| Phase 2A Clinical Trial Evaluating the Potential Activity and Safety of hMaxi-K Gene for ED (NCT02713789) | Urovant Sciences GmbH | 2015-04-01 |
| Effects of Intranasal Administration of a Single Dose of Oxytocin Using a Novel Device in Adults With Autism Spectrum Disorder (NCT02414503) | OptiNose AS | 2015-04-01 |
| Sympathicomimetic Agonist in Patients With Myeloproliferative Neoplasms With JAK2-mutation (NCT02311569) | Swiss Cancer Institute | 2015-04-01 |
| Intra-arterial Bone-marrow Mononuclear Cells Infusion for Acute Ischemic Stroke (NCT02178657) | Andalusian Initiative for Advanced Therapies | 2015-04-01 |
| Bucillamine for the Treatment of Acute Gout Flare in Subjects With Moderate to Severe Gout (NCT02330796) | Revive Therapeutics, Ltd. | 2015-04-01 |
| S1 Plus Docetaxel Versus Capecitabine Plus Docetaxel First-line Treatment in Patients With Advanced Breast Cancer (NCT02947061) | Chinese Academy of Medical Sciences | 2015-04-01 |
| Local Excision of Clinical T3 Rectal Adenocarcinoma Showing Major Response(ycT0-1) After Neoadjuvant Chemoradiotherapy (NCT02490709) | National Cancer Center, Korea | 2015-04-01 |
| Trial to Evaluate the Efficacy of Simvastatin for Smoking Cessation (NCT02399709) | Poitiers University Hospital | 2015-04-01 |
| A Phase 1/2 Study of High-dose Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure (NCT02346422) | Celladon Corporation | 2015-04-01 |
| Topical Timolol Benefit in Venous Ulcers (NCT02422017) | Centre Hospitalier Universitaire, Amiens | 2015-04-01 |
| Study of Epigallocatechin-3-gallate (EGCG) for Esophagus Protection in Patients With Lung Cancer Receiving Radial Radiotherapy (NCT02577393) | Shandong Cancer Hospital and Institute | 2015-04-01 |
| Micronized dHACM Injectable for the Treatment of Plantar Fasciitis (NCT02427191) | MiMedx Group, Inc. | 2015-03-31 |
| [18F]HX4 PET/CT Imaging for Detection of Hypoxia (NCT02976883) | Nottingham University Hospitals NHS Trust | 2015-03-31 |
| Clinical Application of Dual Sentinel Lymph Node Staining Method in Breast Cancer Patients (NCT02479997) | National Cancer Center, Korea | 2015-03-31 |
| A Phase 1b/2 Study of MEDI4736 With Tremelimumab, MEDI4736 or Tremelimumab Monotherapy in Gastric or GEJ Adenocarcinoma (NCT02340975) | MedImmune LLC | 2015-03-31 |
| Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Toddlers (NCT03205358) | Sanofi Pasteur, a Sanofi Company | 2015-03-31 |
| Pembrolizumab in Treating Patients With Malignant Mesothelioma (NCT02399371) | University of Chicago | 2015-03-31 |
| Study of ORL-1M (D-mannose) in Patients With CDG-Ib (NCT03404869) | Orpha Labs | 2015-03-31 |
| A Phase I/II Study of Ibrutinib in Previously Treated Epidermal Growth Factor Receptor (EGFR) Mutant Non-Small Cell Lung Cancer (NCT02321540) | M.D. Anderson Cancer Center | 2015-03-31 |
| A Study to Determine the Safety and Tolerability of Dupilumab (REGN668/SAR231893) in Patients Aged ≥6 to <18 Years With Atopic Dermatitis (Eczema) (NCT02407756) | Regeneron Pharmaceuticals | 2015-03-31 |
| A Study of Obinutuzumab + Bendamustine (BG) in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL) (NCT02320487) | Genentech, Inc. | 2015-03-31 |
| An Efficacy Study of GSK2269557 Added to Standard Care in Subjects With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease (NCT02294734) | GlaxoSmithKline | 2015-03-31 |
