| Venetoclax and Eprenetapopt for the Treatment of Relapsed of Refractory Mantle Cell Lymphoma (NCT04990778) | M.D. Anderson Cancer Center | 2021-11-30 |
| Stereotactic Radiation & Abemaciclib in the Management of HR+/HER2- Breast Cancer Brain Metastases (NCT04923542) | H. Lee Moffitt Cancer Center and Research Institute | 2021-11-30 |
| A Phase Ib/II Clinical Study of LBL-007 in Combination With Toripalimab in Treatment of Advanced Malignant Tumors (NCT05102006) | Nanjing Leads Biolabs Co.,Ltd | 2021-11-30 |
| SI-B001 as a Single Agent or in Combination With Chemotherapy in the Treatment of Digestive System Malignancies (NCT05039944) | Sichuan Baili Pharmaceutical Co., Ltd. | 2021-11-30 |
| Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (NCT04862650) | Marcelo Bonomi | 2021-11-30 |
| Study of Tisagenlecleucel in Chinese Pediatric and Young Adult Subjects With Relapsed or Refractory B-cell ALL (NCT04156659) | Novartis Pharmaceuticals | 2021-11-30 |
| VTX002 Versus Placebo for the Treatment of Moderately to Severely Active Ulcerative Colitis (NCT05156125) | Oppilan Pharma Ltd | 2021-11-30 |
| The Study of CM310 in Patients With Chronic Rhinosinusitis With Nasal Polyps (NCT05131464) | Keymed Biosciences Co.Ltd | 2021-11-30 |
| (HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis (NCT04910685) | Blueprint Medicines Corporation | 2021-11-30 |
| A Multi-cohort Study of Safety, Efficacy, PK and PD of GNR-055 in Patients With Mucopolysaccharidosis Type II (NCT05208281) | AO GENERIUM | 2021-11-30 |
| Pinpoint Trial: Prebiotics IN Peanut Oral ImmunoTherapy (NCT05138757) | University of Chicago | 2021-11-30 |
| Camrelizumab Combined With CD30 CAR-T in the Treatment of Relapsed/Refractory CD30+ Lymphoma (NCT05320081) | Huazhong University of Science and Technology | 2021-11-30 |
| The Immune Response of Heterologous Boost Third Dose of mRNA and Protein COVID-19 Vaccine (NCT05132855) | Chang Gung Memorial Hospital | 2021-11-30 |
| Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas (NCT04750928) | National Cancer Institute (NCI) | 2021-11-29 |
| Efficacy, Safety, and Tolerability, of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis (NCT05152173) | Endo USA Inc., a Keenova Therapeutics Company | 2021-11-29 |
| SABRE: A Single-arm Prospective Study Measuring Safety and Tolerability of SARS-CoV-2 Neutralising Antibodies in High-risk Populations (NCT05393999) | Imperial College Healthcare NHS Trust | 2021-11-29 |
| Multiparametric Assessment of Bone Response in mCRPC Patients Treated With Cabozantinib (NCT05265988) | Alfredo Berruti | 2021-11-29 |
| Niraparib and Dostarlimab in HRD Solid Tumors (NCT04983745) | West Cancer Center | 2021-11-29 |
| Parallel Arm Trial of AD109 and AD504 In Patients With OSA (NCT05071612) | Apnimed | 2021-11-29 |
| Megestrol Acetate Compared With Megestrol Acetate and Metformin to Prevent Endometrial Cancer (NCT04576104) | Northwestern University | 2021-11-29 |
| A Study on the Safety, Tolerability and Immune Response of Meningococcal Combined ABCWY Vaccine in Healthy Infants (NCT05082285) | GlaxoSmithKline | 2021-11-29 |
| A Research Study Looking at How Well a Combination of the Medicines Semaglutide and NNC0480-0389 Works in People With Type 2 Diabetes (NCT05144984) | Novo Nordisk A/S | 2021-11-29 |
| The Effectiveness of a Topical Palmitoylethanolamide (PEA) Formulation (Levagen+) for Reducing Symptoms of Eczema (NCT05003453) | RDC Clinical Pty Ltd | 2021-11-29 |
| Evaluation of New Diagnostic Tool Using Fluorescence to Detect High-grade Vulvar Intraepithelial Neoplasia (NCT05104099) | Institut de Cancérologie de Lorraine | 2021-11-29 |
| MicroRNA Profiles in Triple Negative Breast Cancer (NCT04771871) | University College Hospital, Ibadan | 2021-11-29 |
| Heart Rate Variability Biofeedback for Smoking Cessation Treatment (NCT05224050) | Rutgers, The State University of New Jersey | 2021-11-29 |
