| Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS) (NCT04502433) | Chiesi Farmaceutici S.p.A. | 2021-01-06 |
| IRAK 4 Inhibitor (PF-06650833) in Hospitalized Patients With COVID-19 Pneumonia and Exuberant Inflammation. (NCT04933799) | Giovanni Franchin, M.D, Ph.D | 2021-01-06 |
| Piclidenoson for Treatment of COVID-19 (NCT04333472) | Can-Fite BioPharma | 2021-01-06 |
| Osimertinib Then Chemotherapy in EGFR-mutated Lung Cancer with Osimertinib Third-line Rechallenge (NCT04335292) | Mark Vincent | 2021-01-06 |
| A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases (NCT04511013) | SWOG Cancer Research Network | 2021-01-06 |
| Efficacy and Safety of G001 in Patients With Osteoarthritis (OA) of the Knee (NCT05007808) | BUZZZ Pharmaceuticals Limited | 2021-01-06 |
| Fibromyalgia and Naltrexone: The FINAL Study (NCT04270877) | Odense University Hospital | 2021-01-06 |
| The Effects of Microbiological Spectrum Changes to Improve Cognitive Health in Aging Population (NCT05051501) | National Institute of Mental Health, Czech Republic | 2021-01-06 |
| Study of the Safety and Efficacy of STI-5656 (Abivertinib Maleate) in Subjects Hospitalized Due to COVID-19 (NCT04528667) | Sorrento Therapeutics, Inc. | 2021-01-06 |
| Polaprezinc Treatment for Enzalutamide- or Abiraterone-resistant CRPC (NCT05549778) | Jiangnan University | 2021-01-06 |
| Patient-centered Modular CBT for CPTSD: A Randomised Controlled Pilot Study (NCT05259592) | Danish Veterans Centre | 2021-01-05 |
| Nab-paclitaxel Combined with Bevacizumab in the Treatment of Metastatic Extrapulmonary Neuroendocrine Carcinoma (NCT04705519) | Peking University | 2021-01-05 |
| Chemotherapy and Atezolizumab for Patients With Extensive Stage Small Cell Lung Cancer (SCLC) With Untreated, Asymptomatic Brain Metastases (NCT04610684) | Jeffrey Clarke | 2021-01-05 |
| SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin in Combination With Irinotecan in Ewing Sarcoma Patients (NCT04067115) | Sarcoma Alliance for Research through Collaboration | 2021-01-05 |
| Study of Safety and Tolerability of CFZ533 in Patients With Sjögren's Syndrome (NCT04541589) | Novartis Pharmaceuticals | 2021-01-05 |
| Efficacy of Neoadjuvant Chemotherapy in Terms of DFS in Patients With Localized Digestive Neuroendocrine Carcinomas (NCT04268121) | GERCOR - Multidisciplinary Oncology Cooperative Group | 2021-01-05 |
| Low-dose Interleukin-2 in Women With Unexplained Miscarriages (NCT03970954) | Assistance Publique - Hôpitaux de Paris | 2021-01-05 |
| Efficacy of Different Toothbrushes and Hygiene Regimen (NCT04216069) | University of Nove de Julho | 2021-01-05 |
| The Safety and Preliminary Tolerability of Lyophilized Lucinactant in Adults With Coronavirus Disease 2019 (COVID-19) (NCT04389671) | Windtree Therapeutics | 2021-01-05 |
| Effect of Local Application of Simvastatin Versus Bone Powder on Implant Bone Changes (NCT06016218) | British University In Egypt | 2021-01-05 |
| Stereotactic Ablative Radiotherapy for Oligo-Progressive Non Small Cell Lung Cancer (NCT04405401) | Centre hospitalier de l'Université de Montréal (CHUM) | 2021-01-05 |
| Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma (NCT04551430) | Washington University School of Medicine | 2021-01-05 |
| Evaluation of CRS3123 vs. Oral Vancomycin in Adult Patients With Clostridioides Difficile Infection (NCT04781387) | Crestone, Inc | 2021-01-05 |
| Olaparib and Durvalumab With Carboplatin, Etoposide, and/or Radiation Therapy for the Treatment of Extensive-Stage Small Cell Lung Cancer, PRIO Trial (NCT04728230) | M.D. Anderson Cancer Center | 2021-01-05 |
| A Safety and Tolerability Study of Neural Stem Cells (NR1) in Subjects With Chronic Ischemic Subcortical Stroke (ISS) (NCT04631406) | Clarion Cells, Inc. | 2021-01-04 |
