| Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Combination With Ibuprofen for Closure of the Ductus Arteriosus (NCT03701074) | University of South Alabama | 2018-12-15 |
| Efficacy and Safety of Trastuzumab Biosimilar (Herzuma®) Plus Treatment of Physician's Choice (TPC) in Patients With HER-2 Positive Metastatic Breast Cancer (NCT03755141) | National Cancer Center, Korea | 2018-12-15 |
| Open Label Study of IV Brincidofovir in Adult Transplant Recipients With Adenovirus Viremia (NCT03532035) | Jazz Pharmaceuticals | 2018-12-15 |
| Trial of Oral Hyaluronic Acid for the Prevention of Aromatase Inhibitor-Associated Arthralgias (NCT03384095) | Erin Newton | 2018-12-14 |
| MRI-guided Focal Laser Ablation (NCT04379362) | Radboud University Medical Center | 2018-12-14 |
| A Multi-center, Single-arm, Open, Phase I/IIa Clinical Trial to Evaluate the Efficacy and Safety of EBViNT Cell (EBV Specific Autologous CD8+ T Cell) in Patients With Treatment Failed Epstein Barr Virus (EBV)-Positive Malignancies (NCT03789617) | Eutilex | 2018-12-14 |
| A Window of Opportunity Trial: Avelumab in Non-metastatic Muscle Invasive Bladder Cancer (NCT03498196) | Baylor College of Medicine | 2018-12-14 |
| Atezolizumab After Chemo-radiotherapy for MIBC Patients Not Eligible for Radical Cystectomy (NCT03697850) | UNICANCER | 2018-12-14 |
| Impact of Combined Medication and Behavioral Treatment for ASD & ADHD (NCT03242772) | Duke University | 2018-12-14 |
| A Study Of AL101In Patients With Adenoid Cystic Carcinoma (ACC) Bearing Activating Notch Mutations (NCT03691207) | Ayala Pharmaceuticals, Inc, | 2018-12-14 |
| Immunotherapy in Patients With Metastatic Cancers and CDK12 Mutations (NCT03570619) | University of Michigan Rogel Cancer Center | 2018-12-14 |
| Comparison of the Efficacy & Safety of Resusix With FP24 in Patients With Acquired Coagulopathy (NCT03700723) | Entegrion, Inc. | 2018-12-14 |
| Tegio Consolidation Therapy for NPC Patients With High Risk of Metastasis (NCT03904225) | Zhejiang Cancer Hospital | 2018-12-14 |
| Irinotecan-based Triplet (FOLFOXIRI) as Perioperative Treatment in Resectable Gastric and Gastroesophageal Junction Adenocarcinoma. (NCT03773367) | Lund University Hospital | 2018-12-14 |
| Management of Cardiovascular Disease in Kidney Disease (MaCK) Study (NCT03636152) | VA Office of Research and Development | 2018-12-14 |
| A Study to Assess Efficacy and Safety Intravenous Benapenem in Patients With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) (NCT04505683) | Sihuan Pharmaceutical Holdings Group Ltd. | 2018-12-13 |
| Fecal Microbiota Transplantation for Steroid Resistant/Dependent Acute GI GVHD (NCT03812705) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2018-12-13 |
| Intratumoral Cavrotolimod Combined With Pembrolizumab or Cemiplimab in Patients With Merkel Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, or Other Advanced Solid Tumors (NCT03684785) | Exicure, Inc. | 2018-12-13 |
| A Dose Escalation With Expansion Study of EMB-01 in Participants With Advanced/Metastatic Solid Tumors (NCT03797391) | Shanghai EpimAb Biotherapeutics Co., Ltd. | 2018-12-13 |
| Avelumab and Radiation in Muscle-Invasive Bladder Cancer (NCT03747419) | Dana-Farber Cancer Institute | 2018-12-13 |
| Anti-Schistosomiasis Vaccine: Sm14 Phase 2b-Sn in School Children (NCT03799510) | Oswaldo Cruz Foundation | 2018-12-13 |
| BR55 in Characterization of Ovarian Lesions (NCT03493464) | Bracco Diagnostics, Inc | 2018-12-13 |
| An Efficacy and Safety Study of bb2121 in Subjects With Relapsed and Refractory Multiple Myeloma and in Subjects With High-Risk Multiple Myeloma (NCT03601078) | Celgene | 2018-12-13 |
| A Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases (NCT03625141) | Hoffmann-La Roche | 2018-12-13 |