| A Study To Assess the Adverse Effects and Change in Condition of OnabotulinumtoxinA X Injection in Adult Participants With Forehead Lines (NCT05152576) | Allergan | 2021-11-29 |
| Extending the Time Window for Tenecteplase by Recanalization of Basilar Artery Occlusion in Posterior Circulation Stroke (NCT05105633) | University of Melbourne | 2021-11-29 |
| 68Ga-P16-093 PET/CT Imaging in Glioma Patients (NCT05569434) | Peking Union Medical College Hospital | 2021-11-28 |
| A 6-month Study to Evaluate Sulforaphane Effects in PD Patients (NCT05084365) | Central South University | 2021-11-28 |
| iTBS-DCS in Obsessive Compulsive Disorder (NCT05177601) | University of Calgary | 2021-11-26 |
| RC48 for Neoadjuvant Chemotherapy of HER2 Positive Breast Cancer (NCT05134519) | Xijing Hospital | 2021-11-26 |
| Efficacy Study of Daily Administration of VPA in Patients Affected by Wolfram Syndrome (NCT04940572) | Centre d'Etude des Cellules Souches | 2021-11-26 |
| Evaluation of the Tolerance, Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of MIL62 Injection for Treating Lupus Nephritis (NCT07044115) | Beijing Mabworks Biotech Co., Ltd. | 2021-11-26 |
| Study Evaluating the Tailored Management of Locally-advanced Rectal Carcinoma (NCT04749108) | Institut du Cancer de Montpellier - Val d'Aurelle | 2021-11-26 |
| Study of LM-302 in Patients With Advance Solid Tumors (NCT05161390) | LaNova Medicines Zhejiang Co., Ltd. | 2021-11-26 |
| Clinical Trial to Assess the Safety and Efficacy of Investigational Product in Patients Due to Hypospadias Treatment Failure (NCT05093166) | Holostem s.r.l. | 2021-11-26 |
| Intravitreal Infliximab for Proliferative Vitreoretinopathy (NCT04891991) | Cairo University | 2021-11-26 |
| 3K3A-APC for Treatment of Amyotrophic Lateral Sclerosis (ALS) (NCT05039268) | Macquarie University, Australia | 2021-11-25 |
| Study to Assess the Efficacy and Safety of Favipiravir-HU (NCT04940871) | University of Pecs | 2021-11-25 |
| Effect of Ivabradine on Microcirculation and Cardiac Output in Septic Shock Patients (NCT05141071) | Cairo University | 2021-11-25 |
| Treat Malignant Ascites Caused by Gastrointestinal or Ovarian Cancer With M701 Bispecific Antibody (NCT06266091) | Wuhan YZY Biopharma Co., Ltd. | 2021-11-24 |
| Evaluation of Neratinib for Treatment and Prevention of Subsequent CNS Event(s) in Patients With Brain Metastasis of Advanced HER2 Positive Breast Cancer (NCT04856475) | Jules Bordet Institute | 2021-11-24 |
| Study of CDK4/6 Inhibitor Combined With PD-L1 Monoclonal Antibody in the Treatment of PD-1/PD-L1 Resistance and Abnormal Cell Cycle Digestive System Tumors (NCT05139082) | Peking University | 2021-11-24 |
| Active Myeloid Target Compound Combinations in MDS/MPN Overlap Syndromes Overlap Syndromes (ABNL-MARRO) (NCT04061421) | Michael Savona | 2021-11-24 |
| Local Triamcinolone Injection Combined With Fibrin Glue Spray in Preventing Esophageal Stricture After Big-range Endoscopic Submucosal Dissection for Esophageal Early Cancer (NCT06840561) | Sun Yat-Sen University Cancer Center | 2021-11-24 |
| Bacteriophage Therapy in Patients With Diabetic Foot Osteomyelitis (NCT05177107) | Adaptive Phage Therapeutics, Inc. | 2021-11-24 |
| Randomized Double-Blind Phase 2 Efficacy and Safety of Autologous HB-MSCs vs Placebo for Treatment of Multiple Sclerosis (NCT05116540) | Hope Biosciences Research Foundation | 2021-11-24 |
| Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease Pain (NCT04906447) | University of Illinois at Chicago | 2021-11-24 |
| Rilzabrutinib for the Treatment of Chronic Spontaneous Urticaria in Patients Who Remain Symptomatic Despite the Use of H1 Antihistamine (NCT05107115) | Sanofi | 2021-11-24 |
