| Study of Camrelizumab in Combination With Neoadjuvant Chemotherapy in the Treatment of Osteosarcoma (NCT04294511) | Sun Yat-sen University | 2019-12-26 |
| Cabozantinib and Nivolumab for Carcinoid Tumors (NCT04197310) | Dana-Farber Cancer Institute | 2019-12-26 |
| A Clinical Trial to Assess the Efficacy and Safety of the Combination of a Drug Call Quizartinib With Chemotherapy (FLAG-IDA) in Patients With Acute Myeloid Leukemia That Has Not Responded to the First Treatment or That Has Returned After the First Treatment (NCT04112589) | PETHEMA Foundation | 2019-12-26 |
| Study of Surufatinib Single Agent or Surufatinib Combined With Toripalimab in Patients With Advanced Solid Tumors (NCT04169672) | Hutchison Medipharma Limited | 2019-12-26 |
| Effects of JNJ-53718678 in Adult and Adolescent Participants Who Had a Hematopoietic Stem Cell Transplantation and Who Are Infected With Respiratory Syncytial Virus (RSV) (NCT04056611) | Janssen Sciences Ireland UC | 2019-12-26 |
| Efficacy and Safety of Rifaximin for Patients With Chronic Intestinal Pseudo-obstruction: a Phase 2 Trial (NCT04118699) | Yokohama City University | 2019-12-25 |
| Safety and Efficacy of T8 on Treating Chronic Abnormal Immune Activation in HIV/AIDS Patients (NCT04084444) | Shanghai Pharmaceuticals Holding Co., Ltd | 2019-12-25 |
| Chidamide Combined With Cisplatin for Relapsed or Metastatic Triple-negative Breast Cancer (NCT04192903) | Fudan University | 2019-12-25 |
| Follow-up and Steroid Treatment Results in Intussusception (NCT05640375) | Baskent University | 2019-12-24 |
| Evaluation the Palliative Effects of Colchicine on Primary Hepatic Malignant Tumors Unable to Receive Curative Treatment (NCT04264260) | Kaohsiung Medical University Chung-Ho Memorial Hospital | 2019-12-24 |
| Efficacy and Safety of T-817MA in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD (NCT04191486) | FUJIFILM Toyama Chemical Co., Ltd. | 2019-12-24 |
| Stereotactic Radiosurgery Combination With Anlotinib for Limited Brain Metastases With Perilesional Edema in NSCLC (NCT04147728) | Peking University Third Hospital | 2019-12-24 |
| Safety & Immunogenicity of Enterovirus Type 71 Vaccine in Healthy Adults and Children 6-71months (NCT04467541) | International Centre for Diarrhoeal Disease Research, Bangladesh | 2019-12-24 |
| D-0316 Versus Icotinib in Patients With Locally Advanced or Metastatic EGFR Sensitising Mutation Positive NSCLC (NCT04206072) | Betta Pharmaceuticals Co., Ltd. | 2019-12-24 |
| Autologous Tumor Infiltrating Lymphocytes in Patients With Pretreated Metastatic Triple Negative Breast Cancer (NCT04111510) | Yale University | 2019-12-23 |
| A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies (NCT04172597) | Spectrum Pharmaceuticals, Inc | 2019-12-23 |
| Clinical and Basic Research on the Treatment of Polycystic Ovary Syndrome (NCT04120597) | Jiangxi University of Traditional Chinese Medicine | 2019-12-23 |
| Enasidenib (AG-221) Maintenance Post Allogeneic HCT in Patients With IDH2 Mutation (NCT03728335) | City of Hope Medical Center | 2019-12-23 |
| A Pharmacokinetic and Clotting Activity Study of FVIII-PEGLip (NCT04592692) | Ascension Healthcare Development Limited | 2019-12-23 |
| Study to Evaluate the Efficacy and Safety of Tilpisertib in Adults With Moderately to Severely Active Ulcerative Colitis (NCT04130919) | Gilead Sciences | 2019-12-20 |
| Efficacy and Safety of IgPro10 in Adults With Systemic Sclerosis (SSc) (NCT04138485) | CSL Behring | 2019-12-20 |
| Study of Safety and Tolerability of Nivolumab Treatment Alone or in Combination With Relatlimab or Ipilimumab in Head and Neck Cancer (NCT04080804) | Dan Zandberg | 2019-12-20 |
| A Study of Patidegib Topical Gel, 2%, for the Reduction of Disease Burden of Persistently Developing Basal Cell Carcinomas in Patients With Non-Gorlin High Frequency BCC (NCT04155190) | Sol-Gel Technologies, Ltd. | 2019-12-20 |
