| CD8+ T Cell Imaging During Pre-surgery Immunotherapy in People With Melanoma (NCT05289193) | Memorial Sloan Kettering Cancer Center | 2022-03-11 |
| Nu-3 Topical Gel for Treatment of Diabetic Foot Ulcer (NCT05276401) | Lakewood-Amedex Inc | 2022-03-11 |
| GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC (NCT04864054) | Eureka Therapeutics Inc. | 2022-03-11 |
| Fruquintinib Combined With TAS-102 in the Treatment of Patients With Advanced Metastatic CRC (NCT05004831) | Sun Yat-sen University | 2022-03-11 |
| Allogenic Hepatocyte Transplantation Into Periduodenal Lymph Nodes (NCT04496479) | LyGenesis, Inc. | 2022-03-11 |
| Panitumumab and Pembrolizumab in Combination With Neoadjuvant Chemotherapy for the Treatment of Stage III-IV Triple Negative Breast Cancer (NCT05177796) | M.D. Anderson Cancer Center | 2022-03-11 |
| Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma (NCT04729959) | National Cancer Institute (NCI) | 2022-03-11 |
| TQ-B3525 Tablets Combined With Osimertinib Mesylate Tablets in the Treatment of Advanced Non-Small Cell Lung Cancer (NCT05284994) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2022-03-11 |
| Preop fSRS for Resectable Brain Metastases (NCT05267587) | H. Lee Moffitt Cancer Center and Research Institute | 2022-03-11 |
| Phase 2 Pilot Study of the Safety and Efficacy of Topical MW-III in Thermal Burns (NCT01297400) | Skingenix, Inc. | 2022-03-11 |
| Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer (NCT05247268) | Fudan University | 2022-03-11 |
| A Study of Trastuzumab and Pyrotinib in HER2 Positive Locally Advanced or Metastatic Urothelial Carcinoma (NCT05318339) | Chinese Academy of Medical Sciences | 2022-03-10 |
| IN10018 Combination Therapy in Previously-treated Locally Advanced or Metastatic Solid Tumor Patients (NCT05830539) | InxMed (Shanghai) Co., Ltd. | 2022-03-10 |
| An Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of Subjects With Batten Ceroid Lipofuscinosis, Neuronal 3 (CLN3) Disease (NCT05174039) | Beyond Batten Disease Foundation | 2022-03-10 |
| Evaluation of Safety and Efficacy of RZL-012 in Subjects Seeking Fat Reduction in the Flanks (NCT05445557) | Raziel Therapeutics Ltd. | 2022-03-10 |
| Thalidomide Combined With Chemotherapy and Monotherapy for Maintenance Treatment for Her2-negative Advanced GC (NCT05198856) | Qilu Hospital of Shandong University | 2022-03-10 |
| A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab As Monotherapy or Combined With Standard of Care Therapies in Adult Participants in China With B-Cell Non-Hodgkin Lymphoma (NCT05201248) | Genmab | 2022-03-10 |
| Study of ORIC-114 in Patients With Advanced Solid Tumors Harboring an EGFR or HER2 Alteration (NCT05315700) | ORIC Pharmaceuticals | 2022-03-10 |
| A Study of the Efficacy and Safety of Enclitide Chloride (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-008) (NCT05261126) | Merck Sharp & Dohme LLC | 2022-03-10 |
| High-Dose Moderna mRNA-1273 Booster Study for Lung Transplant Recipients (NCT05280158) | University of California, Los Angeles | 2022-03-10 |
| Efficiency of Tadalafil for Management of Female Sexual Dysfunction (NCT05266651) | Kasr El Aini Hospital | 2022-03-10 |
| The Efficacy and Safety of Neoadjuvant Low-dose Radiotherapy Combined With Chemoimmunotherapy in Locally Advanced HNSCC (NCT05343325) | Fifth Affiliated Hospital, Sun Yat-Sen University | 2022-03-09 |
| Irinotecan Plus Anlotinib or Further in Combination With Penpulimab for Second-line Treatment of mCRC (NCT05229003) | Fudan University | 2022-03-09 |
| Ambroxol as a Disease-modifying Treatment in GBA-PD (NCT05287503) | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 2022-03-09 |
| A Study to Evaluate the Activity, Safety and Tolerability of ZX-101A in Advanced Solid Tumors (NCT05258266) | Nanjing Zenshine Pharmaceuticals | 2022-03-09 |
