| A Study of RO7123520 to Evaluate the Safety and Efficacy in Participants With Moderately To Severely Active Rheumatoid Arthritis (RA) Who Are Inadequately Responding to Anti-Tumor Necrosis Factor (TNF)-Alpha Therapy (NCT03001219) | Hoffmann-La Roche | 2016-12-22 |
| Study of Efficacy and Safety of CJM112 in Patients With Moderate to Severe Inflammatory Acne (NCT02998671) | Novartis Pharmaceuticals | 2016-12-22 |
| A Confirmatory Safety and Efficacy Study of BBI-4000 in Subjects With Axillary Hyperhidrosis (NCT03024255) | Botanix Pharmaceuticals | 2016-12-22 |
| Pembrolizumab, Paclitaxel, and Carboplatin in Patients With Advanced Stage Epithelial Ovarian Cancer (EOC). (NCT02834975) | University of Miami | 2016-12-22 |
| A Study to Evaluate the Safety and Efficacy of THR-317 for the Treatment of Diabetic Macular Oedema (DME) (NCT03071068) | ThromboGenics | 2016-12-22 |
| A Study for Subjects With Prostate Cancer Who Previously Participated in an Enzalutamide Clinical Study (NCT02960022) | Astellas Pharma Global Development, Inc. | 2016-12-22 |
| ODM-207 in Patients With Advance Solid Tumours (NCT03035591) | Orion Corporation, Orion Pharma | 2016-12-22 |
| A Study to Investigate the Safety, Pharmacokinetics, and Efficacy of Combination Treatment of AL-335, Odalasvir, and Simeprevir in Japanese Participants With Chronic Hepatitis C Genotype 1 or 2 Virus Infection, With or Without Compensated Cirrhosis Who Are Direct Acting Antiviral Treatment-naive (NCT02993250) | Janssen Pharmaceutical K.K. | 2016-12-21 |
| Ruxolitinib vs Allogeneic SCT for Patients With Myelofibrosis According to Donor Availability (NCT03333187) | Universitätsklinikum Hamburg-Eppendorf | 2016-12-21 |
| Different Concentrations of Potassium Nitrate in In-office Tooth Bleaching Sensitivity (NCT03323372) | Universidade Federal do Amazonas | 2016-12-21 |
| Study of the Efficacy, Safety and Pharmacokinetics of Pamiparib (BGB-290) in Participants With Advanced Solid Tumors (NCT03333915) | BeiGene | 2016-12-21 |
| Trial of Rad-223 Activity in Asymptomatic Patients With mCRPC While on Abiraterone or Enzalutamide Besides AR-V7 Status (NCT03002220) | MedSIR | 2016-12-21 |
| Collagen Cross-Linking With Ultraviolet-A in Asymmetric Corneas (NCT03029104) | Cxlusa | 2016-12-21 |
| Prophylactic DLI for the Prevention of Relapse Post HSCT in Patients With High Risk Myeloid Malignancy (NCT02856464) | King's College Hospital NHS Trust | 2016-12-21 |
| Effectiveness and Safety of SAR156597 in Treating Diffuse Systemic Sclerosis (NCT02921971) | Sanofi | 2016-12-21 |
| Study To Assess The Efficacy And Safety Of Pf-06651600 In Subjects With Rheumatoid Arthritis With An Inadequate Response To Methotrexate (NCT02969044) | Pfizer | 2016-12-20 |
| A Phase II Study of Atezolizumab in Combination With Cisplatin + Gemcitabine Before Surgery to Remove the Bladder Cancer (NCT02989584) | Memorial Sloan Kettering Cancer Center | 2016-12-20 |
| Safety And Efficacy Study Of Orally Administered Epeleuton In Patients With NAFLD (NCT02941549) | Afimmune | 2016-12-20 |
| Study of Y90-Radioembolization With Nivolumab in Asians With Hepatocellular Carcinoma (NCT03033446) | National Cancer Centre, Singapore | 2016-12-20 |
| Ibrutinib and Nivolumab in Treating Patients With Relapsed or Refractory Classical Hodgkin Lymphoma (NCT02940301) | Ohio State University Comprehensive Cancer Center | 2016-12-20 |
| An Open-Label Phase 1/2 Study of Itacitinib in Combination With Osimertinib in Subjects With Non-Small Cell Lung Cancer (NCT02917993) | Incyte Corporation | 2016-12-20 |
| Humacyte's HAV for Femoro-Popliteal Bypass in Patients With PAD (NCT02887859) | Humacyte, Inc. | 2016-12-20 |
| Study of Lemborexant for Irregular Sleep-Wake Rhythm Disorder and Mild to Moderate Alzheimer's Disease Dementia (NCT03001557) | Eisai Inc. | 2016-12-20 |
