| TUC3PII-01_TU2670 Phase IIa Clinical Study (NCT05138562) | TiumBio Co., Ltd. | 2021-08-19 |
| Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition (NCT05231798) | Vanderbilt University Medical Center | 2021-08-19 |
| Treatment of Newly Diagnosed Patient's With Wilm's Tumor Requiring Abdominal Radiation Delivered With Proton Beam Irradiation (NCT04968990) | St. Jude Children's Research Hospital | 2021-08-19 |
| To Assess the Safety and Tolerability of INCB000928 in Participants With Myelodysplastic Syndromes or Multiple Myeloma (NCT04582539) | Incyte Corporation | 2021-08-19 |
| Study to Evaluate Efficacy of OLX10010 in Reducing Recurrence of Hypertrophic Scarring After Scar Revision Surgery (NCT04877756) | Olix Pharmaceuticals, Inc. | 2021-08-19 |
| Efficacy and Safety of Carfilzomib in Combination With Ibrutinib vs Ibrutinib in Waldenström's Macroglobulinemia (NCT04263480) | Christian Buske | 2021-08-18 |
| A Clinical Study of TQB3616 Capsules Combined With Anlotinib Hydrochloride Capsules or Standard Chemotherapy Second-line and Above in the Treatment of Advanced Lung Cancer (NCT04924192) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2021-08-18 |
| A Study To Assess Adverse Events and Change in Disease Activity With Oral Cariprazine When Added to Antidepressant Therapies (ADTs) Compared to Placebo in Adult Participants With Generalized Anxiety Disorder (GAD) Who Have Had an Inadequate Response to ADTs Alone (NCT04965272) | AbbVie | 2021-08-18 |
| Management of Severe Acute Malnutrition in SCD, in Northern Nigeria (NCT03634488) | Vanderbilt University Medical Center | 2021-08-18 |
| Selinexor With Alternating Bortezomib or Lenalidomide Plus Dexamethasone in TIE Newly Diagnosed MM Patients (NCT04717700) | Ida Bruun Kristensen | 2021-08-18 |
| Saroglitazar Magnesium for the Treatment of Nonalcoholic Steatohepatitis With Fibrosis (NCT05011305) | Zydus Therapeutics Inc. | 2021-08-18 |
| Efficacy and Safety Study of BDB-001 Injection in Patients With Moderate to Severe Hidradenitis Suppurativa (HS) (NCT05093855) | Staidson (Beijing) Biopharmaceuticals Co., Ltd | 2021-08-18 |
| Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients (NCT04844866) | Miltenyi Biomedicine GmbH | 2021-08-18 |
| SER150 vs Placebo in Diabetic Kidney Disease (NCT04881123) | Serodus AS | 2021-08-18 |
| Electrical Stimulation for Critically Ill Post-Covid-19 Patients (NCT05198466) | Baylor College of Medicine | 2021-08-18 |
| A Clinical Trial of GSK3640254 + Dolutegravir (DTG) in Human Immunodeficiency Virus-1 Infected Treatment-naive Adults (NCT04900038) | ViiV Healthcare | 2021-08-18 |
| Allogeneic ABCB5-positive Dermal Mesenchymal Stromal Cells for Treatment of CVU (Phase IIb) (NCT04971161) | RHEACELL GmbH & Co. KG | 2021-08-18 |
| An add-on Study to the FIGARO-DKD Study Called FIGARO-BM to Learn About the Link Between Biomarkers (Substances in the Blood Used as Indicators of Biological Processes, Disease Processes or Responses to Medication) and Finerenone in FIGARO-DKD Participants (NCT05013008) | Bayer | 2021-08-18 |
| Levosimendan in Patients With Impaired Right Ventricular Function Undergoing Cardiac Surgery (NCT05063370) | Ain Shams University | 2021-08-18 |
| Repeated iTBS Cycloserine Motor Plasticity (NCT05081986) | University of Calgary | 2021-08-18 |
| Pembrolizumab Plus Lenvatinib in Combination With Belzutifan in Solid Tumors (MK-6482-016) (NCT04976634) | Merck Sharp & Dohme LLC | 2021-08-18 |
| DISulfiram for COvid-19 (DISCO) Trial (NCT04485130) | University of California, San Francisco | 2021-08-18 |
| Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder (NCT04234191) | University of British Columbia | 2021-08-18 |
| Phase II, Single-arm Exploratory Clinical Study of Tislelizumab Combined With Anlotinib in the Treatment of Advanced Pulmonary Pleomorphic Carcinoma (NCT05375734) | Second Affiliated Hospital of Nanchang University | 2021-08-17 |