| Management of Cerebral Vascular Spasm in Posttraumatic Subarachnoid Hemorrhage Using Combination Therapy (NCT05131867) | Zagazig University | 2021-11-24 |
| A Safety and Efficacy Study of FCR001 in Adults With Rapidly Progressive Diffuse Cutaneous Systemic Sclerosis (NCT05098145) | Talaris Therapeutics Inc. | 2021-11-24 |
| Vorbipiprant (CR6086) / Balstilimab (AGEN2034) Combination in Stage IV Refractory pMMR - MSS CRC, and Other Metastatic GI Cancers (NCT05205330) | Rottapharm Biotech | 2021-11-23 |
| LYR-220 for Adult Subjects With Chronic Rhinosinusitis (BEACON Study) (NCT05035654) | Lyra Therapeutics | 2021-11-23 |
| Masitinib in Patients With Symptomatic Mild to Moderate COVID-19 (NCT05047783) | AB Science | 2021-11-23 |
| ANTIVIRAL TREATMENT OF CYTOMEGALOVIRUS IN DEPRESSION (NCT04724447) | Laureate Institute for Brain Research, Inc. | 2021-11-23 |
| Trial of Chidamide in Combination With Envafolimab in Patients With PD-1 Inhibitor Resistant Advanced NSCLC. (NCT05068427) | Chipscreen Biosciences, Ltd. | 2021-11-23 |
| Chronocort Versus Plenadren Replacement Therapy in Adults With Adrenal Insufficiency (NCT05222152) | Neurocrine UK Limited | 2021-11-23 |
| Phase II Study of Fruquintinib Combined With Sintilimab and TACE for Inoperable Primary Hepatocellular Carcinoma (NCT05971199) | Zhejiang Cancer Hospital | 2021-11-23 |
| Efficacy, Safety and Tolerability of Sulthiame in Patients With Obstructive Sleep Apnea (OSA) (NCT05236842) | Desitin Arzneimittel GmbH | 2021-11-23 |
| Phase II Study of AVX/COVID-12 Vaccine in Subjects With Prior SARS-CoV-2 Immunity Evidence (NCT05205746) | Laboratorio Avi-Mex, S.A. de C.V. | 2021-11-23 |
| Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor (NCT05146440) | Grupo Espanol de Investigacion en Sarcomas | 2021-11-23 |
| Catumaxomab in Patients With Non-Muscle-Invasive Bladder Cancer Who Have Failed or Are Intolerant to BCG Vaccine (NCT04799847) | LintonPharm Co.,Ltd. | 2021-11-23 |
| Ketamine for the Treatment of Depression in Parkinson's Disease (NCT04944017) | Yale University | 2021-11-23 |
| Phase 2a Study of HPG1860 in Subjects With NASH (NCT05338034) | Hepagene (Shanghai) Co., Ltd. | 2021-11-22 |
| Molecular Profiling and Matched Targeted Therapy for Patients With Unresectable Advanced or Metastatic Melanoma (NCT02645149) | Melanoma Institute Australia | 2021-11-22 |
| Study of Intravaginal Tamoxifen in PostMenopausal Women With VVA (NCT05378269) | Daré Bioscience, Inc. | 2021-11-22 |
| Efficacy and Safety of AJU-S56 in Dry Eye Syndrome Patients (NCT06337981) | AJU Pharm Co., Ltd. | 2021-11-22 |
| Evaluation of Safety, Tolerability, and Efficacy of INZ-701 in Adults With ENPP1 Deficiency (NCT04686175) | Inozyme Pharma | 2021-11-21 |
| Camrelizumab Combined With Apatinib in the Treatment of Advanced Sarcomatoid Carcinoma or Carcinosarcoma (NCT05265793) | Fudan University | 2021-11-21 |
| Fruquintinib in the Treatment of Soft Tissue Sarcoma (NCT05142631) | Fudan University | 2021-11-21 |
| Efficacy, Safety, and Pharmacokinetics of ES-481 in Adult Patients With Essential Tremors (NCT05234762) | ES Therapeutics Australia Pty Ltd | 2021-11-21 |
| JMT101 Combined With Osimertinib in Patients With Stage Ⅲb-Ⅳ Non-small Cell Lung Cancer (NSCLC) Characterized by Epithermal Growth Factor Receptor (EGFR) Common Mutations (NCT06391944) | Shanghai JMT-Bio Inc. | 2021-11-21 |
| The Contribution of Platelet-Rich Plasma to the Surgical Treatment of Rotator Cuff Tear: An Experimental Study (NCT07689383) | KAT General Hospital | 2021-11-20 |
| Efficacy and Safety of JMT101 Combined With Osimertinib in Patients With Non-Small Cell Lung Cancer (NCT05132777) | Shanghai JMT-Bio Inc. | 2021-11-20 |
| Efficacy and Safety of Combinition of Camrelizumab in Second-line Neoadjuvant Chemotherapy and Adjuvant Therapy (NCT04848454) | Peking University First Hospital | 2021-11-20 |