| A Study of Lampalizumab Intravitreal Injections Administered Every Two Weeks or Every Four Weeks to Participants With Geographic Atrophy (NCT02288559) | Genentech, Inc. | 2015-03-30 |
| BTI320 (SUGARDOWN®) on Post-Prandial Hyperglycaemia in Subjects With Pre-Diabetes (NCT02358668) | Chinese University of Hong Kong | 2015-03-30 |
| Nivolumab With or Without Ipilimumab in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Sarcomas (NCT02304458) | National Cancer Institute (NCI) | 2015-03-30 |
| Docetaxel and Capecitabine With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (NCT02524275) | University of Nebraska | 2015-03-30 |
| The Effects of Intravenous Heme Arginate on Heme Oxygenase-1 Expression (HO-1) and Oxidative Stress in the Human Heart (NCT02314780) | Martin Andreas, M.D. | 2015-03-29 |
| Randomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy (NCT02203695) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2015-03-28 |
| Efficacy and Safety of Intranasal MSP-2017 (Etripamil) for the Conversion of PSVT to Sinus Rhythm (NCT02296190) | Milestone Pharmaceuticals Inc. | 2015-03-27 |
| Lower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal Cancer (NCT02368886) | Academic and Community Cancer Research United | 2015-03-27 |
| Efficacy and Safety Study of Guselkumab in the Treatment of Participants With Active Psoriatic Arthritis (PsA) (NCT02319759) | Janssen Research & Development, LLC | 2015-03-27 |
| Phase II Study of Monoclonal Antibody ch14.18/CHO Continuous Infusion in Patients With Primary Refractory or Relapsed Neuroblastoma (NCT02743429) | University Medicine Greifswald | 2015-03-27 |
| Open-Label Study to Evaluate Safety and Efficacy of CCX168 in Subjects With IGA Nephropathy on Stable RAAS Blockade (NCT02384317) | Amgen | 2015-03-27 |
| Study of Colorectal Cancer Patients (Stage IIIC) With Either Regorafenib or Standard of Care (No Treatment) After Adjuvant FOLFOX (NCT02425683) | US Oncology Research | 2015-03-26 |
| Capmatinib, Ceritinib, Regorafenib, or Entrectinib in Treating Patients With BRAF/NRAS Wild-Type Stage III-IV Melanoma (NCT02587650) | University of California, San Francisco | 2015-03-26 |
| Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP) (NCT02386839) | Shire | 2015-03-26 |
| Induction Chemotherapy Before or After Preoperative Chemoradiotherapy and Surgery for Locally Advanced Rectal Cancer (NCT02363374) | Prof. Dr. med. Claus Rödel | 2015-03-25 |
| Immune Checkpoint Inhibition (Tremelimumab and/or MEDI4736) in Combination With Radiation Therapy in Patients With Unresectable Pancreatic Cancer (NCT02311361) | National Cancer Institute (NCI) | 2015-03-25 |
| Immunotherapy With MK-3475 in Surgically Resectable Head and Neck Squamous Cell Carcinoma (NCT02296684) | Washington University School of Medicine | 2015-03-25 |
| Pilot Study, Comparative, Single-center, Randomized, Crossover, Double-blind, Against Placebo, Testing the Effectiveness of Triheptanoin Oil in Alternating Hemiplegia of Childhood (NCT02408354) | Institut National de la Santé Et de la Recherche Médicale, France | 2015-03-25 |
| Allogeneic ADSCs and Platelet-Poor Plasma Fibrin Hydrogel to Treat the Patients With Burn Wounds (ADSCs-BWs) (NCT03113747) | A.A. Partners, LLC | 2015-03-25 |
| Saline Hypertonic in Preschoolers + CT (NCT02950883) | University of Washington, the Collaborative Health Studies Coordinating Center | 2015-03-24 |
| Study of Burosumab (KRN23) in Adults With Tumor-Induced Osteomalacia (TIO) or Epidermal Nevus Syndrome (ENS) (NCT02304367) | Kyowa Kirin, Inc. | 2015-03-24 |