| A Study to Determine Safety, Feasibility and Efficacy of JCAR015 in Adult Subjects With B-Cell Acute Lymphoblastic Leukemia (NCT02973191) | Celgene | 2016-12-20 |
| Study of ProTmune for Allogeneic HCT in Adult Patients With Hematologic Malignancies (NCT02743351) | Fate Therapeutics | 2016-12-20 |
| Study of Pembrolizumab With or Without CC-486 in Patients With Platinum-resistant Ovarian Cancer (NCT02900560) | Translational Research in Oncology | 2016-12-20 |
| Injectable Cabotegravir Compared to TDF/FTC For PrEP in HIV-Uninfected Men and Transgender Women Who Have Sex With Men (NCT02720094) | National Institute of Allergy and Infectious Diseases (NIAID) | 2016-12-19 |
| TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma (NCT02663271) | University of Florida | 2016-12-19 |
| Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy (NCT02979873) | National Heart, Lung, and Blood Institute (NHLBI) | 2016-12-19 |
| Study of Avelumab With or Without Entinostat in Participants With Advanced Epithelial Ovarian Cancer (NCT02915523) | Syndax Pharmaceuticals | 2016-12-19 |
| Accelerated Radiation Therapy (ART) to the Breast and Nodal Stations (NCT02917421) | Weill Medical College of Cornell University | 2016-12-19 |
| A Novel Biologic Therapy for Perennial Allergic Rhinitis (NCT03360071) | Johns Hopkins University | 2016-12-19 |
| A Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid Tumors (NCT02983045) | Nektar Therapeutics | 2016-12-19 |
| Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Patients With Pulmonary Sarcoidosis (NCT02888080) | Novartis Pharmaceuticals | 2016-12-19 |
| Efficacy and Safety Trial With S 44819 After Recent Ischemic Cerebral Event (NCT02877615) | Institut de Recherches Internationales Servier | 2016-12-19 |
| Alcohol: Thiamine and or Magnesium 1 (NCT03466528) | Glasgow Royal Infirmary | 2016-12-16 |
| Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma (NCT02581930) | National Cancer Institute (NCI) | 2016-12-16 |
| Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid Leukemia (NCT02996474) | National Heart, Lung, and Blood Institute (NHLBI) | 2016-12-16 |
| Nivolumab and Radiation Therapy With or Without Ipilimumab in Treating Patients With Brain Metastases From Non-small Cell Lung Cancer (NCT02696993) | M.D. Anderson Cancer Center | 2016-12-16 |
| Ixazomib Rollover Study (NCT02924272) | Takeda | 2016-12-16 |
| Clinical Trial of Oral Ciprofloxacin and Etoposide in Subjects With Resistant Acute Myeloid Leukemia (AML)(UF-AML-CE-101) (NCT02773732) | University of Florida | 2016-12-16 |
| Phase 2a Study of PBTZ169 (NCT03334734) | Nearmedic Plus LLC | 2016-12-16 |
| Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCID (NCT02999984) | University of California, Los Angeles | 2016-12-16 |
| Deciphering Afatinib Response and Resistance With INtratumour Heterogeneity (NCT02183883) | University College, London | 2016-12-16 |
| A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of Venglustat (GZ/SAR402671) in Parkinson's Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation (NCT02906020) | Genzyme, a Sanofi Company | 2016-12-15 |
| Study To Evaluate The Efficacy And Safety Profile Of PF-06651600 And PF-06700841 In Subjects With Alopecia Areata (NCT02974868) | Pfizer | 2016-12-15 |
| A Study to Investigate Safety With Risankizumab in Psoriatic Arthritis Subjects Who Have Completed Week 24 Visit of Study M16-002 (NCT02719171) (NCT02986373) | AbbVie | 2016-12-15 |
| Efficacy of 595 nm Pulsed-dye Laser in Treatment of Discoid Lupus Erythematosus (NCT03178188) | Chulalongkorn University | 2016-12-15 |
| A 24-wk Dose Ranging Study to Evaluate the Efficacy and Safety of 4 Doses of a New PDE4 Inhibitor in Patients With COPD (NCT02986321) | Chiesi Farmaceutici S.p.A. | 2016-12-15 |
| An Open-label Extension Trial to Investigate Possible Drug-drug Interactions Between Stiripentol or Valproate and Cannabidiol in Patients With Epilepsy (NCT02607904) | Jazz Pharmaceuticals | 2016-12-15 |