| Safety and Efficacy of AK104, a PD-1/CTLA-4 Bispecific Antibody, in Selected Advanced Solid Tumors (NCT04172454) | Akeso | 2019-12-20 |
| Histopathology Following CCH Injection (NCT04236635) | Endo USA Inc., a Keenova Therapeutics Company | 2019-12-20 |
| Use of Oxandrolone to Promote Growth in Infants With HLHS (NCT04090697) | Carelon Research | 2019-12-20 |
| Study for the Treatment of Ocular Chronic Graft-Versus-Host Disease (GVHD) With Amniotic Fluid Eye Drops (AFED) (NCT03298815) | University of Utah | 2019-12-20 |
| Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE) (NCT04239625) | Alkeus Pharmaceuticals, Inc. | 2019-12-20 |
| Optical Tissue Identification for Myocardial Architecture (NCT04017975) | Aditya Kaza | 2019-12-20 |
| Use of Trifluridine/Tipiracil and Oxaliplatin as Induction Chemotherapy for the Treatment of Resectable Esophageal or Gastroesophageal Junction (GEJ) Adenocarcinoma (NCT04097028) | Roswell Park Cancer Institute | 2019-12-20 |
| Pharmacodynamic Equivalence of Ovine Enoxaparin to Lovenox® (NCT04402762) | Indonesia University | 2019-12-20 |
| Efficacy and Safety of P1101 in Polycythemia Vera Patients for Whom the Standard of Treatment is Difficult to Apply (NCT04182100) | PharmaEssentia Japan K.K. | 2019-12-20 |
| PRO-MERIT (Prostate Cancer Messenger RNA Immunotherapy) (NCT04382898) | BioNTech SE | 2019-12-19 |
| GP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Liver Cancer (NCT04206254) | Cure&Sure Biotech Co., LTD | 2019-12-19 |
| 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis. (NCT03993171) | Clene Nanomedicine | 2019-12-19 |
| Standard Versus Double Dose Dolutegravir in Patients With HIV-associated Tuberculosis (NCT03851588) | University of Cape Town | 2019-12-19 |
| A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adults With Moderate to Severe Ulcerative Colitis (NCT04090411) | Hoffmann-La Roche | 2019-12-19 |
| KEYMAKER-U01 Substudy 2: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Treatment-naïve Participants With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Positive Advanced Non-small Cell Lung Cancer (NSCLC) (MK-3475-01B/KEYMAKER-U01B) (NCT04165083) | Merck Sharp & Dohme LLC | 2019-12-19 |
| 31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Parkinson's Disease (NCT03815916) | Clene Nanomedicine | 2019-12-19 |
| Effects of Intravenous GC4419 on the Incidence and Severity of Esophagitis Due to Chemoradiotherapy for Lung Cancer (NCT04225026) | Galera Therapeutics, Inc. | 2019-12-19 |
| Denosumab in Treating Patients With Bone Loss Due to Donor Stem Cell Transplant (NCT03925532) | Roswell Park Cancer Institute | 2019-12-19 |
| TWB-103 for Treating Lower Limb Ulcers on Patients With DM (NCT03624023) | Transwell Biotech Co., Ltd. | 2019-12-19 |
| KEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A) (NCT04165070) | Merck Sharp & Dohme LLC | 2019-12-19 |
| PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study (NCT04129931) | University of North Carolina, Chapel Hill | 2019-12-19 |
| Clinical Trial to Evaluate the Efficacy of Fecal Microbiota Transplantation in Patients With Alopecia Areata (NCT04238091) | Lindsey Bordone | 2019-12-19 |
| Clinical Study of AK101 in Subjects With Moderate to Severe Plaque Psoriasis (NCT04173637) | Akeso | 2019-12-19 |
| Therapeutic Nanocatalysis to Slow Disease Progression of Amyotrophic Lateral Sclerosis (ALS) (NCT04098406) | Clene Nanomedicine | 2019-12-19 |
| Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009) (NCT04191135) | Merck Sharp & Dohme LLC | 2019-12-19 |
| TSR-022 (Anti-TIM-3 Antibody) and TSR-042 (Anti-PD-1 Antibody) in Patients With Liver Cancer (NCT03680508) | University of Hawaii | 2019-12-19 |
| Alpha-1 Blockade for Alcohol Use Disorder (AUD) (NCT04135846) | Brown University | 2019-12-19 |