| Impact of the Combined Treatment of Liposomed Polyphenols With G04CB02 on the ALS Patients (NCT04654689) | Fundación Universidad Católica de Valencia San Vicente Mártir | 2021-11-20 |
| Effect of Melatonin on Palatal Wound Healing (Randomized Controlled Clinical Trial) (NCT05122130) | Salma Nabil | 2021-11-20 |
| Efficacy, Safety and Immunological Evaluation of Tofacitinib in the Treatment of Primary Sjogren's Syndrome (NCT05087589) | Peking University People's Hospital | 2021-11-20 |
| Psilocybin for Treatment-Resistant Depression (NCT05029466) | Brain and Cognition Discovery Foundation | 2021-11-19 |
| Neostigmine and Glycopyrrolate for the Treatment of Headache After Dural Puncture (NCT05116930) | Mayo Clinic | 2021-11-19 |
| Ravulizumab Versus Placebo in Adult Participants With Dermatomyositis (NCT04999020) | Alexion Pharmaceuticals, Inc. | 2021-11-19 |
| Study to Assess AFM24 in Combination With Atezolizumab in Selected Advanced/Metastatic EGFR-expressing Cancers (NCT05109442) | Affimed GmbH | 2021-11-19 |
| An Open-label Safety Study of PC945 (Opelconazole) Prophylaxis or Pre-emptive Therapy Against Pulmonary Aspergillosis in Lung Transplant Recipients (OPERA-S Study) (NCT05037851) | Pulmocide Ltd | 2021-11-19 |
| An Investigator-Initiated, Phase II, Multicenter, Open-Label, Single-Arm, Prospective Clinical Trial to Evaluate the Efficacy and Safety of Alternating Bortezomib-Based Regimens in Combination With DaratUMumab Followed by Maintenance With Daratumumab in the Frontline Setting of Primary Plasma CEll L (NCT06636552) | Hellenic Society of Hematology | 2021-11-19 |
| Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease (NCT04713982) | Vanderbilt University Medical Center | 2021-11-19 |
| Cognitive Effects of Roflumilast in (a)MCI and Mild Dementia Patients (NCT04658654) | Maastricht University Medical Center | 2021-11-19 |
| A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery (NCT05130801) | Memorial Sloan Kettering Cancer Center | 2021-11-19 |
| Reduction of Peritoneal Glucose Uptake With Use of SGLT2 in Humans Undergoing Peritoneal Dialysis Treatment (NCT05250752) | Holbaek Sygehus | 2021-11-18 |
| Safety, Tolerability, and Immunogenicity of MenABCWY Administered on Different Dosing Schedules in Healthy Adolescents (NCT05087056) | GlaxoSmithKline | 2021-11-18 |
| Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial (NCT03990896) | Massachusetts General Hospital | 2021-11-18 |
| Nivolumab and Ipilimumab Plus Chemotherapy for Patients With Stage IV Lung Cancer With Brain Metastases (NCT05012254) | Fundación GECP | 2021-11-18 |
| Neurotransmitters in Treatment Resistant Schizophrenia Patients With add-on Sodium Benzoate (NCT06340789) | National Cheng-Kung University Hospital | 2021-11-18 |
| Study to Assess Efficacy and Safety of VIT-2763 (Vamifeport) in Subjects With Sickle Cell Disease (NCT04817670) | Vifor (International) Inc. | 2021-11-18 |
| A Study to Evaluate Safety and Tolerability of Olipudase Alfa in Pediatric and Adult Participants With Acid Sphingomyelinase Deficiency (ASMD) Who Completed the DFI12712 or the LTS13632 Study in France (NCT06949358) | Sanofi | 2021-11-18 |
| Evaluation of IBI302 Injection in nAMD or DME (NCT05961007) | Innovent Biologics (Suzhou) Co. Ltd. | 2021-11-18 |
| Personalized Selinexor-based Therapy for Relapsed/Refractory Multiple Myeloma (NCT04925193) | University of Colorado, Denver | 2021-11-18 |
| A Trial to Evaluate the Efficacy and Safety of Different Doses of KVD824 for Prophylactic Treatment of HAE Type I or II (NCT05055258) | KalVista Pharmaceuticals, Ltd. | 2021-11-18 |
| SurVaxM Plus Adjuvant Temozolomide for Newly Diagnosed Glioblastoma (SURVIVE) (NCT05163080) | MimiVax, LLC | 2021-11-18 |
| Pemetrexed and Carboplatin With or Without Anlotinib Hydrochloride for Osimertinib-resistant Non-squamous NSCLC (NCT04136535) | Fudan University | 2021-11-18 |