| The Influence of Probiotic Supplementation on the Severity of Anxiety and Depressive Symptoms, as Well as the Function and Composition of Gut Microbiota, Metabolic, Inflammation, and Oxidative Stress Markers in Patients With Depression (NCT05717946) | Medical University of Lodz | 2021-01-04 |
| A Study of LY3462817 in Participants With Rheumatoid Arthritis (NCT04634253) | Eli Lilly and Company | 2021-01-04 |
| Multidisciplinary Translational Approach to Investigate Mechanisms Predictors & Prevention of Persistent PTH (NCT04098250) | Mayo Clinic | 2021-01-04 |
| Neoadjuvant Toripalimab in Combination With Gemcitabine Therapy in Cisplatin Ineligible Local Advanved Bladder Cancer (NCT04553939) | Henan Cancer Hospital | 2021-01-04 |
| Clinical Phase II/III Trial of Ustekinumab to Treat Type 1 Diabetes (UST1D2) (NCT03941132) | University of British Columbia | 2021-01-04 |
| Asses the Anti-inflammatory Effects of Short Term Copaxone Therapy on Patients the Acute Decompensated Heart Failure (NCT06003972) | Hadassah Medical Organization | 2021-01-04 |
| Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory B Cell Lymphoma (NCT04715217) | Shanxi Province Cancer Hospital | 2021-01-04 |
| A Study to Assess the Safety, Tolerability, and Efficacy of IONIS-GHR-LRx Administered in Patients With Acromegaly (NCT04522180) | Ionis Pharmaceuticals, Inc. | 2021-01-04 |
| Open Label Extension Study to Assess the Safety and Long-Term Immunogenicity of ARCT-021 (NCT04728347) | Arcturus Therapeutics, Inc. | 2021-01-04 |
| A Study of Subcutaneous Blinatumomab Administration in Participants With R/R and MRD+ B-ALL (NCT04521231) | Amgen | 2021-01-04 |
| A Placebo-controlled Study of Volixibat in Subjects With Elevated Serum Bile Acids Associated With Intrahepatic Cholestasis of Pregnancy (OHANA) (NCT04718961) | Mirum Pharmaceuticals, Inc. | 2021-01-04 |
| Mechanisms of EPO-induced Hypertension (NCT03810911) | VA Office of Research and Development | 2021-01-04 |
| Neoadjuvant Therapy for Locally Advanced Colon Cancer (NCT04625803) | Zhejiang University | 2021-01-04 |
| Rivaroxaban Plus Aspirin to Manage Recurrent Venous Thromboembolic Events (NCT05515120) | Instituto Mexicano del Seguro Social | 2021-01-03 |
| Effectiveness of Niclosamide as Add-on Therapy to the Standard of Care Measures in COVID-19 Management (NCT04753619) | University of Baghdad | 2021-01-03 |
| HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis (NCT04571619) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2021-01-03 |
| Transnasal Sphenopalatine Ganglia Block for Management of Chronic Migraines in Pediatric Patients (NCT04466826) | Washington University School of Medicine | 2021-01-02 |
| Breathing Exercises and Auricular Vagus Nerve Stimulation (NCT06531954) | Istanbul Medipol University Hospital | 2021-01-02 |
| Evaluation of a New Local Drug Delivery in the Nonsurgical Treatment of Periodontitis (NCT04862819) | Wroclaw Medical University | 2021-01-02 |
| Ketofol Versus Fenofol as Procedural Sedation for Carpal Tunnel Release (NCT04686448) | Zagazig University | 2021-01-01 |
| Basil Extract (Ocimum Basilicum) in the Management of Recurrent Aphthous Stomatitis (NCT04710888) | Tanta University | 2021-01-01 |
| Oro-tracheal Intubation: Flurbiprofen Subglottic Instillation to Prevent Laryngeal Inflammation (NCT04708964) | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2021-01-01 |
| Study in Adult Ph-positive ALL (NCT04688983) | Cardiff University | 2021-01-01 |
| Pyrotinib Maleate Combined With Vinorelbine in the Treatment of HER2-positive Advanced Breast Cancer (NCT04903652) | Tianjin Medical University Cancer Institute and Hospital | 2021-01-01 |
| Efficacy and Safety of Two Doses of Hipnos in the Treatment of Adults With Insomnia (NCT03814135) | EMS | 2021-01-01 |
