| Efficacy and Safety of RMC-035 in Subjects at High Risk for Acute Kidney Injury Following Open-Chest Cardiac Surgery (NCT05126303) | Guard Therapeutics AB | 2022-03-31 |
| Brightline-1: A Study to Compare Brigimadlin (BI 907828) With Doxorubicin in People With a Type of Cancer Called Dedifferentiated Liposarcoma (NCT05218499) | Boehringer Ingelheim | 2022-03-31 |
| Effect of Oral Microbiota on MDRO Decolonization (NCT07496502) | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | 2022-03-31 |
| Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors (NCT05269381) | Mayo Clinic | 2022-03-31 |
| A Phase II Study of Neoadjuvant Sotorasib in Combination With Cisplatin or Carboplatin and Pemetrexed for Surgically Resectable Stage IIA-IIIB Non-Squamous Non-Small Cell Lung Cancer With a KRAS p.G12C Mutation (NCT05118854) | M.D. Anderson Cancer Center | 2022-03-30 |
| A Trial of Early Detection of Molecular Relapse With Circulating Tumour DNA Tracking and Treatment With Palbociclib Plus Fulvestrant Versus Standard Endocrine Therapy in Patients With ER Positive HER2 Negative Breast Cancer (NCT04985266) | Royal Marsden NHS Foundation Trust | 2022-03-30 |
| Study to Assess the Safety, Tolerability of JPI-547 in Combination With Modified FOLFIRINOX or Gemcitabine-nab-paclitaxel in Patients With Locally Advanced and Metastatic Pancreatic Cancer (NCT05257993) | Onconic Therapeutics Inc. | 2022-03-30 |
| Evaluating the Safety and Efficacy of a Novel Accelerated Partial Breast Irradiation Regimen (NCT05591547) | Sanford Health | 2022-03-30 |
| The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis (NCT04372615) | University of Utah | 2022-03-30 |
| A Phase II Clinical Study of Fruquintinib Combined With S-1 for Advanced Esophageal Squamous Cell Carcinoma (NCT05636150) | Peking Union Medical College Hospital | 2022-03-30 |
| Study to Demonstrate Safety and Duration of Effect of 40 Units of PrabotulinumtoxinA-xvfs to Treat Glabellar Lines (NCT05320393) | Evolus, Inc. | 2022-03-30 |
| Surufatinib With or Wothout Immunotherapy for Advanced Colorectal Cancer in Later Line (NCT05372198) | Hubei Cancer Hospital | 2022-03-30 |
| Personalized Neoantigen Vaccine in Combination With Durvalumab (MEDI4736) in Extensive Stage Small Cell Lung Cancer (NCT04397003) | Washington University School of Medicine | 2022-03-30 |
| Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease (NCT05312879) | Vertex Pharmaceuticals Incorporated | 2022-03-30 |
| Study of Camrelizumab in Combination With Apatinib Mesylate Plus Albumin-bound Paclitaxel and Cisplatin as the First Line Treatment of Recurrent or Metastatic, UnresectableHead and Neck Squamous Cell Carcinoma (NCT05189184) | The First Affiliated Hospital of Zhengzhou University | 2022-03-30 |
| Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis (NCT04380740) | Boston Children's Hospital | 2022-03-30 |
| Study of Chidamide, Decitabine and Immune Checkpoint Inhibitors in R/R NHL and Advanced Solid Tumors (NCT05320640) | Chinese PLA General Hospital | 2022-03-30 |
| Suvorexant as an Adjunct to Buprenorphine in Persons Who Use Fentanyl (NCT05145764) | Johns Hopkins University | 2022-03-30 |
| COVID-19 Variant Immunologic Landscape Trial (COVAIL Trial) (NCT05289037) | National Institute of Allergy and Infectious Diseases (NIAID) | 2022-03-30 |
| Dose-ranging, PK, Safety, Efficacy Study of Osanetant in Patients With Moderate/Severe VMS Associated With Menopause (NCT05325775) | Acer Therapeutics Inc. | 2022-03-30 |
| A Study of HYML-122 and Cytarabine in Patients With FLT3 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML) (NCT05241093) | Tarapeutics Science Inc. | 2022-03-29 |
| A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome (NCT05163808) | Tetra Discovery Partners | 2022-03-29 |
| 4D-710 in Adult Patients With Cystic Fibrosis (NCT05248230) | 4D Molecular Therapeutics | 2022-03-29 |
| A Study of Treprostinil Palmitil Inhalation Powder (TPIP) In Pulmonary Arterial Hypertension (PAH) (NCT04791514) | Insmed Incorporated | 2022-03-29 |
