| A Global Phase II/III Clinical Study to Evaluate the Efficacy and Safety of HLX43 Monotherapy or HLX43 in Combination With HLX07 Versus Docetaxel in Advanced or Metastatic Squamous Non-Small Cell Lung Cancer (NCT07459751) | Shanghai Henlius Biotech | 2026-05-27 |
| Clinical Trial to Test Efficacy of Targeting Hypoxia Combined With ARSI After First-line ARSI Therapy for Castrate Resistant Prostate Cancer (NCT06836726) | University Health Network, Toronto | 2026-05-27 |
| Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia (NCT07061951) | National Cancer Institute (NCI) | 2026-05-27 |
| Testing the Use of an IDH1 Inhibitor, Olutasidenib, in Acute Myeloid Leukemia Added to ASTX727 and Venetoclax; in High-Risk MDS Added to ASTX727; and Alone in Low Risk MDS (A MyeloMATCH Treatment Substudy) (NCT07153497) | National Cancer Institute (NCI) | 2026-05-27 |
| Short-course Radiotherapy Combined With Retlirafusp Alfa and CAPOX Chemotherapy as Neoadjuvant Therapy for Locally Advanced Rectal Cancer: A Prospective, Single-arm, Phase II Clinical Study (NCT07663071) | Harbin Medical University | 2026-05-27 |
| HL-300 Ointment in Patients With Mild-to-Moderate Atopic Dermatitis (NCT07629778) | Hangzhou Highlightll Pharmaceutical Co., Ltd | 2026-05-26 |
| Clinical Study on CAR-T Targeting Igβ Targets in Refractory Relapsed Non-Hodgkin's Lymphoma (NCT05312476) | The First Affiliated Hospital of Soochow University | 2026-05-26 |
| A Randomized Study to Evaluate the Efficacy of a Reduced Starting Dose of Lazertinib (Leclaza) and Preemtive Magnesium Supplementation to Prevent Lazertinib(Leclaza)-Induced Peripheral Neuropathy (NCT07774520) | Samsung Medical Center | 2026-05-26 |
| A Study to Evaluate JL18008 in Subject With HIV Immunological Non-Responders (NCT07579741) | Jecho Biopharmaceuticals Co., Ltd. | 2026-05-26 |
| A Clinical Trial to Evaluate agenT-797 Plus Standard of Care in Participants With Severe Pneumonia With Moderate to Severe Acute Hypoxemic Respiratory Failure (NCT07615010) | MiNK Therapeutics | 2026-05-26 |
| TROP2 CAREngineered Cord Blood-Derived NK Cells + Belzutifan In Pancreatic Cancer (NCT07377526) | M.D. Anderson Cancer Center | 2026-05-26 |
| Intratumoral N17350 in Advanced Solid Tumors (NCT07339176) | Onchilles Pharma Inc | 2026-05-25 |
| A Clinical Study of SYS6023 Combination Therapy for Advanced Breast Cancer (NCT07597629) | CSPC Megalith Biopharmaceutical Co.,Ltd. | 2026-05-25 |
| A Trial to Evaluate Safety and Efficacy of a Product Named VGN-R08b in Parkinson's Disease Patients With GBA1 Mutations (NCT07414290) | Shanghai Vitalgen BioPharma Co., Ltd. | 2026-05-25 |
| Efficacy and Safety Study of Dovramilast in People With Leprosy Type 2 Reaction (NCT07172659) | Medicines Development for Global Health | 2026-05-25 |
| HEART: Pilot Randomized Controlled Trial (NCT07483177) | Mayo Clinic | 2026-05-25 |
| The Bloom Infant Probiotic (BIP) Study (NCT07189390) | South Australian Health and Medical Research Institute | 2026-05-25 |
| A Study to Evaluate Mosunetuzumab in Participants With Systemic Lupus Erythematosus With or Without Active Lupus Nephritis (NCT07598396) | Hoffmann-La Roche | 2026-05-25 |
| Phase II Clinical Trial to Evaluate the Efficacy and Safety of SYH2070 Injection in Participants With Homozygous Familial Hypercholesterolemia (NCT07591298) | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 2026-05-24 |
| Clinical Trial of the 24-valent Pneumococcal Polysaccharide Conjugate Vaccine (CRM197/Tetanus Toxoid) (NCT07600983) | CanSino Biologics Inc. | 2026-05-24 |
| Phase II Clinical Study of the Efficacy and Safety of HSK55718 in the Treatment of Abdominal Postoperative Pain (NCT07491146) | Yingyong Zhou,MD,PhD | 2026-05-23 |
| Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD (NCT06902974) | Sunstone Medical | 2026-05-23 |
| Desloratadine as Adjunct Therapy for Rheumatoid Arthritis (NCT07632872) | Horus University | 2026-05-23 |
