| A Phase 1/2, Study Evaluating the Safety, Tolerability, PK, and Efficacy of Sotorasib (AMG 510) in Subjects With Solid Tumors With a Specific KRAS Mutation (CodeBreaK 100) (NCT03600883) | Amgen | 2018-08-27 |
| Durvalumab With or Without Tremelimumab in Resectable Locally Advanced Squamous Cell Carcinoma of the Oral Cavity (NCT03784066) | Universitaire Ziekenhuizen KU Leuven | 2018-08-27 |
| Pembrolizumab With Liver-Directed or Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors and Liver Metastases (NCT03457948) | Nicholas Fidelman, MD | 2018-08-27 |
| Talazoparib For Neoadjuvant Treatment Of Germline BRCA1/2 Mutation Patients With Early Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer (NCT03499353) | Pfizer | 2018-08-27 |
| Study to Test the Safety and Efficacy of Padsevonil as Adjunctive Treatment of Focal-onset Seizures in Adult Subjects With Drug-resistant Epilepsy (NCT03370120) | UCB Biopharma SRL | 2018-08-27 |
| Virtual Fitness Buddy Ecosystem (NCT03524183) | University of Georgia | 2018-08-27 |
| Study of Abexinostat in Patients With Relapsed or Refractory Follicular Lymphoma (NCT03600441) | Xynomic Pharmaceuticals, Inc. | 2018-08-27 |
| A Clinical Study to Assess the Efficacy and Safety of Dexamethasone Suspension for Cataract Surgery (NCT03687931) | iDrop, Inc. | 2018-08-26 |
| TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI) (NCT03477903) | Millennium Pharmaceuticals, Inc. | 2018-08-25 |
| Dragon III: Neoadjuvant Chemotherapy (FLOT Versus SOX) for Gastric Cancer (NCT03636893) | Ruijin Hospital | 2018-08-24 |
| EUS - Guided Balloon-occluded Gastrojejunostomy Bypass (NCT03223480) | Chinese University of Hong Kong | 2018-08-24 |
| Gentamicin Bladder Instillations to Prevent Urinary Tract Infections in Patients With Spinal Cord Injury (NCT03503513) | University of Michigan | 2018-08-24 |
| Pembrolizumab in Patients With Poor-Prognosis Carcinoma of Unknown Primary Site (CUP) (NCT03391973) | AHS Cancer Control Alberta | 2018-08-24 |
| Galunisertib and Capecitabine in Advanced Resistant TGF-beta Activated Colorectal Cancer (NCT03470350) | The Netherlands Cancer Institute | 2018-08-24 |
| Dexamethasone Added to Intensive Chemotherapy in Older Patients with Acute Myeloid Leukemia (AML) (NCT03609060) | French Innovative Leukemia Organisation | 2018-08-24 |
| Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic Castration Resistant Prostate Cancer With Homologous Recombination DNA Repair Deficiency (NCT03442556) | University of Washington | 2018-08-24 |
| ADCT-602 in Treating Patients With Recurrent or Refractory B-cell Acute Lymphoblastic Leukemia (NCT03698552) | M.D. Anderson Cancer Center | 2018-08-24 |
| Study of GLS-010 Injection in the Treatment of Classical Hodgkin's Lymphoma (NCT03655483) | Guangzhou Gloria Biosciences Co., Ltd. | 2018-08-24 |
| A Study to Evaluate SAGE-217 in Participants With Bipolar I/II Disorder With a Current Major Depressive Episode (NCT03692910) | Biogen | 2018-08-23 |
| Microbiological Evaluation of Single Versus Multiple Visits Regeneration Using MALDI-TOF Mass Spectrometry (NCT04533074) | Nourhan M.Aly | 2018-08-23 |
| CIRN Pneumococcal Conjugate Vaccine 1 vs. 2 Dose Priming Study (NCT03384589) | University of British Columbia | 2018-08-23 |
| PD-1 Antibody Combined With COX Inhibitor in MSI-H/dMMR or High TMB Colorectal Cancer (NCT03638297) | Sun Yat-sen University | 2018-08-23 |
| Memantine for the Treatment of Cognitive Impairment in Systemic Lupus Erythematosus (NCT03527472) | Vanderbilt University Medical Center | 2018-08-23 |
| Interventions Against Insulin Resistance in Pulmonary Arterial Hypertension (NCT03617458) | Vanderbilt University Medical Center | 2018-08-23 |
| EG-501 for Cognitive Impairment in Neuropsychiatric SLE (NPSLE): Efficacy and Safety Study (NCT07281105) | Evergreen Therapeutics, Inc. | 2018-08-23 |