| A Study of Niraparib in Patients With Ovarian Cancer Who Have Received Three or Four Previous Chemotherapy Regimens (NCT02354586) | Tesaro, Inc. | 2015-03-23 |
| Safety and Efficacy of Bictegravir + Emtricitabine/Tenofovir Alafenamide Versus Dolutegravir + Emtricitabine/Tenofovir Alafenamide in HIV-1 Infected, Antiretroviral Treatment-Naive Adults (NCT02397694) | Gilead Sciences | 2015-03-23 |
| Tenecteplase Versus Alteplase Before Endovascular Therapy for Ischemic Stroke (NCT02388061) | Neuroscience Trials Australia | 2015-03-23 |
| Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD (NCT02220985) | Fred Hutchinson Cancer Center | 2015-03-23 |
| Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas (NCT02357810) | Northwestern University | 2015-03-21 |
| Study of MLN9708 as Maintenance Therapy for Patients With Acute Myeloid Leukemia (AML) and High Risk Myelodysplastic Syndrome (MDS) in Remission (NCT02302846) | M.D. Anderson Cancer Center | 2015-03-20 |
| PET/CT Imaging of Angiogenesis in Lung or Head and Neck Cancers Prior or During Chemotherapy With Antiangiogenic Agents (NCT02325349) | Assistance Publique - Hôpitaux de Paris | 2015-03-20 |
| Study of Clinical Efficacy and Safety of Tosedostat in MDS (NCT02452346) | Weill Medical College of Cornell University | 2015-03-20 |
| Safety, Reactogenicity and Immunogenicity Study of Different Formulations of GlaxoSmithKline (GSK) Biologicals' Investigational RSV Vaccine (GSK3003891A), in Healthy Women (NCT02360475) | GlaxoSmithKline | 2015-03-20 |
| Phase 2 Trial to Evaluate Safety and Efficacy of Setmelanotide (RM-493) in Obese Participants With Prader-Willi Syndrome (NCT02311673) | Rhythm Pharmaceuticals, Inc. | 2015-03-19 |
| The ONE Study ATDC Trial (NCT02252055) | Nantes University Hospital | 2015-03-19 |
| A Study to Assess the Efficacy and Safety of Farletuzumab (MORAb 003) in Combination With Carboplatin Plus Paclitaxel or Carboplatin Plus Pegylated Liposomal Doxorubicin (PLD) in Participants With Low CA125 Platinum-sensitive Ovarian Cancer (NCT02289950) | Eisai Inc. | 2015-03-19 |
| A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051) (NCT02332668) | Merck Sharp & Dohme LLC | 2015-03-19 |
| Study Using Xolair in Rush Multi Oral Immunotherapy in Multi Food Allergic Patients (NCT02643862) | Stanford University | 2015-03-18 |
| Effect of Miglustat on the Nasal Potential Difference in Patients With Cystic Fibrosis Homozygous for the F508del Mutation (NCT02325362) | Assistance Publique - Hôpitaux de Paris | 2015-03-17 |
| Efficacy and Safety of Nintedanib Combined With Paclitaxel Chemotherapy for Patients With BRAF wt Metastatic Melanoma (NCT02308553) | Prof. Dr. med. Dirk Schadendorf | 2015-03-17 |
| Fecal Microbiota Transplantation to Treat Recurrent C. Difficile Associated Diarrhea Via Retention Enema or Oral Route (NCT02449174) | The University of Texas Health Science Center, Houston | 2015-03-17 |
| High-Flow Oxygen in Reducing Shortness of Breath Caused by Exercise in Patients With Cancer (NCT02357134) | M.D. Anderson Cancer Center | 2015-03-17 |
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of ABT-494 for the Induction of Symptomatic and Endoscopic Remission in Subjects With Moderately to Severely Active Crohn's Disease Who Have Inadequately Responded to or Are Intolerant to Immunomodulators or Anti-TNF Therapy (NCT02365649) | AbbVie | 2015-03-17 |