| Frontline Treatment of Follicular Lymphoma With AtezolizUmab and Obinutuzumab With and Without RadiOtherapy (NCT04962126) | Olivia Newton-John Cancer Research Institute | 2021-08-17 |
| A Single Dose Pharmaco-Diagnostic for Peripheral Nerve Continuity After Trauma (NCT04026568) | Milton S. Hershey Medical Center | 2021-08-17 |
| Safety and Clinical Activity of Nivatrotamab in Relapsed/Recurrent Metastatic Small-cell Lung Cancer (NCT04750239) | Y-mAbs Therapeutics | 2021-08-17 |
| A Study to Evaluate the Efficacy of Oral AKST4290 in Participants With Moderately Severe to Severe Diabetic Retinopathy (CAPRI) (NCT05038020) | Alkahest, Inc. | 2021-08-17 |
| Propranolol and Pembrolizumab in Advanced Soft Tissue Sarcoma Patients (NCT05961761) | Niels Junker | 2021-08-17 |
| A Study of BMS-986166 or Branebrutinib for the Treatment of Participants With Atopic Dermatitis (NCT05014438) | Bristol-Myers Squibb | 2021-08-17 |
| COVID-19 VAX Booster Dosing in Patients With Hematologic Malignancies (NCT05028374) | Barbara Ann Karmanos Cancer Institute | 2021-08-17 |
| Tolerogenic Dendritic Cell Therapy for Rheumatoid Arthritis (NCT05251870) | UMC Utrecht | 2021-08-17 |
| Futibatinib and Pembrolizumab for Treatment of Advanced or Metastatic FGF19 Positive BCLC Stage A, B, or C Liver Cancer (NCT04828486) | Mayo Clinic | 2021-08-17 |
| PTX-COVID19-B, an mRNA Humoral Vaccine, Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Demonstrate the Safety, Tolerability, and Immunogenicity of PTX-COVID19-B in Comparison to the Pfizer-BioNTech COVID-19 Vaccine. (NCT05175742) | Providence Therapeutics Holdings Inc. | 2021-08-17 |
| Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide (NCT04335682) | Alliance Foundation Trials, LLC. | 2021-08-17 |
| Chemotherapy Combined with ICIs in First-line Alectinib Failed Patients with ALK-rearranged NSCLC (NCT04997382) | Hunan Province Tumor Hospital | 2021-08-17 |
| Study of Tislelizumab in Participants With Resectable Esophageal Squamous Cell Carcinoma (NCT04974047) | BeiGene | 2021-08-17 |
| A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection (NCT04706923) | SymBio Pharmaceuticals | 2021-08-16 |
| Administration of L. Paracasei 28.4 as an Adjunct to the Treatment of Periodontitis (NCT05107622) | Universidade Estadual Paulista Júlio de Mesquita Filho | 2021-08-16 |
| Sintilimab and Bevacizumab Combined With Radiotherapy for Advanced Hepatocellular Carcinoma (NCT05010434) | Sun Yat-sen University | 2021-08-16 |
| Safety and Immunogenicity Study of Recombinant Protein RBD Candidate Vaccine Against SARS-CoV-2 in Adult Healthy Volunteers (COVID-19) (NCT05007509) | Laboratorios Hipra, S.A. | 2021-08-16 |
| COMT Inhibition Among Individuals With Comorbid AUD/ADHD (NCT03904498) | University of Colorado, Denver | 2021-08-16 |
| Mogamulizumab Q4week Dosing in Participants With R/R CTCL (NCT04745234) | Kyowa Kirin, Inc. | 2021-08-16 |
| Allogeneic Mesenchymal Human Stem Cell Infusion Therapy for Endothelial DySfunctiOn in Diabetic Subjects With Symptomatic Ischemic Heart Disease. (ACESO-IHD) (NCT04776239) | Joshua M Hare | 2021-08-16 |
| IC14 for Treatment of Amyotrophic Lateral Sclerosis (NCT03508453) | Implicit Bioscience | 2021-08-15 |
| Broad-spectrum Rapid Antidote: Varespladib Oral for Snakebite (NCT04996264) | Ophirex, Inc. | 2021-08-15 |
| Study of Neoadjuvant Imprime PGG and Pembrolizumab for Stage III, Resectable Melanoma (NCT04995094) | HiberCell, Inc. | 2021-08-15 |
| PD-1 Inhibitor Combined With Neoadjuvant Chemotherapy in Subjects With Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma (NCT05007145) | Fujian Cancer Hospital | 2021-08-15 |
| Selenium as a Potential Treatment for Moderately-ill, Severely-ill, and Critically-ill COVID-19 Patients. (NCT04869579) | CHRISTUS Health | 2021-08-15 |
| Effect of Caffeine on Time to Anesthetic Emergence After Laparoscopic Cholecystectomy : Randomized-controlled Trial (NCT05079880) | Tunis University | 2021-08-15 |