| A Multi-Cancer, Multi-State, Platform Study of Durvalumab (MEDI4736) and Oleclumab (MEDI9447) in Pancreatic Adenocarcinoma, Non-Small Cell Lung Cancer and Squamous Cell Carcinoma of the Head and Neck to Correlate Clinical, Molecular and Immunologic Parameters With DNA Methylation (NCT04262388) | University Health Network, Toronto | 2021-01-01 |
| Eculizumab to Cemdisiran Switch in aHUS (NCT03999840) | Mario Negri Institute for Pharmacological Research | 2021-01-01 |
| Cranberry and Quillaja on Symptoms of Uncomplicated UTI (NCT04496726) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2021-01-01 |
| Frontline Oral Arsenic Trioxide for APL (NCT04687176) | The University of Hong Kong | 2021-01-01 |
| Safety and Preliminary Efficacy of ANS-6637 to Reduce Drug Craving and Harm in People With Opioid Use Disorder (NCT04169360) | University of Maryland, Baltimore | 2021-01-01 |
| Cyclophosphamide in the Treatment of Refractory Proliferative Arachnoiditis in CNS Tuberculosis (NCT04620772) | All India Institute of Medical Sciences | 2021-01-01 |
| The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density (NCT04630964) | Section for Affective Disorders; Northern Stockholm Psychiatry | 2021-01-01 |
| Effect of Subcutaneous Polyvidone Collagen Treatment on Hand Recovery in Adult Rheumatoid Arthritis. (NCT06656169) | Instituto Mexicano del Seguro Social | 2021-01-01 |
| 5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer. (NCT04689347) | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | 2021-01-01 |
| Viral Specific T-cells for Treatment of COVID-19 (NCT04406064) | Children's Hospital Medical Center, Cincinnati | 2021-01-01 |
| Dexamethasone as an Adjuvant in Supraclavicular Block (NCT04345588) | Assiut University | 2021-01-01 |
| Flu-Bu-Mel Based Conditioning Regimen for Patients With Lymphoid Malignancies Undergoing Allo-HSCT (NCT04897139) | Shanghai Jiao Tong University School of Medicine | 2021-01-01 |
| Adjuvant PD-1 Antibody in Combination With Capecitabine for Patients With ICC at High-Risk of Postoperative Recurrence (NCT04782804) | Fudan University | 2021-01-01 |
| Effect of Pentoxifylline on Endothelial Dysfunction in Patients With Acute Coronary Syndrome (NCT04367935) | Ain Shams University | 2021-01-01 |
| Antiplatelet Effect of Ginkgo Diterpene Lactone Meglumine Injection in Acute Ischemic Stroke (NCT05531942) | Shanghai Yueyang Integrated Medicine Hospital | 2021-01-01 |
| Laser vs Bevacizumab Injection Alone in Treatment of Diabetic Macular Edema (NCT02229175) | University of California, San Francisco | 2021-01-01 |
| Pyrotinib, Trastuzumab And Abraxane in HER2-positive MBC With Brain Metastasis (NCT04639271) | Shandong Cancer Hospital and Institute | 2021-01-01 |
| A Prospective, Two-center, Single Arm Phase II Clinical Study to Evaluate Safety and Effectiveness of Ablation Therapy in the Treatment of Lung Cancer Presenting as Ground-glass Nodules (NCT04905056) | Shanghai Zhongshan Hospital | 2021-01-01 |
| Oxytocin to Treat PTSD (NCT04228289) | VA Office of Research and Development | 2021-01-01 |
| Anti-Epilepsy Medication Valproate Administered Via ICV Route and Catheters and Pumps for CSF Infusion (NCT04529954) | Cerebral Therapeutics LLC | 2021-01-01 |
| Tofacitinib as a GC Sparing Agent for Polymyalgia Rheumatica (NCT04799262) | RenJi Hospital | 2021-01-01 |
| PD-1 Antibody Following Preoperative Chemoradiotherapy for Locally Advanced pMMR/MSS Rectal Cancer (NCT04833387) | Sun Yat-sen University | 2021-01-01 |
| Pemetrexed and TAS-102 in Combination With Bevacizumab in Refractory Colorectal Cancer (NCT04683965) | The First Affiliated Hospital with Nanjing Medical University | 2021-01-01 |
| Zanuburutinib in Relapsed and Refractory iMCD: a Prospective, Single-center, Single-arm Trial (NCT04743687) | Peking Union Medical College Hospital | 2021-01-01 |