| Phase II Trial of Palbociclib in Patients With Metastatic Urothelial Cancer After Failure of First-Line Chemotherapy (NCT02334527) | UNC Lineberger Comprehensive Cancer Center | 2015-03-17 |
| A Study to Evaluate ASP8232 as Add-On Therapy to Angiotensin Converting Enzyme Inhibitor (ACEi) or Angiotensin Receptor Blocker (ARB) in Reducing Albuminuria in Patients With Type 2 Diabetes and Chronic Kidney Disease (NCT02358096) | Astellas Pharma Europe B.V. | 2015-03-17 |
| A Multi-Center, Parallel Design, Randomized, Double-Blind Study to Evaluate the Safety and Efficacy of 6 and 12 mg Proellex® (Telapristone Acetate) Administered Orally in the Treatment of Premenopausal Women With Confirmed Symptomatic Uterine Fibroids (NCT02301897) | Repros Therapeutics Inc. | 2015-03-16 |
| X-82 to Treat Age-related Macular Degeneration (NCT02348359) | Tyrogenex | 2015-03-16 |
| An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille Syndrome (NCT02117713) | Mirum Pharmaceuticals, Inc. | 2015-03-16 |
| Ph2 Nab-paclitaxel With Gemcitabine to Determine Efficacy in Advanced Non-squamous NSCLC. (NCT02405910) | West Virginia University | 2015-03-15 |
| MV-NIS or Investigator's Choice Chemotherapy in Treating Patients With Ovarian, Fallopian, or Peritoneal Cancer (NCT02364713) | Mayo Clinic | 2015-03-13 |
| Study to Assess the Efficacy and Safety of the Epigenetic Modifying Effects of CC-486 (Oral Azacitidine) in Combination With Fulvestrant (NCT02374099) | Celgene | 2015-03-13 |
| Putative Investigational Therapeutics in the Treatment of Patients With Known Ebola Infection (NCT02363322) | National Institute of Allergy and Infectious Diseases (NIAID) | 2015-03-13 |
| Sotrastaurin Acetate in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Leukemia, Prolymphocytic Leukemia, or Richter's Transformation (NCT02285244) | James Blachly | 2015-03-12 |
| A Study to Establish the Safety and Tolerability of Zimura™ (Anti-C5 Aptamer) in Combination With Anti-VEGF Therapy in Subjects With Idiopathic Polypoidal Choroidal Vasculopathy (IPCV) (NCT02397954) | Ophthotech Corporation | 2015-03-12 |
| A Study of Cobimetinib Plus Paclitaxel, Cobimetinib Plus Atezolizumab Plus Paclitaxel, or Cobimetinib Plus Atezolizumab Plus Nab-Paclitaxel as Initial Treatment for Participants With Triple-Negative Breast Cancer That Has Spread (NCT02322814) | Hoffmann-La Roche | 2015-03-12 |
| Tocilizumab (TCZ) in New-onset Type 1 Diabetes (NCT02293837) | National Institute of Allergy and Infectious Diseases (NIAID) | 2015-03-12 |
| Daunorubicin Hydrochloride, Cytarabine, and Nilotinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia (NCT01806571) | Mayo Clinic | 2015-03-12 |
| Effect of Fenugreek Use in Mothers of Preterm on Breast Milk Production and Macronutrient Content (NCT02384655) | Tel-Aviv Sourasky Medical Center | 2015-03-11 |
| 3BNC117 Monoclonal Antibody in HIV-infected Subjects During Treatment Interruption (NCT02446847) | Rockefeller University | 2015-03-11 |
| A Study to Evaluate Safety, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of the Combination of Ibrutinib With Nivolumab in Participants With Hematologic Malignancies (NCT02329847) | Janssen Research & Development, LLC | 2015-03-11 |
| A Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis (NCT02336503) | Botanix Pharmaceuticals | 2015-03-10 |
| Pilot Study of Reparixin for Early Allograft Dysfunction Prevention in Liver Transplantation (NCT03031470) | Dompé Farmaceutici S.p.A | 2015-03-10 |
