| Evaluation of Activity and Safety of Two Regimens of Low Dose Oral Selinexor in Participants With Moderate or Severe COVID-19 (NCT04355676) | Karyopharm Therapeutics Inc | 2020-04-30 |
| Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19 (NCT04365985) | Corewell Health East | 2020-04-29 |
| Pharmacokinetic-pharmacodynamic Analysis of Sugammadex for Conventional Reversal in Children (NCT04347486) | Seoul National University Hospital | 2020-04-29 |
| Clinical Study of in Situ Regeneration of Endometrium (NCT04233892) | Yali Hu | 2020-04-29 |
| Study to Describe the Safety, Tolerability, Immunogenicity, and Efficacy of RNA Vaccine Candidates Against COVID-19 in Healthy Individuals (NCT04368728) | BioNTech SE | 2020-04-29 |
| TACE Combined with Anti-PD-1 Antibody in Patients with Advanced Hepatocellular Carcinoma (NCT04297280) | Fudan University | 2020-04-29 |
| Plasma Exchange in Patients With COVID-19 Disease and Invasive Mechanical Ventilation: a Randomized Controlled Trial (NCT04374539) | Fundacion Clinic per a la Recerca Biomédica | 2020-04-29 |
| CPX-351 in Higher Risk Myelodysplastic Syndromes (NCT04273802) | Groupe Francophone des Myelodysplasies | 2020-04-29 |
| Study of Acalabrutinib in Chinese Adult Subjects With Relapsed or Refractory Mantle Cell Lymphoma, Chronic Lymphocytic Leukemia or Other B-cell Malignancies (NCT03932331) | AstraZeneca | 2020-04-29 |
| Study of BGB-10188 as Monotherapy, and in Combination With Zanubrutinib, and Tislelizumab (NCT04282018) | BeiGene | 2020-04-29 |
| COVID-19: Povidone-Iodine Intranasal Prophylaxis in Front-line Healthcare Personnel and Inpatients (NCT04364802) | Nikita Gupta | 2020-04-29 |
| A Study to Evaluate Safety and Efficacy of Convalescent Methylene Blue Treated (MBT) Plasma From Donors Recovered From Coronavirus Disease 2019 (COVID-19) (NCT04547127) | Instituto Grifols, S.A. | 2020-04-29 |
| Treatment With Investigational Convalescent Plasma and Measure Antibody Levels in Patients Hospitalized With COVID-19 (NCT04434131) | University of New Mexico | 2020-04-28 |
| Efficacy of INCMGA00012 in Penile Squamous Cell Carcinoma (ORPHEUS) (NCT04231981) | MedSIR | 2020-04-28 |
| Clinical Trial of Sarilumab in Adults With COVID-19 (NCT04357860) | Maimónides Biomedical Research Institute of Córdoba | 2020-04-28 |
| Anastrozole and Letrozole After Surgery for the Treatment of Stage I-III Breast Cancer (NCT04294225) | Mayo Clinic | 2020-04-28 |
| Phase 2 Trial Using rhDNase to Reduce Mortality in COVID-19 Patients With Respiratory Failure (NCT04445285) | Jon Simmons | 2020-04-28 |
| MultiStem Administration for COVID-19 Induced ARDS (MACoVIA) (NCT04367077) | Healios K.K. | 2020-04-28 |
| Immunotherapy for the Treatment of Advanced Solid Tumor (NCT03658785) | Tongji Hospital | 2020-04-28 |
| Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19 (NCT04381377) | NPO Petrovax | 2020-04-28 |
| Clazakizumab (Anti-Interleukin 6 (IL-6) Monoclonal) Compared to Placebo for Coronavirus Disease 2019 (COVID-19) (NCT04348500) | Cedars-Sinai Medical Center | 2020-04-28 |
| Evaluating the Safety and Efficacy of Autologous Adipose Tissue-derived Mesenchymal Stem Cell Transplantation on Proinflammatory Cytokines and Anti-inflammatory Cytokines on Ageing-related Low-grade Inflammation Patients. (NCT05827757) | DNA International Hospital | 2020-04-28 |
| Clinical Trial to Assess the Safety and Efficacy of Intravenous Administration of Allogeneic Adult Mesenchymal Stem Cells of Expanded Adipose Tissue in Patients With Severe Pneumonia Due to COVID-19 (NCT04366323) | Andalusian Network for Design and Translation of Advanced Therapies | 2020-04-27 |
| Convalescent Plasma Compared to the Best Available Therapy for the Treatment of SARS-CoV-2 Pneumonia (NCT04358783) | Hospital Universitario Dr. Jose E. Gonzalez | 2020-04-27 |