| Chidamide With Immunotherapy for Patients With Locally Advanced or Metastatic Urothelial Carcinoma (NCT04562311) | Sun Yat-sen University | 2021-01-01 |
| PLM60 for Peripheral T Cell Lymphoma (PTCL) (NCT03553914) | Conjupro Biotherapeutics, Inc. | 2021-01-01 |
| Zanubrutinib Combined With Tislelizumab in the Treatment of r/r PMBCL and EBV+ DLBCL (NCT04705129) | Ruijin Hospital | 2021-01-01 |
| PRETELL: PREvention of TELomere-related Complications After Lung Transplant (NCT04807309) | Brigham and Women's Hospital | 2021-01-01 |
| Neoadjuvant Chemotherapy Plus Surgery Versus Surgery First For Elderly Gastric Cancer Patients (NCT04677673) | BIRENDRA KUMAR SAH | 2021-01-01 |
| Hyperbaric Oxygen and Outcome After Below Knee Amputations (NCT04717557) | Duke University | 2021-01-01 |
| Clinical Plan of Ischemic Stroke (NCT04953663) | Peking University Third Hospital | 2021-01-01 |
| Camrelizumab Combined With SOX and/or Apatinib for Locally Advanced Gastric Cancer (NCT04792515) | First Affiliated Hospital Xi'an Jiaotong University | 2021-01-01 |
| Nab-paclitaxel in Combination With Pyrotinib in Postoperative Adjuvant Therapy for HER2-positive Breast Cancer (NCT04659499) | Peking Union Medical College Hospital | 2021-01-01 |
| Impact of Perioperative Levosimendan on Patients Undergoing Cardiac Surgery With Low Ejection Fraction (NCT06784570) | Zagazig University | 2021-01-01 |
| Role of L-Arginine Supplementation in the Treatment of Rheumatoid Arthritis (NCT04535427) | RenJi Hospital | 2021-01-01 |
| Talazoparib - Carboplatin for Recurrent High-grade Glioma With DDRd (NCT04740190) | The University of Hong Kong | 2021-01-01 |
| The Efficacy and Safety of TACE, Lenvatinib and Camrelizumab in the Treatment of BCLC Stage B/C Hepatocellular Carcinoma: a Single-arm, Single-center, Open-label Study (NCT04909866) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2021-01-01 |
| Methodology for Developing an Occlusal Appliance With CBD Active Carrier (NCT04775030) | Medical University of Silesia | 2021-01-01 |
| Selected De-escalation Radiotherapy for Postoperative Head and Neck Squamous Cell Carcinoma (NCT05476965) | Hubei Cancer Hospital | 2021-01-01 |
| SBRT for Oligo-residual NSCLC After Treatment With PD-1/PD-L1 Immune Checkpoint Inhibitors (NCT04767009) | Fudan University | 2021-01-01 |
| CNCT19 Following ASCT in Patients With Relapsed or Refractory B-cell Lymphoma (NCT04690192) | Institute of Hematology & Blood Diseases Hospital, China | 2021-01-01 |
| Effects of tDCS on Anaerobic Power of Lower Limb Muscles (NCT04467476) | Universidade Federal do Piauí | 2021-01-01 |
| Efficacy of the Mepitel® Film on the Prevention of Radiodermatitis in the Inguinal Fold. (NCT04617730) | Jules Bordet Institute | 2021-01-01 |
| HAIC Combined With Bevacizumab and Toripalimab for Advanced Hepatocellular Carcinama (NCT04627363) | Sun Yat-sen University | 2021-01-01 |
| Interdialytic Peritoneal UltraFiltration in HemoDialysis Patients (NCT04603014) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2021-01-01 |
| The Effect of Ginkgolide on Clinical Improvement of Patients With Acute Ischemic Stroke (NCT05663307) | Shanghai Yueyang Integrated Medicine Hospital | 2021-01-01 |
| Transcranial Direct Current Stimulation to Reduce Chronic Pelvic Pain in Endometriosis (NCT05231239) | Charite University, Berlin, Germany | 2021-01-01 |
| A Phase Ⅱ Study of F520 in Patients With Urothelial Carcinoma (NCT04636515) | Shandong New Time Pharmaceutical Co., LTD | 2021-01-01 |
| Defibrotide for the Treatment of Severe COVID-19 (NCT04652115) | Brigham and Women's Hospital | 2021-01-01 |
| Combined Atezolizumab and Chemotherapy (Carboplatin Plus Etoposide) in Neoadjuvant Treating Limited-Stage Small Cell Lung Cancer Patients (NCT04696939) | Shanghai Pulmonary Hospital, Shanghai, China | 2021-01-01 |