| Trial of Olaparib in Patients With Metastatic Urothelial Cancer Harboring DNA Damage Response Gene Alterations (NCT03448718) | Matthew Galsky | 2018-04-17 |
| Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial) (NCT03213652) | National Cancer Institute (NCI) | 2018-04-17 |
| Study to Assess Safety and Preliminary Activity of Eribulin Mesylate in Pediatric Participants With Relapsed/Refractory Rhabdomyosarcoma (RMS), Non-rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) and Ewing Sarcoma (EWS) (NCT03441360) | Eisai Inc. | 2018-04-17 |
| Safety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With Phenylketonuria (NCT03516487) | Synlogic | 2018-04-17 |
| Ezetimibe as a Safe and Efficacious Treatment for Chronic Hepatitis C (NCT02971033) | VA Office of Research and Development | 2018-04-16 |
| Safety and Efficacy of rAAV2tYF-GRK1-RPGR in Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations (NCT03316560) | Beacon Therapeutics | 2018-04-16 |
| Perioperative Ketamine for Pain With Gastric Bypass (NCT03448068) | Mayo Clinic | 2018-04-16 |
| Cabozantinib S-malate and Nivolumab in Treating Patients With Advanced, Recurrent, or Metastatic Endometrial Cancer (NCT03367741) | National Cancer Institute (NCI) | 2018-04-16 |
| A Phase 1/2 Study of FS118 in Patients With Advanced Malignancies (NCT03440437) | invoX Pharma Limited | 2018-04-16 |
| Sorafenib and Nivolumab in Treating Participants With Unresectable, Locally Advanced or Metastatic Liver Cancer (NCT03439891) | Robin Kate Kelley | 2018-04-16 |
| Evaluation of Effects of Estetrol on Testosterone Suppression and Quality of Life in Prostate Cancer Patients Treated With an LHRH Agonist. (NCT03361969) | Pantarhei Oncology B.V. | 2018-04-16 |
| Von Willebrand Factor Concentrate During ECMO Support (NCT03613584) | Tirol Kiniken GmbH | 2018-04-16 |
| Identification of a Biomarker Predictive of Evolution of Parkinson Disease (NCT03230526) | Nantes University Hospital | 2018-04-16 |
| A Randomized Study to Assess the Safety of GRF6019 Infusions in Subjects With Mild to Moderate Alzheimer's Disease (NCT03520998) | Alkahest, Inc. | 2018-04-16 |
| Assessing an Oral Janus Kinase Inhibitor, AZD4205, in Combination With Osimertinib in Patients Who Have Advanced Non-small Cell Lung Cancer (NCT03450330) | Dizal Pharmaceuticals | 2018-04-16 |
| Study of Spermatogenesis Suppression With DMAU Alone or With LNG Versus Placebo Alone in Normal Men (NCT03455075) | Premier Research | 2018-04-16 |
| Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Vaccine in Healthy Infants (NCT03512288) | Pfizer | 2018-04-16 |
| A Randomized Controlled Trial of Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD (NCT03339258) | San Francisco Veterans Affairs Medical Center | 2018-04-15 |
| FIRSTx - A Study of Oral CXA-10 in Primary Focal Segmental Glomerulosclerosis (FSGS) (NCT03422510) | Complexa, Inc. | 2018-04-15 |
| A Study Evaluating Bacillus Cereus in the Prevention of Afatinib-associated Diarrhea (NCT03486587) | Sun Yat-sen University | 2018-04-15 |
| Chidamide for Patients With Recurrent and Metastatic Epstein-Barr Virus (EBV)-Associated Solid Tumors (NCT03494634) | Sun Yat-sen University | 2018-04-15 |
| Cetuximab Plus FOLFOXIRI vs Cetuximab Plus FOLFOX For CRCLM (NCT03493048) | Sun Yat-sen University | 2018-04-15 |
| Study of BGB-A317 in Participants With Relapsed or Refractory Mature T- and NK-cell Neoplasms (NCT03493451) | BeiGene | 2018-04-13 |
| A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia (NCT03381287) | HighTide Therapeutics (Hong Kong) Limited | 2018-04-13 |
| Enzalutamide in Metastatic or Advanced Non-resectable Granulosa Cell Ovarian Tumors: GREKO III Study (NCT03464201) | Grupo Español de Tumores Huérfanos e Infrecuentes | 2018-04-13 |
