| Testing Trametinib as a Potential Targeted Treatment in Cancers With NF1 Genetic Changes (MATCH-Subprotocol S1) (NCT04439318) | National Cancer Institute (NCI) | 2016-02-25 |
| Testing Dasatinib as a Potential Targeted Treatment in Cancers With DDR2 Genetic Changes (MATCH-Subprotocol X) (NCT04439305) | National Cancer Institute (NCI) | 2016-02-25 |
| Trial of Oral Glutamine on Mitochondrial Function in CKD (NCT02838979) | University of Washington | 2016-02-25 |
| Testing GDC-0032 (Taselisib) as a Potential Targeted Treatment in Cancers With PIK3CA Genetic Changes (MATCH-Subprotocol I) (NCT04439175) | National Cancer Institute (NCI) | 2016-02-25 |
| Efficacy and Safety Study of Pembrolizumab (MK-3475) in Participants With Advanced Recurrent Ovarian Cancer (MK-3475-100/KEYNOTE-100) (NCT02674061) | Merck Sharp & Dohme LLC | 2016-02-25 |
| Investigation of Tipifarnib in Treatment of Subjects With Peripheral T-Cell Lymphoma (PTCL) That Have Not Responded to Standard Therapy (NCT02464228) | Kura Oncology, Inc. | 2016-02-25 |
| A Phase 1b/2 Study of Safety and Efficacy of Rociletinib in Combination With MPDL3280A in Patients With Advanced or Metastatic EGFR-mutant NSCLC (NCT02630186) | Clovis Oncology, Inc. | 2016-02-24 |
| MPDL3280A-treatment-IST-UMCG (NCT02478099) | University Medical Center Groningen | 2016-02-24 |
| The PRE-D Trial: Effect of Dapagliflozin, Metformin and Physical Activity in Pre-diabetes (NCT02695810) | Steno Diabetes Center Copenhagen | 2016-02-24 |
| Phase 2/3, Randomized, Double-Masked, Sham-Controlled Trial of QPI-1007 in Subjects With Acute Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) (NCT02341560) | Quark Pharmaceuticals | 2016-02-24 |
| Carrageenan-Containing Gel in Reducing the Rate of HPV Infection in Healthy Participants (NCT02382419) | Rutgers, The State University of New Jersey | 2016-02-24 |
| Study of Sulfatinib in Treating Advanced Medullary Thyroid Carcinoma and Iodine-refractory Differentiated Thyroid Carcinoma (NCT02614495) | Hutchison Medipharma Limited | 2016-02-24 |
| Risk Enabled Therapy After Initiating Neoadjuvant Chemotherapy for Bladder Cancer (RETAIN) (NCT02710734) | Fox Chase Cancer Center | 2016-02-24 |
| A Dose Ranging Study Evaluating Efficacy and Safety of NI-03 (NCT02693093) | Kangen Pharmaceuticals, Inc | 2016-02-24 |
| Eltrombopag in Second Line Adult Primary Immune Thrombosytopenia (NCT02402998) | Gruppo Italiano Malattie EMatologiche dell'Adulto | 2016-02-24 |
| Evaluation of the Efficacy and Safety of HTX-011 for Postoperative Analgesia Following Abdominoplasty Surgery (NCT02689258) | Heron Therapeutics | 2016-02-23 |
| PARP-inhibition and CTLA-4 Blockade in BRCA-deficient Ovarian Cancer (NCT02571725) | New Mexico Cancer Research Alliance | 2016-02-23 |
| Standard of Care Chemotherapy Plus Pembrolizumab for Breast Cancer (NCT02734290) | Providence Health & Services | 2016-02-23 |
| Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma (NCT02584309) | Washington University School of Medicine | 2016-02-22 |
| ACTIMMUNE in Intermediate Osteopetrosis (NCT02666768) | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 2016-02-22 |
| Safety and Tolerability of PBI-4050 and Its Effects on the Biomarkers in Subjects With Alström Syndrome (NCT02739217) | Liminal BioSciences Ltd. | 2016-02-22 |
| An Open Label Investigational Immuno-therapy Trial of Nivolumab in Cancers That Are Advanced or Have Spread (NCT02832167) | Bristol-Myers Squibb | 2016-02-22 |
| Colchicine for Diabetic Nephropathy Trial (NCT02442921) | Sheba Medical Center | 2016-02-22 |
| Study of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC (NCT02463799) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2016-02-22 |
| Study of Poziotinib in Participants With HER2-Positive Metastatic Breast Cancer (NCT02659514) | Spectrum Pharmaceuticals, Inc | 2016-02-22 |
| Evaluation of (R)-Roscovitine Safety and Effects in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation (NCT02649751) | University Hospital, Brest | 2016-02-22 |
