| Study of Pimicotinib in Japanese Participants With Tenosynovial Giant Cell Tumor (TGCT) (J-MANEUVER) (NCT07499362) | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany | 2026-03-26 |
| Pirfenidone Capsules in the Treatment of Radiation-induced Lung Injury With or Without Immune Pneumonia (NCT07388680) | Beijing Continent Pharmaceutical Co, Ltd. | 2026-03-26 |
| A Trial to Study if REGN17372 in Combination With Linvoseltamab is Tolerable for Adult Participants With Relapsed/Refractory Multiple Myeloma (NCT07455851) | Regeneron Pharmaceuticals | 2026-03-26 |
| Neutralizing Interleukin (IL)-6 (NCT07493317) | Icahn School of Medicine at Mount Sinai | 2026-03-26 |
| LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis (NCT07415044) | Eli Lilly and Company | 2026-03-26 |
| A Study to Assess the Effects of Zigakibart on IgA Nephropathy. (NCT07146906) | Novartis Pharmaceuticals | 2026-03-26 |
| Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss (NCT07446998) | Veru Inc. | 2026-03-26 |
| Phase 2 Study of Lesigercept in Adult Patients With Chronic Spontaneous Urticaria Who Are Inadequately Controlled by H1-Antihistamines (NCT07415551) | Yuhan Corporation | 2026-03-26 |
| A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Ipilimumab or Cabozantinib in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208) (NCT07293351) | Bristol-Myers Squibb | 2026-03-26 |
| Chemical vs Mechanical Pleural Adhesiolysis for Liberation of Captive Pleura in Stacked Effusion (NCT07713329) | Delta University for Science and Technology | 2026-03-26 |
| Optimize Neoadjuvant Therapy in HER2-Positive Early-Stage Breast Cancer (NCT07402473) | Rutgers, The State University of New Jersey | 2026-03-26 |
| A Study to Evaluate the Efficacy and Safety of E2086 in Adults With Narcolepsy (NCT07493265) | Eisai Inc. | 2026-03-26 |
| JAK Inhibitors for Solid Malignant Tumor Patients With Refractory Immune Checkpoint Inhibitors-related Dermatitis (NCT07530224) | Shixiu Wu | 2026-03-25 |
| GCCC 2578 Randomized Photon vs Proton RT for Newly Diagnosed Gynecologic Primaries (NCT07415681) | University of Maryland, Baltimore | 2026-03-25 |
| Ph 2 Elacestrant in ER Positive Uterine Sarcomas (NCT07467772) | Dana-Farber Cancer Institute | 2026-03-25 |
| Repeated Intravenous Thrombolysis for Ischemic Stroke Within 3.0 Hours of Onset With Tenecteplase (RITIS-TNK) (NCT07375953) | General Hospital of Shenyang Military Region | 2026-03-25 |
| Study Investigating ASP3082 in Patients With Metastatic/Locally Advanced Non-small-cell Lung Cancer (NSCLC) and Pancreatic Ductal Adenocarcinoma (PDAC), With Biomarker Analysis to Characterize Response/Resistance (NCT07483983) | Gustave Roussy, Cancer Campus, Grand Paris | 2026-03-25 |
| Transition to KPL-387 Monotherapy Dosing & Administration Study (NCT07288216) | Kiniksa Pharmaceuticals International, plc | 2026-03-25 |
| Neoadjuvant Therapy With Ensartinib Combined With Chemotherapy for ALK-positive Non - Small Cell Lung Cancer (NSCLC) (NCT07354061) | Tang-Du Hospital | 2026-03-25 |
| Dutasteride in Patients With Low Grade Non-muscle Invasive Bladder Cancer (NCT07420517) | Paul Toren | 2026-03-25 |
| A Prospective, Randomized Study of TACE Combined With Sintilimab, Bevacizumab, and Ipilimumab N01 Treating Advanced HCC (NCT07422753) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-03-25 |
| A Study of SHR-A1904 in Previous Systemic Treatment Failed Biliary Tract Cancer (NCT07450976) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2026-03-25 |
| Developing a First-void Urine-based Infection Model to Study HPV-specific Antibody-virion Interaction Before and After HPV Vaccination (NCT07407569) | Universiteit Antwerpen | 2026-03-25 |
| ONT01 and Gemcitabine/Nab-paclitaxel as Second Line Therapy for Metastatic Pancreatic Ductal Adenocarcinoma (NCT06904378) | Washington University School of Medicine | 2026-03-25 |