| Adebrelimab Combined With Neoadjuvant Chemoradiotherapy for Esophageal Squamous Cell Carcinoma (NCT07595770) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2026-05-22 |
| Ivosidenib as Maintenance Therapy in Transplant-Ineligible IDH1-mutated AML and HR-MDS (NCT07607418) | Ruijin Hospital | 2026-05-22 |
| Trial of HSK44459 Cream for the Management Plaque Psoriasis (NCT07623486) | Haisco Pharmaceutical Group Co., Ltd. | 2026-05-22 |
| Study on the Effect of Oral Diammonium Glycyrrhizinate in Attenuating Toxicity and Enhancing Efficacy of CAR-T Cell Therapy (NCT07616271) | Tongji Hospital | 2026-05-22 |
| A Clinical Trial Evaluating the Efficacy and Safety of HSK55718 in Patients for Postoperative Pain Treatment in Abdominal Surgery (NCT07533786) | Haisco Pharmaceutical Group Co., Ltd. | 2026-05-22 |
| Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally Advanced Premenopausal Hormone Receptor Positive Breast Cancer Patients (NCT07460752) | Mayo Clinic | 2026-05-22 |
| FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control (NCT07332741) | University of Illinois at Chicago | 2026-05-22 |
| A Phase II Study to Evaluate the Efficacy and Safety of Teclistamab in Combination With Daratumumab (Tec-Dara) in Newly Diagnosed Multiple Myeloma With Concurrent Light Chain Amyloidosis (MM+AL). (NCT07638683) | Shanghai Zhongshan Hospital | 2026-05-22 |
| A Study of TRC003 in the Treatment of Patients With Progressive PSMA-positive mCRPC (NCT07567521) | C Ray Therapeutics | 2026-05-22 |
| Phase1b/2 Trial Of AZA + APG1252 In Patients With High-Risk AML (NCT07508982) | M.D. Anderson Cancer Center | 2026-05-22 |
| A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD (NCT07527910) | Regeneron Pharmaceuticals | 2026-05-22 |
| A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ³¹P-MRS in Patients With Early, Untreated Parkinson's Disease (NCT07322887) | GEN İlaç ve Sağlık Ürünleri A.Ş. | 2026-05-21 |
| RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive (NCT07413939) | Hoffmann-La Roche | 2026-05-21 |
| Chinese Adults With Kidney Disease (NCT07522099) | ADARx Pharmaceuticals, Inc. | 2026-05-21 |
| Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer (NCT07027124) | Icahn School of Medicine at Mount Sinai | 2026-05-21 |
| A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma (NCT07428616) | Exelixis | 2026-05-21 |
| Intravesical Chemotherapy in Combination With Systemic Pembrolizumab in NMIBC Unresponsive or Exposed to BCG Therapy (NCT06972615) | BLATAM | 2026-05-21 |
| Safety, Tolerability, and Preliminary Effectiveness of CTH120 in Fragile X Syndrome (NCT07654114) | Connecta Therapeutics, S.L. | 2026-05-21 |
| Study of PM54 in Combination With Immunotherapy in Adult Participants With Advanced Malignancies (NCT07644039) | PharmaMar | 2026-05-21 |
| A Study of the Effect and Safety of HS-10390 in the Treatment of Participants With Chronic Kidney Disease (NCT07555054) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2026-05-21 |
| Immunoprevention for High-risk Lung Lesions (NCT07284485) | Robert Samstein | 2026-05-21 |
| Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT (NCT04520139) | University of California, Irvine | 2026-05-21 |
| EGFR-TKIs Plus PD-1 in EGFR-Mutant Advanced NSCLC (NCT07637448) | Nanfang Hospital, Southern Medical University | 2026-05-21 |
| Effects of Short-term Perioperative Daidzein Intervention on Liver Histopathology in Patients With MASLD (NCT07623044) | Eastern Hepatobiliary Surgery Hospital | 2026-05-21 |
| Novel Biomarkers of Non-IgE Immediate Hypersensitivity Drug Reactions (NCT07605806) | Johns Hopkins University | 2026-05-21 |
| ASCEND: Safety and Tolerability of ION337 for the Treatment of Dravet Syndrome (NCT07531745) | Ionis Pharmaceuticals, Inc. | 2026-05-21 |
| Minocycline After Successful Endovascular Thrombectomy Recanalization in Acute Anterior Circulation Large Vessel Occlusion (ATTRACTION-MINOA) (NCT07594314) | Xiang Luo | 2026-05-21 |