| Cabozantinib and Atezolizumab for the Treatment of Metastatic Castration-Resistant Prostate Cancer (NCT05168618) | University of Utah | 2022-03-29 |
| A Study of Oral GLP1RA RGT001-075 in Adults With Type 2 Diabetes (NCT05297045) | Regor Pharmaceuticals Inc. | 2022-03-29 |
| Assess Fibrin in Brains With AD/ADRD (NCT05336695) | Massachusetts General Hospital | 2022-03-29 |
| Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (MK-7240-007) (NCT05270668) | Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2022-03-29 |
| REACH: Study to Determine the Aetiology of Chlormethine Gel Induced-skin Drug Reaction in Early Stage Mycosis Fungoides Cutaneous T Cell Lymphoma (MF-CTCL) (NCT04218825) | European Organisation for Research and Treatment of Cancer - EORTC | 2022-03-29 |
| Study of BOTOX Injections to Assess Change in Disease Activity and Adverse Events in Adult Female Participants With Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) (NCT05141006) | AbbVie | 2022-03-29 |
| Study of Combination Therapy of D07001-Softgel Capsules and Xeloda/TS-1 in Subjects With Advanced Biliary Tract Cancer (NCT05065957) | InnoPharmax Inc. | 2022-03-29 |
| The Safety and Efficacy of Psilocybin in Patients With Treatment-resistant Depression and Chronic Suicidal Ideation (NCT05220410) | Sheppard Pratt Health System | 2022-03-28 |
| Efficacy of Cilostazol in Prevention of Peripheral Neuropathy (NCT05298696) | Mansoura University | 2022-03-28 |
| Transplantation of Hematopoietic Stem Cells From HLA-compatible Donors in Patients With B-Cell Lymphoid Malignancies (NCT04684979) | Baptist Health South Florida | 2022-03-28 |
| A Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease (NCT04987489) | Forma Therapeutics, Inc. | 2022-03-28 |
| Evaluation of Treatment Predictors Reflecting Beta-catenin Activation in Hepatocellular Carcinoma (NCT04965454) | Queen's Medical Center | 2022-03-28 |
| Cabozantinib in Combination With Avelumab in Patients Refractory to Standard Chemotherapy With Advanced Neuroendocrine Neoplasias G3 (NEN G3) (NCT05289856) | Johannes Gutenberg University Mainz | 2022-03-28 |
| Radiotherapy Combined With PD-1 Monoclonal Antibody and Capecitabine in the Treatment of Nasopharyngeal Carcinoma (NCT05290194) | Fifth Affiliated Hospital, Sun Yat-Sen University | 2022-03-28 |
| 64Cu-SAR-bisPSMA Positron Emission Tomography of Patients With Known or Suspected Prostate Cancer (NCT05286840) | Luke Nordquist, MD | 2022-03-28 |
| Using ctDNA to Determine Therapies for Lung Cancer (NCT04966663) | University Health Network, Toronto | 2022-03-28 |
| Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL) (NCT04895436) | AbbVie | 2022-03-28 |
| Phase 2 of HU-045 in Glabellar Lines (NCT05298449) | Huons Co., Ltd. | 2022-03-28 |
| A Study to Evaluate the Safety and Efficacy of Afamelanotide in Patients With Xeroderma Pigmentosum C and V (NCT05370235) | Clinuvel Europe Limited | 2022-03-28 |
| The Effect of Voxelotor on Cerebral Hemodynamic Response in Children With Sickle Cell Anemia (NCT05018728) | Emory University | 2022-03-28 |
| Randomised Trial of Induction Gemcitabine and Cisplatin Versus Gemcitabine, Cisplatin, Pembrolizumab and Bevacizumab (GPPB) in Nasopharyngeal Cancer (NCT05305131) | National University Hospital, Singapore | 2022-03-28 |
| Niraparib Plus Anlotinib for Recurrent Ovarian Cancer (NCT05311579) | Lei Li | 2022-03-27 |
| Albumin-bound Paclitaxel and Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (NCT05310344) | Lei Li | 2022-03-27 |
| Tislelizumab and Radiotherapy for Recurrent Cervical Cancer (NCT05310383) | Lei Li | 2022-03-27 |
| PD-1 Antibody Plus Chemoradiotherapy for IB2-IIIB Cervical Cancer (NCT05311566) | Lei Li | 2022-03-27 |
| Donafenib for Recurrent Cervical Cancer (NCT05310331) | Lei Li | 2022-03-27 |
| Prophylaxis of Cytomegalovirus Infection With Adoptive Cell Inmunotherapy (NCT04056533) | Instituto de Investigación Marqués de Valdecilla | 2022-03-26 |