| Pilot Study of Antithrombin as Prophylaxis of Acute Respiratory Distress Syndrome in Patients With COVID-19 (NCT04745442) | Maimónides Biomedical Research Institute of Córdoba | 2020-04-27 |
| A Single-blinded, Randomized, Placebo Controlled Phase II Trial of Prophylactic Treatment With Oral Azithromycin Versus Placebo in Cancer Patients Undergoing Antineoplastic Treatment During the Corona Virus Disease 19 (COVID-19) Pandemic (NCT04369365) | Prof. Dr. Matthias Preusser | 2020-04-27 |
| Avdoralimab an Anti-C5aR Antibody, in Patients With COVID-19 Severe Pneumonia ( FORCE ) (NCT04371367) | Assistance Publique Hopitaux De Marseille | 2020-04-27 |
| Erdafitinib and Abiraterone Acetate or Enzalutamide in Treating Patients With Double Negative Prostate Cancer (NCT03999515) | University of Washington | 2020-04-27 |
| COlchicine in Moderate-severe Hospitalized Patients Before ARDS to Treat COVID-19 (NCT04363437) | Maimonides Medical Center | 2020-04-26 |
| A Phase I/II Study of XELOXIRI and Bevacizumab as First-line Treatment in Metastatic Colorectal Cancer (NCT04380103) | Chinese Academy of Medical Sciences | 2020-04-26 |
| Tocilizumab in the Treatment of Coronavirus Induced Disease (COVID-19) (NCT04335071) | Insel Gruppe AG, University Hospital Bern | 2020-04-26 |
| A Study of a PD-1/CTLA-4 Bispecific Antibody AK104 in Patients With Metastatic Nasopharyngeal Carcinoma (NCT04220307) | Akeso | 2020-04-26 |
| Phase I/II Study of SY-3505 in Patients With ALK-positive Advanced Non-small Cell Lung Cancer (NCT05257512) | Shouyao Holdings (Beijing) Co. LTD | 2020-04-26 |
| Safety and Efficacy Trial of Zavegepant* Intranasal for Hospitalized Patients With COVID-19 Requiring Supplemental Oxygen (NCT04346615) | Pfizer | 2020-04-25 |
| Use of UC-MSCs for COVID-19 Patients (NCT04355728) | Camillo Ricordi | 2020-04-25 |
| Combined PD1 Inhibitor and Decitabine in Elderly Patients With Relapse and Refractory Acute Myeloid Leukemia (NCT04353479) | Shanghai Jiao Tong University School of Medicine | 2020-04-25 |
| Single-Blind Study of a Single Dose of Peginterferon Lambda-1a Compared With Placebo in Outpatients With Mild COVID-19 (NCT04331899) | Stanford University | 2020-04-25 |
| Phase 2 Trial of Voyager V1 in Combination With Cemiplimab in Cancer Patients (NCT04291105) | Vyriad, Inc. | 2020-04-24 |
| A Study of AK104 in Subjects With Locally Advanced Unresectable or Metastatic MSI-H/dMMR Solid Tumors (NCT04547101) | Akeso | 2020-04-24 |
| Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer (NCT03992456) | Academic and Community Cancer Research United | 2020-04-24 |
| Canakinumab in Covid-19 Cardiac Injury (The Three C Study) (NCT04365153) | The Cleveland Clinic | 2020-04-24 |
| A Phase Ⅱ Study of Hemay808 for Atopic Dermatitis Patients (NCT04352595) | Tianjin Hemay Pharmaceutical Co., Ltd | 2020-04-24 |
| A Study to Evaluate the Efficacy and Safety of Sirukumab in Confirmed Severe or Critical Confirmed Coronavirus Disease (COVID)-19 (NCT04380961) | Janssen Pharmaceutica N.V., Belgium | 2020-04-24 |
| Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas (NCT04305444) | Zhejiang DTRM Biopharma | 2020-04-24 |
| Senicapoc in COVID-19 Patients With Severe Respiratory Insufficiency (NCT04594668) | University of Aarhus | 2020-04-24 |
| INNATE: Immunotherapy During Neoadjuvant Therapy for Rectal Cancer (NCT04130854) | University of Texas Southwestern Medical Center | 2020-04-24 |
| Radiation Eliminates Storming Cytokines and Unchecked Edema as a 1-Day Treatment for COVID-19 (NCT04366791) | Emory University | 2020-04-24 |
| Toripalimab Plus Rituximab Followed by R-CHOP for Elderly Patients With Untreated Diffused B Cell Lymphoma (NCT04058470) | Huiqiang Huang | 2020-04-24 |
| Sirolimus Treatment in Hospitalized Patients With COVID-19 Pneumonia (NCT04341675) | University of Cincinnati | 2020-04-24 |
