| Study of ARO-RAGE in Healthy Subjects and Patients With Inflammatory Lung Disease (NCT05276570) | Arrowhead Pharmaceuticals | 2022-06-29 |
| Functional Cure Study of Anti-PD-L1 Antibody ASC22 in Combination With Chidamide in HIV-infected Patients With Antiviral Suppression (NCT05129189) | Shanghai Public Health Clinical Center | 2022-06-29 |
| Placebo-controlled, Proof-of-concept Study to Evaluate the Safety and Efficacy of Lanifibranor Alone and in Combination With SGLT2 Inhibitor EmpaGliflozin in patiEnts With NASH and Type 2 Diabetes Mellitus (NCT05232071) | Inventiva Pharma | 2022-06-29 |
| A Phase Ib/II Study of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection in Chinese Participants With Acute Gout (NCT05588908) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2022-06-29 |
| Caffeine Kinetics and CrossFit®-Specific Performance (NCT05516212) | Poznan University of Physical Education | 2022-06-29 |
| A Study of TCD601 in the Induction of Tolerance in de Novo Liver Transplantation (NCT06019507) | ITB-Med LLC | 2022-06-29 |
| Copanlisib and Venetoclax for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma (NCT04939272) | City of Hope Medical Center | 2022-06-29 |
| Phase 1/2 Study Evaluating Safety and Potential Efficacy of Allocetra-OTS Via Pressurized Intra-Peritoneal Aerosol Chemotherapy as Add-on to Standard of Care Chemotherapy for Treatment of Peritoneal Metastasis (NCT05431907) | Enlivex Therapeutics RDO Ltd. | 2022-06-29 |
| A Biomarker-Guided, Randomized, Placebo-Controlled Efficacy and Safety Study of Liafensine in Patients With TRD (NCT05113771) | Denovo Biopharma LLC | 2022-06-29 |
| A Study of GZR18 Injection in Chinese Adult Patients With Type 2 Diabetes Mellitus (T2DM) (NCT06256523) | Gan and Lee Pharmaceuticals, USA | 2022-06-29 |
| A Dose Escalation and Expansion Study of TAC-001 in Patients With Select Advanced or Metastatic Solid Tumors (NCT05399654) | Tallac Therapeutics | 2022-06-28 |
| Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders (NCT05286294) | Oslo University Hospital | 2022-06-28 |
| Intraperitoneal Chemotherapy Guided by the Detection of DNA in Peritoneal Lavage Fluid in Patients With Gastric Cancer (NCT05497739) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2022-06-28 |
| A Study of CDX-0159 in Patients With Chronic Inducible Urticaria (NCT05405660) | Celldex Therapeutics | 2022-06-28 |
| Study to Evaluate Safety, Tolerance and Efficacy of ASC22 Combined With ART in Subjects With HIV (NCT05330143) | Ascletis Pharmaceuticals Co., Ltd. | 2022-06-28 |
| Angiotensin II in Liver Transplantation (NCT04901169) | University of California, San Francisco | 2022-06-28 |
| Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung (NCT05058651) | National Cancer Institute (NCI) | 2022-06-28 |
| A Phase 2a Study of TAS5315 in Patients With Chronic Spontaneous Urticaria (NCT05335499) | Taiho Pharmaceutical Co., Ltd. | 2022-06-28 |
| Oral Levonorgestrel Plus Meloxicam, IG-002 Delays Ovulation in Normal Menstruating Women by Seven Days (NCT05695352) | InnovaGyn, Inc. | 2022-06-28 |
| Hyperbaric Oxygen Effects on Persistent Post-concussive Symptoms (NCT05173818) | Essentia Health | 2022-06-28 |
| OA Optimization Program Pilot Trial (NCT05389371) | University of Calgary | 2022-06-28 |
| Ofatumumab in AQP4-IgG Seropositive NMOSD (NCT05504694) | Tang-Du Hospital | 2022-06-28 |
| MAGnesium Effect With ANtiosteoporotic Drugs (NCT05328154) | University Hospital, Clermont-Ferrand | 2022-06-28 |
| A Trial to Assess the Efficacy and Safety of Octreotide Subcutaneous Depot in Patients With PLD (NCT05281328) | Camurus AB | 2022-06-28 |
| A Study of SARS-CoV-2 mRNA Vaccine (SYS6006) in Chinese Healthy Participants Aged 18 Years or More (NCT05439824) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2022-06-28 |
