| Exploration of Sintilimab + Bevacizumab + AG Chemotherapy as First-Line Treatment for Unresectable Advanced/Metastatic Cholangiocarcinoma (NCT07328802) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-01-01 |
| dApagliflozin SC0062 and Prevention of Renal Injury; a Randomized Evaluation (NCT06072326) | University Medical Center Groningen | 2026-01-01 |
| Cabozantinib Dose Skipping as an Alternative to Dose Reductions (NCT07077161) | dr. Tom van der Hulle | 2026-01-01 |
| Using TropoCells(R) Autologous Platelet-Rich Fibrin (PRF) to Treat Chronic Non-Healing Wounds (NCT07318792) | Estar Medical dba Medical Technologies, LTD | 2026-01-01 |
| Phase II Clinical Trial: Multi-dosing the BCG Vaccine for Fibromyalgia (NCT03582085) | Massachusetts General Hospital | 2026-01-01 |
| Ademetionine in Obstructive Hypertrophic Cardiomyopathy (NCT07367724) | China National Center for Cardiovascular Diseases | 2026-01-01 |
| Etrasimod for Immune Checkpoint Inhibitor Diarrhea and Colitis (NCT06521762) | Yale University | 2026-01-01 |
| HB-adMSCs vs Placebo for the Treatment of Juvenile Idiopathic Arthritis (NCT06623240) | Hope Biosciences Research Foundation | 2026-01-01 |
| Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia (NCT07279740) | Sunnybrook Health Sciences Centre | 2026-01-01 |
| EZH2 Inhibitor Zeprumetostat in Combination Therapy for Patients With Relapsed or Refractory Mature T-cell and NK-cell Lymphomas (NCT07339527) | Sun Yat-sen University | 2026-01-01 |
| Phase 2 Randomized Study of PG-102 vs Placebo and Semaglutide in Type 2 Diabetes Mellitus (NCT07187856) | ProGen. Co., Ltd. | 2026-01-01 |
| CApecitabine Prior to TUmor Resection in Ent Oncology (CAPTURE) (NCT07254962) | Sir Mortimer B. Davis - Jewish General Hospital | 2026-01-01 |
| Combination Therapy With Infliximab and Tofacitinib for Acute Severe Ulcerative Colitis - CINTO Trial (NCT07297069) | Asian Institute of Gastroenterology, India | 2026-01-01 |
| Evaluation of UCPVax Vaccine +/- Pembrolizumab Combined With Standard Treatment as Adjuvant Therapy in Patients With Unmethylated MGMT Glioblastoma (NCT07347210) | Centre Hospitalier Universitaire de Besancon | 2026-01-01 |
| 4-Aminopyridine to Treat Skin Burns (NCT06596434) | John Elfar | 2026-01-01 |
| Investigation of Vancomycin Efficacy in Patients With Ulcerative Colitis and Primary Sclerosing Cholangitis (NCT07341282) | McMaster University | 2026-01-01 |
| Rare Tumor Focused Platform Study of Innovative Therapies and Technologies (PLATFORM2) (NCT07307053) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2026-01-01 |
| Metastatic Non-Familial Adenocarcinoma Maintenance Therapy With DZ-002: Heptamine Carboxymethine Dye Conjugate (NCT07344220) | Hoag Memorial Hospital Presbyterian | 2026-01-01 |
| 125I Seed Implantation Plus Systemic Therapy for Oligoprogressive NSCLC or Colorectal Cancer (NCT07333651) | Li Min | 2026-01-01 |
| Clinical Study on the Early Bactericidal Activity of Contezolid Against Mycobacterium Abscessus Disease (NCT07372781) | Beijing Chest Hospital | 2026-01-01 |
| This is a Phase I/II Interventional, Open-label Treatment Study Designed to Evaluate the Safety and Efficacy of Anti CD 19/22 CAR- T Cells Immunotherapy for Adults With Relapsed or Refractory Acute Lymphoblastic Leukemia/Lymphoma. (NCT07162571) | Minsk Scientific-Practical Center for Surgery, Transplantation and Hematology | 2026-01-01 |