| Modified Xiao-Feng Powder for Chronic Urticaria (NCT04967092) | Prof. Lin Zhixiu | 2021-08-15 |
| The ARCT-154 Self-Amplifying RNA Vaccine Efficacy Study (ARCT-154-01) (NCT05012943) | Vinbiocare Biotechnology Joint Stock Company | 2021-08-15 |
| Psilocybin Therapy for Depression and Anxiety in Parkinson's Disease (NCT04932434) | Joshua Woolley, MD, PhD | 2021-08-15 |
| Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery (NCT04995497) | Archit Sharma | 2021-08-15 |
| Comparison Between Oxycodone and Pregabalin as Preemptive Analgesia (NCT05389813) | An-Najah National University | 2021-08-15 |
| Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB) (NCT04891770) | Gilead Sciences | 2021-08-14 |
| Heterologous Prime-boost Immunization with an Aerosolised Adenovirus Type-5 Vector-based COVID-19 Vaccine (Ad5-nCoV) After Priming with an Inactivated SARS-CoV-2 Vaccine (NCT05043259) | Jiangsu Province Centers for Disease Control and Prevention | 2021-08-14 |
| mFOLFIRINOX With or Without Stereotactic Body Radiotherapy in Locally Advanced Pancreatic Adenocarcinoma (NCT04986930) | Asan Medical Center | 2021-08-14 |
| Neoadjuvant Osimertinib + Chemotherapy for EGFR-mutant Stage III NSCLC (NCT05011487) | Sun Yat-sen University | 2021-08-13 |
| A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Two Different Doses of Alpha1-Proteinase Inhibitor Subcutaneous (Human) 15% in Participants With Alpha1-Antitrypsin Deficiency (NCT04722887) | Grifols Therapeutics LLC | 2021-08-13 |
| EUS-RFA PANCARDINAL-1 Trial (NCT04990609) | The University of Texas Health Science Center, Houston | 2021-08-13 |
| COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders (NCT05000216) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-08-13 |
| Open-Label Surufatinib in European Patients With NET (NCT04579679) | Hutchmed | 2021-08-13 |
| RVU120 (SEL120) in Patients with Relapse/Refractory Metastatic or Advanced Solid Tumors (NCT05052255) | Ryvu Therapeutics SA | 2021-08-13 |
| A Study of E7820 in People With Bone Marrow (Myeloid) Cancers (NCT05024994) | Memorial Sloan Kettering Cancer Center | 2021-08-13 |
| Phase II Study of Neoadjuvant ArOMatase Inhibitor Therapy for ER+ Breast Cancer (NAOMI) (NCT04568616) | Dartmouth-Hitchcock Medical Center | 2021-08-13 |
| A Trial of AK117 (Anti-CD47 Antibody) in Patients With Acute Myeloid Leukemia (NCT04980885) | Akeso | 2021-08-13 |
| Personalized AZithromycin/metronidAZole Therapy in Pediatric Crohn's Disease (CD) (NCT04186247) | University of North Carolina, Chapel Hill | 2021-08-13 |
| Impact of Post-Traumatic Stress Disorder Treatment by Reconsolidation Therapy on Fibromyalgia Syndrome (NCT04950426) | Centre Hospitalier Henri Laborit | 2021-08-13 |
| Neoadjuvant Therapy for Localized Rectal Adenocarcinoma (NCT04418895) | UNC Lineberger Comprehensive Cancer Center | 2021-08-13 |
| Phase 2a Study of the Safety, Tolerability, and Pharmacokinetics of Topically Administered PRN473 (SAR444727) in Patients With Mild to Moderate Atopic Dermatitis (NCT04992546) | Principia Biopharma, a Sanofi Company | 2021-08-13 |
| Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients (NCT04536077) | Washington University School of Medicine | 2021-08-13 |
| A Study to Investigate the Safety, Tolerability, of APG-2575 as a Single Agent or in Combination for Breast Cancer (NCT04946864) | Ascentage Pharma Group Inc. | 2021-08-13 |
| Magnetic Resonance-guided Adaptive Stereotactic Body Radiotherapy for Hepatic Metastases (NCT05027711) | University Hospital Heidelberg | 2021-08-12 |
| Hepatic Arterial Infusion Combined With Lenvatinib and Camrelizumab for Unresectable Hepatocellular Carcinoma (NCT05003700) | Nanfang Hospital, Southern Medical University | 2021-08-12 |
| Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015) (NCT04924075) | Merck Sharp & Dohme LLC | 2021-08-12 |