| DUET Study: A Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Orally Administered TERN-501 as Monotherapy and in Combination With TERN-101 in Noncirrhotic Adults With Presumed Non-Alcoholic Steatohepatitis (NCT05415722) | Terns, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2022-06-28 |
| A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) (NCT05282121) | Boehringer Ingelheim | 2022-06-28 |
| Regorafenib Combined With Fulvestrant in Recurrent Low-Grade Serous Ovarian Cancer (NCT05113368) | Sarah K. Lynam MD | 2022-06-28 |
| Neoadjuvant Pembrolizumab in Cutaneous Squamous Cell Carcinoma (NCT05025813) | Queensland Health | 2022-06-28 |
| A Phase II Study of AK104 Plus Lenvatinib and TACE in HCC (NCT05319431) | Akeso | 2022-06-28 |
| Phase 2, Multi-center, Randomized, Double- Masked and Placebo-Controlled Study of YP-P10 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye (ICECAP 1) (NCT05467293) | Yuyu Pharma, Inc. | 2022-06-27 |
| Pembrolizumab in Combination With R-ICE Chemotherapy in Relapsed/Refractory Diffuse Large B-cell Lymphoma (NCT05221645) | University of Southampton | 2022-06-27 |
| A Study to Evaluate the Efficacy and Safety of DA-1229 (Evogliptin) in Patient's Calcific Aortic Valve Disease With Mild to Moderate Aortic Stenosis (EVOID-AS) (NCT05143177) | REDNVIA Co., Ltd. | 2022-06-27 |
| Study of ARO-MUC5AC in Healthy Subjects and Patients With Muco-Obstructive Lung Disease (NCT05292950) | Arrowhead Pharmaceuticals | 2022-06-27 |
| (Summit) A Study to Evaluate the Efficacy and Safety of CGT9486 Versus Placebo in Patients With Indolent or Smoldering Systemic Mastocytosis (NCT05186753) | Cogent Biosciences, Inc. | 2022-06-27 |
| A Dose-Finding Study in Japanese Patients to Evaluate the Effect of Obicetrapib as an Adjunct to Stable Statin Therapy. (NCT05421078) | NewAmsterdam Pharma | 2022-06-27 |
| A Study to Assess Subcutaneous Lirentelimab (AK002) in Atopic Dermatitis (NCT05155085) | Allakos Inc. | 2022-06-27 |
| Atezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer (NCT05312671) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2022-06-27 |
| A Study of AK112 With or Without AK117 in Metastatic Colorectal Cancer (NCT05382442) | Akeso | 2022-06-27 |
| Efficacy and Safety After Multiple Doses of TNP-2198 Capsules, Rabeprazole Sodium Enteric-coated Tablets and Amoxicillin Capsules in Helicobacter Pylori Infected-positive Participants (NCT06076694) | TenNor Therapeutics (Suzhou) Limited | 2022-06-26 |
| Cardiometabolic Effects of Dapagliflozin in Heart Failure With Reduced or Mildly Reduced Ejection Fraction (NCT05420285) | Assistance Publique - Hôpitaux de Paris | 2022-06-26 |
| AZA + Venetoclax as Maintenance Therapy in Younger Adults With AML in First Remission (NCT05404906) | The First Affiliated Hospital of Soochow University | 2022-06-25 |
| A Single Arm Phase II Study to Evaluate Treatment With Gevokizumab in Patients With Stage II/III Colon Cancer Who Are ctDNA-positive After Curative Surgery and Adjuvant Chemotherapy (NCT05178576) | NSABP Foundation Inc | 2022-06-24 |
| A Clinical Trial to Evaluate the Effect of IAE0972 in Patients With Advanced Malignant Solid Tumors. (NCT05396339) | SUNHO（China）BioPharmaceutical CO., Ltd. | 2022-06-24 |
| Study of MGTA-145 and Plerixafor in Patients With Sickle Cell Disease (NCT05445128) | Ensoma | 2022-06-24 |
| Empagliflozin and Anakinra for the Treatment of Postprandial Hypoglycemia in Patients With Prediabetes (NCT05174507) | University Hospital, Basel, Switzerland | 2022-06-24 |
| Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies (NCT05417594) | AstraZeneca | 2022-06-24 |
| Intravesical Recombinant BCG Followed by Perioperative Chemo-immunotherapy for Patients With MIBC (NCT04630730) | Swiss Cancer Institute | 2022-06-24 |
| Study of Safety, PK, and Efficacy of Multiple Ascending Doses of HZBio1 in Patients With Gout (NCT07752810) | Hangzhou Grand Biologic Pharmaceutical, Inc. | 2022-06-23 |
