| SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma (NCT04923126) | St. Jude Children's Research Hospital | 2021-06-21 |
| Safety, Tolerability and Immunogenicity of INO-4700 for MERS-CoV in Healthy Volunteers (NCT04588428) | Inovio Pharmaceuticals | 2021-06-21 |
| Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe Trial (NCT04652908) | University of California, Davis | 2021-06-21 |
| Peri-operative Sintilimab in Combination With SOX in Locally Advanced Gastric Cancer (NCT04982939) | Tianjin Medical University Cancer Institute and Hospital | 2021-06-21 |
| The Menopause After Cancer Study (NCT04766229) | University College Dublin | 2021-06-21 |
| A Study of Human Monoclonal Antibodies, BRII-196 and BRII-198 (NCT04787211) | Brii Biosciences Limited | 2021-06-20 |
| Effectiveness of Combined Levetiracetam and Midazolam in Generalized Convulsive Status Epilepticus in Children (NCT04926844) | Sohag University | 2021-06-20 |
| Ovarian Injection of PRP (Platelet -Rich Plasma) Vs Normal Saline in Premature Ovarian Insufficiency (NCT04922398) | Ahmed Saad | 2021-06-20 |
| Infliximab in the Treatment of Patients With Severe COVID-19 Disease (NCT04922827) | Jena University Hospital | 2021-06-18 |
| DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma (NCT04920617) | ImmunoVaccine Technologies, Inc. (IMV Inc.) | 2021-06-18 |
| The Effect of Opioid-Free Anesthesia in TMJ Surgery (NCT04724759) | Massachusetts General Hospital | 2021-06-18 |
| A Trial of AK117 (Anti-CD47) in Patients With Myelodysplastic Syndrome (NCT04900350) | Akeso | 2021-06-18 |
| A Phase II Study of Hepalatide in Subjects With Chronic Hepatitis B (NCT04426968) | Shanghai HEP Pharmaceutical Co., Ltd. | 2021-06-18 |
| A Long-Term Extension Study to Evaluate the Immunogenicity and Safety of Cytomegalovirus (CMV) mRNA-1647 Vaccine (NCT04975893) | ModernaTX, Inc. | 2021-06-18 |
| Apomorphine in Severe Brain-injured Patients (NCT05213169) | University of Liege | 2021-06-18 |
| Gene Therapy Clinical Trial for the Treatment Of Leber's HereDitary Optic Neuropathy (NCT04912843) | Wuhan Neurophth Biotechnology Limited Company | 2021-06-18 |
| Evaluation of Intravenous Lidocaine and Time to Regression of the Sensory Block After Spinal Anesthesia (ELSA Trial) (NCT04741880) | Instituto Nacional de Cancer, Brazil | 2021-06-17 |
| Tislelizumab Plus Chemotherapy as First-Line Treatment for Advanced Squamous NSCLC With Brain Metastases (NCT05207904) | Sun Yat-sen University | 2021-06-17 |
| A Comparison of Postprandial Glucose After a MMTT, and the Metabolic Effects of Insulin Withdrawal in a Crossover Study in Subjects With Type 1 Diabetes (NCT04956263) | Youngene Therapeutics Inc., Ltd. | 2021-06-17 |
| Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study) (NCT04715022) | University of Kansas Medical Center | 2021-06-17 |
| Neoadjuvant Therapy With Proxalutamide Combined With Androgen Deprivation Therapy（ADT）for High Risk Prostate Cancer (NCT05076851) | Hongqian Guo | 2021-06-17 |
| A Study for Evaluation of BIV201 to Reduce Ascites and Complications in Patients With Cirrhosis and Refractory Ascites (NCT04112199) | BioVie Inc. | 2021-06-17 |
| A Study to Test Whether BI 767551 Can Prevent COVID-19 in People Who Have Been Exposed to SARS-CoV-2 (NCT04894474) | Boehringer Ingelheim | 2021-06-17 |
| A Study to Assess the Safety, Efficacy, and Pharmacokinetics of Multiple Doses of ION224 (NCT04932512) | Ionis Pharmaceuticals, Inc. | 2021-06-17 |
| Phase 2 Clinical Trial to Evaluate OC-01 Nasal Spray in Subjects With Neurotrophic Keratopathy (NCT04957758) | Oyster Point Pharma, Inc. | 2021-06-17 |
| Neoadjuvant Immune Checkpoint Inhibitor Treatment in Urothelial Cancer (NCT04624399) | Queen Mary University of London | 2021-06-17 |