| Firmonertinib 160 mg in Patients With EGFR-Mutant Advanced NSCLC Demonstrating SD After 8 Week Induction With Firmonertinib 80 mg (NCT07298148) | Peking University Cancer Hospital & Institute | 2026-01-01 |
| Evaluating The Role Of Montelukast In Management Of Acute Bronchiolitis (NCT07770464) | Pakistan Institute of Medical Sciences | 2026-01-01 |
| IUD and Norethindrone Acetate for Treatment of Endometriosis (NCT04948489) | Boston Children's Hospital | 2026-01-01 |
| Zanidatamab Combined With Chemotherapy as Neoadjuvant Therapy for HER2-high Expression G/GEJC (NCT07273981) | Xijing Hospital | 2026-01-01 |
| CD19/CD22 CAR-T as First-line Consolidation in Follicular Lymphoma (NCT07587840) | Liping Dou | 2026-01-01 |
| Efficacy, Safety and Tolerability of Low Sodium Oxybate for Nocturnal Cluster Headache Attacks (NCT06950281) | Leiden University Medical Center | 2026-01-01 |
| Evaluation of the Effectiveness of a Cardiac Coherence Exercise on MRI Success and Image Quality in Claustrophobic Patients (NCT07309328) | Fondation Ophtalmologique Adolphe de Rothschild | 2026-01-01 |
| A Phase II Clinical Trial of Ivonescimab Plus Third-generation EGFR-TKIs in Advanced Non-small Cell Lung Cancer With Gradual or Potential Progression After EGFR-TKIs Treatment (NCT07669051) | Shandong Cancer Hospital and Institute | 2026-01-01 |
| Epileptic Hippocampus in Alzheimer's Disease (NCT05899764) | University of California, Los Angeles | 2026-01-01 |
| Clinical Trial Investigating the Effect of Exosomes as a Complementary Treatment in Severe to Moderate Erectile Dysfunction (NCT07319533) | Labbafinejad Medical Center | 2026-01-01 |
| Olaptesed With Pembrolizumab and Nanoliposomal Irinotecan or Gemcitabine/Nab-Paclitaxel in MSS Pancreatic Cancer (NCT04901741) | TME Pharma AG | 2026-01-01 |
| QL1706-SOX vs SOX Alone as Neoadjuvant Therapy for Resectable Diffuse-Type Gastric Cancer (NCT07315035) | The First Affiliated Hospital with Nanjing Medical University | 2026-01-01 |
| A Hypoxia-Inducible CAR-T Cell Targeting AXL and CD73 for Advanced Gastric Cancer (NCT07333573) | Shanghai Zhongshan Hospital | 2026-01-01 |
| A Multicenter Clinical Trial Evaluating the Efficacy and Safety of Taurine as an Adjunctive Therapy in Multiple Sclerosis (NCT07263607) | Sichuan Academy of Medical Sciences | 2026-01-01 |
| The Impact of Force Feedback in the dV5 Robotic Surgical System on Learning Curve and Safety in Robot-Assisted Radical Prostatectomy - A Prospective, Single-Center, Investigator-Initiated Clinical Trial (NCT07247175) | Seong Soo Jeon | 2026-01-01 |
| The Effect of Daily Supplementation With Humiome® Post LB on Gastrointestinal Symptoms in Female Athletes (NCT07366931) | Liverpool John Moores University | 2026-01-01 |
| Image-Guided 125I Seed Implantation Plus Standard Systemic Therapy for Patients With Multiple Metastatic Lesions (NCT07333664) | Li Min | 2026-01-01 |
| Safety and Efficacy of Leucine-Restricted Diet Combined With Chemotherapy and Immunotherapy in Advanced Gastric Cancer (NCT07537348) | Qilu Hospital of Shandong University | 2026-01-01 |
| Sevoflurane Sedation in Patients With Septic Shock (NCT03643367) | University of Zurich | 2026-01-01 |
| Lingual Nerve Disruption to Augment Neoadjuvant Chemoimmunotherapy in Locally Advanced Tongue Cancer (NCT07346807) | Shanghai Zhongshan Hospital | 2026-01-01 |
| Golidocitinib Combined With Selinexor for CAEBVD (NCT07369739) | Beijing Friendship Hospital | 2026-01-01 |