| An Adaptive Study of Favipiravir Compared to Standard of Care in Hospitalized Patients With COVID-19 (NCT04434248) | Chromis LLC | 2020-04-23 |
| Anlotinib Combined With TACE in Hepatocellular Carcinoma Patients at High Risk of Post Surgery Recurrence (NCT04213118) | First Affiliated Hospital Xi'an Jiaotong University | 2020-04-23 |
| ATG-008 Combined With Toripalimab in Advanced Solid Tumors (NCT04337463) | Sichuan University | 2020-04-23 |
| Clinical Trial to Evaluate the Efficacy of Treatment With Hyperimmune Plasma Obtained From Convalescent Antibodies of COVID-19 Infection (NCT04366245) | Andalusian Network for Design and Translation of Advanced Therapies | 2020-04-23 |
| Treatment of Pulmonary Fibrosis Due to COVID-19 With Fuzheng Huayu (NCT04279197) | ShuGuang Hospital | 2020-04-23 |
| A Trial Investigating the Safety and Effects of Four BNT162 Vaccines Against COVID-19 in Healthy and Immunocompromised Adults (NCT04380701) | BioNTech SE | 2020-04-23 |
| A Study of a Candidate COVID-19 Vaccine (COV001) (NCT04324606) | University of Oxford | 2020-04-23 |
| A Study of DCC-2618 (Ripretinib) In Patients With With Advanced Gastrointestinal Stromal Tumors (GIST) (NCT04282980) | Zai Lab (Shanghai) Co., Ltd. | 2020-04-23 |
| Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-CSI in Subjects With Dry Eye Disease. (NCT04362670) | Ocular Therapeutix, Inc. | 2020-04-23 |
| Study of the Efficacy and Safety of a Single Administration of Olokizumab and RPH-104 With Standard Therapy in Patients With Severe Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection (COVID-19) (NCT04380519) | R-Pharm International, LLC | 2020-04-23 |
| VR-CAP in the First-line Treatment for Patients With Marginal Zone Lymphoma (NCT04433156) | Henan Cancer Hospital | 2020-04-22 |
| Precision Medicine for Patients With Identified Actionable Mutations (NCT04111107) | Wake Forest University Health Sciences | 2020-04-22 |
| Nebulised Rt-PA for ARDS Due to COVID-19 (NCT04356833) | University College, London | 2020-04-22 |
| A Study of Camrelizumab As Consolidation Therapy After Radical Concurrent Chemoradiotherapy In Locally Advanced ESCC (NCT04286958) | Hebei Medical University Fourth Hospital | 2020-04-22 |
| A Multi-Center Phase 2 Study to Evaluate Efficacy and Safety of Oral Abexinostat as Monotherapy in Patients With Relapsed or Refractory Follicular Lymphoma (NCT03934567) | Xynomic Pharmaceuticals, Inc. | 2020-04-22 |
| Hydroxychloroquine for the Treatment of Mild COVID-19 Disease (NCT04340544) | University Hospital Tuebingen | 2020-04-22 |
| Sarilumab Treatment In cytoKinE Storm Caused by Infection With COVID-19 (NCT04661527) | Clinica Universidad de Navarra, Universidad de Navarra | 2020-04-22 |
| Combination of Anti-PD-1 Antibody and Chemotherapy for Unresectable Intrahepatic Cholangiocarcinoma (NCT04413734) | Zhejiang University | 2020-04-22 |
| A Study to Investigate Efficacy and Safety With Oral AZD9833 Compared With Intramuscular Fulvestrant in Post-menopausal Women at Least 18 Years of Age With Advanced ER-positive HER2 Negative Breast Cancer (NCT04214288) | AstraZeneca | 2020-04-22 |
| Ruxolitinib in Covid-19 Patients With Defined Hyperinflammation (NCT04338958) | University of Jena | 2020-04-22 |
| A Study of T3011 Administered Via Intratumoral Injection in Patients With Advanced Solid Tumors (NCT05602792) | ImmVira Pharma Co. Ltd | 2020-04-21 |
| In Men With Metastatic Prostate Cancer, What is the Safety and Benefit of Lutetium-177 PSMA Radionuclide Treatment in Addition to Chemotherapy (NCT04343885) | Peter MacCallum Cancer Centre, Australia | 2020-04-21 |
| Plasma Therapy of COVID-19 in Severely Ill Patients (NCT04359810) | Max O'Donnell | 2020-04-21 |