| Andecaliximab as Add-On Therapy to a Tumor Necrosis Factor Inhibitor and Methotrexate Regimen in Adults With Moderately to Severely Active Rheumatoid Arthritis (NCT02862574) | Gilead Sciences | 2016-12-15 |
| Trial in Adult Participants With Spinocerebellar Ataxia (SCA) (NCT02960893) | Biohaven Pharmaceuticals, Inc. | 2016-12-15 |
| Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871 (NCT02971293) | AstraZeneca | 2016-12-15 |
| Ribociclib (LEE011) Rollover Study for Continued Access (NCT02934568) | Novartis Pharmaceuticals | 2016-12-15 |
| Durvalumab With or Without Tremelimumab in Metastatic Castration Resistant Prostate Cancer (NCT02788773) | Canadian Cancer Trials Group | 2016-12-15 |
| Tacrolimus After rATG and Infliximab Induction Immunosuppression (RIMINI) (NCT04114188) | Prof. Dr. Petra Reinke | 2016-12-15 |
| The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) Trial (NCT03182634) | Institute of Cancer Research, United Kingdom | 2016-12-15 |
| Durvalumab and Tremelimumab in Patients With Advanced Rare Tumours (NCT02879162) | Canadian Cancer Trials Group | 2016-12-14 |
| TG4010 and Nivolumab in Patients With Lung Cancer (NCT02823990) | Megan Daly, MD | 2016-12-14 |
| A Study of Mirikizumab (LY3074828) in Participants With Active Crohn's Disease (NCT02891226) | Eli Lilly and Company | 2016-12-14 |
| Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) Plus Temozolomide Versus Temozolomide Alone in Adults With Recurrent Anaplastic Astrocytoma and Glioblastoma (NCT02942264) | National Cancer Institute (NCI) | 2016-12-14 |
| A Study to Evaluate the Long-term Safety, Tolerability and Efficacy of Bimekizumab in Patients With Chronic Plaque Psoriasis (NCT03010527) | UCB Biopharma SRL | 2016-12-14 |
| Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated With Age-Related Macular Degeneration (NCT02564978) | National Eye Institute (NEI) | 2016-12-14 |
| Nivolumab With or Without Ipilimumab in Treating Patients With Gastrointestinal Stromal Tumor That Is Metastatic or Cannot Be Removed by Surgery (NCT02880020) | Jonsson Comprehensive Cancer Center | 2016-12-14 |
| Reduction by Pasireotide of the Effluent Volume in High-output Enterostomy in Patients Refractory to Usual Medical Treatment (NCT02713776) | Hospices Civils de Lyon | 2016-12-13 |
| ABC294640 (Opaganib) in Refractory / Relapsed Multiple Myeloma (NCT02757326) | RedHill Biopharma Limited | 2016-12-13 |
| A Study of ALN-PCSSC in Participants With Homozygous Familial Hypercholesterolemia (HoFH) (NCT02963311) | The Medicines Company | 2016-12-13 |
| Varlitinib in Combination With Gemcitabine and Cisplatin for Treatment naïve Advanced or Metastatic BTC (NCT02992340) | ASLAN Pharmaceuticals | 2016-12-13 |
| RICE-ibrutinib in Relapsed DLBCL (NCT02955628) | Singapore General Hospital | 2016-12-13 |
| Study to Evaluate the Safety and Efficacy of the Combination of Tirabrutinib and Idelalisib With and Without Obinutuzumab in Adults With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) (NCT02968563) | Gilead Sciences | 2016-12-13 |
| Atezolizumab as Induction Therapy in Non-small Cell Lung Cancer (NCT02994576) | Gustave Roussy, Cancer Campus, Grand Paris | 2016-12-12 |
| Effect and Safety of Local Injection of Botulinum Toxin Type B Against Digital Ulcer in Systemic Sclerosis (NCT03007004) | Gunma University | 2016-12-12 |
| Preoperative Chemoradiotherapy for Locally Advanced Resectable Gastric Adenocarcinoma (NCT03814759) | Yonsei University | 2016-12-12 |
| A Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Subjects With Progressive Supranuclear Palsy (PSP) (NCT02985879) | AbbVie | 2016-12-12 |
| Pembrolizumab + Lenalidomide Post Autologous Stem Cell Transplant (ASCT) in High-risk Multiple Myeloma (MM) (NCT02906332) | Hackensack Meridian Health | 2016-12-12 |
