| GnRH Therapy on Cognition in Down Syndrome (NCT04390646) | Nelly Pitteloud | 2020-08-27 |
| The Relapse from MRD Negativity As Indication for Treatment (REMNANT) Study (NCT04513639) | Oslo University Hospital | 2020-08-27 |
| PK Profile and Preliminary Efficacy of TNP-2092 Capsules in Liver Cirrhosis Patients With Hyperammonemia (NCT06135675) | TenNor Therapeutics (Suzhou) Limited | 2020-08-27 |
| Catalysing the Containment of COVID-19 (NCT04523090) | University of Cape Town | 2020-08-27 |
| IDH2-Post-Allo-Trial for Patients with IDH2-mut Myeloid Neoplasms After Allo-SCT (NCT04522895) | Heinrich-Heine University, Duesseldorf | 2020-08-27 |
| VIR-7831 for the Early Treatment of COVID-19 in Outpatients (NCT04545060) | Vir Biotechnology, Inc. | 2020-08-27 |
| A Study to Assess Safety, Tolerability, and Immunogenicity of V591 (COVID-19 Vaccine) in Healthy Participants (V591-001) (NCT04498247) | Merck Sharp & Dohme LLC | 2020-08-27 |
| KUR-113 Bone Graft Versus Local Autograft for the Treatment of Single-level Transforaminal Lumbar Interbody Fusion (NCT04294004) | Kuros Biosurgery AG | 2020-08-27 |
| R33: Levetiracetam in Early Psychosis (NCT04317807) | NYU Langone Health | 2020-08-27 |
| IBI310 in Combination with Sintilimab in Patients with DNA Mismatch Repair Deficient (dMMR)/microsatellite Instability High (MSI-H) Locally-advanced or Metastatic Colorectal Cancer (NCT04258111) | Innovent Biologics (Suzhou) Co. Ltd. | 2020-08-27 |
| Coronavirus Disease 2019 (COVID-19) Antibody Plasma Research Study in Hospitalized Patients (NCT04524507) | University of North Carolina, Chapel Hill | 2020-08-27 |
| Oral Supplementation of 2'-Fucosyllactose in Allogeneic Bone Marrow Transplant Recipients (NCT04263597) | Children's Hospital Medical Center, Cincinnati | 2020-08-26 |
| A Clinical Study in Patients With High-risk Recurrent Primary Hepatocellular Carcinoma Using Autologous TILs (NCT04538313) | CAR-T (Shanghai) Cell Biotechnology Co., Ltd. | 2020-08-26 |
| DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab (NCT03688178) | Annick Desjardins, MD | 2020-08-26 |
| A Ph2b to Evaluate Clinical Efficacy and Safety of Tildacerfont in Adult CAH (NCT04457336) | Spruce Biosciences | 2020-08-26 |
| Efficacy and Safety of BIO101 in the Prevention of Respiratory Deterioration in Hospitalized COVID-19 Patients (NCT04472728) | Biophytis | 2020-08-26 |
| Clinical Study of Camrelizumab Combined With APatinib and Albumin Paclitacxel in Patients With Advanced Lung Adenocarcinoma (NCT04459078) | Hunan Cancer Hospital | 2020-08-26 |
| A Phase II Study of HY209 Gel for Atopic Dermatitis Patients (Shaperon) (NCT04530643) | Shaperon | 2020-08-26 |
| Clinical Study on the Efficacy and Safety of BAT5906 Injection (NCT05141994) | Bio-Thera Solutions | 2020-08-26 |
| Study of the Efficacy and Safety of AMT-101 in Subjects With Ulcerative Colitis (LOMBARD) (NCT04583358) | Applied Molecular Transport | 2020-08-26 |
| A Trial of LONSURF in Recurrent/Metastatic Nasopharyngeal Carcinoma (NCT04627961) | National University Hospital, Singapore | 2020-08-26 |
| Dose-Deescalated 3-Fraction Stereotactic Body Radiotherapy For Centrally Located Lung Cancer (NCT04210492) | Yale University | 2020-08-26 |
| Zanubrutinib, Lenalidomide and Rituximab (ZR2) in Elderly Treatment-naive Patients With Diffuse Large B-cell Lymphoma (DLBCL) (NCT04460248) | Ruijin Hospital | 2020-08-26 |
| Safety and Efficacy of EDP1815 in the Treatment of Patients Hospitalized With COVID-19 Infection (NCT04488575) | Evelo Biosciences, Inc. | 2020-08-26 |
| Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread (NCT04233866) | ECOG-ACRIN Cancer Research Group | 2020-08-26 |
| A Study of LY3041658 in Adults With Hidradenitis Suppurativa (NCT04493502) | Eli Lilly and Company | 2020-08-26 |