| Study to Evaluate the Immunogenicity and Safety of a Heterologous Vaccine Regimen Against Ebola (NCT04186000) | Universiteit Antwerpen | 2019-12-18 |
| New Therapies and Biomarkers for Chagas Infection (NCT03981523) | University of Texas, El Paso | 2019-12-18 |
| Tocilizumab in Active Moderate-severe Graves' Orbitopathy (NCT04876534) | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 2019-12-18 |
| A Safety and Efficacy Study of Duvelisib in Relapsed/Refractory Follicular Lymphoma (NCT04707079) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2019-12-18 |
| Delayed Infusion of DCreg in Living Donor Liver Transplantation (NCT04208919) | Angus W. Thomson PhD DSc | 2019-12-18 |
| Durvalumab (MEDI4736) Plus Total Neoadjuvant Therapy (TNT) in Locally Advanced Rectal Cancer (NCT04293419) | Grupo Espanol Multidisciplinario del Cancer Digestivo | 2019-12-18 |
| Perioperative Treatment of Combined SOX With Apatinib and Camrelizumab for Oesophagogastric Cancer (NCT04208347) | Ruijin Hospital | 2019-12-18 |
| A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea) (NCT03740724) | Castle Creek Biosciences, LLC. | 2019-12-18 |
| PSMA-PET Imaging for Detecting Early Metastatic Prostate Cancer in Men w/ High Decipher Test Scores (NCT03495427) | H. Lee Moffitt Cancer Center and Research Institute | 2019-12-18 |
| Decolonization of Gram-negative Multi-resistant Organisms (MDRO) with Donor Microbiota (FMT) (NCT04188743) | University Hospital, Ghent | 2019-12-18 |
| Azacitidine, Venetoclax, and Gilteritinib in Treating Patients With Recurrent/Refractory FLT3-Mutated Acute Myeloid Leukemia, Chronic Myelomonocytic Leukemia, or High-Risk Myelodysplastic Syndrome/Myeloproliferative Neoplasm (NCT04140487) | M.D. Anderson Cancer Center | 2019-12-17 |
| Apalutamide With or Without Stereotactic Body Radiation in Treating Castration-Resistant Prostate Cancer (NCT03503344) | University of California, San Francisco | 2019-12-17 |
| Study to Compare the Effects of Drug Darolutamide and Drug Enzalutamide on Physical Function, Including Balance and Daily Activity, in Patients With Castration-resistant Prostate Cancer (CRPC) (NCT04157088) | Bayer | 2019-12-17 |
| Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery (NCT04220489) | Jacques E. Chelly | 2019-12-17 |
| Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Lower Limb Spasticity (NCT04099667) | Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC | 2019-12-17 |
| Belatacept Pilot Study in Lung Transplantation Immunosuppression in Lung Transplantation (NCT03388008) | Washington University School of Medicine | 2019-12-17 |
| Multiple Doses of DM199 in Patients With Chronic Kidney Disease (REDUX) (NCT04123613) | DiaMedica Therapeutics Inc | 2019-12-17 |
| Comparison of Two Rhythm of Administration of Prostaglandin Gel for Induction of Labor (NCT04413890) | University Hospital Center of Martinique | 2019-12-17 |
| A Clinical Study of Pyrotinib in Patients With HER2-positive Advanced Colorectal Cancer (NCT04380012) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2019-12-17 |
| Evaluation of IPI-549 Combined With Front-line Treatments in Pts. With Triple-Negative Breast Cancer or Renal Cell Carcinoma (NCT03961698) | Infinity Pharmaceuticals, Inc. | 2019-12-17 |
| A Phase Ib/II Study of Fisogatinib(BLU-554) in Subjects With Hepatocellular Carcinoma (NCT04194801) | CStone Pharmaceuticals | 2019-12-16 |
| Circulating Tumor DNA Testing in Predicting Treatment for Patients With Stage IIA Colon Cancer After Surgery (NCT04068103) | NRG Oncology | 2019-12-16 |
| Anakinra as a Rescue Treatment for Allergic Inflammation (NCT04035109) | University of North Carolina, Chapel Hill | 2019-12-16 |
| Phase 1/2a Safety and Efficacy of ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease (NCT04201574) | Allysta Pharmaceutical | 2019-12-16 |