| A Study of Durvalumab (MEDI4736) and Monalizumab in Solid Tumors (NCT02671435) | MedImmune LLC | 2016-02-22 |
| Vitamin D to Prevent Severe Asthma Exacerbations (Vit-D-Kids Asthma) (NCT02687815) | Juan Celedon, MD | 2016-02-22 |
| Cognitive Enhancement Through Transcranial Laser Therapy (NCT02851173) | University of Texas at Austin | 2016-02-21 |
| VP-16, Ifosfamide, Dexamethasone, L-asparaginase Chemotherapy in Patients With Extranodal Natural Killer T Cell Lymphoma (VIDL+ASCT) (NCT02544425) | Samsung Medical Center | 2016-02-21 |
| Immediate or Delayed Naturopathic Medicine in Combination With Neo-Adjuvant Chemotherapy for Breast Cancer (NCT02486796) | Midwestern Regional Medical Center | 2016-02-19 |
| Dasatinib and Venetoclax in Treating Patients With Philadelphia Chromosome Positive or BCR-ABL1 Positive Early Chronic Phase Chronic Myelogenous Leukemia (NCT02689440) | M.D. Anderson Cancer Center | 2016-02-19 |
| Administration of Mesenchymal Stem Cells in Patients With Chronic Ischemic Cardiomyopathy (MESAMI2) (NCT02462330) | University Hospital, Toulouse | 2016-02-19 |
| TIvantinib as Maintenance Treatment in Extended Small-cell Lung Cancer (TIMES) (NCT02608411) | Istituto Oncologico Veneto IRCCS | 2016-02-19 |
| Study to Assess Various Sunitinib Schedules in Renal Cell Carcinoma (NCT02689167) | Centre Hospitalier Universitaire de Besancon | 2016-02-19 |
| Influence of Carboxypeptidase D (CPD) Gene on Body Weight and Fat Mass Reduction by Perindopril in Obese Subjects (NCT02777489) | Gene PreDiT | 2016-02-18 |
| Safety and Efficacy Study of Subcutaneous Belimumab and Intravenous Rituximab Co-administration in Subjects With Primary Sjogren's Syndrome (NCT02631538) | GlaxoSmithKline | 2016-02-17 |
| Fulvestrant (F)+Placebo vs F+Palbociclib First Line for Postmenopausal Hormone Receptor+ Advanced Breast Cancer (NCT02690480) | Spanish Breast Cancer Research Group | 2016-02-17 |
| Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Three-times Weekly Dosing of GSK1278863 in Hemodialysis-dependent Subjects With Anemia Associated With Chronic Kidney Disease Who Are Switched From a Stable Dose of an Erythropoiesis-stimulating Agent (NCT02689206) | GlaxoSmithKline | 2016-02-17 |
| 12 Weeks of Ledipasvir (LDV)/Sofosbuvir (SOF) With Weight-based Ribavirin vs. 24 Weeks of LDV/SOF (NCT02605304) | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | 2016-02-17 |
| A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee (NCT02611466) | Astellas Pharma Europe B.V. | 2016-02-16 |
| Study of Subretinal Implantation of Human Embryonic Stem Cell-Derived RPE Cells in Advanced Dry AMD (NCT02590692) | Regenerative Patch Technologies, LLC | 2016-02-16 |
| Interest of the 18F-DOPA-PET Imaging in Metastatic Melanoma Treated With B-RAF Inhibitors: a Pilot Study (NCT02038348) | Assistance Publique Hopitaux De Marseille | 2016-02-16 |
| Glembatumumab Vedotin in Treating Patients With Recurrent or Refractory Osteosarcoma (NCT02487979) | National Cancer Institute (NCI) | 2016-02-16 |
| A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D (NCT03546621) | Hepatera Ltd. | 2016-02-16 |
| Efficacy and Safety Study of BMS-986142 in Patients With Moderate to Severe Rheumatoid Arthritis (NCT02638948) | Bristol-Myers Squibb | 2016-02-16 |
| A Phase 2 Study to Evaluate the Efficacy and Safety of JointStem in Treatment of Osteoarthritis (NCT02674399) | Nature Cell Co. Ltd. | 2016-02-16 |
| A Study of the Effect of XmAb®5871 in Patients With Systemic Lupus Erythematosus (NCT02725515) | Xencor, Inc. | 2016-02-16 |
| Rivaroxaban Versus Low-molecular-weight Heparin for Preventing Thrombosis in Cancer Patients (NCT03282643) | Capital Medical University | 2016-02-16 |
| FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer (NCT02508077) | City of Hope Medical Center | 2016-02-16 |
| A Safety and Efficacy Study of Estradiol Vaginal Capsule in Postmenopausal Women With Vulvovaginal Atrophy (NCT02670785) | Warner Chilcott | 2016-02-15 |