| To Assess the Efficacy and Safety of INCB054707 in Participants With Hidradenitis Suppurativa (NCT04476043) | Incyte Corporation | 2020-08-25 |
| Charité Trial of Cenicriviroc (CVC) Treatment for COVID-19 Patients (NCT04500418) | Charite University, Berlin, Germany | 2020-08-25 |
| RGX-314 Gene Therapy Administered in the Suprachoroidal Space for Participants With Neovascular Age-Related Macular Degeneration (nAMD) (NCT04514653) | AbbVie | 2020-08-25 |
| A Phase II, Open-Label, Study of Subcutaneous Canakinumab, an Anti-IL-1β Human Monoclonal Antibody, for Patients With Low or Int-1 Risk IPSS/IPSS-R Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia (NCT04239157) | M.D. Anderson Cancer Center | 2020-08-25 |
| Exome Analysis (Complexe vs Simple) to Help the Therapeutic Decision for the Precision Medicine (NCT04614480) | Centre Georges Francois Leclerc | 2020-08-25 |
| Safety and Efficacy of Convalescent Plasma Transfusion for Patients With COVID-19 (NCT04388410) | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | 2020-08-25 |
| First-line Nab-paclitaxel Plus Cisplatin Plus Camrelizumab in mTNBC Patients (NCT04537286) | Fudan University | 2020-08-25 |
| Efficacy of Repeated Locoregional Anesthetics Blocks With Bupivacaine in Patients Suffering of Chronic Dentoalveolar Pain. (NCT04207411) | University Hospital, Clermont-Ferrand | 2020-08-25 |
| Chronic Pain Master Protocol (CPMP): A Study of LY3016859 in Participants With Chronic Low Back Pain (NCT04529096) | Eli Lilly and Company | 2020-08-25 |
| Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia (NCT04505254) | M.D. Anderson Cancer Center | 2020-08-25 |
| Safety and Efficacy of CD19 and CD22 Targeted CAR-T Therapy for Relapsed/Refractory B Cell Leukemia and Lymphoma (NCT04648475) | Chongqing Precision Biotech Co., Ltd | 2020-08-25 |
| Efficacy and Safety of SYNB1618 and SYNB1934 in Adult Patients With Phenylketonuria (NCT04534842) | Synlogic | 2020-08-25 |
| Bioequivalence Study to Compare Diclofenac Potassium Coated Tablet Versus Cataflam® 50 Coated Tablet (NCT05082662) | Humanis Saglık Anonim Sirketi | 2020-08-25 |
| Probiotic (LGG) for Veterans With PTSD (NCT04150380) | VA Eastern Colorado Health Care System | 2020-08-24 |
| PRV-015 in Gluten-free Diet Non-responsive Celiac Disease (NCT04424927) | Provention Bio, a Sanofi Company | 2020-08-24 |
| A Study of RC48-ADC in Subjects With HER2 Overexpressed Metastatic Biliary Tract Cancer (NCT04329429) | RemeGen Co., Ltd. | 2020-08-24 |
| Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel (NCT04449549) | National Cancer Institute (NCI) | 2020-08-24 |
| Safety, Tolerability and Renal Effects of APX-115 in Subjects With Type 2 Diabetes and Nephropathy (NCT04534439) | Aptabio Therapeutics, Inc. | 2020-08-24 |
| Pre-Incisional Ketorolac for Patients Undergoing Surgery for Non-Small Cell Lung Cancer and Renal Cell Carcinoma (NCT04495894) | Emory University | 2020-08-24 |
| Randomized Open Label Phase II Study to Evaluate the Efficacy of Enzalutamide in High Risk Male Outpatients With COVID-1 (NCT04456049) | Ricardo Pereira Mestre | 2020-08-24 |
| Impact of Project ECHO on Improving the Quality of Palliative Care in Patients With Advanced Cancer and Their Caregivers in Underserved Areas of Kenya, Nigeria, Ghana, South Africa, India, and Ethiopia (NCT04984551) | M.D. Anderson Cancer Center | 2020-08-24 |
| 18F-Fluciclovine PET and Multiparametric MR Imaging (NCT03925675) | Loma Linda University | 2020-08-24 |
| ProTarget - A Danish Nationwide Clinical Trial on Targeted Cancer Treatment Based on Genomic Profiling (NCT04341181) | Ulrik Lassen | 2020-08-24 |
| Study of AZD1222 for the Prevention of COVID-19 in Japan (NCT04568031) | AstraZeneca | 2020-08-23 |
| Vadadustat for the Prevention and Treatment of Acute Respiratory Distress Syndrome (ARDS) in Hospitalized Patients With Coronavirus Disease 2019 (COVID-19) (NCT04478071) | The University of Texas Health Science Center, Houston | 2020-08-22 |
