015-01-01 |
| Advanced Pelvic Floor Training Program for Prostate Cancer Surgery (NCT02233608) | University of Guelph-Humber | 2015-01-01 |
| Splenectomy as a Treatment for Patient With Relapsed Haemophagocytic Lymphohistiocytosis of Unknown Etiology (NCT02862054) | Beijing Friendship Hospital | 2015-01-01 |
| Optimal Timing of Misoprostol Administration Prior to Office Hysteroscopy (NCT02316301) | Cairo University | 2015-01-01 |
| Effect of Entacapone on Bodyweight Loss in Obese Population (NCT02349243) | Kaichun Wu | 2015-01-01 |
| A Study of Postsurgical Pain Control for Lower Extremity Fractures (NCT02214810) | Broward Health | 2015-01-01 |
| Phase IIB TL + YCWP + DC in Melanoma (NCT02301611) | Elios Therapeutics, LLC | 2015-01-01 |
| Topiramate Trial for Compulsive Buying (NCT02138058) | University of Sao Paulo | 2015-01-01 |
| Study of Combined SGT-53 Plus Gemcitabine/Nab-Paclitaxel for Metastatic Pancreatic Cancer (NCT02340117) | SynerGene Therapeutics, Inc. | 2015-01-01 |
| Simultaneous Integrated Boost Radiotherapy and Concurrent Chemotherapy for Locally Advanced Esophageal Carcinoma (NCT02429622) | Chinese Academy of Medical Sciences | 2015-01-01 |
| Trametinib in Treating Patients With Advanced Melanoma With BRAF Non-V600 Mutations (NCT02296112) | Vanderbilt-Ingram Cancer Center | 2015-01-01 |
| Neoadjuvant Phase II Trial in Patients With T1c Operable, HER2-positive Breast Cancer According to TOP2A Status (NCT02339532) | UNICANCER | 2015-01-01 |