| Nivolumab in Combination With Ipilimumab (Part 1); Nivolumab Plus Ipilimumab in Combination With Chemotherapy (Part 2) as First Line Therapy in Stage IV Non-Small Cell Lung Cancer (NCT02659059) | Bristol-Myers Squibb | 2016-02-15 |
| Safety and Immunogenicity Study of Trivalent P2-VP8 Subunit Rotavirus Vaccine in Adults, Toddlers and Infants (NCT02646891) | PATH | 2016-02-15 |
| Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult ETP-ALL (NCT03553238) | Nanfang Hospital, Southern Medical University | 2016-02-14 |
| Precision Diagnosis Directing HDACi Chidamide Target Therapy for Adult T-LBL/ALL (NCT03564704) | Nanfang Hospital, Southern Medical University | 2016-02-14 |
| Precision Diagnosis Directing HDACi and TKI Target Therapy for Adult Ph-like ALL (NCT03564470) | Nanfang Hospital, Southern Medical University | 2016-02-14 |
| Screening Trial of Nivolumab With Image Guided, Stereotactic Body Radiotherapy (SBRT) Versus Nivolumab Alone in Patients With Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC) (NCT02684253) | Memorial Sloan Kettering Cancer Center | 2016-02-11 |
| Safety and Efficacy of Entospletinib (ENTO [GS-9973]) Combined With Vincristine (VCR) in Adult Participants With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma (NHL) (NCT02568683) | Gilead Sciences | 2016-02-11 |
| Open-label Extension Study to Evaluate the Safety of Long-term Twice-monthly Administration of Somavaratan in Adult Growth Hormone Deficiency (AGHD) (NCT02719990) | Versartis Inc. | 2016-02-11 |
| An Investigational Immuno-therapy Safety and Effectiveness Study of Nivolumab in Combination With Brentuximab Vedotin to Treat Non-Hodgkin Lymphomas (NCT02581631) | Bristol-Myers Squibb | 2016-02-11 |
| A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's Sarcoma (NCT02511132) | Gradalis, Inc. | 2016-02-10 |
| EXCELLENT (EXpanded CELL ENdocardiac Transplantation) (NCT02669810) | CellProthera | 2016-02-10 |
| Tagraxofusp (SL-401) in Participants With Chronic Myelomonocytic Leukemia (CMML) and Myelofibrosis (MF) (NCT02268253) | Stemline Therapeutics, Inc. | 2016-02-10 |
| Tideglusib vs. Placebo in the Treatment of Adolescents With Autism Spectrum Disorders (NCT02586935) | Holland Bloorview Kids Rehabilitation Hospital | 2016-02-10 |
| Study of AZD6094 (Volitinib) in Advanced Gastric Adenocarcinoma Patients With MET Amplification as a Third-line Treatment (NCT02449551) | Samsung Medical Center | 2016-02-10 |
| Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis (NCT03204058) | Government Dental College and Research Institute, Bangalore | 2016-02-10 |
| Study of Pembrolizumab (MK-3475) and Pembrolizumab With Other Investigational Agents in Participants With High Risk Non-muscle Invasive Bladder Cancer (MK-3475-057/KEYNOTE-057) (NCT02625961) | Merck Sharp & Dohme LLC | 2016-02-10 |
| Conservative Iron Chelation as a Disease-modifying Strategy in Parkinson's Disease (NCT02655315) | University Hospital, Lille | 2016-02-09 |
| Use of Lexiscan for Myocardial Stress Perfusion Computed Tomography With a 3rd Generation Dual Source CT System (NCT03103061) | Medical University of South Carolina | 2016-02-09 |
| A Study of Elotuzumab in Combination With Pomalidomide and Low Dose Dexamethasone and Elotuzumab in Combination With Nivolumab in Patients With Multiple Myeloma Relapsed or Refractory to Prior Treatment With Lenalidomide. (NCT02612779) | Bristol-Myers Squibb | 2016-02-09 |
| Preoperative Use of Tocotrienol From Annatto Bixa Orellana L. in Breast Cancer Patients: a Prospective Clinical Trial. (NCT04496492) | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 2016-02-09 |
| Testosterone in Metastatic Renal Cell Carcinoma Patients (NCT03379012) | Kidney Cancer Research Bureau | 2016-02-08 |
| A Study of Pembrolizumab With Standard Treatment in Patients With Recurrent Platinum-resistant Ovarian Cancer (NCT02608684) | Cedars-Sinai Medical Center | 2016-02-08 |
| Ibrutinib in Treating Minimal Residual Disease in Patients With Chronic Lymphocytic Leukemia After Front-Line Therapy (NCT02649387) | Mayo Clinic | 2016-02-08 |