| Combined Amivantamab, Carboplatin and Paclitaxel in Unresectable Locally Recurrent or Metastatic Head and Neck Cancer (NCT07062354) | SWOG Cancer Research Network | 2026-03-25 |
| Repeated Intravenous Thrombolysis for Ischemic Stroke With Medium to Large Vessel Occlusion Presenting Within 4.5 Hours of Onset With Tenecteplase (RITIS-TNK2) (NCT07375966) | General Hospital of Shenyang Military Region | 2026-03-25 |
| Acute Nicotine Gum and Tinnitus Loudness in Non-Smoking Adults (NCT07772089) | Xianhui Wang | 2026-03-25 |
| ASK0912 Versus Polymyxin B for Injection in Adults With Hospital-Acquired or Ventilator-Associated Bacterial Pneumonia (NCT07759934) | Jiangsu Aosaikang Pharmaceutical Co., Ltd. | 2026-03-25 |
| Serplulimab Combined With Trastuzumab Rezetecan as Neoadjuvant Therapy for Triple-Negative Breast Cancer (NCT07466303) | Xijing Hospital | 2026-03-25 |
| An Open-Label Study of ML-007C-MA in Adults With Alzheimer's Disease Psychosis (NCT07459660) | MapLight Therapeutics | 2026-03-25 |
| Trastuzumab Rezetecan Neoadjuvant Therapy in THP-Insensitive HER2-Positive Early Breast Cancer (NCT07647263) | The First Affiliated Hospital of Soochow University | 2026-03-24 |
| Efficacy and Safety of Camizestrant Plus Ribociclib in Patients With Breast Cancer (NCT07195227) | MedSIR | 2026-03-24 |
| An Investigational Scan (18F-DOPA PET/CT) for Improving the Clinical Management of Brain Tumors (NCT06667726) | Mayo Clinic | 2026-03-24 |
| Response-Based Dose Reduction of Linvoseltamab in the Treatment of Relapsed, Refractory, or Triple-Class Relapsed/Refractory Multiple Myeloma (NCT07181941) | Fred Hutchinson Cancer Center | 2026-03-24 |
| Zanubritnib and Anti-MAG Neuropathy (NCT07392229) | Azienda Ospedaliera di Padova | 2026-03-24 |
| Subcutaneous Piperacillin/Tazobactam Compared With Intravenous Treatment (NCT07481539) | Azienda Sanitaria Universitaria Friuli Centrale | 2026-03-24 |
| A Study to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants With Moderate to Severe Vernal Keratoconjunctivitis (NCT07169695) | Laboratoires Thea | 2026-03-24 |
| A Cancer Vaccine (STEMVAC) in Combination With Chemotherapy for the Treatment of PD-L1 Negative Metastatic Triple-Negative Breast Cancer (NCT07078604) | University of Washington | 2026-03-24 |
| Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity (NCT06431932) | Ove Andersen | 2026-03-24 |
| Effects of IL-1 Beta Inhibition on Vascular Inflammation in TET2 Clonal Hematopoiesis (NCT06691217) | Massachusetts General Hospital | 2026-03-24 |
| A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002) (NCT07463183) | Merck Sharp & Dohme LLC | 2026-03-24 |
| Pilot Testing a Novel Approach to Pediatric Obesity Treatment (NCT06755827) | Texas Tech University | 2026-03-24 |
| RN1701 Injection in the Treatment of Relapsed/Refractory B-Cell Lymphomas (NCT07506668) | Affiliated Hospital of Nantong University | 2026-03-23 |
| PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease (NCT07355296) | Boehringer Ingelheim | 2026-03-23 |
| Anthocyanin-Rich Table Grape Powder for Prophylaxis of Post-Operative Atrial Fibrillation (NCT05991700) | University of Michigan | 2026-03-23 |
| Coronary Artery Stents in Heart Failure With Preserved Ejection Fraction (NCT07560436) | King's College London | 2026-03-23 |
| A Clinical Study of Adebrelimab in Combination With SHR-8068 and Chemoradiotherapy as Perioperative Therapy for Locally Advanced Rectal Cancer (NCT07454720) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2026-03-23 |
| Chlorhexidine and/or Metronidazole Plus FB301 Pre-treatment Trial (NCT07481955) | Freya Biosciences ApS | 2026-03-23 |
| Genotype-guided Targeted Agents Plus EZH2i for Primary Refractory PTCL (NCT07493330) | Ruijin Hospital | 2026-03-23 |
| MIST (Metabolic Intervention With Semaglutide and THR-β Therapy) Trial (NCT07505303) | Eccogene | 2026-03-23 |