| Laparoscopic Versus Open Gastrectomy for Elderly Local Advanced Gastric Cancer Patients (NCT03564834) | Peking University | 2018-08-23 |
| Phase I/II Study of Hydroxychloroquine With Itraconazole With Biochemically Recurrent Prostate Cancer (NCT03513211) | St Vincent's Hospital, Sydney | 2018-08-23 |
| A Clinical Study of AL2846 Capsule Combined With Gemzar Injection in the Treatment of Advanced Pancreatic Cancer (NCT06278493) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2018-08-23 |
| Copanlisib With Ibrutinib for Patients With Recurrent/ Refractory Primary Central Nervous System Lymphoma (PCNSL) (NCT03581942) | Memorial Sloan Kettering Cancer Center | 2018-08-23 |
| Preventing Stroke Triggers in Children With Sickle Cell Anaemia in Mulago Hospital, Kampala (PREST ): a Randomized Control Trial (NCT03666806) | Makerere University | 2018-08-22 |
| Niraparib in Patients With Pancreatic Cancer (NCT03601923) | Dana-Farber Cancer Institute | 2018-08-22 |
| Guilingji Capsule for Mild-to-moderate Cognitive Impairment (NCT03647384) | Xiyuan Hospital of China Academy of Chinese Medical Sciences | 2018-08-22 |
| ATOP TRIAL: T-DM1 in HER2 Positive Breast Cancer (NCT03587740) | Dana-Farber Cancer Institute | 2018-08-22 |
| IO102 With Pembrolizumab, With or Without Chemotherapy, as First-line Treatment of Metastatic NSCLC (NCT03562871) | IO Biotech | 2018-08-22 |
| The Efficacy and Neurobehavioural Mechanism of N-acetyl Cysteine (NAC) for Alcohol Dependence (NCT03879759) | South West Sydney Local Health District | 2018-08-22 |
| A First-in-human, Proof of Concept Study of CPK850 in Patients With RLBP1 Retinitis Pigmentosa (NCT03374657) | Novartis Pharmaceuticals | 2018-08-22 |
| Rifaximin to Modify the Disease Course in Sickle Cell Disease (NCT03719729) | New York Medical College | 2018-08-22 |
| KN035 for dMMR/MSI-H Advanced Solid Tumors (NCT03667170) | 3D Medicines (Sichuan) Co., Ltd. | 2018-08-22 |
| Safety, Tolerability and Long-term Immunogenicity of Different Formulations of a Chikungunya Vaccine (V184-005) (NCT03635086) | Themis Bioscience GmbH | 2018-08-22 |
| Evaluating Cancer Response to Treatment With Abemaciclib and Fulvestrant in Women With Recurrent Endometrial Cancer (NCT03643510) | Memorial Sloan Kettering Cancer Center | 2018-08-21 |
| Study Assessing PTI-428 Safety, Tolerability, Pharmacokinetics and Effect in Subjects With Cystic Fibrosis (NCT03591094) | Proteostasis Therapeutics, Inc. | 2018-08-21 |
| 2013/2017 H7N9 Prime-Boost Interval (NCT03589807) | National Institute of Allergy and Infectious Diseases (NIAID) | 2018-08-21 |
| Venetoclax and Romidepsin in Treating Patients With Recurrent or Refractory Mature T-Cell Lymphoma (NCT03534180) | City of Hope Medical Center | 2018-08-21 |
| PK,PD,Safety and Tolerability of Multiple Dose Regimens of MT-3724 With Gemcitabine and Oxaliplatin for the Treatment of Patients With Relapsed/Refractory Diffuse Large B Cell Non-Hodgkin's Lymphoma (NCT03488251) | Molecular Templates, Inc. | 2018-08-20 |
| Testing JNJ-42756493 (Erdafitinib) as Potentially Targeting Treatment in Cancers With FGFR Amplifications (MATCH-Subprotocol K1) (NCT06308822) | National Cancer Institute (NCI) | 2018-08-20 |
| Dried Leaf Artemisia (DLA) Compared to Artemisinin Combination Therapy (ACT) vs Malaria (NCT03199755) | Worcester Polytechnic Institute | 2018-08-20 |
| Brexpiprazole for the Treatment of Patients With Agitation Associated With Dementia of the Alzheimer's Type (NCT03620981) | Otsuka Pharmaceutical Co., Ltd. | 2018-08-20 |
| Effect of Olmesartan and Nebivolol on Ambulatory Blood Pressure and Arterial Stiffness in Acute Stage of Ischemic Stroke (NCT03655964) | Aristotle University Of Thessaloniki | 2018-08-20 |
| Effects of Simvastatin on Uterine Leiomyoma Size (NCT03400826) | Johns Hopkins University | 2018-08-20 |