| Tislelizumab Combined with Mitoxantrone Hydrochloride Liposome in Extranodal Natural Killer/T Cell Lymphoma (NCT05464433) | Sun Yat-sen University | 2022-06-23 |
| Dose-Ranging Study of the Efficacy and Safety of TAK-101 for Prevention of Gluten-Specific T Cell Activation in Participants With Celiac Disease on a Gluten-Free Diet (NCT04530123) | Takeda | 2022-06-23 |
| Venetoclax and Azacitidine for Treatment of Therapy Related or Secondary Myelodysplastic Syndrome (NCT05379166) | Uma Borate | 2022-06-23 |
| Study Assessing CLENPIQ as Bowel Preparation for Pediatric Colonoscopy (NCT04113382) | Ferring Pharmaceuticals | 2022-06-23 |
| A Phase II Trial of Bicalutamide in Patients Receiving Intravesical BCG for Non-muscle Invasive Bladder Cancer (NCT05327647) | CHU de Quebec-Universite Laval | 2022-06-23 |
| Personalized Trials for Stress Management Against Standard of Care (NCT05408832) | Northwell Health | 2022-06-23 |
| Safety, Tolerability and Efficacy of QRX003 Lotion in Subjects With Netherton Syndrome (NCT05521438) | Quoin Pharmaceuticals | 2022-06-23 |
| INP105 Proof-of-concept Study for the Acute Treatment of Agitation in Adolescents and Young Adults With ASD (NCT05163717) | Impel Pharmaceuticals | 2022-06-23 |
| The Effect of Inflammation in Heart Failure (NCT05330013) | National Heart, Lung, and Blood Institute (NHLBI) | 2022-06-23 |
| Efficacy and Safety Study of Ravulizumab IV in Pediatric Participants With NMOSD (NCT05346354) | Alexion Pharmaceuticals, Inc. | 2022-06-23 |
| Study of Mivavotinib (CB-659) in Relapsed/Refractory Diffuse Large B-Cell Lymphoma (DLBCL) (NCT05319028) | Calithera Biosciences, Inc | 2022-06-23 |
| A Study to Learn How Well the Treatment Combination of Finerenone and Empagliflozin Works and How Safe it is Compared to Each Treatment Alone in Adult Participants With Long-term Kidney Disease (Chronic Kidney Disease) and Type 2 Diabetes (NCT05254002) | Bayer | 2022-06-23 |
| A First-in-Human Study of XSTEM-OA in Patients With Knee Osteoarthritis (NCT05344157) | Xindu Pty Ltd | 2022-06-22 |
| The Prospective Evaluation of Peri-Operative Glucocorticoid Use in the Management of Cervicofacial Infections of Odontogenic Origin (NCT05951504) | University of Manitoba | 2022-06-22 |
| Cannabidiol (CBD) in Pain Reduction for Knee Osteoarthritis (NCT05020028) | NYU Langone Health | 2022-06-22 |
| Preventive Effect of Clopidogrel on the Systemic Sclerosis Development Risk (NCT05098704) | University Hospital, Bordeaux | 2022-06-22 |
| A Clinical Trial to Evaluate Effect of IAP0971 in Patients With Advanced Malignant Tumors (NCT05396391) | SUNHO（China）BioPharmaceutical CO., Ltd. | 2022-06-22 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603 Administered Alone or in Combination With Aflibercept or Faricimab in Participants With Diabetic Macular Edema (NCT06850922) | Genentech, Inc. | 2022-06-22 |
| Effects of Mepivacaine on the Neurological Sequelae of Cerebral Infarction (NCT05222828) | Assistance Publique - Hôpitaux de Paris | 2022-06-22 |
| Pilot Study: Oral Treatment of American Tegumentary Leishmaniasis (Cutaneous and Mucosal Forms) in the Elderly (NCT06040489) | University of Brasilia | 2022-06-22 |
| Study to Evaluate The Safety and Efficacy of Balovaptan in Participants With Acute Ischemic Stroke at a High Risk of Developing Malignant Brain Edema (NCT05399550) | Hoffmann-La Roche | 2022-06-22 |
| Cold Stored Platelet in Hemorrhagic Shock (NCT04667468) | Jason Sperry | 2022-06-21 |
| A HIV Vaccine Trial in Individuals Who Started Antiretrovirals During Primary or Chronic Infection (EHVA T02) (NCT04120415) | ANRS, Emerging Infectious Diseases | 2022-06-21 |
| Study of Magrolimab and Pembrolizumab in Relapsed or Refractory Classic Hodgkin Lymphoma (NCT04788043) | Ranjana Advani | 2022-06-21 |
| A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer (NCT05451849) | TCR2 Therapeutics | 2022-06-21 |