| Neoadjuvant Triplet Chemotherapy Regimen in Patients With Locally Advanced Rectal Cancer (NCT03443661) | Aiping Zhou | 2016-02-06 |
| A Pilot Study of Ruxolitinib in Secondary Hemophagocytic Syndrome (NCT02400463) | University of Michigan Rogel Cancer Center | 2016-02-05 |
| Trial to Evaluate the Safety of Talimogene Laherparepvec Injected Into Tumors Alone and in Combination With Systemic Pembrolizumab MK-3475-611/Keynote-611 (NCT02509507) | Amgen | 2016-02-05 |
| Anakinra and Kawasaki Disease (NCT02390596) | Assistance Publique - Hôpitaux de Paris | 2016-02-05 |
| Assessment of Radiolabeled rhAnnexin V-128 in Infective Endocarditis (NCT02459613) | Institut National de la Santé Et de la Recherche Médicale, France | 2016-02-05 |
| Trial Evaluating Maintenance Olaparib in Patients With Platinum-sensitive Advanced Non-small Cell Lung Cancer (NCT02679963) | Gustave Roussy, Cancer Campus, Grand Paris | 2016-02-05 |
| Study of the Effect of Serelaxin on High-sensitivity Cardiac Troponin I (Hs-cTnI) Release in Patients With Chronic Heart Failure (NCT02625922) | Novartis Pharmaceuticals | 2016-02-05 |
| Trial to Evaluate the Safety of TTAC-0001(Tanibirumab) in Recurrent Glioblastoma (NCT03033524) | PharmAbcine | 2016-02-04 |
| The Rapid Study: Randomized Phase II Study To Expedite Allogeneic Transplant With Immediate Haploidentical Plus Unrelated Cord Donor Search Versus Matched Unrelated Donor Search For AML And High-Risk MDS Patients (NCT02648932) | University of Chicago | 2016-02-04 |
| Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma (NCT02484443) | National Cancer Institute (NCI) | 2016-02-04 |
| Nab-Paclitaxel and Atezolizumab Before Surgery in Treating Patients With Triple Negative Breast Cancer (NCT02530489) | M.D. Anderson Cancer Center | 2016-02-04 |
| Sequential Regimen of Bendamustin-Debulking Followed by Ofatumumab and Ibrutinib in CLL Patients (CLL2-BIO) (NCT02689141) | German CLL Study Group | 2016-02-04 |
| Study of Intratumoral G100 With Or Without Pembrolizumab or Rituximab In Participants With Follicular Non-Hodgkin's Lymphoma (MK-3475-174/IMDZ-G142) (NCT02501473) | Immune Design, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2016-02-03 |
| XC8 in the Treatment of Patients With Acute Respiratory Viral Infection (NCT03441373) | PHARMENTERPRISES LLC | 2016-02-03 |
| A Study to Investigate the Effect of a Nitric Oxide Supplementation on Pre- and Mildly Hypertensive Adults (NCT02679248) | KGK Science Inc. | 2016-02-03 |
| Use of Regorafenib in Recurrent Epithelial Ovarian Cancer (NCT02736305) | National Cancer Centre, Singapore | 2016-02-03 |
| Sitagliptin for Prevention of Acute Graft Versus-Host Disease After Allogeneic Hematopoietic Stem Cell Transplantation (NCT02683525) | Sherif S. Farag | 2016-02-03 |
| Prulifloxacin in Chronic Bacterial Prostatitis (CBP) (NCT03201796) | Aziende Chimiche Riunite Angelini Francesco S.p.A | 2016-02-02 |
| Neoadjuvant and Adjuvant Checkpoint Blockade (NCT02519322) | M.D. Anderson Cancer Center | 2016-02-02 |
| Trial Comparing Early Laparoscopic Enterolysis Versus Nonoperative Management for High-grade SBO (NCT02692638) | Yale University | 2016-02-02 |
| Treatment of Chronic Constipation in Parkinson's Disease (NCT04569656) | IRCCS San Raffaele Roma | 2016-02-02 |
| Sublingual Fentanyl for the Management of Breakthrough Pain (NCT02514252) | M.D. Anderson Cancer Center | 2016-02-02 |
| Endothelial Dysfunction in Resuscitated Cardiac Arrest (NCT02685618) | Pär Johansson | 2016-02-01 |
| Study of Mogamulizumab + Nivolumab in Subjects w/Locally Advanced or Metastatic Solid Tumors (NCT02705105) | Kyowa Kirin, Inc. | 2016-02-01 |
| Administration of Rifaximin to Improve Liver Regeneration and Outcome Following Major Liver Resection (NCT02555293) | RWTH Aachen University | 2016-02-01 |
| Phase 2 Study of Sym004 for Adult Patients With Recurrent Glioblastoma (NCT02540161) | Annick Desjardins | 2016-02-01 |