| The Relationship Between Neuropsychological Testing and MRI, PET and COBRE - Project 1: AIM 2 (GE-180) (NCT03702816) | Aaron Ritter, MD | 2018-12-13 |
| Study of AGB101 in Mild Cognitive Impairment Due to Alzheimer's Disease (NCT03486938) | AgeneBio | 2018-12-13 |
| A Study of KY1005 in Patients With Moderate to Severe Atopic Dermatitis (NCT03754309) | Kymab Limited | 2018-12-13 |
| A Study of the Safety and Activity of Liposomal Irinotecan in Combination With the 5-FU and Oxaliplatin in the Preoperative Treatment of Pancreatic Adenocarcinoma (NCT03483038) | University of Florida | 2018-12-13 |
| Near-Infrared Image Guided Surgical Resection With Indocyanine Green in Treating Patients With Head and Neck Cancer (NCT03745690) | Jonsson Comprehensive Cancer Center | 2018-12-12 |
| Donor Cellular Therapy After Cytarabine in Treating Patients With Intermediate-Risk Acute Myeloid Leukemia in Remission (NCT02587871) | University of Southern California | 2018-12-12 |
| Phase 2 Study of Pembrolizumab+Carboplatin in Breast Related Cancer Antigens-related Metastatic Breast Cancer (PEMBRACA) (NCT03732391) | CORTESI LAURA | 2018-12-12 |
| A Dose-ranging Study to Evaluate Efficacy and Safety of VX-150 in Subjects With Acute Pain Following Bunionectomy (NCT03764072) | Vertex Pharmaceuticals Incorporated | 2018-12-12 |
| Transplanting Hepatitis C Lungs Into Negative Lung Recipients (NCT03724149) | University of Pennsylvania | 2018-12-12 |
| AMTEC IIT: Phase 2 Multiarm Study in TNBC (NCT03801369) | Gordon Mills, MD, PhD | 2018-12-12 |
| Efficacy and Safety of Olaparib (MK-7339) in Participants With Previously Treated, Homologous Recombination Repair Mutation (HRRm) or Homologous Recombination Deficiency (HRD) Positive Advanced Cancer (MK-7339-002 / LYNK-002) (NCT03742895) | Merck Sharp & Dohme LLC | 2018-12-12 |
| Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17 (NCT03755804) | St. Jude Children's Research Hospital | 2018-12-12 |
| Androgen Deprivation Therapy Combined With Docetaxel for High Risk Prostate Cancer (NCT04869371) | Hongqian Guo | 2018-12-12 |
| Tolvaptan-Octreotide LAR Combination in ADPKD (NCT03541447) | Mario Negri Institute for Pharmacological Research | 2018-12-12 |
| Ifetroban in Treating Patients With Malignant Solid Tumors at High Risk of Metastatic Recurrence (NCT03694249) | Vanderbilt-Ingram Cancer Center | 2018-12-12 |
| The HIV Functional Cure Potential of UB-421 in ART Stabilized HIV-1 Patients (NCT03743376) | United BioPharma | 2018-12-12 |
| Tenofovir/Levonorgestrel Intravaginal Ring and Tenofovir Intravaginal Ring (NCT03762382) | CONRAD | 2018-12-12 |
| Efficacy and Safety of DaxibotulinumtoxinA for Injection for the Treatment of Adult Upper Limb Spasticity (NCT03821402) | Revance Therapeutics, Inc. | 2018-12-12 |
| A Study of CMV Vaccine (HB-101) in Kidney Transplant Patients (NCT03629080) | Hookipa Biotech GmbH | 2018-12-12 |
| Prostate Cancer Monitoring Using [18F]DCFPyL and Blood Based Biomarkers (NCT03585114) | Columbia University | 2018-12-11 |
| 131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastases (NCT03275402) | Y-mAbs Therapeutics | 2018-12-11 |
| Safety and Tolerability Study of AZD4831 in Patients With Heart Failure. (NCT03756285) | AstraZeneca | 2018-12-11 |
| TACE Plus PD-1 Antibody vs TACE Alone for Unresectable HCC (NCT03782831) | Sun Yat-sen University | 2018-12-11 |
| QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors (NCT03228667) | ImmunityBio, Inc. | 2018-12-11 |
| A Study of Isatuximab-based Therapy in Participants With Lymphoma (NCT03769181) | Sanofi | 2018-12-11 |
| Probiotics to Prevent Relapse After Hospitalization for Bipolar Depression (NCT03349528) | Sheppard Pratt Health System | 2018-12-11 |