| Phase II Study of Iparomlimab and Tuvonralimab (QL1706) in Combination With Albumin-Bound Paclitaxel and Lenvatinib as Second-Line Therapy for Unresectable or Metastatic Biliary Tract Cancer (NCT07530445) | Sun Yat-sen University | 2026-03-23 |
| Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System (NCT07042295) | National Cancer Institute (NCI) | 2026-03-23 |
| POcus INTERvention for Tailoring Diuretic Strategy in Acute Decompensated Heart Failure (NCT07469722) | Hospital de Clinicas de Porto Alegre | 2026-03-23 |
| Hepatic Arterial Infusion of Sodium Bicarbonate (NaHCO3) Combined With NASOX Regimen and Programmed Death-1 (PD-1) Inhibitors for Pancreatic Cancer Liver Metastases (NCT07504471) | Ruijin Hospital | 2026-03-23 |
| Efficacy and Safety of Sublingual Immunotherapy for Allergic Rhinitis Due to House Dust Mites (NCT07475715) | Zhejiang Wolwo Bio-Pharmaceutical Co., Ltd. | 2026-03-23 |
| KRAS Neoantigen Nanovaccine as Adjuvant Therapy for Colorectal Cancer/Pancreatic Cancer (NCT07353645) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2026-03-23 |
| ZR2 Versus R2 Regimen in the Treatment of Newly Diagnosed Follicular Lymphoma (NCT07505849) | KeshuZhou | 2026-03-23 |
| Cardiac Effects of Mineralocorticoid Receptor Antagonism After Preeclampsia (NCT07238400) | Massachusetts General Hospital | 2026-03-20 |
| Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB Expression (NCT07176182) | Sixth Affiliated Hospital, Sun Yat-sen University | 2026-03-20 |
| Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial (NCT07193927) | AB Biotics, SA | 2026-03-20 |
| A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase Ⅱ Clinical Study to Evaluate the Efficacy and Safety of CMS-D001 in Adult Patients With Moderate to Severe Atopic Dermatitis (NCT07465120) | Dermavon Holdings Limited | 2026-03-20 |
| Pomalidomide Combined With Obinutuzumab in the Treatment of Patients With Relapsed/Refractory Indolent Lymphoma (NCT07441954) | Institute of Hematology & Blood Diseases Hospital, China | 2026-03-20 |
| A Clinical Study of Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes for the Treatment of Premature Ovarian Insufficiency (NCT07510139) | International Peace Maternity and Child Health Hospital | 2026-03-20 |
| Tarlatamab for the Treatment of Extensive Stage Small-cell Lung Cancer (NCT07423585) | Asrar Alahmadi | 2026-03-20 |
| Efficacy and Safety of Rimegepant for Acute Dizziness (NCT07435090) | Shi Tianming | 2026-03-20 |
| Assess Efficacy of a Nanodiamond Periprocedural Skin Care Regimen for Ablative Resurfacing (NCT07462533) | Goldman, Butterwick, Fitzpatrick and Groff | 2026-03-20 |
| Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure (NCT07219459) | CatalYm GmbH | 2026-03-19 |
| A Clinical Study of HRS-8364 in the Treatment of Advanced Solid Tumor Subjects (NCT07446153) | Jiangsu HengRui Medicine Co., Ltd. | 2026-03-19 |
| A Clinical Trial of TQH2929 Injection in Patients With Acute Flare-up of Generalized Pustular Psoriasis (NCT07314060) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2026-03-19 |
| Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis (NCT07474792) | Oruka Therapeutics, Inc. | 2026-03-19 |
| Phase 2/3 Clinical Study of QRX003 Lotion in Subjects With Netherton Syndrome (NCT07538583) | Quoin Pharmaceuticals | 2026-03-19 |
| Clinical Study on TQH2722 Injection Combined With Background Therapy for Seasonal Allergic Rhinitis (NCT07398859) | Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. | 2026-03-19 |
| Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter (NCT07404982) | Beth Israel Deaconess Medical Center | 2026-03-19 |
| The Effect of CBD on Sleep Quality Following Late Evening Exercise (NCT07570472) | KU Leuven | 2026-03-19 |
| A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris (NCT07532603) | Priovant Therapeutics, Inc. | 2026-03-19 |
| The Safety and Efficacy of MRG003 With or Without Putrelimab in Recurrent or Metastatic Salivary Gland Cancer: a Single-center, Open-label Cohort Study (NCT07464366) | Ji Dongmei | 2026-03-19 |