| Exploratory Study of CD22/CD19 Dual-Target CAR-T Cell Therapy as Consolidation Treatment After First Remission in High-Risk B-Cell Acute Lymphoblastic Leukemia (NCT07575971) | Liping Dou | 2026-01-01 |
| Genetic Subtype-matched Targeted Therapy for the Treatment of Newly Diagnosed DLBCL With TP53 Mutation (NCT07499271) | The First Affiliated Hospital of Soochow University | 2026-01-01 |
| Darolutamide+ADT Post-RP w/o ePLND in hrPC: Briganti 2019 (NCT07282197) | Peking University First Hospital | 2026-01-01 |
| Plan A Occlusion and Reversal System Feasibility Study (NCT07361120) | Next Life Sciences | 2026-01-01 |
| Dynamic Circulating Tumor DNA Monitoring to Guide Systemic Therapy in Gastric Cancer (NCT07517107) | Fudan University | 2026-01-01 |
| Immunotherapy Before Transplantation for Skin Cancer Prevention in Organ Transplant Recipients (NCT04329221) | Massachusetts General Hospital | 2026-01-01 |
| A Prospective, Single-Arm, Phase II Clinical Study of Neoadjuvant Therapy With Pucotenlimab, Lenvatinib, and Temozolomide for Resectable Head and Neck Mucosal Melanoma (PLT-NAT-HNMM-II) (NCT07353073) | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 2026-01-01 |
| Sacituzumab Govitecan and Intrathecal Chemotherapy for Treating Leptomeningeal Metastases From Her2-negative Breast Cancer (NCT06462092) | Guangzhou Medical University | 2026-01-01 |
| Hippocampus-Protective Radiotherapy Combined With Osimertinib for Symptomatic Brain Metastases in EGFR-Mutated Lung Cancer (NCT07505173) | Tianjin Medical University Cancer Institute and Hospital | 2026-01-01 |
| Virtual tES Device Treatment for Parkinson's Disease Motor Symptoms (NCT07182058) | U: The Mind Company | 2026-01-01 |
| The Efficacy and Safety of ARNI on the Outcome of Advanced Lung Cancer With Concurrent Hypertension (NCT07261098) | Shanghai Chest Hospital | 2026-01-01 |
| Dynamic 82-Rb Positron Emission Tomography (PET) for the Grading of KIDney Carcinoma (NCT07346404) | Assistance Publique - Hôpitaux de Paris | 2026-01-01 |
| Rutin and Vitamin C in Patients With Metabolic Dysfunction-associated Steatotic Liver Disease (MASLD) (NCT07310407) | Ain Shams University | 2026-01-01 |
| Neoadjuvant Camrelizumab With Palbociclib for Resectable Esophageal Squamous Cell Carcinoma (NCT07191977) | West China Hospital | 2026-01-01 |
| Effect of Liposome Bupivacaine Serratus Plane Block on Postoperative Hyperalgesia and Chronic Post-surgical Pain in Patients Undergoing Radical Mastectomy (NCT07289178) | First Affiliated Hospital of Kunming Medical University | 2026-01-01 |
| Radioimmunotherapy Conditioning With 131I- Apamistamab for Allogeneic Transplant in Relapse/Refractory AML (NCT07157514) | Actinium Pharmaceuticals | 2026-01-01 |
| Diclofenac for Prevention of Post-ERC Pancreatitis (NCT03595150) | Karolinska Institutet | 2026-01-01 |
| A Study to Evaluate the Effects of the Combination of GI-102 With GIB-7 on Biomarkers of Aging in Healthy Adults and Cancer Survivors (NCT07363057) | GI Innovation, Inc. | 2026-01-01 |
| Phase Ib/II Study to Evaluate the Safety and Efficacy of IBI363 in Combination With Chemotherapy as Second-Line Therapy for Unresectable Locally Advanced or Metastatic Pancreatic Cancer (NCT07342725) | Ruijin Hospital | 2026-01-01 |
| Efficacy of Probenecid on Cluster Seizures During Anti Seizure Medication Withdrawal in Presurgical Focal Epilepsy Video-EEG Monitoring (NCT07318870) | Fondation Ophtalmologique Adolphe de Rothschild | 2026-01-01 |