| Neoadjuvant Chemoradiation Plus PD-1 Antibody(SHR-1210) in Locally Advanced Proximal Stomach Adenocarcinoma (NCT03631615) | Shanghai Zhongshan Hospital | 2018-08-20 |
| Acetaminophen Versus IV Hydromorphone for Pain in the Elderly in the ED (NCT03521102) | Montefiore Medical Center | 2018-08-20 |
| Study of the Interest of Pursuing or Not the Chemotherapy for Patients With Metastatic Esophageal Cancer (NCT03301454) | Centre Oscar Lambret | 2018-08-20 |
| Ursodeoxycholic Acid (UDCA) for Hepatic Sarcoidosis (NCT03602976) | Ethan Weinberg | 2018-08-20 |
| Paracetamol and Neuropathic Pain (NCT03559985) | University Hospital, Clermont-Ferrand | 2018-08-20 |
| Heparin Intraoperative Instillation for Lower Urinary Tract Symptoms After Benign Hysterectomy (NCT03633994) | The Christ Hospital | 2018-08-20 |
| A Pilot Study of 5-AZA and ATRA for Prostate Cancer With PSA-only Recurrence After Local Treatment (NCT03572387) | Icahn School of Medicine at Mount Sinai | 2018-08-20 |
| Efficacy and Safety of 0.25% Timolol Gel in Healing Surgical Open Wounds (NCT03452072) | Brigham and Women's Hospital | 2018-08-20 |
| Hydroxychloroquine, Palbociclib, and Letrozole Before Surgery in Treating Patients With Estrogen Receptor Positive, HER2 Negative Breast Cancer (NCT03774472) | M.D. Anderson Cancer Center | 2018-08-20 |
| Use of Low-dose Zolpidem in Parkinson's Disease (NCT03621046) | Aston University | 2018-08-20 |
| Postoperative Concurrent Chemoradiotherapy Versus Radiotherapy Alone for Patients With Locoregionally Advanced Esophageal Squamous Cell Carcinoma (NCT03600831) | Huai'an First People's Hospital | 2018-08-20 |
| Piroxicam and Levonorgestrel Co-treatment for Emergency Contraception (NCT03614494) | Dr. Hang Wun Raymond Li | 2018-08-20 |
| Mesenchymal Stem Cell Therapy for Liver Cirrhosis (NCT03626090) | Stem Med Pte. Ltd. | 2018-08-18 |
| The Combination of Donepezil and Cognitive Training for Treating Alcohol Use Disorder (NCT04318639) | VA Connecticut Healthcare System | 2018-08-17 |
| A Proof of Concept Pilot Trial of Alpha-1-Antitrypsin for Pre-Emption Of Steroid-Refractory Acute GVHD (NCT03459040) | John Levine | 2018-08-17 |
| Effect of L-Dihydroxyphenylserine (L-DOPS) on Falls in Patients With Neurogenic Orthostatic Hypotension (NOH) (NCT03567447) | St. Joseph's Hospital and Medical Center, Phoenix | 2018-08-17 |
| PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without mGluR Mutations (NCT03609619) | Aevi Genomic Medicine, LLC, a Cerecor company | 2018-08-17 |
| Riociguat in Patients With Operable CTEPH Prior to Pulmonary Endarterectomy (PEA Bridging Study) (NCT03273257) | International CTEPH Association | 2018-08-17 |
| LIPIDS-P Trial Phase I/II Trial (NCT03405870) | University of Florida | 2018-08-17 |
| Ixazomib, Gemcitabine, and Doxorubicin in Treating Patients With Locally Advanced or Metastatic Kidney Cancer (NCT03587662) | M.D. Anderson Cancer Center | 2018-08-17 |
| Lipoic Acid for Progressive Multiple Sclerosis (MS) (NCT03161028) | VA Office of Research and Development | 2018-08-17 |
| Study to Assess the Long-term Safety of Lenvatinib Monotherapy, a Lenvatinib Combination Regimen, or a Comparator Treatment Arm to Cancer Participants in Eisai Sponsored Lenvatinib Trials (NCT03477175) | Eisai Inc. | 2018-08-16 |
| Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway. (NCT03363217) | St. Justine's Hospital | 2018-08-16 |
| A Phase IIa Study to Assess the Safety, Efficacy, and Pharmacokinetics of Subcutaneously Administered Pegcetacoplan (APL-2) in Subjects With PNH (NCT03593200) | Apellis Pharmaceuticals, Inc. | 2018-08-16 |
| ET-01 in Subjects With Lateral Canthal Lines, LCL-207 (NCT03655691) | Eirion Therapeutics Inc. | 2018-08-16 |
| Vitamin D and Arterial Stiffness in Elderly (NCT03649802) | Texas Tech University Health Sciences Center | 2018-08-16 |
| Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood (NCT03793478) | Daiichi Sankyo | 2018-08-15 |
| Feasibility & Efficacy of Durvalumab+Tremelimumab+RT and Durvalumab+RT in Non-resect. Locally Advanced HPVnegativ HNSCC (NCT03624231) | Ulrich Keilholz | 2018-08-15 |
| Study of Anlotinib Plus Chemotherapy as the First-line Treatment in Patients With Advanced NSCLC (NCT03636685) | Chinese Academy of Medical Sciences | 2018-08-15 |
| Phase II Study of NGC-Triple Regimen in Potentially Resectable Pancreatic Cancer Patients (NCT03392571) | Pancreatic Cancer Research Team | 2018-08-15 |
| Reducing Hippocampal Hyperactivity and Improving Cognition in Schizophrenia (NCT03034356) | VA Office of Research and Development | 2018-08-15 |
| Oral Arsenic Trioxide for Newly Diagnosed Acute Promyelocytic Leukaemia (NCT03624270) | The University of Hong Kong | 2018-08-15 |
| Oral Amantadine, IV Amantadine and Hemodynamic Response to Laryngoscopy (NCT03612921) | Assiut University | 2018-08-15 |
| The Effect of Triheptanoin on Fatty Acid Oxidation and Exercise Tolerance in Patients With Glycogenoses (NCT03642860) | Rigshospitalet, Denmark | 2018-08-15 |
| Evaluation of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease (NCT03636061) | Oyster Point Pharma, Inc. | 2018-08-15 |
| Analgesic Efficacy of Pulsed Radiofrequency in Non-cyclic Mastalgia (NCT03715413) | Mansoura University | 2018-08-15 |
| Palbociclib and Letrozole or Fulvestrant in Treating Patients With Estrogen Receptor Positive, HER2 Negative Metastatic Breast Cancer (NCT03633331) | Alliance for Clinical Trials in Oncology | 2018-08-15 |
| Evaluation of the Long Term Follow up of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease (NCT03920215) | Oyster Point Pharma, Inc. | 2018-08-15 |
| A Study to Evaluate the Safety, Tolerability and Efficacy of ILB in Patients With Amyotrophic Lateral Sclerosis (NCT03613571) | TikoMed AB | 2018-08-15 |
| TEW-7197 with Paclitaxel for the Treatment of Metastatic Gastric Cancer (NCT03698825) | MedPacto, Inc. | 2018-08-15 |
| Combinatory ImmunoTherapy-1 (Com-IT-1) Irradiation and PD-1 Blockade in Locally Advanced / Advanced NSCLC (NCT03644823) | Oslo University Hospital | 2018-08-15 |
| Fentanyl Versus Midazolam as an Adjunct to Intrathecal Bupivacaine In Children (NCT03592537) | Assiut University | 2018-08-15 |
| Hydroxychloroquine in Individuals At-risk for Type 1 Diabetes Mellitus (NCT03428945) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2018-08-15 |
| A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy (NCT03391479) | University Health Network, Toronto | 2018-08-15 |
| Cytoreductive Prostatectomy Versus Cytoreductive Prostate Irradiation As a Local Treatment Option for Metastatic Prostate Cancer: a Multicentric Feasibility Trial (NCT03655886) | University Hospital, Ghent | 2018-08-15 |
| A Study of Avelumab, Binimetinib and Talazoparib in Patients With Locally Advanced or Metastatic RAS-mutant Solid Tumors (NCT03637491) | Pfizer | 2018-08-15 |
| Soy Bread Diet in Improving Immune Function in Participants With Prostate Cancer (NCT03654638) | Ohio State University Comprehensive Cancer Center | 2018-08-15 |
| Ibrutinib and Ixazomib Citrate in Treating Newly Diagnosed, Relapsed or Refractory Waldenstrom Macroglobulinemia (NCT03506373) | Mayo Clinic | 2018-08-14 |
| Diagnostic Validity of [18F]FSPG PET for the Assessment of Disease Activity in Inflammatory Bowel Disease (NCT03546868) | Asan Foundation | 2018-08-14 |
| Onvansertib in Combination With Abiraterone and Prednisone in Adult Patients With Metastatic Castration-Resistant Prostate Cancer (NCT03414034) | Cardiff Oncology | 2018-08-14 |
| A Study to Assess Efficacy and Safety of GLPG1972/S201086 in Participants With Knee Osteoarthritis (NCT03595618) | Lakefront Biotherapeutics NV | 2018-08-14 |