| Cambridge Brain Mets Trial 1 (NCT02768337) | Cambridge University Hospitals NHS Foundation Trust | 2015-03-10 |
| Consolidation Pembrolizumab Following Chemoradiation in Patients With Inoperable/Unresectable Stage III NSCLC (NCT02343952) | Nasser Hanna, M.D. | 2015-03-09 |
| Effects of Palmitoylethanolamide on Inner Retinal Function in Glaucoma Patients by Pattern Electroretinogram (NCT04088084) | Fondazione IRCCS Policlinico San Matteo di Pavia | 2015-03-09 |
| A Study of Nivolumab in Participants With Metastatic or Unresectable Bladder Cancer (NCT02387996) | Bristol-Myers Squibb | 2015-03-09 |
| A Dose Escalation Study of Gefapixant (AF-219/MK-7264) in Refractory Chronic Cough (MK-7264-010) (NCT02349425) | Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2015-03-09 |
| A Randomized Prospective Clinical Trial of Fel d 1 Peptide Immunotherapy (NCT02311413) | National Institute of Allergy and Infectious Diseases (NIAID) | 2015-03-09 |
| Prevention Trial: Immune-tolerance With Alum-GAD (Diamyd) and Vitamin D3 to Children With Multiple Islet Autoantibodies (NCT02387164) | Lund University | 2015-03-09 |
| LME636 in the Relief of Persistent Ocular Discomfort in Subjects With Severe Dry Eye Disease (NCT02365519) | Alcon, a Novartis Company | 2015-03-09 |
| Cement Augmentation in Preventing Vertebral Body Compression Fracture Following Spine Stereotactic Radiosurgery in Patients With Solid Tumors and Spinal Metastases (NCT02387905) | M.D. Anderson Cancer Center | 2015-03-09 |
| Safety, Tolerability, and Efficacy of TAK-659 in Adults With Relapsed or Refractory Acute Myelogenous Leukemia (AML) (NCT02323113) | Calithera Biosciences, Inc | 2015-03-09 |
| C-Met Inhibitor AMG 337, Oxaliplatin, Leucovorin Calcium, and Fluorouracil in Treating Patients With Advanced Stomach or Esophageal Cancer (NCT02344810) | Eastern Cooperative Oncology Group | 2015-03-06 |
| CGT9486 (Formerly Known as PLX9486) as a Single Agent and in Combination With PLX3397 (Pexidartinib) or Sunitinib in Participants With Advanced Solid Tumors (NCT02401815) | Cogent Biosciences, Inc. | 2015-03-06 |
| Medico-economic Impact of Screening Atopobium Vaginae and Gardnerella Vaginalis in Molecular Biology by "Point-of-care" During Pregnancy (NCT02288832) | Assistance Publique Hopitaux De Marseille | 2015-03-06 |
| Safety, Tolerability, and Efficacy Study of LFX453 in Actinic Keratosis Patients (NCT02404389) | Novartis Pharmaceuticals | 2015-03-05 |
| Rectus Sheath Block: Postoperative Analgesia and Proinflammatory Cytokines (NCT03074097) | Assiut University | 2015-03-05 |
| An Investigational Immuno-therapy Study to Evaluate Safety and Effectiveness in Patients With Melanoma That Has Spread to the Brain, Treated With Nivolumab in Combination With Ipilimumab, Followed by Nivolumab by Itself (NCT02320058) | Bristol-Myers Squibb | 2015-03-05 |
| Preventative Trial of Difluoromethylornithine (DFMO) in High Risk Patients With Neuroblastoma That is in Remission (NCT02395666) | Giselle Sholler | 2015-03-05 |
| Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders (NCT02322047) | Seattle Institute for Biomedical and Clinical Research | 2015-03-03 |
| NBTXR3 Crystalline Nanoparticles and Radiation Therapy in Treating Randomized Patients in Two Arms With Soft Tissue Sarcoma of the Extremity and Trunk Wall (NCT02379845) | Nanobiotix | 2015-03-03 |