| Study of Pancreatic Enzyme Replacement on Completion of Adjuvant Chemotherapy for Resected Pancreatic Adenocarcinoma (NCT03469258) | Dana-Farber Cancer Institute | 2018-04-13 |
| A Study of the Efficacy and Safety of Guselkumab in Participants With Moderately to Severely Active Crohn's Disease (NCT03466411) | Janssen Research & Development, LLC | 2018-04-13 |
| A Study to Evaluate Transplantation of Astrocytes Derived From Human Embryonic Stem Cells, in Patients With Amyotrophic Lateral Sclerosis (ALS) (NCT03482050) | Kadimastem | 2018-04-12 |
| Study of AKCEA-ANGPTL3-LRX (ISIS 703802) in Patients With Homozygous Familial Hypercholesterolemia (HoFH) (NCT03455777) | Akcea Therapeutics | 2018-04-12 |
| Durvalumab for MSI-H or POLE Mutated Metastatic Colorectal Cancer (NCT03435107) | Asan Medical Center | 2018-04-12 |
| Efficacy and Tolerability of IRL790 in Parkinson's Disease Dyskinesia (NCT03368170) | Integrative Research Laboratories AB | 2018-04-12 |
| Infusion of Umbilical Cord Versus Bone Marrow Derived Mesenchymal Stem Cells to Evaluate Cytokine Suppression. (NCT03059355) | Joshua M Hare | 2018-04-12 |
| Study of Melphalan Flufenamide (Melflufen) + Dex With Bortezomib or Daratumumab in Patients With RRMM (NCT03481556) | Oncopeptides AB | 2018-04-12 |
| Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors (NCT03507244) | The First Hospital of Jilin University | 2018-04-12 |
| Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Pancreatic Cancer (NCT03509298) | Fuda Cancer Hospital, Guangzhou | 2018-04-12 |
| Durvalumab Plus Tremelimumab Combined With Proton Therapy for HNSCC (NCT03450967) | Samsung Medical Center | 2018-04-11 |
| Nivolumab in Patients With Type B3 Thymoma and Thymic Carcinoma (NIVOTHYM) (NCT03134118) | European Organisation for Research and Treatment of Cancer - EORTC | 2018-04-11 |
| Intranasal Oxytocin vs. Placebo for the Treatment of Hyperphagia in Prader-Willi Syndrome (NCT03197662) | Eric Hollander | 2018-04-11 |
| Treat_CCM: Propranolol in Familial Cerebral Cavernous Malformation (NCT03589014) | Mario Negri Institute for Pharmacological Research | 2018-04-11 |
| A Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced Melanoma (NCT03470922) | Bristol-Myers Squibb | 2018-04-11 |
| Oral Decitabine and Tetrahydrouridine as Epigenetic Priming for Pembrolizumab-Mediated Immune Checkpoint Blockade in Patients With Inoperable, or Unresectable Locally Advanced or Metastatic Non-Small Cell Lung Cancers and Esophageal Carcinomas (NCT03233724) | National Cancer Institute (NCI) | 2018-04-11 |
| Ability of a Dendritic Cell Vaccine to Immunize Melanoma or Epithelial Cancer Patients Against Defined Mutated Neoantigens Expressed by the Autologous Cancer (NCT03300843) | National Cancer Institute (NCI) | 2018-04-11 |
| Open Label Study of ATI-50002 Topical Solution Administered to Adult Subjects With Eyebrow Loss Due to Alopecia Areata (NCT03551821) | Aclaris Therapeutics, Inc. | 2018-04-11 |
| Glucocorticoids and Skin Healing in Diabetes (GC-SHealD) (NCT03313297) | University of Leeds | 2018-04-10 |
| Efficacy and Safety Study of Navarixin (MK-7123) in Combination With Pembrolizumab (MK-3475) in Adults With Selected Advanced/Metastatic Solid Tumors (MK-7123-034) (NCT03473925) | Merck Sharp & Dohme LLC | 2018-04-10 |
| Phase 2 Study of TMX-049 in Subjects With Type 2 Diabetes and Albuminuria (NCT03449199) | Teijin America, Inc. | 2018-04-10 |
| Teh Effect of Subgingival Irrigation Wif Ketorolac and Chlorhexidine in Patients Wif Chronic Periodontist (NCT03836781) | Amirhossein Farahmand | 2018-04-10 |
| Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After Surgery (NCT04316039) | West China Hospital | 2018-04-10 |
| A Study of Prexasertib (LY2606368) in Platinum-Resistant or Refractory Recurrent Ovarian Cancer (NCT03414047) | Eli Lilly and Company | 2018-04-10 |