| COvid-19 Vaccine Booster in Immunocompromised Rheumatic Diseases (NCT05236491) | Paul R Fortin | 2022-03-09 |
| Study to Evaluate the Effect of Obicetrapib in Combination With Ezetimibe as an Adjunct to HIS Therapy (NCT05266586) | NewAmsterdam Pharma | 2022-03-09 |
| DOAC Versus VKA After Cardiac Surgery (NCT04002011) | Laval University | 2022-03-09 |
| Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (NCT05280470) | Daiichi Sankyo | 2022-03-09 |
| Addressing Quality of Life, Clinical Outcomes, and Mechanisms in Uncontrolled Asthma Following the DASH Dietary Pattern (NCT05251402) | University of Illinois at Chicago | 2022-03-09 |
| A Study Evaluating the Safety and Efficacy of GLPG5101 (19CP02) in Participants With Non-Hodgkin Lymphoma (NCT06561425) | Lakefront Biotherapeutics NV | 2022-03-09 |
| Incentives for Oklahoma Tobacco Helpline Engagement in Persistent Poverty Counties (NCT05095779) | University of Oklahoma | 2022-03-09 |
| Safety, PK and Efficacy of PCS12852 on Gastric Emptying Rate in Patients With Moderate to Severe Gastroparesis (NCT05270460) | Processa Pharmaceuticals | 2022-03-09 |
| Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases (NCT04711824) | Colette Shen | 2022-03-09 |
| Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice Care (NCT04950608) | Yvan Beaussant, MD, MSci | 2022-03-09 |
| A Trial of Intratumoural Tigilanol Tiglate in Adult Participants With Stage IIIB to IV M1c Melanoma (NCT05234437) | QBiotics Group Limited | 2022-03-09 |
| A Clinical Trial to Evaluate the Safety and Efficacy of Rreproxalap in Adults With Dry Eye Disease (NCT05424549) | Aldeyra Therapeutics, Inc. | 2022-03-09 |
| BEMPEG With Pembrolizumab vs Pembrolizumab Alone in Patients With Metastatic or Recurrent HNSCC (PROPEL-36) (NCT04969861) | Nektar Therapeutics | 2022-03-09 |
| A Study Evaluating the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Occlusive Episodes (VOE) in Sickle Cell Disease (SCD) (NCT05075824) | Hoffmann-La Roche | 2022-03-09 |
| Safety, Tolerability and Immunogenicity of Gam-COVID-Vac Vaccine in a Nasal Spray (NCT05248373) | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 2022-03-08 |
| CCMR Two: A Phase IIa, Randomised, Double-blind, Placebo-controlled Trial of the Ability of the Combination of Metformin and Clemastine to Promote Remyelination in People With Relapsing-remitting Multiple Sclerosis Already on Disease-modifying Therapy (NCT05131828) | Cambridge University Hospitals NHS Foundation Trust | 2022-03-08 |
| An Extension Study to Evaluate the Long-Term Safety and Clinical Activity of mRNA-3705 in Participants Previously Enrolled in Other Clinical Studies of mRNA-3705 (NCT05295433) | ModernaTX, Inc. | 2022-03-08 |
| Phase 1/2a Study of MPB-1734 in Patients With Advanced Solid Tumors (NCT04643418) | MegaPro Biomedical Co. Ltd. | 2022-03-08 |
| Clinical Study to Investigate the Safety, Tolerability, and Pharmacokinetics of GR1603 in SLE (NCT06015230) | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 2022-03-08 |
| Reducing Pain and Opioid Use With CBD (NCT05299944) | University of Colorado, Denver | 2022-03-08 |
| Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus (NCT05314738) | Glaukos Corporation | 2022-03-08 |
| Efficacy of Talazoparib in Asian Metastatic Breast Cancer Patients With a Homologous Recombinant Deficiency (HRD) Signature (NCT05288127) | University of Malaya | 2022-03-08 |
| Accelerated Dose Schedule of Cytarabine Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML) in Complete Remission (NCT04914676) | University of Florida | 2022-03-08 |
| Pilot Decentralized Clinical Trial in Men and Pre and Post-menopausal Women With Breast Cancer and a Specific Mutation (PIK3CA) Treated With Alpelisib in Combination With Fulvestrant (NCT04862143) | Novartis Pharmaceuticals | 2022-03-08 |