| Allopurinol in Depression (NCT07574060) | Tanta University | 2026-05-20 |
| Short-Course Radiotherapy, Nal-IRI, Capecitabine, and Camrelizumab for Locally Advanced MSS Rectal Cancer (NCT07521605) | Guangdong Provincial People's Hospital | 2026-05-20 |
| Fovinaciclib Plus Aromatase Inhibitors and Dual HER2 Blockade in a Response-Adapted Neoadjuvant Strategy for HR-Positive/HER2-Positive Early Breast Cancer (NCT07616427) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2026-05-20 |
| Conversion Therapy With FOLFOX-HAIC Plus Lenvatinib And Tislelizumab For Hepatocellular Carcinoma With Vp3 Portal Vein Tumor Thrombus (NCT07483359) | First Hospital of China Medical University | 2026-05-20 |
| Evaluating the Safety and Efficacy of PNMR as Treatment for Long COVID (NCT07627815) | ParagonClinicals Inc. | 2026-05-20 |
| Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of EVER001 in Participants With Selected Proteinuric Glomerular Diseases (NCT07614477) | Everest Medicines (China) Co.,Ltd. | 2026-05-20 |
| Study of Becotatug Vedotin Added to Standard Treatment for Advanced Bile Duct Cancer With EGFR Mutations (NCT07598318) | Sir Run Run Shaw Hospital | 2026-05-20 |
| A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7) (NCT07589595) | Eli Lilly and Company | 2026-05-20 |
| A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256) (NCT07124078) | Incyte Corporation | 2026-05-20 |
| Comparative Study of Microneedling With Topical Minoxidil 5% ± NB-UVB in Stable Vitiligo" (NCT07548918) | Sohag University | 2026-05-20 |
| Research On Nicotinamide Riboside Supplement Support in MDS (ROSS Trial) (NCT07579429) | University of Colorado, Denver | 2026-05-20 |
| A Clinical Study of Liposomal Irinotecan for Second-Line Therapy in Metastatic Colorectal Cancer (NCT07585279) | Hebei Medical University Fourth Hospital | 2026-05-20 |
| A Study of SKB571 in Participants With Gastrointestinal Tumors (NCT07564466) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2026-05-20 |
| A Study to Evaluate the Safety and Diagnostic Performance of F18 FBPA PET/CT Imaging in Solid Tumors (NCT07691775) | Heron Neutron Medical Corp. | 2026-05-20 |
| Different-Dose SCRT Plus CAPOX, PD-1 Blockade and IL-2 in LARC (NCT07646639) | The First Affiliated Hospital with Nanjing Medical University | 2026-05-20 |
| Study of Tarlatamab as Maintenance Treatment After Chemo-radiotherapy for Limited Stage SCLC Patients (NCT07242547) | Fundación GECP | 2026-05-20 |
| R-PMDT Regimen in Newly Diagnosed PCNSL (NCT07604987) | Zou Dehui | 2026-05-20 |
| Safety of Biliary Intraductal Radiofrequency Ablation in Patients With Unresectable Extrahepatic Biliary Tract Cancer (NCT06274879) | Insel Gruppe AG, University Hospital Bern | 2026-05-20 |
| GFH375 Monotherapy and Combination Therapy as First-Line Treatment for Advanced KRAS G12D-Mutant Non-Small Cell Lung Cancer (NCT07554859) | Genfleet Therapeutics (Shanghai) Inc. | 2026-05-20 |
| Phase 1/2 Study of UI-102 in Selected Advanced Cancers (NCT07605962) | United Immunity, co., Ltd. | 2026-05-20 |
| Beta-Blockers on the Efficacy of Neoadjuvant Immunotherapy for Gastric Cancer (NCT07511894) | Nanfang Hospital, Southern Medical University | 2026-05-20 |
| The DoHAICs Study Expansion Phase (NCT07584018) | Tianjin Medical University Cancer Institute and Hospital | 2026-05-20 |
| Safety and Biomarker Responses of Delgocitinib (JAK1,2,3/TYK2 Inhibitor) in Central Centrifugal Cicatricial Alopecia and Lichen Planopilaris (NCT07487948) | Icahn School of Medicine at Mount Sinai | 2026-05-19 |
| PH 2 Pemigatinib in SDH-deficient GIST (NCT07434843) | Dana-Farber Cancer Institute | 2026-05-19 |
| A Study of JADE101 in Participants With Immunoglobulin A Nephropathy (NCT07541287) | Jade Biosciences, Inc. | 2026-05-19 |