| Optimizing Chronic Low Back Pain Exercise Therapies With Cerebral Electrical Stimulation (NCT03503422) | Universidade Federal do Piauí | 2018-04-10 |
| Study of Brentuximab Vedotin in Patients With R/R PTCL Treated With Gemcitabine (NCT03496779) | The Lymphoma Academic Research Organisation | 2018-04-10 |
| Magnesium Sulphate Versus Fentanyl for Conscious Sedation in CSDH (NCT03548493) | Kasr El Aini Hospital | 2018-04-10 |
| A Study of UCB and MSCs in Children With CP: ACCeNT-CP (NCT03473301) | Joanne Kurtzberg, MD | 2018-04-10 |
| Accurate Dosimetry and Biomarkers Improve Survival in HCC Patients Treated With Resin 90 Yttrium (90Y)-Microspheres (NCT05227482) | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 2018-04-10 |
| Percutaneous Hepatic Perfusion vs. Cisplatin/Gemcitabine in Patients With Intrahepatic Cholangiocarcinoma (NCT03086993) | Delcath Systems Inc. | 2018-04-10 |
| Biomarkers of Response to Ipilimumab and Nivolumab in First-line NSCLC (NCT03425331) | Dana-Farber Cancer Institute | 2018-04-10 |
| Evaluation of Safety and Efficacy of Patients With Four and More Symptomatic Brain Metastases of Melanoma (NCT03728465) | University Hospital Tuebingen | 2018-04-10 |
| Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Kidney Cancer (NCT03540199) | Fuda Cancer Hospital, Guangzhou | 2018-04-10 |
| BIS-001-ER for the Treatment of Adult Focal Impaired Awareness Seizures (NCT03474770) | Supernus Pharmaceuticals, Inc. | 2018-04-10 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 in Adults With Congenital Adrenal Hyperplasia (NCT03525886) | Neurocrine Biosciences | 2018-04-10 |
| Hypertension, Intracranial Pulsatility and Brain Amyloid-beta Accumulation in Older Adults (HIPAC Trial) (NCT03354143) | University of Texas Southwestern Medical Center | 2018-04-10 |
| Fecal Microbial Transplantation and Fiber Supplementation in Participants With Obesity and Metabolic Syndrome. (NCT03477916) | University of Alberta | 2018-04-09 |
| Two Doses of Multimeric-001 (M-001) Followed by Influenza Vaccine (NCT03058692) | National Institute of Allergy and Infectious Diseases (NIAID) | 2018-04-09 |
| A Study of Toripalimab+ Pemetrexed Plus Carboplatin in Patients With EGFR-mutation Positive and T790M Negative After Progression on EGFR-TKI Treatment (NCT03513666) | Shanghai Junshi Bioscience Co., Ltd. | 2018-04-09 |
| Evaluation of N-Acetylcysteine Efficacy to Reduce the Craving and to Prolong Abstinence Time of Coca Paste (NCT03556371) | University of Concepcion, Chile | 2018-04-09 |
| Randomized, Placebo-Controlled Trial of N-acetylcysteine In Parkinson's Disease Patients: A Pilot Study (NCT07093944) | Kurdistan University of Medical Sciences | 2018-04-09 |
| Metoclopramide Versus Placebo for GJ Placement (NCT03331965) | Duke University | 2018-04-09 |
| Topical Endoxifen in Women (NCT04616430) | Atossa Therapeutics, Inc. | 2018-04-09 |
| Study of Tazemetostat in Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma With EZH2 Gene Mutation (NCT03456726) | Eisai Co., Ltd. | 2018-04-09 |
| Daratumumab in Treating Transplant-Eligible Patients With Multiple Myeloma (NCT03477539) | Mayo Clinic | 2018-04-09 |
| Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667) (NCT03407144) | Merck Sharp & Dohme LLC | 2018-04-09 |
| Polypharmacy-related Adverse Events in Critically Ill Children (NCT03293927) | Duke University | 2018-04-09 |
| Study of BGB-A317 in Participants With Previously Treated Unresectable HCC (NCT03419897) | BeiGene | 2018-04-09 |
| Study of Safety, Efficacy, Tolerability, Pharmacokinetics and Pharmacodynamics of LNP023 in in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) (NCT03439839) | Novartis Pharmaceuticals | 2018-04-09 |
| Comparative Efficacy of Duloxetine vs Escitalopram in Patients With Fibromyalgia (NCT03487211) | Shaheed Zulfiqar Ali Bhutto Medical University | 2018-04-09 |