| Efficacy and Safety of Sorafenib in Previously Treated Advanced Hepatocellular Carcinoma: SOPT Study (NCT05117957) | Bo Hyun Kim | 2022-03-08 |
| Clinical Study of VG161 in Combination With Nivolumab in Subjects With Advanced Pancreatic Cancer (NCT05162118) | Zhejiang University | 2022-03-08 |
| Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma in African-American and European-American Patients (NCT05014646) | City of Hope Medical Center | 2022-03-07 |
| A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B) (NCT05277571) | UCB Biopharma SRL | 2022-03-07 |
| A IMMA Master Protocol: A Study of LY3361237 in Participants With at Least Moderately Active Systemic Lupus Erythematosus (NCT05123586) | Eli Lilly and Company | 2022-03-07 |
| AGuIX Nanoparticles With Radiotherapy Plus Concomitant Temozolomide in the Treatment of Newly Diagnosed Glioblastoma (NCT04881032) | Centre Jean Perrin | 2022-03-07 |
| To Evaluate Efficacy, Safety, Tolerability and PK of Intravenous Cipargamin in Participants With Severe Plasmodium Falciparum Malaria (NCT04675931) | Novartis Pharmaceuticals | 2022-03-07 |
| A Study to Evaluate the Cardiac Safety of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Advanced Malignant Tumor (NCT05089461) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2022-03-07 |
| Clinical Study on the Efficacy and Safety of Multiple Oral Administrations of SHR2285 Tablets in Patients Undergoing Elective Total Knee Arthroplasty (NCT05203705) | Shanghai Hengrui Pharmaceutical Co., Ltd. | 2022-03-07 |
| A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital Herpes (NCT05298254) | GlaxoSmithKline | 2022-03-07 |
| Tarlox and Sotorasib in Patients With KRAS G12C Mutations (NCT05313009) | Medical University of South Carolina | 2022-03-07 |
| Pilot Study on BP1.4979 Effect on Binge Eating Disorders (NCT05118906) | Bioprojet | 2022-03-07 |
| Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP) (NCT04896073) | National Cancer Institute (NCI) | 2022-03-07 |
| Photoallergic Potential of 6% Bemotrizinol (NCT05254912) | dsm-firmenich Switzerland AG | 2022-03-07 |
| Safety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastatic Castrate Resistant Prostate Cancer (NCT05081193) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2022-03-07 |
| Use of Aromatherapy to Reduce Symptom Burden (NCT05251337) | Indiana University | 2022-03-07 |
| Corticosteroids to Treat Pancreatitis (NCT05160506) | Beth Israel Deaconess Medical Center | 2022-03-06 |
| Identify Effective Doses of SHR7280 Tablets in Controlled Ovarian Hyperstimulation (COH) for Female Subjects Undergoing Assisted Reproductive Technology (ART) (NCT05082233) | Jiangsu HengRui Medicine Co., Ltd. | 2022-03-06 |
| How Does Platelet Dose Impact Clinical Outcomes After PRP Treatment? (NCT05330689) | Vanderbilt University Medical Center | 2022-03-06 |
| Study to Evaluate the Efficacy and Safety of EG-009A Compared to DEX in Patients With COVID-19 Pneumonia (NCT04561180) | Evergreen Therapeutics, Inc. | 2022-03-04 |
| Study of Envafolimab Alone or With Lenvatinib in Patients With Advanced Endometrial Cancer (NCT05112991) | 3D Medicines (Sichuan) Co., Ltd. | 2022-03-04 |
| Pharmacokinetic Study for IV Allopregnanolone (NCT04468360) | Boston University | 2022-03-04 |
| Safety, Efficacy and Pharmacokinetics of CBT-008 in Patients With Meibomian Gland Dysfunction (NCT05261386) | Cloudbreak Therapeutics, LLC | 2022-03-04 |
| Cardioprotection in AML (NCT04977180) | University of Virginia | 2022-03-04 |
| Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (NCT04930744) | University of Massachusetts, Worcester | 2022-03-04 |
| A Study of Docetaxel for Injection (Albumin-bound) in Combination With Nivolumab in Patients With Head and Neck (SCCHN) (NCT05027204) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2022-03-04 |