| Safety and Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Multiple Sclerosis (NCT05168384) | Abu Dhabi Stem Cells Center | 2022-03-26 |
| Assessment on Effects of Tongjiang Granule in Treating Nonerosive Reflux Disease Overlapping Epigastric Pain Syndrome (NCT05312463) | Xiyuan Hospital of China Academy of Chinese Medical Sciences | 2022-03-26 |
| Chlorophyllin Tablets for Urinary Bleeding Following Radiation Therapy for Cancers of Pelvic Organs (NCT05348239) | Tata Memorial Centre | 2022-03-26 |
| A Study to Evaluate BMS-986141 Added on to Aspirin or Ticagrelor or the Combination, on Thrombus Formation in a Thrombosis Chamber Model in Participants With Stable Coronary Artery Disease and Healthy Participants (NCT05093790) | Bristol-Myers Squibb | 2022-03-25 |
| Predicting Olaparib Sensitivity in Patients With Unresectable Locally Advanced/Metastatic HER2-negative Breast Cancer. (NCT05340413) | SOLTI Breast Cancer Research Group | 2022-03-25 |
| First-line Treatment of P53 Mutation With PD-L1 Expression in DLBCL With Anti-PD-1 Mab and R-CHOP (NCT05280626) | Innovent Biologics (Suzhou) Co. Ltd. | 2022-03-25 |
| A Study on the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of CAN106 in Subjects With PNH (NCT05539248) | CARE Pharma Shanghai Ltd. | 2022-03-25 |
| A Study in Patients With Advanced Cancers (NCT05320588) | BiOneCure Therapeutics Inc. | 2022-03-25 |
| Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype (NCT05269628) | Tiffany J. Braley, MD, MS | 2022-03-25 |
| A Trial to Evaluate the Effects of BCG in Adults With MCI and Mild-to-Moderate AD (NCT05004688) | Steven E Arnold, MD | 2022-03-25 |
| Assessing the Immunogenicity and Safety of a HIPRA's Candidate Booster Vaccination in Adults Fully Vaccinated With Adenovirus Vaccine Against COVID-19. (NCT05305573) | Hipra Scientific, S.L.U | 2022-03-25 |
| Evaluate the Efficacy and Safety of SPC1001 and Monotherapy in Patients With Essential Hypertension (NCT06212648) | Shin Poong Pharmaceutical Co. Ltd. | 2022-03-25 |
| A Study to Evaluate the Efficacy and Safety of Ivermectin in COVID-19 Prevention (NCT05305560) | MedinCell S.A | 2022-03-25 |
| DURvalumab in Combination With S-488210/S-488211 vAccine in Non-muscle Invasive Bladder CancEr (NCT04106115) | University College, London | 2022-03-25 |
| Decatecholaminisation of Septic Shock With Dexmedetomidine and In-hospital Mortality (NCT05283083) | Mansoura University | 2022-03-25 |
| Radiotherapy in Combination With Sintilimab，GM-CSF and Fruquintinib in Patients With MSS mCRC (NCT05292417) | The First Affiliated Hospital of Xiamen University | 2022-03-25 |
| A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC) (NCT05307939) | Memorial Sloan Kettering Cancer Center | 2022-03-24 |
| Donor Regulatory T-cells for cGVHD in Patients Who do Not Obtain Complete Remission With Ruxolitinib (NCT05095649) | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 2022-03-24 |
| Study of Posoleucel (ALVR105,Viralym-M) for Multi-Virus Prevention in Patients Post-Allogeneic Hematopoietic Cell Transplant (NCT05305040) | AlloVir | 2022-03-24 |
| Efficacy and Safety of ME3183 in Subjects With Moderate to Severe Plaque Psoriasis (NCT05268016) | Meiji Pharma USA Inc. | 2022-03-24 |
| Pembrolizumab and Olaparib in Recurrent/Metastatic, Platinum Resistant Nasopharyngeal Cancer (NCT04825990) | Gruppo Oncologico del Nord-Ovest | 2022-03-24 |
| Study of SQZ-eAPC-HPV in Patients With HPV16+ Recurrent, Locally Advanced or Metastatic Solid Tumors (NCT05357898) | SQZ Biotechnologies | 2022-03-24 |
| Phase II Study of Anti-CD19 CAR-T Cells Treating Leukemia Children (NCT04325841) | Beijing Boren Hospital | 2022-03-24 |
| The Safety and Efficacy of MoodElite T-4003-1 on Improving Mood in a Healthy Adult Population With Mild to Moderate Depressive Symptoms Not Eligible for Therapeutic Intervention (NCT05318456) | Chenland Nutritionals Inc. | 2022-03-24 |
| Evaluation of CPX-351 Monotherapy in Acute Myeloid Leukemia Secondary to Myeloproliferative Neoplasm (NCT04992949) | French Innovative Leukemia Organisation | 2022-03-23 |
| Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML (NCT05184842) | Montefiore Medical Center | 2022-03-23 |
| Sacituzumab Govitecan, Preceding Radical Cystectomy, in Treating Patients With Muscle-invasive Bladder Cancer (NCT05226117) | IRCCS San Raffaele | 2022-03-23 |
| Sphenopalatine Ganglion Block for the Treatment of Post-Stroke Headache (NCT05365880) | University of Utah | 2022-03-23 |
| Mosunetuzumab With or Without Polatuzumab Vedotin and Obinutuzumab for the Treatment of Untreated Indolent B-Cell Non-Hodgkin Lymphoma (NCT05169658) | University of Washington | 2022-03-23 |
| A Phase 2 Placebo Controlled, Clinical Trial Designed to Assess the Efficacy, Safety and Dose Response Characterisation of STS01 for the Treatment of Mild-moderate Alopecia Areata (AA) (NCT06402630) | Soterios Ltd | 2022-03-23 |
| A Study of MRG002 in Treatment of Advanced HER-2 Positive Breast Cancer Patients (NCT05263869) | Shanghai Miracogen Inc. | 2022-03-23 |
| HLX07+HLX10+Chemotherapy or HLX07 Monotherapy in Patients With Advanced Metastatic Gastric Cancer (NCT05246982) | Shanghai Henlius Biotech | 2022-03-23 |
| Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors (NCT05275478) | Tango Therapeutics, Inc. | 2022-03-23 |
| A Phase 2 Study of Neoadjuvant Docetaxel, Oxaliplatin, S-1 in Patients With Unresectable Locally Advanced or Distant Metastasis Limited to Lymph Node Gastric Cancer (NCT05184803) | Asan Medical Center | 2022-03-23 |
| The Efficacy and Safety of HLX208 in Metastatic Colorectal Cancer (mCRC) With BRAF V600E Mutation (NCT05127759) | Shanghai Henlius Biotech | 2022-03-23 |
| Trans Auricular Vagus Nerve Stimulation (taVNS) and Robotic Training for Paralyzed Arm After Stroke (NCT05339893) | Northwell Health | 2022-03-23 |
| A Study of AK117/AK112 in Metastatic Triple-Negative Breast Cancer (NCT05227664) | Akeso | 2022-03-23 |
| A Study on the Safety, Efficacy and Immune Response Following Sequential Treatment With an Anti-sense Oligonucleotide Against Chronic Hepatitis B (CHB) and Chronic Hepatitis B Targeted Immunotherapy (CHB-TI) in CHB Patients Receiving Nucleos(t)Ide Analogue (NA) Therapy (NCT05276297) | GlaxoSmithKline | 2022-03-22 |
| Combination of Capmatinib + Spartalizumab in Advanced Oesogastric Adenocarcinoma (NCT05135845) | Assistance Publique - Hôpitaux de Paris | 2022-03-22 |
| Study to Assess the Safety, Tolerability and Explore the Immunogenicity of EG-COVID and EG-COVARo in Healthy Adult Volunteers (NCT05188469) | EyeGene Inc. | 2022-03-22 |
| LiftActiv B3 in Post Inflammatory Hyperpigmentation (PIHP) (NCT05327361) | University of Miami | 2022-03-22 |
| Thal-Fabs: Reduced Toxicity Conditioning for High Risk Thalassemia (NCT05426252) | The Hospital for Sick Children | 2022-03-22 |
| Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma (NCT05001880) | National Cancer Institute (NCI) | 2022-03-22 |
| Evaluation of [18F]APN-1607 PET Uptake in Alzheimer's Disease Patients Compared With Healthy Subjects (NCT04141150) | APRINOIA Therapeutics, LLC | 2022-03-22 |
| Efficacy of Liraglutide Therapy in Patients With IPAA (NCT04763564) | University of North Carolina, Chapel Hill | 2022-03-22 |
| Tofacitinib for the Treatment of Refractory Immune-related Colitis from Checkpoint Inhibitor Therapy- TRICK Study (NCT04768504) | Khashayar Esfahani | 2022-03-22 |
| A Study to Evaluate the Safety and Efficacy of Glofitamab in Combination With Rituximab (R) Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (CHOP) in Circulating Tumor (ct)DNA High-Risk Patients With Untreated Diffuse Large B-Cell Lymphoma (NCT04980222) | Hoffmann-La Roche | 2022-03-22 |
| Zanubrutinib Followed Zanubrutinib Plus FCR / BR in Newly Diagnosed Symptomatic CLL/SLL (NCT05287984) | Institute of Hematology & Blood Diseases Hospital, China | 2022-03-22 |
| Efficacy and Safety of Iguratimod in the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia (NCT05302024) | Peking University People's Hospital | 2022-03-22 |