| Efficacy and Safety of Ucha-Shinki-Hwan on Korean Patients With Cold Hypersensitivity in the Hands and Feet-Double Blinded, Randomized, Multicenter, Placebo Controlled Clinical Trial (NCT03790033) | Gachon University Gil Oriental Medical Hospital | 2018-12-11 |
| A Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Relapsing Forms of Multiple Sclerosis (NCT03737851) | AbbVie | 2018-12-11 |
| Study in Patients With Chronic Leukemia (NCT03807479) | GWT-TUD GmbH | 2018-12-11 |
| Study of Efficacy of PEAR-004 in Schizophrenia (NCT03751280) | Novartis Pharmaceuticals | 2018-12-10 |
| VAccination in Early and ADvanced Prostate caNCEr (NCT03815942) | University of Oxford | 2018-12-10 |
| Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations (NCT03609216) | Alliance for Clinical Trials in Oncology | 2018-12-10 |
| Pharmacokinetics and Dynamics of Nebulized Dexmedetomidine (NCT03762785) | Assiut University | 2018-12-10 |
| FOcal Radiation for Oligometastatic Castration-rEsistant Prostate Cancer (FORCE) (NCT03556904) | University of Michigan Rogel Cancer Center | 2018-12-10 |
| Study Evaluating 5 Doses of RPL554 and Placebo in COPD Patients Via a Dry Powder Inhaler (NCT04027439) | Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA | 2018-12-10 |
| Orally Administered ENT-01 for Parkinson's Disease-Related Constipation (KARMET) (NCT03781791) | Enterin Inc. | 2018-12-10 |
| Weekly Single Fraction Hypofractionated Adjuvant Radiotherapy for Early Stage Breast Cancer (NCT04580784) | Mona Salem | 2018-12-10 |
| Cholinergic Urticaria - Efficacy of Dupilumab (NCT03749148) | Charite University, Berlin, Germany | 2018-12-10 |
| Pre-emptive Daratumumab Therapy of Minimal Residual Disease Reappearance or Biochemical Relapse in Multiple Myeloma (NCT03697655) | Polish Myeloma Consortium | 2018-12-10 |
| Voronistat in Pediatric Patients With Drug Resistant Epilepsy (NCT03894826) | University of Calgary | 2018-12-10 |
| A Modular Multi-Basket Trial to Improve Personalized Medicine in Cancer Patients (Basket of Baskets) (NCT03767075) | Vall d'Hebron Institute of Oncology | 2018-12-10 |
| Dexmedetomidine and Pregabalin for Conscious Sedation During Cataract Surgery (NCT03735368) | Abd-Elazeem Abd-Elhameed Elbakry | 2018-12-10 |
| A Follow up Study to Protocol 101/2 - Continued Treatment by IPL344 IV (NCT03755167) | Immunity Pharma Ltd. | 2018-12-09 |
| Functional Microscale Organotypic Assays to Predict Patient Response to Anti-Angiogenesis Therapies (NCT03387514) | University of Wisconsin, Madison | 2018-12-08 |
| A Long Term Study to Find Out if Macitentan is an Effective and Safe Treatment for Patients With Heart Failure With Preserved Ejection Fraction and Pulmonary Vascular Disease (NCT03714815) | Actelion | 2018-12-07 |
| Evaluation of the Safety and Efficacy of ALS-L1023 Administered in Combination With Ranibizumab in Patients With Wet-AMD (NCT03725501) | AngioLab, Inc. | 2018-12-07 |
| Botulinum for Chronic Exertional Compartment Syndrome (NCT03339921) | 375th Medical Group, Scott Air Force Base | 2018-12-07 |
| HEPLISAV-B Hepatitis B Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's-Tyrosine Kinase Inhibitor (BTK-I) (NCT03685708) | National Heart, Lung, and Blood Institute (NHLBI) | 2018-12-07 |
| An Active and Placebo-Controlled Study of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease (NCT03759288) | AstraZeneca | 2018-12-07 |
| Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) and CLL Treated With Bruton's Tyrosine Kinase Inhibitor (BTK-I) (NCT03702231) | National Heart, Lung, and Blood Institute (NHLBI) | 2018-12-07 |
| Selected Mesenchymal Stromal Cells to Reduce Inflammation in Patients With PSC and AIH (NCT02997878) | University of Birmingham | 2018-12-07 |