| Study in Advanced Solid Tumor Patients (NCT07300943) | Callio Therapeutics | 2026-03-19 |
| PRO-BOOST-N: Prostate-First Versus Combined Prostate and Nodal Dose Escalation in PSMA PET-Staged Node-Positive Prostate Cancer (NCT07426094) | Affidea Nu-med Center of Oncological DIagnostics and Therapy | 2026-03-19 |
| PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer (NCT07426055) | Affidea Nu-med Center of Oncological DIagnostics and Therapy | 2026-03-19 |
| Comparative Efficacy of hUCMSC-Secretome Delivered Via Microneedling and Intradermal Microinjection as Adjuvant Therapy to NB-UVB in Nonsegmental Vitiligo: A Quasi-Experimental Study (NCT07509242) | Yohanes Firmansyah, dr, MH, MM | 2026-03-18 |
| A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC) (NCT07154290) | Regeneron Pharmaceuticals | 2026-03-18 |
| TACE or Ablation Combined With Sintilimab and Ipilimumab N01 as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With Intermediate-High Recurrence Risk (NCT07487662) | Sun Yat-sen University | 2026-03-18 |
| Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH. (NCT06947473) | Beijing GoBroad Hospital | 2026-03-18 |
| Pharmacogenomics IND SNP Clinical Trial - Alectinib and Single Nucleotide Polymorphisms (NCT05987956) | Han Xu, M.D., Ph.D., FAPCR, Medical Director,, IRB Chair | 2026-03-18 |
| Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma (NCT06498648) | National Cancer Institute (NCI) | 2026-03-18 |
| A Phase II Trial of G01 Eye Drops for Glaucomatous Optic Neuropathy (NCT07777861) | Qingdao WanMing BioCell Pharmaceutics Co.,Ltd. | 2026-03-18 |
| CD19-BCMA Dual Nanobody Based CAR-T Cells for Patients With DSA (NCT07451236) | Chang Yingjun | 2026-03-18 |
| H3K27M-specific Immune Effector Cells Targeting DMG/DIPG (NCT07501156) | Shenzhen Geno-Immune Medical Institute | 2026-03-18 |
| The Impact of Shigellosis and Recommended Treatment in Children (NCT07433426) | Johns Hopkins Bloomberg School of Public Health | 2026-03-18 |
| Efficacy and Safety of TRD205 Tablets for Postoperative Analgesia in Unilateral Total Hip Arthroplasty (Phase IIb) (NCT07543796) | Beijing Tide Pharmaceutical Co., Ltd | 2026-03-18 |
| Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension (NCT07354516) | Qlaris Bio, Inc. | 2026-03-18 |
| Atamparib in Patients With Advanced Solid Tumors (NCT07374419) | Nerviano Medical Sciences (Shanghai) Ltd. | 2026-03-18 |
| A Clinical Trial of Flonoltinib Maleate Tablets in the Treatment of JAK Inhibitor Refractory/Relapsed/Intolerant Patients With Intermediate to High Risk Myelofibrosis (NCT07443306) | Chengdu Zenitar Biomedical Technology Co., Ltd | 2026-03-18 |
| One Trial of JCXH-211 Intratumoral Injection Combined With Anti-PD-1 Antibody in Patients With Malignant Solid Tumors (NCT06781125) | Immorna Biotherapeutics, Inc. | 2026-03-18 |
| Study of AZD4956 as Monotherapy and in Combination With Anti-Cancer Agents in Participants With Advanced/Metastatic Homologous Recombination Deficient Solid Tumours (NCT07446855) | AstraZeneca | 2026-03-17 |
| Group Music Therapy for Chronic Pain Management in Active Duty Service Members: A Randomized Controlled Trial (NCT07755540) | Henry M. Jackson Foundation for the Advancement of Military Medicine | 2026-03-17 |
| A Study of MHB009C in Patients With Advanced Solid Tumors (NCT07326488) | Minghui Pharmaceutical (Hangzhou) Ltd | 2026-03-17 |
| Safety and Efficacy of Baricitinib After Endovascular Treatment in Acute Anterior Circulation Large Vessel Occlusion: A Multicenter, Randomized Controlled Clinical Trial (NCT07449910) | The First Affiliated Hospital of University of Science and Technology of China | 2026-03-17 |
| Efficacy and Safety Study of HS-10542 for IgA Nephropathy (NCT07474636) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2026-03-17 |
| Low Dose Epcoritamab Plus GemOx in R/R DLBCL (NCT07451652) | Hospital Universitario Dr. Jose E. Gonzalez | 2026-03-17 |