| Study of TVB-2640 in Subjects With Nonalcoholic Steatohepatitis (NASH) (NCT04906421) | Sagimet Biosciences Inc. | 2021-08-12 |
| Befotertinib and Icotinib in Treatment-naive Patients With Advanced EGFR-Mutant Lung Cancer (NCT05007938) | Betta Pharmaceuticals Co., Ltd. | 2021-08-12 |
| Phase I/II Trial of Pembrolizumab and Androgen-receptor Inhibitor With or Without 225Ac-J591 for Progressive Metastatic Castration Resistant Prostate Cancer (NCT04946370) | Weill Medical College of Cornell University | 2021-08-12 |
| Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases (NCT05003986) | Travere Therapeutics, Inc. | 2021-08-12 |
| Rapamycin - Effects on Alzheimer's and Cognitive Health (NCT04629495) | The University of Texas Health Science Center at San Antonio | 2021-08-11 |
| A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With Chronic Hepatitis B and Hepatitis D Co-infection (NCT05674448) | Huahui Health | 2021-08-11 |
| A Study of Efficacy and Safety of AX-8 in Chronic Cough (NCT04866563) | Axalbion SA | 2021-08-11 |
| 177 LuPSMA-617 vs Docetaxel in Metastatic Castration Resistant and PSMA-Positive Prostate Cancer (NCT04663997) | Canadian Cancer Trials Group | 2021-08-11 |
| The Efficacy of HLX208 (BRAF V600E Inhibitor) With Cetuximab for Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation After First-line Treatment (NCT04984369) | Shanghai Henlius Biotech | 2021-08-11 |
| NDV-HXP-S Vaccine Clinical Trial (COVIVAC) (NCT05940194) | Institute of Vaccines and Medical Biologicals, Vietnam | 2021-08-11 |
| A Study of Reduced-dose Radiation in People With Metastatic Tumors With a Genetic Change (NCT05010031) | Memorial Sloan Kettering Cancer Center | 2021-08-11 |
| Study of NDI-034858 in Participants With Moderate to Severe Plaque Psoriasis (NCT04999839) | Takeda | 2021-08-11 |
| A Study in Patients With Erosive Esophagitis to Investigate Safety, Tolerability, and Healing Rates After 4 Weeks Treatment of X842 or Lansoprazole and Symptom Pattern During Subsequent 4 Weeks Treatment With Lansoprazole (NCT05055128) | Cinclus Pharma Holding AB | 2021-08-11 |
| 64Cu-SAR-bisPSMA and 67Cu-SAR-bisPSMA for Identification and Treatment of PSMA-expressing Metastatic Castrate Resistant Prostate Cancer (SECuRE) (NCT04868604) | Clarity Pharmaceuticals Ltd | 2021-08-11 |
| Treatment of CD79B Mutant Relapsed/Refractory Diffuse Large B-Cell Lymphoma With Bruton Tyrosine Kinase Inhibitor Zanubrutinib (NCT05068440) | BeiGene | 2021-08-11 |
| The Safety and Efficacy of KDR2-2 Suspension Eye Drops in the Treatment of Corneal Neovascularization (NCT05011916) | Zhongshan Ophthalmic Center, Sun Yat-sen University | 2021-08-10 |
| Neuromodulation in COVID-19 Patients (NCT04808284) | D'Or Institute for Research and Education | 2021-08-10 |
| Combination of Intranasal Scopolamine and Sensory Augmentation to Mitigate G-transition Induced Motion Sickness and Enhance Sensorimotor Performance (NCT05852730) | Repurposed Therapeutics, Inc. | 2021-08-10 |
| Camrelizumab and Chemotherapy Combined With Endoscopic Surgery for Recurrent Nasopharyngeal Carcinoma (NCT05011227) | Eye & ENT Hospital of Fudan University | 2021-08-10 |
| Booster Dose Trial (NCT05016622) | Montefiore Medical Center | 2021-08-10 |
| Clinical Study of the Safety and Immunogenicity of a Recombinant Viral Vector AAV5 (Adeno-Associated Virus Type 5 )-RBD (Receptor Binding Domain)-S Vaccine for the Prevention of Coronavirus Infection (COVID-19) (NCT05037188) | Biocad | 2021-08-10 |
| The COlchicine HypERtENsion Trial (NCT04916522) | Herlev and Gentofte Hospital | 2021-08-10 |
| COVID-19 Protection After Transplant Pilot Study (NCT04969263) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-08-10 |
| Intravenous T3011 Given as a Single Agent and in Combination With Other Therapy in Subjects With Advanced Solid Tumors (NCT04780217) | ImmVira Pharma Co. Ltd | 2021-08-10 |