| A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study) (NCT05462106) | AC Immune SA | 2022-06-21 |
| Phase II Trial of Venetoclax and Rituximab as Initial Therapy in Older Patients With Mantle Cell Lymphoma (NCT05025423) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2022-06-21 |
| Study of AD981 Versus Placebo in Obesity Hypoventilation Syndrome (NCT05448443) | Istituto Auxologico Italiano | 2022-06-21 |
| Nebulized Bacteriophage Therapy in Cystic Fibrosis Patients With Chronic Pseudomonas Aeruginosa Pulmonary Infection (NCT05010577) | BiomX, Inc. | 2022-06-21 |
| A Study of SOT101 in Combination With Pembrolizumab to Evaluate the Efficacy and Safety in Patients With Selected Advanced Solid Tumors (NCT05256381) | SOTIO Biotech AG | 2022-06-21 |
| Phase 2 Study of Bintrafusp Alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON). (NCT05012098) | National Cancer Institute (NCI) | 2022-06-21 |
| A Study of Loncastuximab Tesirine and Rituximab (Lonca-R) in Previously Untreated Unfit/Frail Participants With Diffuse Large B-cell Lymphoma (DLBCL) (NCT05144009) | ADC Therapeutics S.A. | 2022-06-21 |
| Adenosine 2A Receptor Antagonism and AIH in ALS (NCT05377424) | University of Florida | 2022-06-21 |
| Open-label of Loncastuximab Tesirine (ADCT-402) in Relapsed/Refractory Marginal Zone Lymphoma (NCT05296070) | University of Miami | 2022-06-21 |
| Project Engage: Oral PrEP Acceptability (NCT05458765) | Eastern Virginia Medical School | 2022-06-21 |
| ACD440 Gel in Peripheral Neuropathic Pain (NCT05416931) | AlzeCure Pharma | 2022-06-20 |
| Neoadjuvant Combination Therapy of Lenvatinib and TACE for Transplant-Eligible Large Hepatocellular Carcinoma Patients (NCT05171335) | The Methodist Hospital Research Institute | 2022-06-20 |
| Oral Decitabine/Cedazuridine (DEC-C) in Combination With Nivolumab for Patients With Mucosal Melanoma (NCT05089370) | University of Colorado, Denver | 2022-06-20 |
| Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas (NCT05130866) | Recursion Pharmaceuticals Inc. | 2022-06-20 |
| Pamiparib for Consolidation Treatment of Unprogressed LS-SCLC After Concurrent Chemoradiotherapy (NCT05483543) | Fudan University | 2022-06-20 |
| PD1 and PARP for Maintenance Therapy in NSLLC (NCT05392686) | Tianjin Medical University Cancer Institute and Hospital | 2022-06-20 |
| Study of Tislelizumab Combined With DisitamabVedotin and Pyrotinib Maleate in HER2-positive or Mutated Advanced Colorectal Cancer Who Failed Standard Therapy (NCT05350917) | The First Affiliated Hospital of Zhengzhou University | 2022-06-20 |
| MRD-guided Adjuvant Tislelizumab and Chemotherapy in Resected Stage IIA-IIIB NSCLC (NCT05286957) | The First Affiliated Hospital of Zhengzhou University | 2022-06-20 |
| Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial) (NCT04772222) | University of Utah | 2022-06-20 |
| Whole-target Consolidation Therapy Under Systemic Therapy for Oligometastatic Nasopharyngeal Carcinoma (NCT05431764) | Sun Yat-sen University | 2022-06-20 |
| Pertussis Challenge Study in Adults Vaccinated With BPZE1 (NCT05461131) | ILiAD Biotechnologies | 2022-06-20 |
| Nebulised Heparin in Patients With COVID-19 Pneumonia (NCT05255848) | Lady Reading Hospital, Pakistan | 2022-06-20 |
| A Study Evaluating the Safety, Tolerability, Pharmacokinetic and Efficacy of HLX301(TIGIT×PDL1 Bispecific) in Locally Advanced/Metastatic Solid Tumors or Lymphoma (NCT05390528) | Shanghai Henlius Biotech | 2022-06-20 |
| The ORTIZ Study: Optimising RASi Therapy With SZC (NCT04983979) | Barts & The London NHS Trust | 2022-06-17 |
| Phase 2a Study to Evaluate Suppression of Radiotherapy-induced Mucositis by TK112690 (NCT05658016) | Tosk, Inc. | 2022-06-17 |
| Ferric Citrate and Chronic Kidney Disease in Children (NCT04741646) | University of California, Los Angeles | 2022-06-17 |