| Clinical Study of Apatinib Combined With Temozolomide in the Treatment of Uncontrolled or Repeated High-grade Gliomas (NCT04253873) | WuHui | 2019-12-16 |
| A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis (NCT04176198) | Sumitomo Pharma America, Inc. | 2019-12-16 |
| Hypofractionated Stereotactic Radiotherapy With Anlotinib in Patients With Recurrent High-Grade Gliomas (NCT04197492) | Huashan Hospital | 2019-12-16 |
| URO-902 in Female Subjects With Overactive Bladder and Urge Urinary Incontinence (NCT04211831) | Urovant Sciences GmbH | 2019-12-16 |
| Study of the Oral Factor D (FD) Inhibitor ALXN2050 in PNH Patients as Monotherapy (NCT04170023) | Alexion Pharmaceuticals, Inc. | 2019-12-16 |
| Ibrutinib and Rituxan for Chronic GVHD (NCT04235036) | Northside Hospital, Inc. | 2019-12-16 |
| Safety, Pharmacodynamics, and Pharmacokinetics of Orally Administered BLD-2660 in Subjects With IPF (NCT04244825) | Blade Therapeutics | 2019-12-15 |
| Copanlisib and Rituximab in Marginal Zone Lymphoma Patients (NCT03474744) | Christian Buske | 2019-12-15 |
| Adrecizumab Dose Escalation Safety and Tolerability Evaluation (ADESTE) (NCT04252937) | GREAT Network Italy | 2019-12-15 |
| Repurposing Chlorpromazine in the Treatment of Glioblastoma (NCT04224441) | Marco G Paggi, MD, PhD | 2019-12-15 |
| Testing Whether Cancers With Specific Mutations Respond Better to Glutaminase Inhibitor, Telaglenastat Hydrochloride, Anti-Cancer Treatment, BeGIN Study (NCT03872427) | National Cancer Institute (NCI) | 2019-12-14 |
| Diabetes AutoimmunitY Withdrawn in Established Patients (DAY) (NCT03794960) | Tolerion, Inc. | 2019-12-14 |
| Diabetes Autoimmunity Withdrawn in New Onset Patients (DAWN) (NCT03794973) | Tolerion, Inc. | 2019-12-14 |
| Efficacy and Safety Evaluation of Sintilimab in Combination With IBI310 as Treatment in Patients With EBV-Positive Gastric Cancer (NCT04202601) | Peking University | 2019-12-13 |
| Copanlisib Hydrochloride and Nivolumab in Treating Patients With Recurrent or Refractory Diffuse Large B-cell Lymphoma or Primary Mediastinal Large B-cell Lymphoma (NCT03484819) | National Cancer Institute (NCI) | 2019-12-13 |
| A Study of CS1001 in Combination With Regorafenib in Patients With Advanced or Refractory Solid Tumors (NCT04200404) | CStone Pharmaceuticals | 2019-12-13 |
| An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris (NCT04148287) | Basilea Pharmaceutica | 2019-12-13 |
| AZD1656 in Transplantation With Diabetes tO PromoTe Immune TOleraNce (NCT05216172) | Queen Mary University of London | 2019-12-13 |
| Vactosertib with Durvalumab in Urothelial Carcinoma Failing Checkpoint Inhibition (NCT04064190) | MedPacto, Inc. | 2019-12-13 |
| Study to Assess Safety,Tolerability,Efficacy of PM01183 and Atezolizumab in Patients w/ Advanced Small Cell Lung Cancer. (NCT04253145) | Fundacion Oncosur | 2019-12-13 |
| A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma (NCT04115631) | ECOG-ACRIN Cancer Research Group | 2019-12-13 |
| Trial of Neoadjuvant and Adjuvant Nivolumab and BMS-813160 With or Without GVAX for Locally Advanced Pancreatic Ductal Adenocarcinomas. (NCT03767582) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2019-12-12 |
| Nitrate Effect on Exercise Capacitance (NCT04297241) | Children's Hospital Medical Center, Cincinnati | 2019-12-12 |
| Efficacy and Safety of Lenvatinib as an Adjuvant Therapy for Hepatocellular Carcinoma (NCT04227808) | Shanghai Zhongshan Hospital | 2019-12-12 |
| A Phase II Study on Adjuvant Vaccination with Dendritic Cells Loaded with Autologous Tumor Homogenate in Resected Stage IV Rare Cancers. (NCT04166006) | Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS | 2019-12-12 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NBI-74788 (Crinecerfont) in Pediatric Participants With Congenital Adrenal Hyperplasia (NCT04045145) | Neurocrine Biosciences | 2019-12-12 |