| A Study to Evaluate CBP-201, Rademikibart, in Adult Patients With Chronic Rhinosinusitis With Nasal Polyps (NCT04783389) | Connect Biopharm LLC | 2021-06-16 |
| Fulvestrant Plus Anlotinib in HR(+)/HER2(-) Metastatic Breast Cancer With FGFR Mutation (NCT04936295) | Sun Yat-sen University | 2021-06-16 |
| Atezolizumab Plus Induction Chemotherapy Plus CT-radiotherapy. (APOLO) (NCT04776447) | Fundación GECP | 2021-06-16 |
| Sterile Amniotic Fluid Filtrate Epidural Injection. (NCT04537026) | University of Utah | 2021-06-16 |
| MGTA-145 + Plerixafor in the Mobilization of HSCs for Allogeneic Transplant in Hematologic Malignancies (NCT04762875) | Ensoma | 2021-06-16 |
| Poziotinib and Ramucirumab for the Treatment of EGFR Exon 20 Mutant Stage IV Non-small Cell Lung Cancer (NCT05045404) | M.D. Anderson Cancer Center | 2021-06-16 |
| Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer (NCT04660760) | Academic and Community Cancer Research United | 2021-06-16 |
| 68Ga-PSMA-11 PET/CT for the Diagnosis of Bone Metastases in Patients With Prostate Cancer and Biochemical Progression During Androgen Deprivation Therapy (NCT04928820) | Jonsson Comprehensive Cancer Center | 2021-06-16 |
| Assessing the Pharmacokinetics, Safety, Tolerability and Efficacy of Continuous Oral Levodopa Via the DopaFuse® Delivery System in Parkinson's Disease Patients (NCT04778176) | SynAgile Corporation | 2021-06-16 |
| Octreotide Treatment to Improve Nutritional Recovery After Surgery for Patients with Esophageal or Gastric Cancer (NCT04871204) | Fredrik Klevebro | 2021-06-16 |
| Meglimine Sodium Succinate for Correction of Metabolic Acidosis in Critically Ill Patients (NCT05147051) | POLYSAN Scientific & Technological Pharmaceutical Company | 2021-06-16 |
| Sequential Treatment With GEMBRAX and Then FOLFIRINOX Followed by Stereotactic MRI-guided Radiotherapy in Patients With Locally Advanced Pancreatic Cancer (NCT04570943) | Institut du Cancer de Montpellier - Val d'Aurelle | 2021-06-16 |
| Pembrolizumab Plus Ramucirumab in Metastatic Gastric Cancer (NCT04632459) | Samsung Medical Center | 2021-06-16 |
| Neoadjuvant Safety of Sintilimab + XELOX + Bevacizumab in PMMR/MSS CRLM Patients (NCT04940546) | Sun Yat-sen University | 2021-06-16 |
| The Effect of Metformin in Patients With Newly Diagnosed mHSPC (NCT04925063) | Sun Yat-sen University | 2021-06-16 |
| Efficacy of Low-dose Interleukin-2 Treatment in Chronic Spontaneous Urticaria (NCT04893980) | Second Xiangya Hospital of Central South University | 2021-06-16 |
| ATEMPT 2.0: Adjuvant T-DM1 vs TH (NCT04893109) | Dana-Farber Cancer Institute | 2021-06-16 |
| N-ACETYLCYSTEINE FOR THROMBOLYSIS IN ACUTE STROKE (NCT04920448) | University Hospital, Caen | 2021-06-16 |
| Reactogenicity, Safety and Immunogenicity of QazCoVac-P COVID-19 Vaccine (NCT04930003) | Research Institute for Biological Safety Problems | 2021-06-15 |
| Immune Checkpoint Inhibitor M7824 and the Immunocytokine M9241 in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Advanced Pancreas Cancer (NCT04327986) | National Cancer Institute (NCI) | 2021-06-15 |
| A Trial Evaluating the Activity and Safety of Combination Between Cabozantinib and Temozolomide in Lung and GEP-NENS Progressive After Everolimus, Sunitinib or PRRT (CABOTEM) (NCT04893785) | National Cancer Institute, Naples | 2021-06-15 |
| Testing Miglustat Administration in Subjects With Spastic Paraplegia 11 (NCT04768166) | IRCCS Fondazione Stella Maris | 2021-06-15 |
| Neratinib and Trastuzumab Biosimilar in Patients with HER2 Mutated Advanced Solid Cancers (NCT06083662) | Korea University Guro Hospital | 2021-06-15 |
| A Clinical Trial to Assess Subjects With Dry Eye Disease. (NCT04971031) | Aldeyra Therapeutics, Inc. | 2021-06-15 |
| RBM-007 in Treatment naïve Exudative Age-related Macular Degeneration (NCT04895293) | Maturi, Raj K., M.D., P.C. | 2021-06-15 |