| Saved From COVID-19 - Chloroquine (CQ) Prophylaxis for Health Care Workers at Risk for COVID (NCT04349371) | Columbia University | 2020-04-21 |
| Corticosteroids During Covid-19 Viral Pneumonia Related to SARS-Cov-2 Infection (NCT04344288) | Hospices Civils de Lyon | 2020-04-21 |
| Test and Treat COVID 65plus+ (NCT04351516) | University Hospital Tuebingen | 2020-04-21 |
| ImmunoBreast - A Phase Ib Study (NCT04609215) | Henrik Ditzel | 2020-04-21 |
| A Clinical Trial to Determine the Safety and Efficacy of HB-adMSCs to Provide Protection Against COVID-19 (NCT04349631) | Hope Biosciences Research Foundation | 2020-04-20 |
| Trial Evaluating Efficacy and Safety of Anticoagulation in Patients With COVID-19 Infection, Nested in the Corimmuno-19 Cohort (NCT04344756) | Assistance Publique - Hôpitaux de Paris | 2020-04-20 |
| Osteoarthritis of the Knee Pain Study Using a CBD and THC Sublingual Tablet (NCT04195269) | Pure Green | 2020-04-20 |
| Efficacy of Convalescent Plasma Therapy in Severely Sick COVID-19 Patients (NCT04346446) | Institute of Liver and Biliary Sciences, India | 2020-04-20 |
| Efficacy of Faviprevir in COVID-19 Treatment (NCT04351295) | Tanta University | 2020-04-20 |
| Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas (NCT03532295) | Washington University School of Medicine | 2020-04-20 |
| Estrogen Patch for COVID-19 Symptoms (NCT04359329) | Sharon Nachman | 2020-04-20 |
| Histopathologic Effect of Calcium Electroporation on Cancer in the Skin (NCT04259658) | Zealand University Hospital | 2020-04-20 |
| MGD013 Monotherapy and Combination With Brivanib Dose Escalation and Expansion Study in Advanced Liver Cancer Patients (NCT04212221) | Zai Lab (Shanghai) Co., Ltd. | 2020-04-20 |
| Colchicine Counteracting Inflammation in COVID-19 Pneumonia (NCT04322565) | Azienda Ospedaliero-Universitaria di Parma | 2020-04-20 |
| Atovaquone and Azithromycin Combination for Confirmed COVID-19 Infection (NCT04339426) | HonorHealth Research Institute | 2020-04-20 |
| ASC Therapy for Patients With Severe Respiratory COVID-19 (NCT04341610) | Rigshospitalet, Denmark | 2020-04-20 |
| Hyperbaric Oxygen Therapy After Stroke - PILOT (NCT04149379) | Norwegian Underwater Intervention (NUI) | 2020-04-20 |
| Efficacy of Melatonin in the Prophylaxis of Coronavirus Disease 2019 (COVID-19) Among Healthcare Workers. (NCT04353128) | Instituto de Investigación Hospital Universitario La Paz | 2020-04-20 |
| A Study of LY3127804 in Participants With COVID-19 (NCT04342897) | Eli Lilly and Company | 2020-04-20 |
| Safety and Efficacy of ARQ-252 Cream in Subjects With Chronic Hand Eczema (NCT04378569) | Arcutis Biotherapeutics, Inc. | 2020-04-20 |
| Preventing COVID-19 in Healthcare Workers With HCQ: A RCT (NCT04347889) | Stony Brook University | 2020-04-20 |
| Nitazoxanide Therapy for Patients With COVID-19 Pneumonia (NCT04561219) | Universidade Federal do Rio de Janeiro | 2020-04-19 |
| Potential Efficacy of Convalescent Plasma to Treat Severe COVID-19 and Patients at High Risk of Developing Severe COVID-19 (NCT04347681) | King Fahad Specialist Hospital Dammam | 2020-04-18 |
| Colchicine in COVID-19: a Pilot Study (NCT04375202) | University Of Perugia | 2020-04-18 |
| A Safety and Efficacy Study of Lucinactant for Inhalation in Preterm Neonates 26 to 32 Weeks Gestational Age (NCT04264156) | Windtree Therapeutics | 2020-04-18 |
| Nitric Oxide Inhalation Therapy for COVID-19 Infections in the ED (NCT04338828) | Massachusetts General Hospital | 2020-04-18 |
| Methylprednisolone in the Treatment of Patients With Signs of Severe Acute Respiratory Syndrome in Covid-19 (NCT04343729) | Fundação de Medicina Tropical Dr. Heitor Vieira Dourado | 2020-04-18 |
| Darolutamide in Patients With Androgen Receptor-Positive Salivary Gland Carcinoma (DISCOVARY) (NCT05694819) | National Cancer Center Hospital East | 2020-04-17 |