| Rivaroxaban Plus ASA in Embolic Stroke of Undetermined Source(AREST-ESUS) (NCT04273516) | Mazandaran University of Medical Sciences | 2020-08-22 |
| Comparing the Efficacy of Topical Tazarotene Gel 0.1% v/s Microneedling in Atrophic Post Acne Scars (NCT05573425) | Jinnah Postgraduate Medical Centre | 2020-08-22 |
| Open Label Two-Arm Study to Evaluate Rilzabrutinib in IgG4-Related Disease Participants (NCT04520451) | Principia Biopharma, a Sanofi Company | 2020-08-22 |
| Polatuzumab Vedotin and Combination Chemotherapy for the Treatment of Previously Untreated Lymphoma (NCT04479267) | Barbara Ann Karmanos Cancer Institute | 2020-08-21 |
| Success of Long-acting Anti-inflammatories After Anterior Cruciate Ligament and Meniscal Injury (NCT04331002) | Austin V Stone | 2020-08-21 |
| Study to Assess Intracerebroventricular (ICV) Delivery of CT-010 in Subjects With Focal Seizures, With Temporal Lobe Onset With or Without Secondary Generalization (NCT04153175) | Cerebral Therapeutics LLC | 2020-08-21 |
| Speech Entrainment for Aphasia Recovery (NCT04364854) | Medical University of South Carolina | 2020-08-21 |
| A Clinical Trial Utilizing Dantrolene in Patients With Ventricular Arrhythmias. (NCT04134845) | Vanderbilt University Medical Center | 2020-08-21 |
| A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants (NCT04335539) | Shionogi | 2020-08-21 |
| NFX-179 Topical Gel Treatment in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF) (NCT04435665) | NFlection Therapeutics, Inc. | 2020-08-21 |
| Clinical Trial of Green Tea Catechins in Men on Active Surveillance (NCT04300855) | H. Lee Moffitt Cancer Center and Research Institute | 2020-08-21 |
| Opaganib, a Sphingosine Kinase-2 (SK2) Inhibitor in COVID-19 Pneumonia (NCT04467840) | RedHill Biopharma Limited | 2020-08-21 |
| Tislelizumab in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (NCT04318080) | BeiGene | 2020-08-20 |
| A Study Of Naxitamab , Granulocyte Macrophage Colony Stimulating Factor For Patients With Relapsed /Refractory , Soft Tissue or Anti GD2 Immunotherapy Refractory Neuroblastoma (NCT06438614) | Fundació Sant Joan de Déu | 2020-08-20 |
| PRECISE CURATE.AI Pilot Clinical Trial (NCT04522284) | National University Hospital, Singapore | 2020-08-20 |
| Vaginal Microbiome Transplantation for Recurrent Bacterial Vaginosis (NCT04517487) | Hadassah Medical Organization | 2020-08-20 |
| Composite Steep-pulseTreatment Device Used in Patients With Benign Prostatic Hyperplasia (NCT05531344) | REMD Medical Technology | 2020-08-20 |
| Study of APG-1252 Plus Paclitaxel in Patients With Relapsed/Refractory Small Cell Lung Cancer (NCT04210037) | Ascentage Pharma Group Inc. | 2020-08-20 |
| A Study to Evaluate the Safety and Effectiveness of a Nasal Spray to Treat Perennial Allergic Rhinitis (NCT06051786) | Synmosa Biopharma Corp. | 2020-08-20 |
| Inflammation Reduction by TREhalose AdminisTration (NCT03700424) | Mashhad University of Medical Sciences | 2020-08-20 |
| YY-20394 、GEMOX Treatment Diffuse Large B-cell Lymphoma Single Arm, Open, Multicentrized Phase 1b/2 Clinical Trial (NCT04500561) | Shanghai YingLi Pharmaceutical Co. Ltd. | 2020-08-20 |
| Actuate 1901: 9-ING-41 in Myelofibrosis (NCT04218071) | Actuate Therapeutics Inc. | 2020-08-20 |
| the Investigation Into Beneficial Effects of High-dose Interferon Beta 1-a, Compared to Low-dose Interferon Beta 1-a in Moderate to Severe Covid-19 (NCT04521400) | Shahid Beheshti University of Medical Sciences | 2020-08-20 |
| Trial of the Safety and Efficacy of Epcoritamab in Japanese Subjects With Relapsed or Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (R/R B-NHL) (NCT04542824) | Genmab | 2020-08-20 |
| MRI-Guided Radiation Therapy for the Treatment of Early-Stage Kidney Cancer, the MRI-MARK Trial (NCT04580836) | M.D. Anderson Cancer Center | 2020-08-19 |