| Efficacy and Safety of RZL-012 on Submental Fat Reduction (NCT04867434) | Raziel Therapeutics Ltd. | 2021-06-15 |
| A Study of ADR-001 in Patients With Severe Pneumonia Caused by SARS-CoV-2 Infection (COVID-19) (NCT04888949) | Rohto Pharmaceutical Co., Ltd. | 2021-06-15 |
| Study of Camrelizumab Plus Chemotherapy as Neoadjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC) (NCT04907344) | Tianjin Medical University Cancer Institute and Hospital | 2021-06-15 |
| Memantine in Body Focused Repetitive Behaviors (NCT04792645) | University of Chicago | 2021-06-15 |
| The Effectiveness of Spermotrend Food Supplement in the Treatment of Male Infertility (NCT05222841) | Catalysis SL | 2021-06-15 |
| Efficacy of Injectable Fentanyl in Sublingual Route Versus Oral Morphine Syrup for Breakthrough Pain (NCT05037539) | Department of Medical Services Ministry of Public Health of Thailand | 2021-06-15 |
| Homologous vs Heterologous Third Vaccination in Kidney Transplant Recipients Kidney Transplant Recipients (NCT05324319) | Medical University of Vienna | 2021-06-15 |
| Mutation-specific Therapy for the Long QT Syndrome (NCT04581408) | Istituto Auxologico Italiano | 2021-06-15 |
| A Study of TQB2450 in Combination With Intensity-modulated Radiotherapy in Patients With Inoperable Locally Recurrent Nasopharyngeal Carcinoma (NCT04895345) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2021-06-15 |
| CD24Fc With Ipilimumab and Nivolumab to Decrease irAE (CINDI) (NCT04060407) | Oncoimmune, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2021-06-15 |
| A Roll-over Study to Provide Continued Treatment With Lyophilized Pegaspargase (S95014) in Pediatric Patients With Acute Lymphoblastic Leukemia (ALL) (NCT04956666) | Institut de Recherches Internationales Servier | 2021-06-15 |
| Retrobulbar Methylprednisolone as Adjunctive Treatment in Optic Neuritis Trial (NCT04942002) | Asociación para Evitar la Ceguera en México | 2021-06-15 |
| Liposomal Irinotecan, S-1, and Oxaliplatin in Advanced Pancreatic Adenocarcinoma (NCT04662112) | Asan Medical Center | 2021-06-15 |
| NCCH2006/MK010 Trial (FORTUNE Trial) (NCT04962867) | National Cancer Center, Japan | 2021-06-15 |
| A Study to Evaluate the Safety, Tolerability, and Efficacy of IMB-1018972 in Patients With Non-obstructive Hypertrophic Cardiomyopathy Trial (NCT04826185) | Imbria Pharmaceuticals, Inc. | 2021-06-14 |
| Treatment of Respiratory Complications Associated With COVID-19 Using Umbilical Cord Mesenchymal Stromal Cells (NCT04869397) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2021-06-14 |
| Initial Dual Oral Combination Therapy Versus Standard-of-care Initial Oral Monotherapy Prior to Balloon Pulmonary Angioplasty in Patients With Inoperable Chronic Thromboembolic Pulmonary Hypertension (NCT04780932) | Assistance Publique - Hôpitaux de Paris | 2021-06-14 |
| A Study on the Safety, Effectiveness and Immune Response of Meningococcal Combined ABCWY Vaccine in Healthy Adolescents and Adults (NCT04886154) | GlaxoSmithKline | 2021-06-14 |
| Metabolic Balance Study of Apraglutide in Patients With Short Bowel Syndrome, Intestinal Failure (SBS-IF) and Colon-in-Continuity (CIC) (NCT04964986) | VectivBio AG | 2021-06-14 |
| Using Vitamin D to Reduce Oral Mucosal Inflammation in Chemotherapy Patients With Oral Squamous Cell Carcinoma (NCT06016400) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2021-06-14 |
| VIBRANT Study of Vurolenatide in Adult Patients With Short Bowel Syndrome. (NCT04988997) | 9 Meters Biopharma, Inc. | 2021-06-14 |
| Strategies to Reduce Mortality Among HIV-infected and HIV-exposed Children Admitted With Severe Acute Malnutrition (NCT05051163) | Makerere University | 2021-06-14 |