| Efficacy and Safety Study of CNTO 2476 in Participants With Visual Acuity Impairment Associated With Geographic Atrophy (GA) Secondary to Age Related Macular Degeneration (AMD) (NCT02895815) | Janssen Pharmaceutical K.K. | 2018-04-09 |
| Preventing UTIs in Chronic Neurogenic Bladder Dysfunction (Mix Methods) (NCT02591901) | Buckinghamshire Healthcare NHS Trust | 2018-04-06 |
| Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-Suppressed Participants With Chronic Hepatitis B (NCT03491553) | Gilead Sciences | 2018-04-06 |
| A Study of Midostaurin Efficacy and Safety in Newly Diagnosed Patients With FLT3-mutated AML (NCT03280030) | Novartis Pharmaceuticals | 2018-04-06 |
| Topical Sodium Nitrite in Sickle Cell Disease and Leg Ulcers (NCT02863068) | caterina P minniti | 2018-04-06 |
| Ureter Identification With IRDye 800BK (NCT03387410) | Oxford University Hospitals NHS Trust | 2018-04-06 |
| Outpatient Administration of R-DHAP in Relapsed/Refractory Non-Hodgkin Lymphoma (NCT03892421) | La Raza Medical Center | 2018-04-05 |
| Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study) (NCT03407079) | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 2018-04-05 |
| Liver Transplantation for Early Intrahepatic Cholangiocarcinoma (NCT02878473) | University Health Network, Toronto | 2018-04-05 |
| Online HIV Prevention for Young Male Couples (NCT03284541) | Northwestern University | 2018-04-05 |
| Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Colorectal Cancer (NCT03524274) | Fuda Cancer Hospital, Guangzhou | 2018-04-05 |
| A Study to Assess the Effectiveness and Side Effects of GSK2798745 in Participants With Chronic Cough (NCT03372603) | GlaxoSmithKline | 2018-04-05 |
| Study to Evaluate Safety & Efficacy of FLX-787-ODT to Treat Fasciculations in Tongue and Appendicular Muscle in Adult Subjects With ALS (NCT03334786) | Flex Pharma, Inc. | 2018-04-05 |
| Study of Activated Cytokine-induced Killer Armed With Bispecific Antibody for Advanced Gastric Cancer (NCT03554395) | Fuda Cancer Hospital, Guangzhou | 2018-04-05 |
| A Study of Erdafitinib in Participants With Metastatic or Locally Advanced Urothelial Cancer (NCT03473743) | Janssen Research & Development, LLC | 2018-04-05 |
| Clinical Utility of Subcutaneous Furosemide in Patients Presenting With Early Signs of Fluid Overload (NCT03359161) | Steward St. Elizabeth's Medical Center of Boston, Inc. | 2018-04-05 |
| A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of M281 Administered to Pregnant Women at High Risk for Early Onset Severe Hemolytic Disease of the Fetus and Newborn (HDFN) (NCT03842189) | Janssen Research & Development, LLC | 2018-04-05 |
| Cariprazine Effects on Brain and Behavior in Cocaine Use Disorder (NCT03430544) | Anna Rose Childress, Ph.D. | 2018-04-04 |
| A Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy (NCT03406780) | Capricor Inc. | 2018-04-04 |
| PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of McCune-Albright Syndrome (NCT02743377) | National Institute of Mental Health (NIMH) | 2018-04-04 |
| Anti-chlamydophila Antibiotic Combination Therapy in the Treatment of Patients With Coronary Heart Disease (NCT03618108) | Cadrock Pty. Ltd. | 2018-04-04 |
| Utomilumab and ISA101b Vaccination in Patients With HPV-16-Positive Incurable Oropharyngeal Cancer (NCT03258008) | M.D. Anderson Cancer Center | 2018-04-04 |
| Study of GNS561 in Patients With Liver Cancer (NCT03316222) | Genoscience Pharma | 2018-04-04 |
| Evaluate the Effects and Safety of ALK4290 in Patients With Newly Diagnosed Wet Age-Related Macular Degeneration (NCT03558061) | Alkahest, Inc. | 2018-04-04 |
| Riluzole Oral Soluble Film (ROSF) Swallowing Safety in Amyotrophic Lateral Sclerosis (ALS) (NCT03679975) | Aquestive Therapeutics | 2018-04-04 |