| A Study to Investigate the Biomarkers of Hemay005 in Adult Participants With Moderate to Severe COPD (NCT07314242) | Ganzhou Hemay Pharmaceutical Co., Ltd | 2026-01-01 |
| Glymphatic Function TMS Study (NCT07192913) | University of Arizona | 2026-01-01 |
| A Multicenter, Randomized Controlled Phase II Study of Short-Course Radiotherapy Followed by Sequential PD-1 Inhibitor and FOLFOX Chemotherapy Versus Long-Course Chemoradiotherapy for High-Risk Locally Advanced pMMR/MSS Lower Rectal Adenocarcinoma (STAR Trial) (NCT07669220) | Sixth Affiliated Hospital, Sun Yat-sen University | 2026-01-01 |
| Efficacy and Safety of Allogenic Cultured Adipose-derived Mesenchymal Stromal Cell Injections on MoUth Fibrosis and Handicap in Patients With Systemic sclEroderma (NCT07326033) | University Hospital, Toulouse | 2026-01-01 |
| BCMA-CD19 cCAR T for the Treatment of Refractory Lupus (NCT07328581) | iCell Gene Therapeutics | 2026-01-01 |
| G-CSF Combined With IL-11 on Hematopoietic Reconstitution After Autologous Hematopoietic Stem Cell Transplantation (NCT07362810) | Fudan University | 2026-01-01 |
| Furmonertinib 160mg vs 80mg + Chemotherapy in EGFR-Mutated NSCLC With Brain Metastases: Efficacy and Safety Study (NCT07365410) | Tianjin Medical University Cancer Institute and Hospital | 2026-01-01 |
| Liposomal Irinotecan Combined With Sintilimab and Anlotinib in the Treatment of Recurrent or Persistent Ovarian Clear Cell Carcinoma (NCT07239622) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2026-01-01 |
| Indocyanine Green-guided Omental Shield Anastomosis for Cervical Esophagogastric Anastomosis in Minimally Invasive McKeown Esophagectomy (NCT07376876) | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 2026-01-01 |
| A 2-Part Study to Assess Efficacy, Safety and Tolerability of BMB-101 for the Treatment of Patients With Prader-Willi Syndrome. (NCT07266324) | Bright Minds Biosciences Pty Ltd | 2026-01-01 |
| Efficacy and Safety of Sequential Autologous Hematopoietic Stem Cell Transplantation Combined With Tafasitamab, Lenalidomide, and Standard Immunochemotherapy for Relapsed/Refractory Diffuse Large B-cell Lymphoma (NCT07621406) | The First Affiliated Hospital of Soochow University | 2026-01-01 |
| Brain State-dependent PCMS in Chronic Stroke (NCT04830163) | University of Texas at Austin | 2026-01-01 |
| Evaluating Benzoyl Peroxide for Preventing Recurrence of HSV-1 Outbreaks With Rescue Crossover Option (NCT07032649) | Greg Bew | 2026-01-01 |
| Study to Assess Safety, Efficacy and Persistence of ACE1831, in Subjects With IgG4-Related Disease (NCT07061938) | Acepodia Biotech, Inc. | 2026-01-01 |
| A Pilot Study Evaluating β-hydroxybutyrate Supplementation Concomitant to Short-Course Radiotherapy Followed by Immunotherapy Combined With CAPEOX Neoadjuvant Therapy in Patients With Locally Advanced Rectal Cancer (NCT07239466) | Tao Zhang | 2026-01-01 |
| Tolerance, Safety, Efficacy, and Pharmacokinetics of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) Using Paclitaxel for Platinum-resistant Recurrent Ovarian Cancer (NCT07273396) | Seoul National University Hospital | 2026-01-01 |
| MRG003 Induction and Capecitabine Maintenance With PD-1 in Locally Recurrent NPC (NCT07331428) | Fujian Cancer Hospital | 2026-01-01 |