| An Exploratory Basket Study of Pyrotinib Maleate Tablets in HER2 Mutated or Amplified of Metastatic Solid Tumors (NCT05274191) | Zhongshan Hospital Xiamen University | 2022-03-04 |
| Phase I/II Study of Tagraxofusp in Combination With Decitabine for Patients With Myelomonocytic/Myeloproliferative Neoplasm and High Risk Myelodysplastic Syndromes (NCT05038592) | M.D. Anderson Cancer Center | 2022-03-04 |
| Neuroimaging Study of Dexmedetomidine-Induced Analgesia (NCT04656470) | Massachusetts General Hospital | 2022-03-04 |
| Evaluating Efficacy of Tivozanib (AV-951) in Biliary Tract Cancers (NCT04645160) | National Cancer Institute (NCI) | 2022-03-04 |
| A Study on Radiation Therapy Guided by the Reflectance Confocal Microscopy (RCM)/Optical Coherence Tomography (OCT) Device in People With Basal Cell Carcinoma (NCT05294120) | Memorial Sloan Kettering Cancer Center | 2022-03-03 |
| Lurbinectedin Monotherapy in Participants With Advanced or Metastatic Solid Tumors (NCT05126433) | Jazz Pharmaceuticals | 2022-03-03 |
| Effects of Psilocybin on Electrophysiology and the Dynamic Content of Thought (NCT05301608) | Johns Hopkins University | 2022-03-03 |
| FRDA Investigator Initiated Study (IIS) With Elamipretide (NCT05168774) | Children's Hospital of Philadelphia | 2022-03-03 |
| PHE885 CAR-T Therapy in Adult Participants With Relapsed and Refractory Multiple Myeloma (NCT05172596) | Novartis Pharmaceuticals | 2022-03-03 |
| Phase 2 Study to Assess the Safety, PK, and PD of Sonefpeglutide (HM15912) in SBS-IF Subjects (NCT04775706) | Hanmi Pharmaceutical Company Limited | 2022-03-03 |
| COAST Therapy in Advanced Solid Tumors and Prostate Cancer (NCT05036226) | Medical University of South Carolina | 2022-03-03 |
| Study to Investigate Alternative Dosing Regimens of Belantamab Mafodotin in Participants With Relapsed or Refractory Multiple Myeloma (NCT05064358) | GlaxoSmithKline | 2022-03-03 |
| Study to Investigate LP352 in Subjects With Developmental and Epileptic Encephalopathies (NCT05364021) | Longboard Pharmaceuticals | 2022-03-03 |
| Basimglurant (NOE-101) in Children, Adolescents, and Young Adults With TSC (NCT05059327) | Noema Pharma AG | 2022-03-03 |
| A Study of RC118 in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors (NCT05205850) | RemeGen Co., Ltd. | 2022-03-03 |
| Rituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop Study (NCT04978584) | M.D. Anderson Cancer Center | 2022-03-03 |
| Trilaciclib, a CDK4/6 Inhibitor, in Patients With Early-Stage Triple Negative Breast Cancer (NCT05112536) | G1 Therapeutics, Inc. | 2022-03-03 |
| Low Dose Vemurafenib and Rituximab in Hairy Cell Leukemia (NCT05388123) | Scripps Health | 2022-03-02 |
| Neoadjuvant Immunotherapy Plus CRT Versus Neoadjuvant CRT for Locally Advanced Resectable ESCC (NCT04973306) | Shanghai Zhongshan Hospital | 2022-03-02 |
| Pressure Enabled Delivery of SD-101 With Checkpoint Blockade for Primary Liver Tumors (NCT05220722) | TriSalus Life Sciences, Inc. | 2022-03-02 |
| Pharmacologic Pretransplant Immunosuppression (PTIS) + Reduced Toxicity Conditioning (RTC) Allogeneic Stem Cell Transplantation in Inherited Hematologic Disorders (NCT05293509) | M.D. Anderson Cancer Center | 2022-03-02 |
| Adjuvant Durvalumab Plus Regorafenib vs Untreated Control in Stage IV Colorectal Cancer Patients With no Evidence of Disease (NED): VIVA Trial (NCT05382741) | Ospedale Policlinico San Martino | 2022-03-02 |
| Low-dose Radiotherapy Combined With Durvalumab, Chemotherapy(EP) in the Treatment of ES-SCLC (NCT05092412) | You Lu | 2022-03-02 |
| Phase 1/2 Study of HS-10375 in Patients with Advanced or Metastatic Non-Small-Cell Lung Cancer(NSCLC) (NCT05435248) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2022-03-02 |
| Safety, Tolerability, and Efficacy Study of UBX1325 in Patients With Neovascular Age-Related Macular Degeneration (ENVISION) (NCT05275205) | Unity Biotechnology, Inc. | 2022-03-02 |