| Combination Chemotherapy With Nintedanib / Placebo in Endometrial Cancer (NCT02730416) | Nordic Society of Gynaecological Oncology - Clinical Trials Unit | 2016-12-12 |
| Impact of Duloxetine on Male Fertility (NCT03038867) | Weill Medical College of Cornell University | 2016-12-12 |
| Belinostat Therapy With Zidovudine for Adult T-Cell Leukemia-Lymphoma (NCT02737046) | University of Miami | 2016-12-12 |
| A Study to Evaluate the Efficacy, Safety and Tolerability of Fixed Doses of Intranasal Esketamine in Japanese Participants With Treatment Resistant Depression (NCT02918318) | Janssen Pharmaceutical K.K. | 2016-12-12 |
| The HeartSpare Plus 1B Trial (NCT02771353) | Royal Marsden NHS Foundation Trust | 2016-12-12 |
| A Phase II Clinical Study of LCB01-0371 to Evaluate the EBA, Safety and PK (NCT02836483) | LigaChem Biosciences, Inc. | 2016-12-10 |
| Clinical Trial to Evaluate the Efficacy and Safety of JPI-289 in Patients With Acute Ischemic Stroke (NCT03062397) | Jeil Pharmaceutical Co., Ltd. | 2016-12-09 |
| Pembrolizumab (MK-3475) in Hepatocellular Carcinoma (NCT02940496) | M.D. Anderson Cancer Center | 2016-12-09 |
| A Study of PTX-200 (Triciribine) Plus Cytarabine in Refractory or Relapsed Acute Leukemia (NCT02930109) | Prescient Therapeutics, Ltd. | 2016-12-09 |
| A Study to Evaluate the Efficacy and Safety of CT-P27 in Acute Uncomplicated Influenza A Infection (NCT03511066) | Celltrion | 2016-12-09 |
| Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma (NCT02910700) | M.D. Anderson Cancer Center | 2016-12-09 |
| A Study of Gemcitabine/Nab-paclitaxel and Radiation Therapy Followed by Surgery in Patients With Advanced Pancreatic Cancer (NCT02481635) | University Health Network, Toronto | 2016-12-08 |
| Phase 2 Study of Quizartinib in Participants With Acute Myeloid Leukemia (AML) FLT3 Internal Tandem Duplication (FLT3/ITD) Mutation (NCT02984995) | Daiichi Sankyo Co., Ltd. | 2016-12-08 |
| PEN-221 in Somatostatin Receptor 2 Expressing Advanced Cancers Including Neuroendocrine and Small Cell Lung Cancers (NCT02936323) | Tarveda Therapeutics | 2016-12-08 |
| 30000 IU Per Week Vitamin D Treatment in PCOS Patients (NCT04840238) | Semmelweis University | 2016-12-08 |
| Metformin With Neoadjuvant Chemoradiation to Improve Pathologic Responses in Rectal Cancer (NCT03053544) | Sunnybrook Health Sciences Centre | 2016-12-08 |
| Green Tea Extract for Endometriosis Treatment (NCT02832271) | Chinese University of Hong Kong | 2016-12-08 |
| Evaluating the Safety and Immunogenicity of HIV Clade C DNA Vaccine and MF59- or AS01B-Adjuvanted Clade C Env Protein Vaccines in Various Combinations in Healthy, HIV-Uninfected Adults (NCT02915016) | National Institute of Allergy and Infectious Diseases (NIAID) | 2016-12-07 |
| RIPE vs RIPE Plus N-acetylcysteine in Patients With HIV/TB Co-infection (NCT03281226) | Fundação de Medicina Tropical Dr. Heitor Vieira Dourado | 2016-12-07 |
| Study of PRO 140 SC as Single Agent Maintenance Therapy in Virally Suppressed Subjects With CCR5-tropic HIV-1 Infection (NCT02859961) | CytoDyn, Inc. | 2016-12-07 |
| Abbreviated 3 Cycles of Rituximab Plus CHOP(Cyclophosphamide, Adriamycin, Vincristine, and Prednisolone) Immunochemotherapy in Patients With Completely Excised LocalizedGastrointestinal CD(Cluster of Differentiation Antigen)20(+) Diffuse Large B-cell Lymphoma (NCT03399747) | Asan Medical Center | 2016-12-07 |
| Addition of X4P-001 to Nivolumab Treatment in Participants With Renal Cell Carcinoma (NCT02923531) | X4 Pharmaceuticals | 2016-12-07 |
| Trial of Anastrozole and Palbociclib in Metastatic HER2-Negative Breast Cancer (NCT02942355) | Wake Forest University Health Sciences | 2016-12-07 |
| Experimental Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 Anesthetic Spray in Normal Volunteers (NCT02908620) | Cetylite Industries | 2016-12-07 |
| A Study to Evaluate SAGE-217 in Participants With Moderate to Severe Major Depressive Disorder (NCT03000530) | Biogen | 2016-12-07 |