| Safety and Anti-coronavirus Response of Suppression of Host Nucleotide Synthesis in Patients With COVID-19 (NCT04425252) | Clear Creek Bio, Inc. | 2020-08-19 |
| A Study of Dabrafenib in Combination With Trametinib in Chinese Patients With BRAF V600E Mutant Metastatic NSCLC (NCT04452877) | Novartis Pharmaceuticals | 2020-08-19 |
| A Study Evaluating the Efficacy and Safety of HSK21542 Injection for Analgesia in Subjects Undergoing Colonoscopy (NCT04470128) | Haisco Pharmaceutical Group Co., Ltd. | 2020-08-19 |
| Efficacy of Intravenous Anakinra and Ruxolitinib During COVID-19 Inflammation (NCT04366232) | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | 2020-08-19 |
| Sequential Testosterone and Enzalutamide Prevents Unfavorable Progression (NCT04363164) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2020-08-19 |
| A Study of NM21-1480 in Adult Patients With Advanced Solid Tumors (NCT04442126) | Numab Therapeutics AG | 2020-08-19 |
| A Study of Apalutamide (Adjuvant Treatment) and Androgen Deprivation Therapy (ADT) in Participants Who Have Undergone Radical Prostatectomy (RP) for Non-metastatic Prostate Cancer and Who Are at High Risk for Metastases (NCT04523207) | Janssen Research & Development, LLC | 2020-08-19 |
| A Phase 1/ Phase 2 Study of TTHX1114(NM141) (NCT04520321) | Trefoil Therapeutics, Inc. | 2020-08-19 |
| A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS) (NCT04419649) | Takeda | 2020-08-19 |
| Intramuscular Effect of Polymerized Type I Collagen on the Cytokine Storm in COVID-19 Patients (NCT04517162) | Janette Furuzawa Carballeda | 2020-08-19 |
| Ivermectin to Prevent Hospitalizations in COVID-19 (NCT04529525) | Instituto de Cardiología de Corrientes | 2020-08-19 |
| Evaluate the Safety and Tolerability, for Nirsevimab in Immunocompromised Children (NCT04484935) | AstraZeneca | 2020-08-19 |
| Sildenafil in COVID-19 (NCT04489446) | Universidad Nacional Andres Bello | 2020-08-19 |
| ACTIV-2: A Study for Outpatients With COVID-19 (NCT04518410) | National Institute of Allergy and Infectious Diseases (NIAID) | 2020-08-19 |
| A Study of LY3471851 in Adults With Systemic Lupus Erythematosus (SLE) (NCT04433585) | Nektar Therapeutics | 2020-08-19 |
| Donor Stem Cell Transplant After Chemotherapy for the Treatment of Recurrent or Refractory High-Risk Solid Tumors in Pediatric and Adolescent-Young Adults (NCT04530487) | M.D. Anderson Cancer Center | 2020-08-19 |
| Low-Dose Ketamine in Children With ADNP Syndrome (NCT04388774) | Alexander Kolevzon | 2020-08-19 |
| Study of Capmatinib and Spartalizumab/Placebo in Advanced NSCLC Patients With MET Exon 14 Skipping Mutations (NCT04323436) | Novartis Pharmaceuticals | 2020-08-19 |
| Fractionated and Multiple Dose 225Ac-J591 for Progressive mCRPC (NCT04506567) | Weill Medical College of Cornell University | 2020-08-18 |
| A Study of Evaluating the Safety and Efficacy of ATG-010 Combined With Chemotherapy Sequential With ATG-010 Monotherapy Maintenance in Peripheral T- and NK/T-cell Lymphoma (NCT04425070) | Antengene Corporation | 2020-08-18 |
| A Study With Pembrolizumab in Combination With Dual Anti-HER2 Blockade With Trastuzumab and Pertuzumab in Early Breast Cancer Patients With Molecular HER2-enriched Intrinsic Subtype (Keyriched-1) (NCT03988036) | Women's Cancer Study Group GmbH | 2020-08-18 |
| Copanlisib With Rituximab-Bendamustine in Patients With Relapsed-Refractory Diffuse Large B-cell Lymphoma (NCT04433182) | Fondazione Italiana Linfomi - ETS | 2020-08-18 |
| Viral Specific T-cells for Treatment of Viral Infections After Solid Organ Transplant (NCT04331275) | Children's Hospital Medical Center, Cincinnati | 2020-08-18 |
| Study of VIR-2218 in Patients With Chronic Hepatitis B in Mainland China (NCT04507269) | Brii Biosciences Limited | 2020-08-18 |