| SAD and MAD of Inhaled AR-501 in Health Adults and P. Aeruginosa Infected Cystic Fibrosis Subjects (NCT03669614) | Aridis Pharmaceuticals, Inc. | 2018-12-07 |
| Translating Neuroprediction Into Precision Medicine Via Brain Priming (NCT03370510) | Yale University | 2018-12-07 |
| Study of Dutogliptin in Combination With Filgrastim in Post-Myocardial Infarction (NCT03486080) | Recardio, Inc. | 2018-12-07 |
| Adavosertib With or Without Olaparib in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer (NCT03579316) | M.D. Anderson Cancer Center | 2018-12-07 |
| CPI-613 in Combination With Modified FOLFIRINOX in Locally Advanced Pancreatic Cancer (NCT03699319) | David Bajor, MD | 2018-12-07 |
| 5-HTP in Patients With IBD in Clinical and Biologic Remission:Effect on Fatigue Scores (NCT03574948) | University Hospital, Ghent | 2018-12-06 |
| Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapy (NCT03670056) | Yale University | 2018-12-06 |
| Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects With Complicated Skin and Soft Tissue Infections (cSSTI) and Bacteremia (MK-3009-029) (NCT03643952) | Merck Sharp & Dohme LLC | 2018-12-06 |
| T-DM1 and Palbociclib for Metastatic HER2 Breast Cancer (NCT03530696) | University of Arizona | 2018-12-06 |
| Efficacy and Safety of Anlotinib Plus Platinum Plus Pemetrexed in T790M-negative NSCLC (NCT03706287) | Sichuan Cancer Hospital and Research Institute | 2018-12-06 |
| NEoadjuvant Dose-dense MVAC In cOmbination With Durvalumab and Tremelimumab in Muscle-invasive Urothelial Carcinoma (NCT03549715) | Association Pour La Recherche des Thérapeutiques Innovantes en Cancérologie | 2018-12-06 |
| Evaluating an Amino Acid Based Medical Food w/ Diarrhea in Carcinoid Syndrome & Other NETs (NCT03722511) | Lowell Anthony, MD | 2018-12-06 |
| Brigatinib in Relapsed or Refractory ALK-Positive Anaplastic Large Cell Lymphoma (NCT03719898) | Fox Chase Cancer Center | 2018-12-06 |
| Treating Inflammation in Polycystic Ovary Syndrome to Ameliorate Ovarian Dysfunction (NCT03229408) | University of Illinois at Chicago | 2018-12-05 |
| Effects of Nitric Oxide on the Endothelium During Hemolysis. (NCT03748082) | Massachusetts General Hospital | 2018-12-05 |
| Montelukast for Prevention & Treatment of OHSS (NCT03794037) | Benha University | 2018-12-05 |
| A Randomized, Double-blind, Placebo-controlled Study of Delandistrogene Moxeparvovec (SRP-9001) for Duchenne Muscular Dystrophy (DMD) (NCT03769116) | Sarepta Therapeutics, Inc. | 2018-12-05 |
| Trial of IRE in Cholangiocarcinoma (NCT03769753) | Memorial Sloan Kettering Cancer Center | 2018-12-05 |
| Trial of Combination Tumor Treating Fields (TTF; Optune), Nivolumab Plus/Minus Ipilimumab for Recurrent Glioblastoma (NCT03430791) | Baptist Health South Florida | 2018-12-05 |
| Trial of Mitomycin C During Nephroureterectomy for Urothelial Carcinoma (NCT03658304) | University of Florida | 2018-12-05 |
| Intraarterial Alteplase Versus Placebo After Mechanical Thrombectomy (NCT03876119) | Hospital Clinic of Barcelona | 2018-12-05 |
| A Feasibility and Safety Study of Dual Specificity CD38 and BCMA CAR-T Cell Immunotherapy for Relapsed or Refractory Multiple Myeloma (NCT03767751) | Chinese PLA General Hospital | 2018-12-05 |
| Safety and Efficacy of Nivolumab in Treating Oral Proliferative Verrucous Leukoplakia (NCT03692325) | Dana-Farber Cancer Institute | 2018-12-05 |
| Association of Radiochemotherapy and Immunotherapy for the Treatment of Unresectable Oesophageal caNcer (NCT03777813) | UNICANCER | 2018-12-05 |
| Effect of Allopurinol or Febuxostat to Prevent Contrast Induced Acute Kidney Injury (CI-AKI) (NCT03767322) | Instituto Nacional de Cardiologia Ignacio Chavez | 2018-12-05 |