| A Clinical Trial Using Tirzepatide to Help Adults With Type 1 Diabetes Automatically Control Their Blood Sugar (NCT07284511) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2026-05-19 |
| Effect of Roflumilast as Add-On Therapy in Rheumatoid Arthritis (NCT07632846) | Horus University | 2026-05-19 |
| Minocycline After Successful Endovascular Thrombectomy Recanalization in Posterior Circulation Arterial Occlusion (ATTRACTION-MINOP) (NCT07594301) | Xiang Luo | 2026-05-19 |
| A Study to Investigate the Long-term Safety, Tolerability and Efficacy of Balinatunfib in Participants With Crohn's Disease or Ulcerative Colitis (SPECIFI-IBD-LTS) (NCT07222189) | Sanofi | 2026-05-19 |
| A Phase Ib/II Trial to Evaluate the Efficacy and Safety of HH-009 for the Treatment of FGF19-positive Advanced or Unresectable HCC (NCT07547553) | Huahui Health | 2026-05-19 |
| Phase 1b/2a Study of EYC-0305 in Patients With Neovascular Age-related Macular Degeneration (NCT07587515) | Eyconis INC. | 2026-05-19 |
| Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or Incurable Hematologic Malignancies (NCT07336238) | University of Washington | 2026-05-19 |
| Study Evaluating the Efficacy, Safety, and Tolerability of ASY202 (Dihydroergotamine Mesylate [DHE] Inhalation Powder Delivered Via a Multidose Dry Powder Inhaler) for the Acute Treatment of Migraine in Adult Patients (NCT07646613) | Aspeya, Inc. | 2026-05-19 |
| Study of Denikitug (GS-1811) Given Alone or With Nivolumab or With Chemotherapy in Adults With Advanced Colorectal Cancer (NCT07527858) | Gilead Sciences | 2026-05-19 |
| DIROXIMEL FUMARATE TO REDUCE PERIHAEMATOMAL OEDEMA IN INTRACEREBRAL HAEMORRHAGE: DOUBLE BLIND RANDOMIZED CLINICAL TRIAL (NCT07275515) | University Hospital, Lille | 2026-05-19 |
| Recombinant Human Thymosin Beta 4 for Injection(NL005) for Acute Myocardial Infarction (NCT07586865) | Beijing Northland Biotech. Co., Ltd. | 2026-05-18 |
| Study to Evaluate HM15275 in Subjects With Type 2 Diabetes Mellitus (NCT07527650) | Hanmi Pharmaceutical Company Limited | 2026-05-18 |
| First-in-Human Study to Evaluate AZD8359 STEAP2 TCE in Participants With Prostate Cancer (NCT07529717) | AstraZeneca | 2026-05-18 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Clinical Activity of ABS-1230 in Pediatric and Young Adult Participants With KCNT1-related Epilepsy (NCT07600736) | Actio Biosciences, Inc. | 2026-05-18 |
| FMT for Pediatric SR-aGVHD (NCT07602751) | Bambino Gesù Hospital and Research Institute | 2026-05-18 |
| Evaluating the Effectiveness of the Common Elements Treatment Approach (CETA) in Peru: Mechanisms of Individual and Intergenerational Change (NCT07667738) | University of Notre Dame | 2026-05-18 |
| Imlunestrant and Abemaciclib for the Treatment of Estrogen Receptor Positive Breast Cancer in Patients With Minimal Residual Disease, MIRI Trial (NCT07191717) | Jonsson Comprehensive Cancer Center | 2026-05-18 |
| Study of [212Pb]Pb-DOTAM-MAM279 ([212Pb]Pb-MP0712) in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors (NCT07278479) | Molecular Partners AG | 2026-05-18 |
| A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005) (NCT07570173) | Merck Sharp & Dohme LLC | 2026-05-18 |
| Ph. I/II Sodium Thiosulfate for OtoProtection During Cisplatin (STOP-CIS) (NCT07407582) | University of Arizona | 2026-05-18 |
| MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder (NCT07118839) | VA Office of Research and Development | 2026-05-18 |
| Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV (NCT06705478) | National Institute of Allergy and Infectious Diseases (NIAID) | 2026-05-17 |
| A Study of TAK-755 in Adults With Acute Ischemic Stroke (NCT07392450) | Takeda | 2026-05-17 |
| [18F]F-AraG PET Imaging in Alzheimer's Disease (NCT07611357) | CellSight Technologies, Inc. | 2026-05-16 |
| Xiaochaihu Granules for Depression After Allogeneic Hematopoietic Stem Cell Transplantation (NCT07608029) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2026-05-16 |