| Combination of Durvalumab and BVAC-C in Patients With HPV 16 or 18 Positive Cervical Cancer Failure to First-Line Platinum-based Chemotherapy (NCT04800978) | Samsung Medical Center | 2021-06-14 |
| Evaluation of the Safety and Tolerability of KH001 in Dentin Hypersensitivity Patients (NCT04804514) | HysensBio Co., Ltd | 2021-06-14 |
| Effects of 100% Medical Grade Manuka Honey on Tympanic Membrane Reconstruction Healing. (NCT05605262) | Fakultas Kedokteran Universitas Indonesia | 2021-06-13 |
| Taurine Effect on Glycemic, Lipidic and Inflammatory Profile in Individuals With Type 2 Diabetes (NCT04874012) | Hospital de Clinicas de Porto Alegre | 2021-06-12 |
| Efficacy and Safety of Orally Administered BBT-401-1S in Subjects With Ulcerative Colitis (NCT04596293) | Bridge Biotherapeutics, Inc. | 2021-06-11 |
| A Study of Mitoxantrone Hydrochloride Liposome Injection in Patients With Advanced HER2 Negative Breast Cancer (NCT04927481) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2021-06-11 |
| Blinatumomab for Treatment of R/R or MRD-positive CD19-Positive MPAL (NCT04827745) | University of Maryland, Baltimore | 2021-06-11 |
| The Role of 68Ga-PSMA-11 PET (Prostate Specific Membrane Antigen) in Surgery Guidance in Prostate Cancer (NCT04936334) | Clinton Bahler | 2021-06-11 |
| Study to Compare the Safety and Efficacy of IDP-126 Gel to Epiduo® Forte Gel and Vehicle Gel (NCT04892706) | Bausch Health Americas, Inc. | 2021-06-11 |
| Nicotinamide Riboside in SARS-CoV-2 (COVID-19) Patients for Renal Protection (NCT04818216) | The University of Texas Health Science Center at San Antonio | 2021-06-11 |
| Olaparib and Bevacizumab in Relapsed Small Cell Lung Cancer Subjects (NCT04939662) | Se-Hoon Lee | 2021-06-11 |
| Uproleselan, Cladribine, and Low Dose Cytarabine for the Treatment of Patients With Treated Secondary Acute Myeloid Leukemia (NCT04848974) | M.D. Anderson Cancer Center | 2021-06-11 |
| Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction Ca (NCT04921904) | Baylor Research Institute | 2021-06-11 |
| Study of Valemetostat Tosylate as a Single Agent in Patients With Relapse/Refractory B-cell Lymphoma (NCT04842877) | The Lymphoma Academic Research Organisation | 2021-06-11 |
| Antidepressant Effects of TS-161 in Treatment-Resistant Depression (NCT04821271) | National Institute of Mental Health (NIMH) | 2021-06-10 |
| Study of Roxadustat in the Treatment of Acute Myocardial Infarction (NCT04803864) | Ruijin Hospital | 2021-06-10 |
| A Phase II Trial of Cabozantinib With Patients With Refractory GCTs (NCT04876456) | Jennifer King | 2021-06-10 |
| Efficacy and Safety of QiShen YiQi Dripping Pills in Chronic Heart Failure (NCT04983043) | Tasly Pharmaceutical Group Co., Ltd | 2021-06-10 |
| Migraine Manager (R01) (NCT04567355) | Children's Hospital Medical Center, Cincinnati | 2021-06-10 |
| FM101 Efficacy Study in Adults With Nonalcoholic Fatty Liver Disease or Nonalcoholic Steatohepatitis (NCT04710524) | Future Medicine | 2021-06-10 |
| Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression (NCT04670081) | Central Institute of Mental Health, Mannheim | 2021-06-10 |
| Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents (NCT04739800) | National Cancer Institute (NCI) | 2021-06-10 |
| Study of EMB-001 as a Potential Smoking Cessation Treatment (NCT04933916) | Embera NeuroTherapeutics, Inc. | 2021-06-10 |
| Study of Dara-Pembro for Multiple Myeloma Patients (NCT04361851) | Wake Forest University Health Sciences | 2021-06-09 |
| FY15-14: Tularemia Vaccine Protocol (NDBR Lot 4) (NCT03867162) | U.S. Army Medical Research and Development Command | 2021-06-09 |
| Vivitrol Treatment for Cannabis Use Disorder (NCT04139668) | Centre for Addiction and Mental Health | 2021-06-09 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral GB2064 in Participants With Myelofibrosis (NCT04679870) | Galecto Biotech AB | 2021-06-09 |