| Clinical Study of Adjuvant Surufatinib Therapy for Postoperative High-risk Neuroendocrine Tumors Based on the Ninth Edition of the AJCC Staging System (NCT07279532) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-01-01 |
| A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor Tissue (NCT07248020) | Chang Gung Memorial Hospital | 2026-01-01 |
| Safety and Efficacy of Leucine-Restricted Diet Combined With Neoadjuvant Chemotherapy and Immunotherapy in Gastric Cancer (NCT07537361) | Qilu Hospital of Shandong University | 2026-01-01 |
| Study of TYK-01054 Capsules in Patients With Advanced Solid Tumors (NCT07282873) | TYK Medicines, Inc | 2026-01-01 |
| Disitamab Vedotin Combined With Platinum and Bevacizumab as First-Line and Maintenance Therapy for HER2-Expressing, HRD-Negative High-Risk Ovarian Cancer: A Multicenter, Non-Randomized, Single-Arm Phase II Clinical Study (NCT07311577) | Jiangsu Cancer Institute & Hospital | 2026-01-01 |
| Unrelated Cord Blood Transplantation for EBV-associated Lymphoproliferative Disorders (NCT07381738) | Fudan University | 2026-01-01 |
| A Study Testing Emactinib Sulfate With Chemotherapy and Immunotherapy Before Surgery for Advanced Head and Neck Cancer (NCT07457346) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-01-01 |
| Safety and Efficacy of Lidocaine Versus Ketamine Infusion for Resistant Orofacial Pain (NCT07250867) | Assiut University | 2026-01-01 |
| Clinical and Radiographic Success Rate of Pulpotomy Versus Pulpectomy for Management of Primary Teeth With Deep Caries (NCT06293521) | Cairo University | 2026-01-01 |
| Sac-TMT Combined With Bevacizumab in TNBC With Brain Metastases (NCT07623577) | Fudan University | 2026-01-01 |
| Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer (NCT07216404) | Alan Davis | 2026-01-01 |
| EB-OC for the Treatment of Focal Chondral/Osteochondral Defects in the Knee (NCT06895889) | Epibone, Inc. | 2026-01-01 |
| A Clinical Study on the Efficacy and Safety of All-trans Retinoic Acid Combined With VAC Regimen in the Treatment of Intermediate-to-high-risk Rhabdomyosarcoma (NCT07355855) | Fudan University | 2026-01-01 |
| 125I Seed Brachytherapy Combined With Immunotherapy for Primary, Recurrent, or Metastatic Malignant Tumors (NCT07277777) | Li Min | 2026-01-01 |
| Neoadjuvant Sacituzumab Tirumotecan and Limertinib for Potentially Resectable Stage Ⅲ EGFR-mutant Non-small Cell Lung Cancer (NCT07323056) | Shanghai Pulmonary Hospital, Shanghai, China | 2026-01-01 |
| Mesenchymal Stem Cells for Chronic Kidney Diseases (NCT07240987) | The First Affiliated Hospital of Air Force Medicial University | 2026-01-01 |
| Aerosolized Mesenchymal Stem Cell-Derived Exosomes for the Prevention and Treatment of Radiation-Induced Oral Mucositis (NCT07312656) | First Affiliated Hospital of Guangxi Medical University | 2026-01-01 |
| Radiotherapy Plus CAPOX, and Iparomlimab and Tuvonralimab (QL1706) as Neoadjuvant Therapy for LARC (NCT07291401) | Zhongnan Hospital | 2026-01-01 |
| Hyperprogression in PD-L1 ≥ 50% NSCLC: a Biomarker Guided Phase 2 Trial (NCT07274384) | Università Vita-Salute San Raffaele | 2026-01-01 |
| Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial (NCT07293078) | MetroWest Artificial Intelligence Research Workgroup | 2026-01-01 |
| A Study Evaluating Neoadjuvant Chemotherapy, Concurrent Chemoradiotherapy Combined With Dual Immune Checkpoint Blockade in Patients With Locally Advanced Non-Small Cell Lung Cancer (NCT07103395) | Sun Yat-sen University | 2026-01-01 |